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Hi Dave,
I read you script, and noticed that RO is calculated by ref_seq+ref_span. and ref_seq is calculated by the following code.
# svtyper/svtyper/singlesample.py line 255 to 259 is_ref_seq_A=sam_fragment.is_ref_seq(read, None, chromA, posA, ciA, min_aligned)
is_ref_seq_B=sam_fragment.is_ref_seq(read, None, chromB, posB, ciB, min_aligned)
if (is_ref_seq_Aoris_ref_seq_B):
p_reference=prob_mapq(read)
ref_seq+=p_reference
I'm wondering that if this read has a paired end read that overlaps with it a lot (shown as the illustration below), will svtyper take read1 and read2 as two independent observations?
The text was updated successfully, but these errors were encountered:
Hi Dave,
I read you script, and noticed that RO is calculated by ref_seq+ref_span. and
ref_seq
is calculated by the following code.I'm wondering that if this
read
has a paired end read that overlaps with it a lot (shown as the illustration below), will svtyper take read1 and read2 as two independent observations?The text was updated successfully, but these errors were encountered: