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vacuolar protein processing PTN001121786/PTN000337666 #5474

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ValWood opened this issue Oct 13, 2024 · 2 comments
Open

vacuolar protein processing PTN001121786/PTN000337666 #5474

ValWood opened this issue Oct 13, 2024 · 2 comments
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@ValWood
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ValWood commented Oct 13, 2024

Both are readouts, have been removed from SGD

  • PTHR ID & PTN node:

GO:0006624 | vacuolar protein processing | IBA with S000006157 , PTN001121786

GO:0006624 | vacuolar protein processing | IBA with S000004055 , PTN000337666

  • Sequences with problematic annotation (ID + gene/protein name):

  • Type of Issue: Erroneous source or erroneous propagation, or other issue

  • Add the label 'high priority' if needed. Generally high priority issues affect a lot of proteins, and annotations are incorrect (as opposed to just imprecise).

@pgaudet
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pgaudet commented Oct 14, 2024

If all annotations are readouts, should term be obsoleted?

@ValWood
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ValWood commented Oct 14, 2024

I did wonder about that, but I don't think so. All annotations for this paper were readouts (because the assay can identify anything from the proteins required for the processing events entering the secretory pathway onwards, but there are genes that are involved more directly in "vacuolar protein processing".
Most of the remaining annotations are to the protease, but there will be other GPs which affect this process more directly by activating the protease etc.

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