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This is the first version of the
decider
package on github. -
Functions for scenario evaluation and simulation of a hierarchical/joint BLRM for two-drug combination therapy are provided, allowing in particular for trial designs consisting of concurrent monotherapy and combination therapy escalation, including potentially data from historical trials.
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The main functions are:
scenario_jointBLRM()
andsim_jointBLRM
. Both functions have a second version that additionally allows to the use of a binary covariate.