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Ribo-Seq data that is prepared with MNase rather than RNase will not pass most 3nt periodicity checks. It doesn't necessarily mean it is poor quality data just that its purposes may be different. For quantification it may be perfectly fine.
3nt periodicity is most important for ORF calling. So this check may be best places a the start of that branch. This is actually once of the most awkward aspects of running RiboCode as it checks this periodicity in quite a naive way.
Completely understandable. I would just argue that it's placement within the pipeline can make a big difference to the types of Ribo-Seq libraries we can work with.
Also, my own application RiboMetric would likely have been a good fit for this and many other aspects but even I won't advocate for it's inclusion yet. Once I have done a bit more development and get it on bioconda I will see where it will fit best
Description of feature
Ensure one of the modules installed can perform this check.
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