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Create distinct activity instances per gene product -> gene product pair #3

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dustine32 opened this issue Mar 30, 2018 · 2 comments
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@dustine32
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An MF should be a distinct instance if it has a different molecular target (for SIGNOR this is interactor B). We should capture the target with has input: (interactor A) <-enabled by-(MF)-has input->(interactor B). So in most cases this means that each line of the SIGNOR file will give a distinct instance of an MF.

@dustine32 dustine32 changed the title Only one distinct gene product instance per pathway Create distinct activity instances per gene product -> gene product pair Mar 30, 2018
@dustine32 dustine32 self-assigned this Mar 30, 2018
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dustine32 commented Mar 30, 2018

Removed the check that reuses MFs connected to a GP and instead just creates a new MF for each line.

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Also added "has input" relations from entity A's MF to B's GP. Example for "MYC has input CDKN2B":
image
http://68.181.125.171:8910/editor/graph/gomodel:6f188b77-e6bd-4c9a-bdb0-7c4d0f03b4bc

Can also write some SPARQL to simply count MF individuals and compare to # of lines.

dustine32 added a commit that referenced this issue Mar 30, 2018
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