diff --git a/test/test_transforms_v2_refactored.py b/test/test_transforms_v2_refactored.py
index 69180b99dbc..64a79262f3e 100644
--- a/test/test_transforms_v2_refactored.py
+++ b/test/test_transforms_v2_refactored.py
@@ -26,6 +26,8 @@
     make_video,
     set_rng_seed,
 )
+
+from torch import nn
 from torch.testing import assert_close
 from torchvision import datapoints
 
@@ -1634,3 +1636,64 @@ def test_transform_negative_degrees_error(self):
     def test_transform_unknown_fill_error(self):
         with pytest.raises(TypeError, match="Got inappropriate fill arg"):
             transforms.RandomAffine(degrees=0, fill="fill")
+
+
+class TestCompose:
+    class BuiltinTransform(transforms.Transform):
+        def _transform(self, inpt, params):
+            return inpt
+
+    class PackedInputTransform(nn.Module):
+        def forward(self, sample):
+            assert len(sample) == 2
+            return sample
+
+    class UnpackedInputTransform(nn.Module):
+        def forward(self, image, label):
+            return image, label
+
+    @pytest.mark.parametrize(
+        "transform_clss",
+        [
+            [BuiltinTransform],
+            [PackedInputTransform],
+            [UnpackedInputTransform],
+            [BuiltinTransform, BuiltinTransform],
+            [PackedInputTransform, PackedInputTransform],
+            [UnpackedInputTransform, UnpackedInputTransform],
+            [BuiltinTransform, PackedInputTransform, BuiltinTransform],
+            [BuiltinTransform, UnpackedInputTransform, BuiltinTransform],
+            [PackedInputTransform, BuiltinTransform, PackedInputTransform],
+            [UnpackedInputTransform, BuiltinTransform, UnpackedInputTransform],
+        ],
+    )
+    @pytest.mark.parametrize("unpack", [True, False])
+    def test_packed_unpacked(self, transform_clss, unpack):
+        needs_packed_inputs = any(issubclass(cls, self.PackedInputTransform) for cls in transform_clss)
+        needs_unpacked_inputs = any(issubclass(cls, self.UnpackedInputTransform) for cls in transform_clss)
+        assert not (needs_packed_inputs and needs_unpacked_inputs)
+
+        transform = transforms.Compose([cls() for cls in transform_clss])
+
+        image = make_image()
+        label = 3
+        packed_input = (image, label)
+
+        def call_transform():
+            if unpack:
+                return transform(*packed_input)
+            else:
+                return transform(packed_input)
+
+        if needs_unpacked_inputs and not unpack:
+            with pytest.raises(TypeError, match="missing 1 required positional argument"):
+                call_transform()
+        elif needs_packed_inputs and unpack:
+            with pytest.raises(TypeError, match="takes 2 positional arguments but 3 were given"):
+                call_transform()
+        else:
+            output = call_transform()
+
+            assert isinstance(output, tuple) and len(output) == 2
+            assert output[0] is image
+            assert output[1] is label
diff --git a/torchvision/transforms/v2/_container.py b/torchvision/transforms/v2/_container.py
index fffef4157bd..8f591c49707 100644
--- a/torchvision/transforms/v2/_container.py
+++ b/torchvision/transforms/v2/_container.py
@@ -43,13 +43,16 @@ def __init__(self, transforms: Sequence[Callable]) -> None:
         super().__init__()
         if not isinstance(transforms, Sequence):
             raise TypeError("Argument transforms should be a sequence of callables")
+        elif not transforms:
+            raise ValueError("Pass at least one transform")
         self.transforms = transforms
 
     def forward(self, *inputs: Any) -> Any:
-        sample = inputs if len(inputs) > 1 else inputs[0]
+        needs_unpacking = len(inputs) > 1
         for transform in self.transforms:
-            sample = transform(sample)
-        return sample
+            outputs = transform(*inputs)
+            inputs = outputs if needs_unpacking else (outputs,)
+        return outputs
 
     def extra_repr(self) -> str:
         format_string = []