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Conversion to MetanetX namespace #11

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zoey-rw opened this issue Jan 26, 2024 · 0 comments
Open

Conversion to MetanetX namespace #11

zoey-rw opened this issue Jan 26, 2024 · 0 comments

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@zoey-rw
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zoey-rw commented Jan 26, 2024

I'm interested in converting this model to the MetanetX namespace, to make multi-species modeling a bit easier. With the current SBML file, the MNX importer wants to merge 4 reactions, including two NGAM reactions (r_4046 and r_4046_sce), which I figure were distinct for a reason:

Screenshot 2024-01-25 at 10 17 26 PM

Also, MetanetX won't map any metabolites by their IDs (even though over 40 metabolites have MetanetX identifiers in the annotations). So I started mapping metabolite IDs to MNX using their CHEBI/KEGG annotations, but this seems to increase the number of reactions that the MNX importer finds problematic or wants to drop entirely (possibly because of how I was trying to preserve any m_ or s_ prefixes, but didn't match MNX IDs for both the s_ or m_? Not sure.)
Since Yeastnet v8_3_4 is in the MNX repository, I wanted to reach out in case the importer problems may have already been identified or solved.

Alternatively, to avoid the MNX importer merging reactions, I would appreciate any advice for changing metabolite IDs to their MNX annotations! Thanks!

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