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DESCRIPTION
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DESCRIPTION
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Package: celegans.aging
Type: Package
Title: Aging-Related Changes of C. elegans Proteome
Version: 0.1
Date: 2015-05-29
Author: Vlad Petyuk
Maintainer: Vlad Petyuk <vladislav.petyuk@pnnl.gov>
Description: The packages introduces a collection of LC-MS/MS datasets
obtained on Caenorhabditis elegans nematodes at different times
of their lifespan. The discovery of proteins differentially abundant
between the young and old ages was performed using spectral counting
approach. Interrogation of the common biological functions of the
proteins with altered abundance revealed up-regulation of
DNA/RNA-related pathways (e.g. cell cycle and mRNA splicing)
and down-regulation of metabolic pathways (e.g. glycolysis and
glyconeogenesis)
License: Artistic-2.0
LazyData: TRUE
Depends: R (>= 3.2.0)
Suggests: BiocStyle, knitr, rpx, jsonlite, xtable, MSnID, MSnbase, biomaRt,
msmsTests, GOstats, org.Ce.eg.db, ReactomePA (>= 1.13.2),
DOSE (>= 2.7.6), graphite, KEGGREST, pathview
VignetteBuilder: knitr