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InhibitoryCortex_pulse_2d_FullWithRep_0905.m
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InhibitoryCortex_pulse_2d_FullWithRep_0905.m
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clear
clc
close all
%% Parameters
numcells=500;
endtime=2000;
pulsetime=1000;
dt=.01;
steps=endtime/dt+1;
probii=[8 12 16];
std=6;
% probii=12;
% std=[3 6 12];
gsynrange=0.25:.25:5;
%% Input data from csv files
filenames=cell(2,3);
for i=1:2
for j=1:3
if i==1
filenames{i,j}=sprintf('Full_prepulse_state0_probii%1.0d_std%1.0d_REP.csv', probii(j), std);
elseif i==2
filenames{i,j}=sprintf('Full_prepulse_state1_probii%1.0d_std%1.0d_REP.csv', probii(j), std);
end
end
end
%% Choose gsyn to plot
gsynrange=.25:.25:5;
Irange=100:25:1000;
for gsynchoose=1:10
%% Pull Synchrony Traces
Sync0=zeros(3, 37);
Sync1=zeros(3, 37);
for j=1:3
temp1=csvread(filenames{1,j});
temp2=csvread(filenames{2,j});
Sync0(j,:)=temp1(1:37,gsynchoose);
Sync1(j,:)=temp2(1:37,gsynchoose);
end
maximum=max(max([Sync0, Sync1]));
%% Calculate Slopes
slope0=zeros(3,3);
slope1=zeros(3,3);
for j=1:3
check1=Sync0(j,:);
check2=Sync1(j,:);
I11=find(check1>maximum/2, 1);
I12=find(check2>maximum/2, 1);
% I21=find(check1(1:I11)<.15, 1, 'last');
% I22=find(check2(1:I12)<.15, 1, 'last');
I21=I11-1;
I22=I12-1;
if (I11>0)
slope0(j,1)=(check1(I11)-check1(I21))/(Irange(I11)-Irange(I21));
slope0(j,2)=Irange(ceil((I21+I11)/2));
slope0(j,3)=check1(ceil((I21+I11)/2));
else
slope0(j,1)=0;
slope0(j,2)=500+(j-1)*100;
slope0(j,3)=.025;
end
if (I12>0)
slope1(j,1)=(check2(I12)-check2(I22))/(Irange(I12)-Irange(I22));
slope1(j,2)=Irange(ceil((I22+I12)/2));
slope1(j,3)=check2(ceil((I22+I12)/2));
else
slope1(j,1)=0;
slope1(j,2)=500+(j-1)*100;
slope1(j,3)=.025;
end
end
if abs(slope0(1,3)-slope0(2,3))<(maximum/50)
slope0(2,3)=slope0(2,3)+(maximum/10);
end
if abs(slope0(2,3)-slope0(3,3))<(maximum/50)
slope0(3,3)=slope0(3,3)+(maximum/10);
end
if abs(slope0(3,3)-slope0(1,3))<(maximum/50)
slope0(1,3)=slope0(1,3)-(maximum/10);
end
if abs(slope1(1,3)-slope1(2,3))<(maximum/50)
slope1(2,3)=slope1(2,3)+(maximum/10);
end
if abs(slope1(2,3)-slope1(3,3))<(maximum/50)
slope1(3,3)=slope1(3,3)+(maximum/10);
end
if abs(slope1(3,3)-slope1(1,3))<(maximum/50)
slope1(1,3)=slope1(1,3)-(maximum/10);
end
%% Plot 2D Synchrony Trajectories
figure('units','normalized','position',[0 0 1 1])
subaxis(1,2,1, 'Spacing', 0.01, 'Padding', 0.05, 'Margin', 0.05, 'PaddingBottom', 0.12, 'PaddingTop', 0.075, 'PaddingLeft', 0.07, 'PaddingRight', 0.01);
plot(Irange, Sync0(1,:), 'b-', 'LineWidth', 2);
hold on
plot(Irange, Sync0(2,:), 'g-', 'LineWidth', 2);
hold on
plot(Irange, Sync0(3,:), 'r-', 'LineWidth', 2);
hold on
% str=sprintf('Slope=%1.4f', slope0(1,1));
% text(slope0(1,2), slope0(1,3), str, 'HorizontalAlignment', 'right', 'Color', 'b', 'FontSize', 20);
% hold on
% str=sprintf('Slope=%1.4f', slope0(2,1));
% text(slope0(2,2), slope0(2,3), str, 'HorizontalAlignment', 'right', 'Color', 'g', 'FontSize', 20);
% hold on
% str=sprintf('Slope=%1.4f', slope0(3,1));
% text(slope0(3,2), slope0(3,3), str, 'HorizontalAlignment', 'right', 'Color', 'r', 'FontSize', 20);
legend('Connection Probability=0.08', 'Connection Probability=0.12', 'Connection Probability=0.16', 'Location', 'SouthEast')
% legend('Standard Deviation=3 pA', 'Standard Deviation=6 pA', 'Standard Deviation=12 pA', 'Location', 'SouthEast')
axis([100 1000 0 maximum+.05])
set(gca, 'FontSize', 20);
% xlabel({'Average External'; 'Applied Current (pA)'}, 'FontSize', 26)
ylabel('Synchrony Measure', 'FontSize', 26)
title('Control', 'FontSize', 30);
subaxis(1,2,2, 'Spacing', 0.01, 'Padding', 0.05, 'Margin', 0.05, 'PaddingBottom', 0.12, 'PaddingTop', 0.075, 'PaddingLeft', 0.07, 'PaddingRight', 0.01);
plot(Irange, Sync1(1,:), 'b-', 'LineWidth', 2);
hold on
plot(Irange, Sync1(2,:), 'g-', 'LineWidth', 2);
hold on
plot(Irange, Sync1(3,:), 'r-', 'LineWidth', 2);
hold on
% str=sprintf('Slope=%1.4f', slope1(1,1));
% text(slope1(1,2), slope1(1,3), str, 'HorizontalAlignment', 'right', 'Color', 'b', 'FontSize', 20);
% hold on
% str=sprintf('Slope=%1.4f', slope1(2,1));
% text(slope1(2,2), slope1(2,3), str, 'HorizontalAlignment', 'right', 'Color', 'g', 'FontSize', 20);
% hold on
% str=sprintf('Slope=%1.4f', slope1(3,1));
% text(slope1(3,2), slope1(3,3), str, 'HorizontalAlignment', 'right', 'Color', 'r', 'FontSize', 20);
legend('Connection Probability=0.08', 'Connection Probability=0.12', 'Connection Probability=0.16', 'Location', 'SouthEast')
% legend('Standard Deviation=3 pA', 'Standard Deviation=6 pA', 'Standard Deviation=12 pA', 'Location', 'SouthEast')
axis([100 1000 0 maximum+.05])
set(gca, 'FontSize', 20);
% xlabel({'Average External'; 'Applied Current (pA)'}, 'FontSize', 26)
ylabel('Synchrony Measure', 'FontSize', 26)
title('4-AP', 'FontSize', 30);
supAxis=[.0750 .15 .85 .8];
str1= sprintf('Average External Applied Current (pA)');
str3= sprintf('gsyn=%1.2f', gsynrange(gsynchoose));
[ax,h]=suplabel(str1, 'x', supAxis);
set(h, 'FontSize', 26);
[ax3,h3]=suplabel(str3, 't', supAxis);
set(h3, 'FontSize', 20);
str1=sprintf('2d_std%1.0f_gsyn%1.0fREP_final1_2.png', std, gsynrange(gsynchoose)*100);
str2=sprintf('2d_std%1.0f_gsyn%1.0fREP_final1_2.fig', std, gsynrange(gsynchoose)*100);
% str1=sprintf('2d_probii%1.0f_gsyn%1.0fREP_final1_2.png', probii, gsynrange(gsynchoose)*100);
% str2=sprintf('2d_probii%1.0f_gsyn%1.0fREP_final1_2.fig', probii, gsynrange(gsynchoose)*100);
saveas(gcf, str2)
set(gcf,'PaperPositionMode','auto')
print(str1, '-dpng', '-r0');
end