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DESCRIPTION
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DESCRIPTION
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Package: TOP
Title: TOP Constructs Transferable Model Across Gene Expression Platforms
Version: 0.99.11
Date: 2022-11-09
Authors@R:
c(
person(
given="Harry", family="Robertson",
email = "harry.robertson@sydney.edu.au", role = c("aut", "cre"),
comment = c(ORCID = "0000-0001-9203-3894")
),
person(
given="Nicholas", family= "Robertson",
email = "nicholas.robertson@sydney.edu.au", role = c("aut")
)
)
Description: TOP constructs a transferable model across gene expression platforms for prospective experiments. Such a transferable model can be trained to make predictions on independent validation data with an accuracy that is similar to a re-substituted model. The TOP procedure also has the flexibility to be adapted to suit the most common clinical response variables, including linear response, binomial and Cox PH models.
License: GPL-3
URL: https://github.com/Harry25R/TOP
BugReports: https://github.com/Harry25R/TOP/issues
biocViews: Software, Survival, GeneExpression
Encoding: UTF-8
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.2.3
Imports:
assertthat,
caret,
ClassifyR,
directPA,
doParallel,
dplyr,
ggnewscale,
ggplot2,
ggraph,
ggrepel,
ggthemes,
glmnet,
Hmisc,
igraph,
latex2exp,
limma,
magrittr,
methods,
plotly,
pROC,
purrr,
reshape2,
stats,
stringr,
survival,
tibble,
tidygraph,
tidyr,
statmod
Suggests: knitr, rmarkdown, BiocStyle, Biobase, curatedOvarianData, ggbeeswarm, ggsci, survminer, tidyverse
VignetteBuilder: knitr
LazyData: false