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PR #91 provides a way to build Smith-Waterman and PairHMM in a standalone C library. It hasn't been merged yet because we haven't had time to review it.
If you would like to give the PR a try, we would welcome your feedback.
No GATK-independent API is provided for the accelerated smith waterman implementation. It would be quite useful to be able to use this implementation to replace http://jaligner.sourceforge.net or the java bindings I wrote for https://github.com/mengyao/Complete-Striped-Smith-Waterman-Library.
Are there any plans to release a stand-alone AVX accelerated S/W implementation?
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