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Choose only one MF per A -> B interactor pair #4

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dustine32 opened this issue Mar 30, 2018 · 1 comment
Open

Choose only one MF per A -> B interactor pair #4

dustine32 opened this issue Mar 30, 2018 · 1 comment
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@dustine32
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If, in the same pathway, there are two MFs where the enabled by is the same (interactor A) and the target is the same (interactor B), you should accept one over the other according to precedence rules, and if there’s no rule just report an error and we’ll review it. The one precedence rule we can state now is that protein kinase activity should be chosen over protein binding. So for ATM acting on ABL1, you’ll only have one activity (protein kinase).

@dustine32
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I added a filter specifically for this rule that removes all non-"protein kinase activity" interaction lines if the only lines are either protein kinase activity or protein binding.

So for ATM to ABL1, this removed the extra "protein binding" relation. Before:
image

After:
image
http://68.181.125.171:8910/editor/graph/gomodel:6f188b77-e6bd-4c9a-bdb0-7c4d0f03b4bc

@dustine32 dustine32 self-assigned this Mar 30, 2018
dustine32 added a commit that referenced this issue Mar 30, 2018
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