diff --git a/pathways/WP2001/WP2001-bibliography.tsv b/pathways/WP2001/WP2001-bibliography.tsv new file mode 100644 index 000000000..6daf66eb3 --- /dev/null +++ b/pathways/WP2001/WP2001-bibliography.tsv @@ -0,0 +1,2 @@ +ID Database Citation +37986224 Pubmed "TarBase-v9.0 extends experimentally supported miRNA-gene interactions to cell-types and virally encoded miRNAs. Skoufos G, Kakoulidis P, Tastsoglou S, Zacharopoulou E, Kotsira V, Miliotis M, et al. Nucleic Acids Res. 2024 Jan 5;52(D1):D304–10. PubMed Europe PMC Scholia" diff --git a/pathways/WP2001/WP2001-datanodes.tsv b/pathways/WP2001/WP2001-datanodes.tsv new file mode 100644 index 000000000..84b6b228f --- /dev/null +++ b/pathways/WP2001/WP2001-datanodes.tsv @@ -0,0 +1,22 @@ +Label Type Identifier Comment Ensembl NCBI gene HGNC UniProt Wikidata ChEBI InChI PubChem ChemSpider HMDB KEGG LipidMaps +MIR92A2 GeneProduct ensembl:ENSG00000284538 "" ensembl:ENSG00000284538 ncbigene:407049 hgnc.symbol:MIR92A2 +CEBPB GeneProduct ensembl:ENSG00000172216 "" ensembl:ENSG00000172216 ncbigene:1051 hgnc.symbol:CEBPB uniprot:P17676 +MIR155 GeneProduct ensembl:ENSG00000275402 "" +PICALM GeneProduct ensembl:ENSG00000073921 "" ensembl:ENSG00000073921 ncbigene:8301 hgnc.symbol:PICALM uniprot:E9PJT1;uniprot:H0YCY1;uniprot:A0A024R5L7;uniprot:E9PI56;uniprot:E9PK13;uniprot:H0YD48;uniprot:H0YE97;uniprot:Q13492;uniprot:E9PKP6;uniprot:H0YEY8;uniprot:H0YEH1;uniprot:E9PLJ8;uniprot:H0YEF7;uniprot:A0A024R5P1 +FADS3 GeneProduct ensembl:ENSG00000149485 "" ensembl:ENSG00000149485 ncbigene:3992 hgnc.symbol:FADS1 uniprot:F5H2H3;uniprot:H0YB97;uniprot:F5H852;uniprot:F5H5X5;uniprot:C9JJB3;uniprot:F5H3U5;uniprot:F5H2R9;uniprot:F5H3P6;uniprot:C9J425;uniprot:F5H1Q7;uniprot:H7C2V0;uniprot:A0A0A0MR51;uniprot:F5H0Y2;uniprot:F5GWE3;uniprot:F5GYH4;uniprot:F5H8G5;uniprot:O60427 +PHC2 GeneProduct ensembl:ENSG00000134686 "" ensembl:ENSG00000134686 ncbigene:1912 hgnc.symbol:PHC2 uniprot:Q8IXK0;uniprot:B3KPJ4;uniprot:A0A0A0MSI2 +MIR20A GeneProduct ensembl:ENSG00000283762 "" ensembl:ENSG00000283762 ncbigene:406982 hgnc.symbol:MIR20A +LPL GeneProduct ensembl:ENSG00000175445 "" ensembl:ENSG00000175445 ncbigene:4023 hgnc.symbol:LPL uniprot:A0A3B3IT60;uniprot:P06858;uniprot:E5RJZ4;uniprot:A0A1B1RVA9;uniprot:E5RHN7;uniprot:E5RJI0;uniprot:E7EW14 +HIPK3 GeneProduct ensembl:ENSG00000110422 "" ensembl:ENSG00000110422 ncbigene:10114 hgnc.symbol:HIPK3 uniprot:Q9H422;uniprot:E9PKD7 +FUSIP1 GeneProduct ensembl:ENSG00000188529 "" ensembl:ENSG00000188529 ncbigene:10772 hgnc.symbol:SRSF10 uniprot:O75494;uniprot:R4GMP8;uniprot:A0A0S2Z504;uniprot:Q5JRI1;uniprot:Q6IQ42 +ELOVL5 GeneProduct ensembl:ENSG00000012660 "" ensembl:ENSG00000012660 ncbigene:60481 hgnc.symbol:ELOVL5 uniprot:A0A0A0MTI6;uniprot:Q9NYP7;uniprot:A0A024RD35 +MIR29C GeneProduct ensembl:ENSG00000284214 "" ensembl:ENSG00000284214 ncbigene:407026 hgnc.symbol:MIR29C +TMEM43 GeneProduct ensembl:ENSG00000170876 "" ensembl:ENSG00000170876 ncbigene:79188 hgnc.symbol:TMEM43 uniprot:F8WDL3;uniprot:Q9BTV4;uniprot:A0A024R2F9 +FADS1 GeneProduct ensembl:ENSG00000149485 "" ensembl:ENSG00000149485 ncbigene:3992 hgnc.symbol:FADS1 uniprot:F5H2H3;uniprot:H0YB97;uniprot:F5H852;uniprot:F5H5X5;uniprot:C9JJB3;uniprot:F5H3U5;uniprot:F5H2R9;uniprot:F5H3P6;uniprot:C9J425;uniprot:F5H1Q7;uniprot:H7C2V0;uniprot:A0A0A0MR51;uniprot:F5H0Y2;uniprot:F5GWE3;uniprot:F5GYH4;uniprot:F5H8G5;uniprot:O60427 +TGFBR2 GeneProduct ensembl:ENSG00000163513 "" ensembl:ENSG00000163513 ncbigene:7048 hgnc.symbol:TGFBR2 uniprot:D2JYI1;uniprot:P37173;uniprot:A3QNQ0 +IGF2R GeneProduct ensembl:ENSG00000197081 "" ensembl:ENSG00000197081 ncbigene:3482 hgnc.symbol:IGF2R uniprot:A0A7I2YQS7;uniprot:A0A7I2V657;uniprot:A0A7I2V381;uniprot:P11717;uniprot:S4R328 +SFRS9 GeneProduct ensembl:ENSG00000111786 "" ensembl:ENSG00000111786 ncbigene:8683 hgnc.symbol:SRSF9 uniprot:S4R3G0;uniprot:H0YIB4;uniprot:Q13242 +CYP1B1 GeneProduct ensembl:ENSG00000138061 "" ensembl:ENSG00000138061 ncbigene:1545 hgnc.symbol:CYP1B1 uniprot:A0A087WUQ7;uniprot:A0A087WW26;uniprot:Q16678 +CAP1 GeneProduct ensembl:ENSG00000131236 "" ensembl:ENSG00000131236 ncbigene:10487 hgnc.symbol:CAP1 uniprot:Q5T0R2;uniprot:Q5T0S3;uniprot:Q5T0R1;uniprot:Q5T0R8;uniprot:Q5T0R7;uniprot:Q5T0R9;uniprot:Q5T0R4;uniprot:Q5T0R3;uniprot:Q5T0R6;uniprot:Q01518;uniprot:Q5T0R5 +TMED10 GeneProduct ensembl:ENSG00000170348 "" ensembl:ENSG00000170348 ncbigene:10972 hgnc.symbol:TMED10 uniprot:G3V2K7;uniprot:A0A024R6I3;uniprot:P49755 +CSRP1 GeneProduct ensembl:ENSG00000159176 "" ensembl:ENSG00000159176 ncbigene:1465 hgnc.symbol:CSRP1 uniprot:A0A087X134;uniprot:P21291;uniprot:E9PND2;uniprot:E9PP21;uniprot:E9PS42;uniprot:A0A384P5K2 diff --git a/pathways/WP2001/WP2001.gpml b/pathways/WP2001/WP2001.gpml new file mode 100644 index 000000000..6b201fd77 --- /dev/null +++ b/pathways/WP2001/WP2001.gpml @@ -0,0 +1,313 @@ + + + This cataloge pathway was created using the database from http://diana.cslab.ece.ntua.gr/tarbase/ with exclusions based on evidence type. This pathway only includes miR targeted genes expressed in Adipocyte cells. This pathway is meant for data mapping. + b99 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + 37986224 + PubMed + TarBase-v9.0 extends experimentally supported miRNA-gene interactions to cell-types and virally encoded miRNAs. + Nucleic Acids Res + 2024 + Skoufos G + Kakoulidis P + Tastsoglou S + Zacharopoulou E + Kotsira V + Miliotis M + Mavromati G + Grigoriadis D + Zioga M + Velli A + Koutou I + Karagkouni D + Stavropoulos S + Kardaras FS + Lifousi A + Vavalou E + Ovsepian A + Skoulakis A + Tasoulis SK + Georgakopoulos SV + Plagianakos VP + Hatzigeorgiou AG + + + adipocyte + CL:0000136 + Cell Type + + + miRNA pathway + PW:0000808 + Pathway Ontology + + + + diff --git a/pathways/WP2001/WP2001.json b/pathways/WP2001/WP2001.json new file mode 100644 index 000000000..e33b30664 --- /dev/null +++ b/pathways/WP2001/WP2001.json @@ -0,0 +1,2890 @@ +{ + "entitiesById": { + "a3188": { + "drawAs": "rect", + "fill": "#ffffff", + "fontFamily": "Arial", + "fontSize": 10, + "fontStyle": "normal", + "fontWeight": "normal", + "gpmlElementName": "DataNode", + "height": 20, + "id": "a3188", + "kaavioType": "SingleFreeNode", + "lineHeight": 1.1, + "overflow": "hidden", + "padding": 8, + "stroke": "#990099", + "strokeWidth": 1, + "textAlign": "center", + "textContent": "MIR19B2", + "textDecoration": "none", + "textOverflow": "clip", + "type": [ + "DataNode", + "SingleFreeNode", + "Ensembl:ENSG00000207812", + "Rna" + ], + "verticalAlign": "middle", + "whiteSpace": "pre", + "width": 80, + "wpType": "Rna", + 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"Stavropoulos S", + "Kardaras FS", + "Lifousi A", + "Vavalou E", + "Ovsepian A", + "Skoulakis A", + "Tasoulis SK", + "Georgakopoulos SV", + "Plagianakos VP", + "Hatzigeorgiou AG" + ], + "gpmlElementName": "PublicationXref", + "id": "publicationXrefb99", + "source": "Nucleic Acids Res", + "standardName": "TarBase-v9.0 extends experimentally supported miRNA-gene interactions to cell-types and virally encoded miRNAs.", + "textContent": "1", + "type": [ + "PublicationXref", + "PubMed:37986224" + ], + "xrefDataSource": "PubMed", + "xrefIdentifier": "37986224", + "year": 2024 + } + }, + "pathway": { + "@context": [ + "https://cdn.rawgit.com/wikipathways/WpVocabularies/7a46a05/contexts/pvjs.jsonld", + { + "@base": "WP2001/" + } + ], + "author": "[Samuel Sklar, MaintBot, MartijnVanIersel, Egonw, Khanspers, Eweitz]", + "comments": [ + { + "content": "This cataloge pathway was created using the database from http://diana.cslab.ece.ntua.gr/tarbase/ with exclusions based on evidence type. This pathway only includes miR targeted genes expressed in Adipocyte cells. This pathway is meant for data mapping.", + "source": "WikiPathways-description" + } + ], + "contains": [ + "id55a5dc30", + "id5e4bb8bb", + "id71f45567", + "id7b75984d", + "idec2a559f", + "idf643a685", + "id9007ca26", + "idb8e8f6b5", + "ide63952e", + "id7c3568bf", + "id2ef2aa37", + "idb2e2c34e", + "a3188", + "a3857", + "a5016", + "b1cfd", + "b81b9", + "c04b3", + "c0a9f", + "cfa14", + "d4dc4", + "d5614", + "db851", + "e3d54", + "e825b", + "f23d6", + "f5385", + "f657e", + "ab2a2", + "be6ec", + "d0841", + "d7c21", + "d9eb4", + "dd144", + "ddb73", + "f7702" + ], + "dataSourceVersion": "WP2001_r135700", + "displayName": "miR-targeted genes in adipocytes", + "drawAs": "rect", + "fill": "white", + "fontSize": 12, + "fontWeight": "bold", + "gpmlElementName": "Pathway", + "height": 478.4881023177917, + "id": "WP2001", + "kaavioType": "Group", + "lastModified": "20241027162249", + "name": "miR-targeted genes in adipocytes", + "organism": "Homo sapiens", + "padding": 5, + "pathwayVersion": "WP2001", + "standardName": "miR-targeted genes in adipocytes", + "stroke": "black", + "strokeWidth": 0, + "textAlign": "left", + "textContent": "Name: miR-targeted genes in adipocytes\nLast Modified: 20241027162249\nOrganism: Homo sapiens", + "type": [ + "Pathway", + "http://identifiers.org/pw/PW:0000808" + ], + "verticalAlign": "top", + "width": 733.1831275720165, + "x": 0, + "y": 0, + "zIndex": 0 + } +} diff --git a/pathways/WP2001/WP2001.png b/pathways/WP2001/WP2001.png new file mode 100644 index 000000000..d37f8b1fe Binary files /dev/null and b/pathways/WP2001/WP2001.png differ diff --git a/pathways/WP2001/WP2001.svg b/pathways/WP2001/WP2001.svg new file mode 100644 index 000000000..a8d3de51d --- /dev/null +++ b/pathways/WP2001/WP2001.svg @@ -0,0 +1,795 @@ + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + ArcPathVisio + + + + Brace + + + + Octagon + + + + Ellipse + + + + EndoplasmicReticulum + + + + HexagonPathVisio + + + + + + GolgiApparatus + + + + + + MimDegradation + + + + + Mitochondria + + + + + Octagon + + + + PentagonPathVisio + + + + + + Rectangle + + + + RoundedRectangle + + + + SarcoplasmicReticulum + + + + TrianglePathVisio + + + + none + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + MIR19B2 + + + + + + MIR92A2 + + + + + + MIR155 + + + + + + MIR20B + + + + + + MIR20A + + + + + + HIPK3 + + + + + + MIR27B + + + + + + FUSIP1 + + + + + + ELOVL5 + + + + + + MIR29C + + + + + + HIPK3 + + + + + + TGFBR2 + + + + + + CYP1B1 + + + + + + TMED10 + + + + + + HIPK3 + + + + + + HIPK3 + + + + + + + + TMEM43 + + + + + + IGF2R + + + + + + + + + MIR1-2 + + + + + + MIR1-1 + + + + + + + + + CEBPB + + + + + + FADS3 + + + + + + PHC2 + + + + + + LPL + + + + + + FADS1 + + + + + + PICALM + + + + + + + + + MIR30C2 + + + + + + MIR30C1 + + + + + + MIR30A + + + + + + MIR30B + + + + + + MIR30D + + + + + + MIR30E + + + + + + + + + PICALM + + + + + + SFRS9 + + + + + + CAP1 + + + + + + CSRP1 + + + + + + + + + MIR124-3 + + + + + + MIR124-2 + + + + + + MIR124-1 + + + + + + + + + MIR106A + + + + + + MIR106B + + + + + + + + + MIR16-1 + + + + + + MIR16-2 + + + + + Name: miR-targeted genes in adipocytes + Last Modified: 20241027162249 + Organism: Homo sapiens + + + diff --git a/pathways/WP2003/WP2003-bibliography.tsv b/pathways/WP2003/WP2003-bibliography.tsv new file mode 100644 index 000000000..6daf66eb3 --- /dev/null +++ b/pathways/WP2003/WP2003-bibliography.tsv @@ -0,0 +1,2 @@ +ID Database Citation +37986224 Pubmed "TarBase-v9.0 extends experimentally supported miRNA-gene interactions to cell-types and virally encoded miRNAs. Skoufos G, Kakoulidis P, Tastsoglou S, Zacharopoulou E, Kotsira V, Miliotis M, et al. Nucleic Acids Res. 2024 Jan 5;52(D1):D304–10. PubMed Europe PMC Scholia" diff --git a/pathways/WP2003/WP2003-datanodes.tsv b/pathways/WP2003/WP2003-datanodes.tsv new file mode 100644 index 000000000..d0680a9bb --- /dev/null +++ b/pathways/WP2003/WP2003-datanodes.tsv @@ -0,0 +1,132 @@ +Label Type Identifier Comment Ensembl NCBI gene HGNC UniProt Wikidata ChEBI InChI PubChem ChemSpider HMDB KEGG LipidMaps +RDH10 GeneProduct ensembl:ENSG00000121039 "" ensembl:ENSG00000121039 ncbigene:157506 hgnc.symbol:RDH10 uniprot:Q8IZV5;uniprot:E5RHJ9;uniprot:A0A024R7X6;uniprot:E5RK48 +TMED3 GeneProduct ensembl:ENSG00000166557 "" ensembl:ENSG00000166557 ncbigene:23423 hgnc.symbol:TMED3 uniprot:G3V1J9;uniprot:Q9Y3Q3;uniprot:F5H4M7;uniprot:A0A140VKD1 +CTSC GeneProduct ensembl:ENSG00000109861 "" ensembl:ENSG00000109861 ncbigene:1075 hgnc.symbol:CTSC uniprot:P53634;uniprot:A0A7I2V3A2;uniprot:A0A7I2V6E3;uniprot:A0A7I2V3A6;uniprot:A0A7I2V5C5;uniprot:A0A7I2YQ96;uniprot:A0A7I2V592;uniprot:A0A7I2YQT5;uniprot:A0A7I2V4Z3;uniprot:H0YCY8;uniprot:A0A7I2V2V5;uniprot:A0A7I2V466;uniprot:A0A7I2V2Q8;uniprot:A0A7I2V3M6;uniprot:A0A7I2V5L5;uniprot:A0A7I2V5J2;uniprot:A0A7I2V2F3;uniprot:H0YDA2 +DNAJB1 GeneProduct ensembl:ENSG00000132002 "" ensembl:ENSG00000132002 ncbigene:3337 hgnc.symbol:DNAJB1 uniprot:M0R1D6;uniprot:Q6FHS4;uniprot:A0A7I2YQW1;uniprot:M0QZD0;uniprot:M0R128;uniprot:A0A1B0GX60;uniprot:M0R080;uniprot:M0QYT3;uniprot:M0QXK0;uniprot:A0A7I2V3K7;uniprot:P25685 +CAPG GeneProduct ensembl:ENSG00000042493 "" ensembl:ENSG00000042493 ncbigene:822 hgnc.symbol:CAPG uniprot:E7ENU9;uniprot:P40121;uniprot:B8ZZL6;uniprot:H7C0X8;uniprot:V9HW69 +THBS1 GeneProduct ensembl:ENSG00000137801 "" ensembl:ENSG00000137801 ncbigene:7057 hgnc.symbol:THBS1 uniprot:A8MZG1;uniprot:P07996 +TNFAIP2 GeneProduct ensembl:ENSG00000185215 "" ensembl:ENSG00000185215 ncbigene:7127 hgnc.symbol:TNFAIP2 uniprot:H0YM45;uniprot:H0YKR7;uniprot:H0YKY9;uniprot:H0YKI8;uniprot:H0YL88;uniprot:Q03169;uniprot:H0YLC0 +SPTLC1 GeneProduct ensembl:ENSG00000090054 "" ensembl:ENSG00000090054 ncbigene:10558 hgnc.symbol:SPTLC1 uniprot:A0A2R8Y4S0;uniprot:A0A024R277;uniprot:A0A2R8Y6A2;uniprot:A0A2R8Y763;uniprot:O15269 +CA12 GeneProduct ensembl:ENSG00000074410 "" ensembl:ENSG00000074410 ncbigene:771 hgnc.symbol:CA12 uniprot:B3KUB4;uniprot:O43570 +GNAI2 GeneProduct ensembl:ENSG00000114353 "" ensembl:ENSG00000114353 ncbigene:2771 hgnc.symbol:GNAI2 uniprot:P04899;uniprot:F8WE78;uniprot:F8WBG4 +LMNB2 GeneProduct ensembl:ENSG00000176619 "" ensembl:ENSG00000176619 ncbigene:84823 hgnc.symbol:LMNB2 uniprot:Q03252 +CAP1 GeneProduct ensembl:ENSG00000131236 "" ensembl:ENSG00000131236 ncbigene:10487 hgnc.symbol:CAP1 uniprot:Q5T0R2;uniprot:Q5T0S3;uniprot:Q5T0R1;uniprot:Q5T0R8;uniprot:Q5T0R7;uniprot:Q5T0R9;uniprot:Q5T0R4;uniprot:Q5T0R3;uniprot:Q5T0R6;uniprot:Q01518;uniprot:Q5T0R5 +ATP6V0A1 GeneProduct ensembl:ENSG00000033627 "" ensembl:ENSG00000033627 ncbigene:535 hgnc.symbol:ATP6V0A1 uniprot:K7EN36;uniprot:K7ERA0;uniprot:K7ENA1;uniprot:K7EM24;uniprot:K7EQW2;uniprot:K7EPG4;uniprot:B7Z2A9;uniprot:K7ELZ6;uniprot:Q93050;uniprot:F5H1T6;uniprot:K7ERA6;uniprot:B7Z641 +BCL6 GeneProduct ensembl:ENSG00000113916 "" ensembl:ENSG00000113916 ncbigene:604 hgnc.symbol:BCL6 uniprot:C9JL16;uniprot:A0A0C4DH53;uniprot:P41182;uniprot:C9JCS5 +FUSIP1 GeneProduct ensembl:ENSG00000188529 "" ensembl:ENSG00000188529 ncbigene:10772 hgnc.symbol:SRSF10 uniprot:O75494;uniprot:R4GMP8;uniprot:A0A0S2Z504;uniprot:Q5JRI1;uniprot:Q6IQ42 +ANXA2 GeneProduct ensembl:ENSG00000182718 "" ensembl:ENSG00000182718 ncbigene:302 hgnc.symbol:ANXA2 uniprot:H0YNA0;uniprot:H0YKZ7;uniprot:H0YM50;uniprot:H0YMD9;uniprot:H0YNB8;uniprot:P07355;uniprot:H0YKN4;uniprot:H0YMM1;uniprot:H0YMU9;uniprot:H0YMW4;uniprot:A0A7I2V4P4;uniprot:H0YKV8;uniprot:A0A024R5Z7;uniprot:H0YKS4;uniprot:H0YKX9;uniprot:H0YL33;uniprot:H0YLV6;uniprot:H0YN42;uniprot:H0YLE2;uniprot:H0YMD0;uniprot:H0YKL9;uniprot:H0YNP5;uniprot:H0YMT9;uniprot:H0YN28 +G6PD GeneProduct ensembl:ENSG00000160211 "" ensembl:ENSG00000160211 ncbigene:2539 hgnc.symbol:G6PD uniprot:E7EM57;uniprot:P11413;uniprot:E7EUI8;uniprot:E9PD92;uniprot:A0A384NL00 +RHOG GeneProduct ensembl:ENSG00000177105 "" ensembl:ENSG00000177105 ncbigene:391 hgnc.symbol:RHOG uniprot:Q6ICQ8;uniprot:P84095 +PPP2R4 GeneProduct ensembl:ENSG00000119383 "" ensembl:ENSG00000119383 ncbigene:5524 hgnc.symbol:PTPA uniprot:Q5T949;uniprot:C9IZ76;uniprot:Q15257;uniprot:A0A804CD06;uniprot:H0Y6E5;uniprot:Q68CR8;uniprot:B7ZBP7;uniprot:H0Y562;uniprot:B7ZBP9;uniprot:A6PVN8;uniprot:B7ZBQ0;uniprot:F6WIT2;uniprot:B4DDQ6;uniprot:A6PVN5;uniprot:A6PVN6;uniprot:A6PVN7 +VPS39 GeneProduct ensembl:ENSG00000166887 "" ensembl:ENSG00000166887 ncbigene:23339 hgnc.symbol:VPS39 uniprot:Q96JC1;uniprot:H3BTU0;uniprot:A0A024R9L9 +RFT1 GeneProduct ensembl:ENSG00000163933 "" ensembl:ENSG00000163933 ncbigene:91869 hgnc.symbol:RFT1 uniprot:C9JP01;uniprot:B5MDE0;uniprot:Q96AA3 +ARID4B / Rbp1-like GeneProduct ensembl:ENSG00000054267 "" ensembl:ENSG00000054267 ncbigene:51742 hgnc.symbol:ARID4B uniprot:H7C5R6;uniprot:X6RCR8;uniprot:H0Y7Y8;uniprot:Q4LE39 +CTNNB1 GeneProduct ensembl:ENSG00000168036 "" ensembl:ENSG00000168036 ncbigene:1499 hgnc.symbol:CTNNB1 uniprot:A0A2R8Y6G0;uniprot:A0A2R8Y804;uniprot:A0A2R8Y815;uniprot:A0A2R8Y5A3;uniprot:C9IZ65;uniprot:A0A2R8Y5C3;uniprot:P35222;uniprot:A0A2R8Y7Z0;uniprot:A0A2R8YG06;uniprot:A0A2R8Y5Z1;uniprot:A0A2R8Y750;uniprot:A0A2R8YCH5;uniprot:A0A024R2Q3;uniprot:A0A2R8Y543;uniprot:B4DGU4 +PRSS21 GeneProduct ensembl:ENSG00000007038 "" ensembl:ENSG00000007038 ncbigene:10942 hgnc.symbol:PRSS21 uniprot:I3L3C7;uniprot:I3L3F7;uniprot:I3L2G7;uniprot:I3L0U2;uniprot:Q9Y6M0 +MAP3K8 GeneProduct ensembl:ENSG00000107968 "" ensembl:ENSG00000107968 ncbigene:1326 hgnc.symbol:MAP3K8 uniprot:Q5T857;uniprot:Q5T853;uniprot:Q5T854;uniprot:P41279 +USP1 GeneProduct ensembl:ENSG00000162607 "" ensembl:ENSG00000162607 ncbigene:7398 hgnc.symbol:USP1 uniprot:C9JC88;uniprot:C9JWX4;uniprot:O94782 +ADIPOR2 GeneProduct ensembl:ENSG00000006831 "" ensembl:ENSG00000006831 ncbigene:79602 hgnc.symbol:ADIPOR2 uniprot:Q86V24 +HMOX1 GeneProduct ensembl:ENSG00000100292 "" ensembl:ENSG00000100292 ncbigene:3162 hgnc.symbol:HMOX1 uniprot:A0A7I2V277;uniprot:Q6FH11;uniprot:A0A7I2V3M0;uniprot:A0A7I2YQL9;uniprot:P09601;uniprot:A0A7I2V3I1;uniprot:B1AHA8 +MLLT11 GeneProduct ensembl:ENSG00000143443 "" ensembl:ENSG00000143443 ncbigene:54964 hgnc.symbol:C1orf56 uniprot:Q9BUN1 +MRC2 GeneProduct ensembl:ENSG00000011028 "" ensembl:ENSG00000011028 ncbigene:9902 hgnc.symbol:MRC2 uniprot:J3KRF1;uniprot:J3QQZ6;uniprot:Q9UBG0;uniprot:E7EME3 +IFRD1 GeneProduct ensembl:ENSG00000006652 "" ensembl:ENSG00000006652 ncbigene:3475 hgnc.symbol:IFRD1 uniprot:E9PMY4;uniprot:C9J311;uniprot:C9JLG5;uniprot:C9J7U6;uniprot:A0A6Q8PFA5;uniprot:C9JNM6;uniprot:A4D0U1;uniprot:C9JA65;uniprot:A0A6Q8PF03;uniprot:C9JK78;uniprot:A0A6Q8PH75;uniprot:O00458;uniprot:H0YEE3;uniprot:A0A6Q8PHN0 +PRPF40A GeneProduct ensembl:ENSG00000196504 "" ensembl:ENSG00000196504 ncbigene:55660 hgnc.symbol:PRPF40A uniprot:H7C2N3;uniprot:H0YG38;uniprot:H7BXZ7;uniprot:O75400;uniprot:A0A7N4I394;uniprot:F5H578 +TH1L GeneProduct ensembl:ENSG00000101158 "" ensembl:ENSG00000101158 ncbigene:51497 hgnc.symbol:NELFCD uniprot:Q8IXH7;uniprot:X6RLT1;uniprot:H0UI80 +GOLGA7 GeneProduct ensembl:ENSG00000147533 "" ensembl:ENSG00000147533 ncbigene:51125 hgnc.symbol:GOLGA7 uniprot:Q7Z5G4 +ANAPC1 GeneProduct ensembl:ENSG00000153107 "" ensembl:ENSG00000153107 ncbigene:64682 hgnc.symbol:ANAPC1 uniprot:Q9H1A4;uniprot:A0A2R8YF63;uniprot:F8WAS1;uniprot:H0Y564 +DDX5 GeneProduct ensembl:ENSG00000108654 "" ensembl:ENSG00000108654 ncbigene:1655 hgnc.symbol:DDX5 uniprot:A0A7I2V5F5;uniprot:X6RLV5;uniprot:J3QR62;uniprot:J3KRZ1;uniprot:A0A7I2V2S0;uniprot:J3KTA4;uniprot:J3QRQ7;uniprot:J3QS79;uniprot:P17844;uniprot:J3QKN9;uniprot:J3QR02;uniprot:J3QS97;uniprot:A0A7I2V507;uniprot:A0A0G2JLI4;uniprot:J3QLG9;uniprot:J3QSF1;uniprot:J3QRN5;uniprot:K7EKV0;uniprot:J3KTQ4 +CDK6 GeneProduct ensembl:ENSG00000105810 "" ensembl:ENSG00000105810 ncbigene:1021 hgnc.symbol:CDK6 uniprot:Q00534 +BRPF3 GeneProduct ensembl:ENSG00000096070 "" ensembl:ENSG00000096070 ncbigene:27154 hgnc.symbol:BRPF3 uniprot:E9PJ12;uniprot:F6XDC4;uniprot:A8WI61;uniprot:Q9ULD4;uniprot:E9PSF3;uniprot:H0Y7B4;uniprot:E9PI60;uniprot:A8WI62;uniprot:H0Y7I6 +TPM3 GeneProduct ensembl:ENSG00000143549 "" ensembl:ENSG00000143549 ncbigene:7170 hgnc.symbol:TPM3 uniprot:A0A494C0P6;uniprot:Q5VU61;uniprot:A0A494C034;uniprot:D6R904;uniprot:J3KN67;uniprot:D6RGJ6;uniprot:P06753;uniprot:A0A0S2Z4G4;uniprot:A0A2R2Y2Q3;uniprot:A0A087WWU8;uniprot:A0A0S2Z4I4;uniprot:A0A494C0G0 +ATP6V0E GeneProduct ensembl:ENSG00000113732 "" ensembl:ENSG00000113732 ncbigene:8992 hgnc.symbol:ATP6V0E1 uniprot:O15342;uniprot:J3KN48;uniprot:E5RHL5 +ATP2A2 GeneProduct ensembl:ENSG00000174437 "" ensembl:ENSG00000174437 ncbigene:488 hgnc.symbol:ATP2A2 uniprot:A0A0C4DH86;uniprot:A0A0S2Z3L2;uniprot:H7C5W9;uniprot:P16615;uniprot:J3QSY6;uniprot:F8W1Z7 +SFXN1 GeneProduct ensembl:ENSG00000164466 "" ensembl:ENSG00000164466 ncbigene:94081 hgnc.symbol:SFXN1 uniprot:S4R2X2;uniprot:D6RFI0;uniprot:D6RDG7;uniprot:Q9H9B4;uniprot:D6RAE9;uniprot:H0Y9J5 +SLC1A4 GeneProduct ensembl:ENSG00000115902 "" ensembl:ENSG00000115902 ncbigene:6509 hgnc.symbol:SLC1A4 uniprot:P43007 +MTHFD2 GeneProduct ensembl:ENSG00000065911 "" ensembl:ENSG00000065911 ncbigene:10797 hgnc.symbol:MTHFD2 uniprot:F8WF89;uniprot:A0A7I2V2U6;uniprot:P13995;uniprot:B9A062;uniprot:F8WF06;uniprot:B8ZZU9;uniprot:A0A7I2V482;uniprot:A0A7I2V2G4;uniprot:A0A7I2V3T1;uniprot:A0A7I2YQD4 +BCL2 GeneProduct ensembl:ENSG00000171791 "" ensembl:ENSG00000171791 ncbigene:596 hgnc.symbol:BCL2 uniprot:A0A7I2V3S7;uniprot:P10415;uniprot:A0A024R2B3;uniprot:A0A024R2C4;uniprot:A0A7I2V5Q7;uniprot:A0A7I2V4W1;uniprot:A0A7I2V5Q9 +CEBPB GeneProduct ensembl:ENSG00000172216 "" ensembl:ENSG00000172216 ncbigene:1051 hgnc.symbol:CEBPB uniprot:P17676 +PPIF GeneProduct ensembl:ENSG00000108179 "" ensembl:ENSG00000108179 ncbigene:10105 hgnc.symbol:PPIF uniprot:P30405;uniprot:A0A024QZS4;uniprot:R4GN99;uniprot:H0Y548 +POM121 GeneProduct ensembl:ENSG00000135213 "" +PKM2 GeneProduct ensembl:ENSG00000067225 "" ensembl:ENSG00000067225 ncbigene:5315 hgnc.symbol:PKM uniprot:P14618;uniprot:H3BN34;uniprot:H3BUW1;uniprot:B4DNK4;uniprot:H3BQZ3;uniprot:A0A804F6T5;uniprot:H3BT25;uniprot:H3BU13;uniprot:H3BQ34;uniprot:A0A024R5Z9;uniprot:H3BTJ2;uniprot:A0A804F729;uniprot:H3BTN5;uniprot:V9HWB8 +TNFSF9 GeneProduct ensembl:ENSG00000125657 "" ensembl:ENSG00000125657 ncbigene:8744 hgnc.symbol:TNFSF9 uniprot:P41273;uniprot:A0A0U5J8I0 +FRG1 GeneProduct ensembl:ENSG00000109536 "" ensembl:ENSG00000109536 ncbigene:2483 hgnc.symbol:FRG1 uniprot:E9PI42;uniprot:E9PRR7;uniprot:E9PLY7;uniprot:Q14331;uniprot:J3KSQ7 +HNRPM GeneProduct ensembl:ENSG00000099783 "" ensembl:ENSG00000099783 ncbigene:4670 hgnc.symbol:HNRNPM uniprot:M0QYQ7;uniprot:M0R2I7;uniprot:M0QYL3;uniprot:M0QY96;uniprot:P52272;uniprot:M0R0N3;uniprot:M0R019;uniprot:M0R2T0;uniprot:A0A087X0X3;uniprot:M0QZM1;uniprot:M0R0Y6 +TYMS GeneProduct ensembl:ENSG00000176890 "" ensembl:ENSG00000176890 ncbigene:7298 hgnc.symbol:TYMS uniprot:P04818;uniprot:Q53Y97 +NP GeneProduct ensembl:ENSG00000198805 "" ensembl:ENSG00000198805 ncbigene:4860 hgnc.symbol:PNP uniprot:G3V2H3;uniprot:G3V393;uniprot:V9HWH6;uniprot:P00491;uniprot:G3V5M2 +MATR3 GeneProduct ensembl:ENSG00000015479 "" ensembl:ENSG00000015479 ncbigene:9782 hgnc.symbol:MATR3 uniprot:D6RBK5;uniprot:D6RBI2;uniprot:B3KM87;uniprot:D6REK4;uniprot:D6REM6;uniprot:P43243;uniprot:D6R991;uniprot:A0A1B0GX04;uniprot:D6RAY2;uniprot:D6RIA2;uniprot:D6RBS2;uniprot:H0Y8T4;uniprot:D6RE02;uniprot:D6R9F3 +SHOC2 GeneProduct ensembl:ENSG00000108061 "" ensembl:ENSG00000108061 ncbigene:8036 hgnc.symbol:SHOC2 uniprot:Q9UQ13;uniprot:X6RI37 +SNX6 GeneProduct ensembl:ENSG00000129515 "" ensembl:ENSG00000129515 ncbigene:58533 hgnc.symbol:SNX6 uniprot:G3V2U1;uniprot:G3V4Z5;uniprot:G3V5U2;uniprot:H0YJF8;uniprot:Q9UNH7;uniprot:G3V589;uniprot:G3V5X9;uniprot:A0A0A0MRI2 +TMEM43 GeneProduct ensembl:ENSG00000170876 "" ensembl:ENSG00000170876 ncbigene:79188 hgnc.symbol:TMEM43 uniprot:F8WDL3;uniprot:Q9BTV4;uniprot:A0A024R2F9 +MAPK14 GeneProduct ensembl:ENSG00000112062 "" ensembl:ENSG00000112062 ncbigene:1432 hgnc.symbol:MAPK14 uniprot:L7RSM2;uniprot:B5TY33;uniprot:Q16539;uniprot:B4E0K5;uniprot:E7EX54;uniprot:H7C4E2;uniprot:A0A024RD15 +YWHAQ GeneProduct ensembl:ENSG00000134308 "" ensembl:ENSG00000134308 ncbigene:10971 hgnc.symbol:YWHAQ uniprot:P27348;uniprot:E9PG15 +RAB6A GeneProduct ensembl:ENSG00000175582 "" ensembl:ENSG00000175582 ncbigene:5870 hgnc.symbol:RAB6A uniprot:A0A024R5J5;uniprot:F5H3K7;uniprot:F5GX61;uniprot:A0A024R5H8;uniprot:P20340 +TXNRD1 GeneProduct ensembl:ENSG00000198431 "" ensembl:ENSG00000198431 ncbigene:7296 hgnc.symbol:TXNRD1 uniprot:E9PKI4;uniprot:E9PLT3;uniprot:E9PQI3;uniprot:E9PKD3;uniprot:A0A0B4J225;uniprot:E9PIR7;uniprot:A0A182DWI3;uniprot:E9PIZ5;uniprot:Q16881;uniprot:E9PRI8 +RAB34 GeneProduct ensembl:ENSG00000109113 "" ensembl:ENSG00000109113 ncbigene:83871 hgnc.symbol:RAB34 uniprot:A0A024QZ68;uniprot:A0A1B0GTQ2;uniprot:V9GY61;uniprot:K7EIF2;uniprot:H7C0Y7;uniprot:E7ES60;uniprot:A0A1C7CYW6;uniprot:A0A1B0GWB1;uniprot:P0DI83;uniprot:C9JY26;uniprot:K7EJW7;uniprot:Q96PJ7;uniprot:A0A1B0GVI6;uniprot:Q9BZG1;uniprot:J3QLC6;uniprot:C9JBG0 +CDK6 GeneProduct ensembl:ENSG00000105810 "" ensembl:ENSG00000105810 ncbigene:1021 hgnc.symbol:CDK6 uniprot:Q00534 +ACP2 GeneProduct ensembl:ENSG00000134575 "" ensembl:ENSG00000134575 ncbigene:53 hgnc.symbol:ACP2 uniprot:A0A5F9ZI20;uniprot:E9PQY3;uniprot:P11117;uniprot:E9PHY0;uniprot:A0A5F9ZHR7;uniprot:B7Z7D2;uniprot:A0A5F9ZH40;uniprot:B7Z6U3;uniprot:A0A5F9ZH82 +UNC93B1 GeneProduct ensembl:ENSG00000110057 "" ensembl:ENSG00000110057 ncbigene:81622 hgnc.symbol:UNC93B1 uniprot:Q9H1C4;uniprot:E9PR93;uniprot:E9PNE5 +LPL GeneProduct ensembl:ENSG00000175445 "" ensembl:ENSG00000175445 ncbigene:4023 hgnc.symbol:LPL uniprot:A0A3B3IT60;uniprot:P06858;uniprot:E5RJZ4;uniprot:A0A1B1RVA9;uniprot:E5RHN7;uniprot:E5RJI0;uniprot:E7EW14 +PDLIM5 GeneProduct ensembl:ENSG00000163110 "" ensembl:ENSG00000163110 ncbigene:10611 hgnc.symbol:PDLIM5 uniprot:A0A0D9SFR4;uniprot:Q96HC4;uniprot:A0A0A0MSP3;uniprot:H0Y929;uniprot:H0YBI4;uniprot:A0A0D9SFW3;uniprot:D6RAA1;uniprot:H0Y8Y3;uniprot:D6RGG6 +PLXND1 GeneProduct ensembl:ENSG00000004399 "" ensembl:ENSG00000004399 ncbigene:23129 hgnc.symbol:PLXND1 uniprot:H0YA64;uniprot:D6RH25;uniprot:H0YAB2;uniprot:Q9Y4D7;uniprot:H0YAM9;uniprot:H0Y9D1 +CDIPT GeneProduct ensembl:ENSG00000103502 "" ensembl:ENSG00000103502 ncbigene:10423 hgnc.symbol:CDIPT uniprot:H3BTJ7;uniprot:H3BUR9;uniprot:O14735;uniprot:A8K3L7;uniprot:B3KY94 +CORO1C GeneProduct ensembl:ENSG00000110880 "" ensembl:ENSG00000110880 ncbigene:23603 hgnc.symbol:CORO1C uniprot:F8VRE9;uniprot:F8VSA4;uniprot:F8VTT6;uniprot:A0A024RBI5;uniprot:B4E3S0;uniprot:F8VVB7;uniprot:F8VUX3;uniprot:F8W1H8;uniprot:Q9ULV4;uniprot:F8VV53;uniprot:H0YHL7 +PPIB GeneProduct ensembl:ENSG00000166794 "" ensembl:ENSG00000166794 ncbigene:5479 hgnc.symbol:PPIB uniprot:P23284;uniprot:A0A7P0T7U3;uniprot:A0A7P0Z497;uniprot:A0A7P0TB45 +MRPL20 GeneProduct ensembl:ENSG00000242485 "" ensembl:ENSG00000242485 ncbigene:55052 hgnc.symbol:MRPL20 uniprot:Q9BYC9;uniprot:I3L2X1 +ARHGDIA GeneProduct ensembl:ENSG00000141522 "" ensembl:ENSG00000141522 ncbigene:396 hgnc.symbol:ARHGDIA uniprot:J3KS60;uniprot:J3KRE2;uniprot:J3KTF8;uniprot:J3KRY1;uniprot:J3QQX2;uniprot:V9HWE8;uniprot:P52565 +TXN2 GeneProduct ensembl:ENSG00000100348 "" ensembl:ENSG00000100348 ncbigene:25828 hgnc.symbol:TXN2 uniprot:F8WDN2;uniprot:M0QXH0;uniprot:Q99757 +SCYL1 GeneProduct ensembl:ENSG00000142186 "" ensembl:ENSG00000142186 ncbigene:57410 hgnc.symbol:SCYL1 uniprot:E9PPN3;uniprot:H0YCI6;uniprot:E9PS17;uniprot:Q96KG9;uniprot:H0YDH0;uniprot:E9PK59 +GYS1 GeneProduct ensembl:ENSG00000104812 "" ensembl:ENSG00000104812 ncbigene:2997 hgnc.symbol:GYS1 uniprot:M0QYU1;uniprot:P13807 +POLR2C GeneProduct ensembl:ENSG00000102978 "" ensembl:ENSG00000102978 ncbigene:5432 hgnc.symbol:POLR2C uniprot:H3BRR2;uniprot:P19387;uniprot:Q6FGR6 +AP3D1 GeneProduct ensembl:ENSG00000065000 "" ensembl:ENSG00000065000 ncbigene:8943 hgnc.symbol:AP3D1 uniprot:A0A2R8Y4J3;uniprot:A0A087WYN6;uniprot:K7ELX8;uniprot:A0A2R8YCY8;uniprot:O14617;uniprot:K7ERW8 +THBS1 GeneProduct ensembl:ENSG00000137801 "" ensembl:ENSG00000137801 ncbigene:7057 hgnc.symbol:THBS1 uniprot:A8MZG1;uniprot:P07996 +ZEB1 / TCF8 GeneProduct ensembl:ENSG00000148516 "" ensembl:ENSG00000148516 ncbigene:6935 hgnc.symbol:ZEB1 uniprot:F6U0D0;uniprot:P37275;uniprot:H0YMD3;uniprot:F6TDF5;uniprot:H0YND9 +SAC3D1 GeneProduct ensembl:ENSG00000168061 "" ensembl:ENSG00000168061 ncbigene:29901 hgnc.symbol:SAC3D1 uniprot:A0A6I8PRW4;uniprot:H9KVA8;uniprot:F8WC89 +ADPGK GeneProduct ensembl:ENSG00000159322 "" ensembl:ENSG00000159322 ncbigene:83440 hgnc.symbol:ADPGK uniprot:H3BRS6;uniprot:H3BUC3;uniprot:H3BU35;uniprot:H3BTH4;uniprot:Q9BRR6;uniprot:H3BN66 +FADS3 GeneProduct ensembl:ENSG00000149485 "" ensembl:ENSG00000149485 ncbigene:3992 hgnc.symbol:FADS1 uniprot:F5H2H3;uniprot:H0YB97;uniprot:F5H852;uniprot:F5H5X5;uniprot:C9JJB3;uniprot:F5H3U5;uniprot:F5H2R9;uniprot:F5H3P6;uniprot:C9J425;uniprot:F5H1Q7;uniprot:H7C2V0;uniprot:A0A0A0MR51;uniprot:F5H0Y2;uniprot:F5GWE3;uniprot:F5GYH4;uniprot:F5H8G5;uniprot:O60427 +POLE4 GeneProduct ensembl:ENSG00000115350 "" ensembl:ENSG00000115350 ncbigene:56655 hgnc.symbol:POLE4 uniprot:Q9NR33 +ANPEP GeneProduct ensembl:ENSG00000166825 "" ensembl:ENSG00000166825 ncbigene:290 hgnc.symbol:ANPEP uniprot:H0YM04;uniprot:A0A024RC61;uniprot:H0YMC1;uniprot:H0YLZ8;uniprot:H0YKT6;uniprot:P15144 +HMGA1 GeneProduct ensembl:ENSG00000137309 "" ensembl:ENSG00000137309 ncbigene:3159 hgnc.symbol:HMGA1 uniprot:A0A669KAX1;uniprot:P17096;uniprot:Q5T6U8 +SERPINE2 GeneProduct ensembl:ENSG00000135919 "" ensembl:ENSG00000135919 ncbigene:5270 hgnc.symbol:SERPINE2 uniprot:A0A024R451;uniprot:C9JN98;uniprot:C9K031;uniprot:P07093;uniprot:A0A024R498;uniprot:C9JRK5 +GAK GeneProduct ensembl:ENSG00000178950 "" ensembl:ENSG00000178950 ncbigene:2580 hgnc.symbol:GAK uniprot:D6RF16;uniprot:H0Y9M4;uniprot:D6RAW3;uniprot:H0YA39;uniprot:O14976;uniprot:D6RAQ7;uniprot:D6RE78;uniprot:H0Y8H5;uniprot:D6RC24 +GNA13 GeneProduct ensembl:ENSG00000120063 "" ensembl:ENSG00000120063 ncbigene:10672 hgnc.symbol:GNA13 uniprot:A0A024R8M0;uniprot:Q14344 +IGF2R GeneProduct ensembl:ENSG00000197081 "" ensembl:ENSG00000197081 ncbigene:3482 hgnc.symbol:IGF2R uniprot:A0A7I2YQS7;uniprot:A0A7I2V657;uniprot:A0A7I2V381;uniprot:P11717;uniprot:S4R328 +CDK5RAP3 GeneProduct ensembl:ENSG00000108465 "" ensembl:ENSG00000108465 ncbigene:80279 hgnc.symbol:CDK5RAP3 uniprot:J3QL95;uniprot:J3KRI2;uniprot:J3KRK4;uniprot:J3KSD0;uniprot:J3QS62;uniprot:J3KTA5;uniprot:J3QQY1;uniprot:J3QL86;uniprot:J3QRX0;uniprot:J3QQS7;uniprot:J3QRM1;uniprot:J3KS63;uniprot:Q96JB5 +RDH10 GeneProduct ensembl:ENSG00000121039 "" ensembl:ENSG00000121039 ncbigene:157506 hgnc.symbol:RDH10 uniprot:Q8IZV5;uniprot:E5RHJ9;uniprot:A0A024R7X6;uniprot:E5RK48 +TMEM109 GeneProduct ensembl:ENSG00000110108 "" ensembl:ENSG00000110108 ncbigene:79073 hgnc.symbol:TMEM109 uniprot:Q9BVC6 +Mcl1 GeneProduct ensembl:ENSG00000143384 "" ensembl:ENSG00000143384 ncbigene:574406;ncbigene:4170 hgnc.symbol:MCL1 uniprot:Q07820;uniprot:A0A087WT64;uniprot:A0A7I2V2W2 +SLC7A6 GeneProduct ensembl:ENSG00000103064 "" ensembl:ENSG00000103064 ncbigene:9057 hgnc.symbol:SLC7A6 uniprot:H3BUR2;uniprot:H3BSV7;uniprot:E7EPZ8;uniprot:H3BSB6;uniprot:J3QL60;uniprot:A0A024R719;uniprot:H3BPV6;uniprot:H3BRZ8;uniprot:H3BNF5;uniprot:Q92536;uniprot:H3BUA4;uniprot:H3BPK5 +KCNN4 GeneProduct ensembl:ENSG00000104783 "" ensembl:ENSG00000104783 ncbigene:3783 hgnc.symbol:KCNN4 uniprot:M0R1J0;uniprot:M0QZ70;uniprot:M0R2E8;uniprot:O15554;uniprot:M0R2F1 +TMED10 GeneProduct ensembl:ENSG00000170348 "" ensembl:ENSG00000170348 ncbigene:10972 hgnc.symbol:TMED10 uniprot:G3V2K7;uniprot:A0A024R6I3;uniprot:P49755 +WDFY1 GeneProduct ensembl:ENSG00000085449 "" ensembl:ENSG00000085449 ncbigene:57590 hgnc.symbol:WDFY1 uniprot:A0A024R488;uniprot:C9JJ54;uniprot:Q8IWB7 +tuba3 GeneProduct ensembl:ENSG00000167552 "" ensembl:ENSG00000167552 ncbigene:7846 hgnc.symbol:TUBA1A uniprot:F8VRZ4;uniprot:Q71U36;uniprot:F8W0F6;uniprot:F8VQQ4;uniprot:A0A7P0Z4A1 +WDR68 GeneProduct ensembl:ENSG00000136485 "" ensembl:ENSG00000136485 ncbigene:10238 hgnc.symbol:DCAF7 uniprot:A0A087WWI6;uniprot:P61962 +ARF4 GeneProduct ensembl:ENSG00000168374 "" ensembl:ENSG00000168374 ncbigene:378 hgnc.symbol:ARF4 uniprot:P18085;uniprot:C9JAK5;uniprot:F8WDB3;uniprot:C9J6P1;uniprot:C9JPM4;uniprot:U3KQF2 +MPDU1 GeneProduct ensembl:ENSG00000129255 "" ensembl:ENSG00000129255 ncbigene:9526 hgnc.symbol:MPDU1 uniprot:J3KSI4;uniprot:J3QRD5;uniprot:J3KTK8;uniprot:I3L1D2;uniprot:I3L4E0;uniprot:J3QQZ4;uniprot:I3L405;uniprot:J3QS48;uniprot:J3QW43;uniprot:O75352;uniprot:J3KT75;uniprot:A0A0S2Z4W8;uniprot:I3L4T1;uniprot:I3L261;uniprot:I3L295 +RTN4 GeneProduct ensembl:ENSG00000115310 "" ensembl:ENSG00000115310 ncbigene:57142 hgnc.symbol:RTN4 uniprot:C9J685;uniprot:A0A0U1RQR6;uniprot:H7C106;uniprot:Q9NQC3 +SLC7A11 GeneProduct ensembl:ENSG00000151012 "" ensembl:ENSG00000151012 ncbigene:23657 hgnc.symbol:SLC7A11 uniprot:H0Y9F9;uniprot:Q9UPY5 +PHC2 GeneProduct ensembl:ENSG00000134686 "" ensembl:ENSG00000134686 ncbigene:1912 hgnc.symbol:PHC2 uniprot:Q8IXK0;uniprot:B3KPJ4;uniprot:A0A0A0MSI2 +PISD GeneProduct ensembl:ENSG00000241878 "" ensembl:ENSG00000241878 ncbigene:23761 hgnc.symbol:PISD uniprot:A0A024R1K5;uniprot:B1AKM9;uniprot:H0Y7P7;uniprot:F8WCS6;uniprot:B1AKM6;uniprot:B1AKM8;uniprot:Q9UG56;uniprot:B1AKN0 +SH3BGRL3 GeneProduct ensembl:ENSG00000142669 "" ensembl:ENSG00000142669 ncbigene:83442 hgnc.symbol:SH3BGRL3 uniprot:Q9H299;uniprot:Q5T123 +ARCN1 GeneProduct ensembl:ENSG00000095139 "" ensembl:ENSG00000095139 ncbigene:372 hgnc.symbol:ARCN1 uniprot:P48444;uniprot:E9PK34;uniprot:B0YIW5;uniprot:B0YIW6 +CDK5RAP1 GeneProduct ensembl:ENSG00000101391 "" ensembl:ENSG00000101391 ncbigene:51654 hgnc.symbol:CDK5RAP1 uniprot:Q96SZ6;uniprot:A0A0S2Z5J9;uniprot:H0Y721;uniprot:A0A0S2Z592 +ACAA2 GeneProduct ensembl:ENSG00000167315 "" ensembl:ENSG00000167315 ncbigene:10449 hgnc.symbol:ACAA2 uniprot:K7EJ68;uniprot:A0A0B4J2A4;uniprot:K7EME0;uniprot:K7EJB1;uniprot:P42765;uniprot:K7ER88 +PTRH1 GeneProduct ensembl:ENSG00000187024 "" ensembl:ENSG00000187024 ncbigene:138428 hgnc.symbol:PTRH1 uniprot:Q86Y79;uniprot:A0A096LPA3;uniprot:C9J7Z1;uniprot:A0A286YER0;uniprot:A0A286YF52;uniprot:A0A096LP22;uniprot:A0A096LP34 +TRAM1 GeneProduct ensembl:ENSG00000067167 "" ensembl:ENSG00000067167 ncbigene:23471 hgnc.symbol:TRAM1 uniprot:Q15629;uniprot:G3XAN4;uniprot:Q6FHL3;uniprot:E5RFP8 +CHORDC1 GeneProduct ensembl:ENSG00000110172 "" ensembl:ENSG00000110172 ncbigene:26973 hgnc.symbol:CHORDC1 uniprot:Q9UHD1;uniprot:E9PL00;uniprot:E9PIF7;uniprot:E9PHZ2;uniprot:E9PIZ4;uniprot:E9PPQ5;uniprot:E9PSD5 +SNAP23 GeneProduct ensembl:ENSG00000092531 "" ensembl:ENSG00000092531 ncbigene:8773 hgnc.symbol:SNAP23 uniprot:A0A024R9R8;uniprot:A8K287;uniprot:O00161;uniprot:H3BP15;uniprot:H3BPJ0;uniprot:H3BV99;uniprot:H3BQY9;uniprot:H3BU94;uniprot:H3BM38;uniprot:H3BR99;uniprot:H3BNG6;uniprot:H3BR18;uniprot:H3BNE1 +CDCP1 GeneProduct ensembl:ENSG00000163814 "" ensembl:ENSG00000163814 ncbigene:64866 hgnc.symbol:CDCP1 uniprot:Q9H5V8 +CSRP1 GeneProduct ensembl:ENSG00000159176 "" ensembl:ENSG00000159176 ncbigene:1465 hgnc.symbol:CSRP1 uniprot:A0A087X134;uniprot:P21291;uniprot:E9PND2;uniprot:E9PP21;uniprot:E9PS42;uniprot:A0A384P5K2 +ATP6V1F GeneProduct ensembl:ENSG00000128524 "" ensembl:ENSG00000128524 ncbigene:9296 hgnc.symbol:ATP6V1F uniprot:Q16864;uniprot:A4D1K0 +ADAR GeneProduct ensembl:ENSG00000160710 "" ensembl:ENSG00000160710 ncbigene:103 hgnc.symbol:ADAR uniprot:A0A3B3ISU1;uniprot:A0A7P0Z4F9;uniprot:A0A3B3ISX1;uniprot:A0A3B3IRQ9;uniprot:A0A7P0Z4K3;uniprot:A2IBT1;uniprot:A0A3B3ITG9;uniprot:A0A7P0TA14;uniprot:P55265 +MAP2K1IP1 GeneProduct ensembl:ENSG00000109270 "" ensembl:ENSG00000109270 ncbigene:8649 hgnc.symbol:LAMTOR3 uniprot:Q9UHA4 +RAB5C GeneProduct ensembl:ENSG00000108774 "" ensembl:ENSG00000108774 ncbigene:5878 hgnc.symbol:RAB5C uniprot:P51148;uniprot:F8VWU4;uniprot:F8VSF8;uniprot:A0A024R1U4;uniprot:K7ENY4;uniprot:F8VVK3 +"TUSC2 / Fus1 , Fusion " GeneProduct ensembl:ENSG00000114383 "" ensembl:ENSG00000114383 ncbigene:11334 hgnc.symbol:TUSC2 uniprot:O75896;uniprot:F2Z2A9;uniprot:G3V0I0 +TBCA GeneProduct ensembl:ENSG00000171530 "" ensembl:ENSG00000171530 ncbigene:6902 hgnc.symbol:TBCA uniprot:E5RIW3;uniprot:E5RIX8;uniprot:A0A494C144;uniprot:E5RHG6;uniprot:E5RJD8;uniprot:E5RJM1;uniprot:O75347;uniprot:Q6FGD7 +SLC25A1 GeneProduct ensembl:ENSG00000100075 "" ensembl:ENSG00000100075 ncbigene:6576 hgnc.symbol:SLC25A1 uniprot:P53007;uniprot:B4DP62 +CD164 GeneProduct ensembl:ENSG00000135535 "" ensembl:ENSG00000135535 ncbigene:8763 hgnc.symbol:CD164 uniprot:D6R9B4;uniprot:Q04900 +IDH1 GeneProduct ensembl:ENSG00000138413 "" ensembl:ENSG00000138413 ncbigene:3417 hgnc.symbol:IDH1 uniprot:A0A024R3Y6;uniprot:C9JLU6;uniprot:O75874;uniprot:C9JJE5;uniprot:C9J4N6 +SEC24A GeneProduct ensembl:ENSG00000113615 "" ensembl:ENSG00000113615 ncbigene:10802 hgnc.symbol:SEC24A uniprot:O95486;uniprot:H0Y9J6 +FADS1 GeneProduct ensembl:ENSG00000149485 "" ensembl:ENSG00000149485 ncbigene:3992 hgnc.symbol:FADS1 uniprot:F5H2H3;uniprot:H0YB97;uniprot:F5H852;uniprot:F5H5X5;uniprot:C9JJB3;uniprot:F5H3U5;uniprot:F5H2R9;uniprot:F5H3P6;uniprot:C9J425;uniprot:F5H1Q7;uniprot:H7C2V0;uniprot:A0A0A0MR51;uniprot:F5H0Y2;uniprot:F5GWE3;uniprot:F5GYH4;uniprot:F5H8G5;uniprot:O60427 +BRWD2 GeneProduct ensembl:ENSG00000120008 "" ensembl:ENSG00000120008 ncbigene:55717 hgnc.symbol:WDR11 uniprot:S4R3P9;uniprot:Q9BZH6;uniprot:S4R451;uniprot:S4R3Z0 +FMNL2 GeneProduct ensembl:ENSG00000157827 "" ensembl:ENSG00000157827 ncbigene:114793 hgnc.symbol:FMNL2 uniprot:Q96PY5;uniprot:C9IZY8 +POM121 GeneProduct ensembl:ENSG00000196313 "" ensembl:ENSG00000196313 ncbigene:9883 hgnc.symbol:POM121 uniprot:Q96HA1 diff --git a/pathways/WP2003/WP2003.gpml b/pathways/WP2003/WP2003.gpml new file mode 100644 index 000000000..9a2d39209 --- /dev/null +++ b/pathways/WP2003/WP2003.gpml @@ -0,0 +1,998 @@ + + + This cataloge pathway was created using the database from "http://diana.cslab.ece.ntua.gr/tarbase/" with exclusions based on evidance type. This pathway only incldes miR targeted genes expressed in Leukocyte cells. This pathway is meant for data mapping. + eb9 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + 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+ + + 37986224 + PubMed + TarBase-v9.0 extends experimentally supported miRNA-gene interactions to cell-types and virally encoded miRNAs. + Nucleic Acids Res + 2024 + Skoufos G + Kakoulidis P + Tastsoglou S + Zacharopoulou E + Kotsira V + Miliotis M + Mavromati G + Grigoriadis D + Zioga M + Velli A + Koutou I + Karagkouni D + Stavropoulos S + Kardaras FS + Lifousi A + Vavalou E + Ovsepian A + Skoulakis A + Tasoulis SK + Georgakopoulos SV + Plagianakos VP + Hatzigeorgiou AG + + + leukocyte + CL:0000738 + Cell Type + + + + diff --git a/pathways/WP2003/WP2003.json b/pathways/WP2003/WP2003.json new file mode 100644 index 000000000..d5b137fb4 --- /dev/null +++ b/pathways/WP2003/WP2003.json @@ -0,0 +1,11009 @@ +{ + "entitiesById": { + "a00c2": { + "drawAs": "rect", + "fill": "#ffffff", + "fontFamily": "Arial", + "fontSize": 10, + "fontStyle": "normal", + "fontWeight": "normal", + "gpmlElementName": "DataNode", + "height": 20, + "id": "a00c2", + "isPartOf": "b26ed", + "kaavioType": 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Skoufos G, Kakoulidis P, Tastsoglou S, Zacharopoulou E, Kotsira V, Miliotis M, et al. Nucleic Acids Res. 2024 Jan 5;52(D1):D304–10. PubMed Europe PMC Scholia" diff --git a/pathways/WP2004/WP2004-datanodes.tsv b/pathways/WP2004/WP2004-datanodes.tsv new file mode 100644 index 000000000..75e23dbce --- /dev/null +++ b/pathways/WP2004/WP2004-datanodes.tsv @@ -0,0 +1,436 @@ +Label Type Identifier Comment Ensembl NCBI gene HGNC UniProt Wikidata ChEBI InChI PubChem ChemSpider HMDB KEGG LipidMaps +PHC2 GeneProduct ensembl:ENSG00000134686 "" ensembl:ENSG00000134686 ncbigene:1912 hgnc.symbol:PHC2 uniprot:Q8IXK0;uniprot:B3KPJ4;uniprot:A0A0A0MSI2 +MTHFD2 GeneProduct ensembl:ENSG00000065911 "" ensembl:ENSG00000065911 ncbigene:10797 hgnc.symbol:MTHFD2 uniprot:F8WF89;uniprot:A0A7I2V2U6;uniprot:P13995;uniprot:B9A062;uniprot:F8WF06;uniprot:B8ZZU9;uniprot:A0A7I2V482;uniprot:A0A7I2V2G4;uniprot:A0A7I2V3T1;uniprot:A0A7I2YQD4 +CHORDC1 GeneProduct ensembl:ENSG00000110172 "" ensembl:ENSG00000110172 ncbigene:26973 hgnc.symbol:CHORDC1 uniprot:Q9UHD1;uniprot:E9PL00;uniprot:E9PIF7;uniprot:E9PHZ2;uniprot:E9PIZ4;uniprot:E9PPQ5;uniprot:E9PSD5 +HOXD8 GeneProduct ensembl:ENSG00000175879 "" ensembl:ENSG00000175879 ncbigene:3234 hgnc.symbol:HOXD8 uniprot:P13378;uniprot:A0A0A0MTF4;uniprot:A0A0A0MSX5 +ARL10 GeneProduct ensembl:ENSG00000175414 "" ensembl:ENSG00000175414 ncbigene:285598 hgnc.symbol:ARL10 uniprot:H0Y9R6;uniprot:H0Y8L6;uniprot:Q8N8L6 +NP GeneProduct ensembl:ENSG00000198805 "" ensembl:ENSG00000198805 ncbigene:4860 hgnc.symbol:PNP uniprot:G3V2H3;uniprot:G3V393;uniprot:V9HWH6;uniprot:P00491;uniprot:G3V5M2 +ADPGK GeneProduct ensembl:ENSG00000159322 "" ensembl:ENSG00000159322 ncbigene:83440 hgnc.symbol:ADPGK uniprot:H3BRS6;uniprot:H3BUC3;uniprot:H3BU35;uniprot:H3BTH4;uniprot:Q9BRR6;uniprot:H3BN66 +SMAD1 GeneProduct ensembl:ENSG00000170365 "" ensembl:ENSG00000170365 ncbigene:4086 hgnc.symbol:SMAD1 uniprot:D6RAY1;uniprot:D6RD62;uniprot:D6RDN7;uniprot:A0A1D5RMR4;uniprot:D6RBH9;uniprot:Q15797;uniprot:D6REQ3 +RDH10 GeneProduct ensembl:ENSG00000121039 "" ensembl:ENSG00000121039 ncbigene:157506 hgnc.symbol:RDH10 uniprot:Q8IZV5;uniprot:E5RHJ9;uniprot:A0A024R7X6;uniprot:E5RK48 +PKM2 GeneProduct ensembl:ENSG00000067225 "" ensembl:ENSG00000067225 ncbigene:5315 hgnc.symbol:PKM uniprot:P14618;uniprot:H3BN34;uniprot:H3BUW1;uniprot:B4DNK4;uniprot:H3BQZ3;uniprot:A0A804F6T5;uniprot:H3BT25;uniprot:H3BU13;uniprot:H3BQ34;uniprot:A0A024R5Z9;uniprot:H3BTJ2;uniprot:A0A804F729;uniprot:H3BTN5;uniprot:V9HWB8 +CAPG GeneProduct ensembl:ENSG00000042493 "" ensembl:ENSG00000042493 ncbigene:822 hgnc.symbol:CAPG uniprot:E7ENU9;uniprot:P40121;uniprot:B8ZZL6;uniprot:H7C0X8;uniprot:V9HW69 +FMNL2 GeneProduct ensembl:ENSG00000157827 "" ensembl:ENSG00000157827 ncbigene:114793 hgnc.symbol:FMNL2 uniprot:Q96PY5;uniprot:C9IZY8 +EGFR GeneProduct ensembl:ENSG00000146648 "" ensembl:ENSG00000146648 ncbigene:1956 hgnc.symbol:EGFR uniprot:P00533;uniprot:Q504U8;uniprot:C9JYS6 +RFT1 GeneProduct ensembl:ENSG00000163933 "" ensembl:ENSG00000163933 ncbigene:91869 hgnc.symbol:RFT1 uniprot:C9JP01;uniprot:B5MDE0;uniprot:Q96AA3 +CDK5RAP3 GeneProduct ensembl:ENSG00000108465 "" ensembl:ENSG00000108465 ncbigene:80279 hgnc.symbol:CDK5RAP3 uniprot:J3QL95;uniprot:J3KRI2;uniprot:J3KRK4;uniprot:J3KSD0;uniprot:J3QS62;uniprot:J3KTA5;uniprot:J3QQY1;uniprot:J3QL86;uniprot:J3QRX0;uniprot:J3QQS7;uniprot:J3QRM1;uniprot:J3KS63;uniprot:Q96JB5 +EZH2 / Enx-1 GeneProduct ensembl:ENSG00000106462 "" ensembl:ENSG00000106462 ncbigene:2146 hgnc.symbol:EZH2 uniprot:A0A090N8E9;uniprot:Q15910;uniprot:A0A804HJH1;uniprot:G3XAL2;uniprot:E9PDH6;uniprot:S4S3R8;uniprot:A0A804HLB8 +MRM1 GeneProduct ensembl:ENSG00000278619 "" ensembl:ENSG00000278619 ncbigene:79922 hgnc.symbol:MRM1 uniprot:Q6IN84;uniprot:A0A087WZC1 +ELMOD2 GeneProduct ensembl:ENSG00000179387 "" ensembl:ENSG00000179387 ncbigene:255520 hgnc.symbol:ELMOD2 uniprot:Q8IZ81;uniprot:D6RJB5;uniprot:D6RBS5;uniprot:D6RHX2;uniprot:V9GY58 +TMEM43 GeneProduct ensembl:ENSG00000170876 "" ensembl:ENSG00000170876 ncbigene:79188 hgnc.symbol:TMEM43 uniprot:F8WDL3;uniprot:Q9BTV4;uniprot:A0A024R2F9 +UBE2V1 GeneProduct ensembl:ENSG00000124208 "" ensembl:ENSG00000124208 ncbigene:387522 hgnc.symbol:PEDS1-UBE2V1 uniprot:I3L0A0 +LAMC1 / laminin gamma GeneProduct ensembl:ENSG00000135862 "" ensembl:ENSG00000135862 ncbigene:3915 hgnc.symbol:LAMC1 uniprot:P11047;uniprot:R4GNC7 +GNL3L GeneProduct ensembl:ENSG00000130119 "" ensembl:ENSG00000130119 ncbigene:54552 hgnc.symbol:GNL3L uniprot:A0A6I8PL80;uniprot:A0A6I8PL58;uniprot:A0A6I8PL53;uniprot:A0A6I8PS19;uniprot:Q9NVN8;uniprot:A0A024R9Y6 +NOTCH2 GeneProduct ensembl:ENSG00000134250 "" ensembl:ENSG00000134250 ncbigene:4853 hgnc.symbol:NOTCH2 uniprot:A0A494C049;uniprot:A0A494C1U9;uniprot:A0A494C1H8;uniprot:Q04721;uniprot:A0A494C1F1;uniprot:A0A1W2PQQ5 +CORO1C GeneProduct ensembl:ENSG00000110880 "" ensembl:ENSG00000110880 ncbigene:23603 hgnc.symbol:CORO1C uniprot:F8VRE9;uniprot:F8VSA4;uniprot:F8VTT6;uniprot:A0A024RBI5;uniprot:B4E3S0;uniprot:F8VVB7;uniprot:F8VUX3;uniprot:F8W1H8;uniprot:Q9ULV4;uniprot:F8VV53;uniprot:H0YHL7 +HIPK3 GeneProduct ensembl:ENSG00000110422 "" ensembl:ENSG00000110422 ncbigene:10114 hgnc.symbol:HIPK3 uniprot:Q9H422;uniprot:E9PKD7 +ARID1A GeneProduct ensembl:ENSG00000117713 "" ensembl:ENSG00000117713 ncbigene:8289 hgnc.symbol:ARID1A uniprot:A0A1B0GVT5;uniprot:O14497;uniprot:A0A1B0GTU5;uniprot:E9PQW6;uniprot:H0YEW5;uniprot:H0Y488;uniprot:H0YCU6 +HSDL1 GeneProduct ensembl:ENSG00000103160 "" ensembl:ENSG00000103160 ncbigene:83693 hgnc.symbol:HSDL1 uniprot:H3BT52;uniprot:H3BQI7;uniprot:H3BNH5;uniprot:Q3SXM5 +TUSC2 / Fus1 , Fusion GeneProduct ensembl:ENSG00000114383 "" ensembl:ENSG00000114383 ncbigene:11334 hgnc.symbol:TUSC2 uniprot:O75896;uniprot:F2Z2A9;uniprot:G3V0I0 +DNMT3B GeneProduct ensembl:ENSG00000088305 "" ensembl:ENSG00000088305 ncbigene:1789 hgnc.symbol:DNMT3B uniprot:B4DSJ7;uniprot:Q9UBC3;uniprot:A0A2Z2CIT2;uniprot:Q2PJS8 +TYMS GeneProduct ensembl:ENSG00000176890 "" ensembl:ENSG00000176890 ncbigene:7298 hgnc.symbol:TYMS uniprot:P04818;uniprot:Q53Y97 +NM_032121 GeneProduct ensembl:ENSG00000102158 "" ensembl:ENSG00000102158 ncbigene:84061 hgnc.symbol:MAGT1 uniprot:A0A087WU53;uniprot:Q9H0U3 +tuba3 GeneProduct ensembl:ENSG00000167552 "" ensembl:ENSG00000167552 ncbigene:7846 hgnc.symbol:TUBA1A uniprot:F8VRZ4;uniprot:Q71U36;uniprot:F8W0F6;uniprot:F8VQQ4;uniprot:A0A7P0Z4A1 +PDLIM7 GeneProduct ensembl:ENSG00000196923 "" ensembl:ENSG00000196923 ncbigene:9260 hgnc.symbol:PDLIM7 uniprot:D6RH06;uniprot:D6RAN1;uniprot:H7BYK4;uniprot:D6RF83;uniprot:Q9NR12 +GPAM GeneProduct ensembl:ENSG00000119927 "" ensembl:ENSG00000119927 ncbigene:57678 hgnc.symbol:GPAM uniprot:Q9HCL2;uniprot:Q5VW52 +IFRD1 GeneProduct ensembl:ENSG00000006652 "" ensembl:ENSG00000006652 ncbigene:3475 hgnc.symbol:IFRD1 uniprot:E9PMY4;uniprot:C9J311;uniprot:C9JLG5;uniprot:C9J7U6;uniprot:A0A6Q8PFA5;uniprot:C9JNM6;uniprot:A4D0U1;uniprot:C9JA65;uniprot:A0A6Q8PF03;uniprot:C9JK78;uniprot:A0A6Q8PH75;uniprot:O00458;uniprot:H0YEE3;uniprot:A0A6Q8PHN0 +ZEB1 / TCF8 GeneProduct ensembl:ENSG00000148516 "" ensembl:ENSG00000148516 ncbigene:6935 hgnc.symbol:ZEB1 uniprot:F6U0D0;uniprot:P37275;uniprot:H0YMD3;uniprot:F6TDF5;uniprot:H0YND9 +BACE1 / Beta-Secretase 1 GeneProduct ensembl:ENSG00000186318 "" ensembl:ENSG00000186318 ncbigene:23621 hgnc.symbol:BACE1 uniprot:U3KPS1;uniprot:B7Z3Z4;uniprot:A0A7P0T924;uniprot:P56817;uniprot:Q76KP0;uniprot:B7Z3K2;uniprot:E9PJG7;uniprot:A0A024R3D5;uniprot:A0A024R3D7;uniprot:A0A024R3E8;uniprot:A0A024R3F9;uniprot:A0A7P0TAB4 +BCKDHB GeneProduct ensembl:ENSG00000083123 "" ensembl:ENSG00000083123 ncbigene:594 hgnc.symbol:BCKDHB uniprot:A0A140VKB3;uniprot:P21953 +IRS1 GeneProduct ensembl:ENSG00000169047 "" ensembl:ENSG00000169047 ncbigene:3667 hgnc.symbol:IRS1 uniprot:P35568 +MLSTD2 GeneProduct ensembl:ENSG00000197601 "" ensembl:ENSG00000197601 ncbigene:84188 hgnc.symbol:FAR1 uniprot:E9PPB8;uniprot:E9PNW8;uniprot:Q8WVX9 +POLR2C GeneProduct ensembl:ENSG00000102978 "" ensembl:ENSG00000102978 ncbigene:5432 hgnc.symbol:POLR2C uniprot:H3BRR2;uniprot:P19387;uniprot:Q6FGR6 +PDLIM5 GeneProduct ensembl:ENSG00000163110 "" ensembl:ENSG00000163110 ncbigene:10611 hgnc.symbol:PDLIM5 uniprot:A0A0D9SFR4;uniprot:Q96HC4;uniprot:A0A0A0MSP3;uniprot:H0Y929;uniprot:H0YBI4;uniprot:A0A0D9SFW3;uniprot:D6RAA1;uniprot:H0Y8Y3;uniprot:D6RGG6 +CDKN1A / p21 GeneProduct ensembl:ENSG00000124762 "" ensembl:ENSG00000124762 ncbigene:1026 hgnc.symbol:CDKN1A uniprot:A0A024RCX5;uniprot:P38936 +TPM1 GeneProduct ensembl:ENSG00000140416 "" ensembl:ENSG00000140416 ncbigene:7168 hgnc.symbol:TPM1 uniprot:A0A494BZZ2;uniprot:A0A494C0V8;uniprot:A0A0K0K1I0;uniprot:A0A0S2Z4G6;uniprot:H0YKX5;uniprot:H7BYY1;uniprot:A0A494C0I0;uniprot:B7Z596;uniprot:F5H7S3;uniprot:H0YL80;uniprot:H0YK48;uniprot:H0YKP3;uniprot:P09493;uniprot:H0YLS7;uniprot:A0A087WTJ7;uniprot:H0YL42;uniprot:A0A024R5W6;uniprot:D9YZV4;uniprot:Q6ZN40;uniprot:D9YZV5;uniprot:H0YKJ4;uniprot:D9YZV7;uniprot:H0YN06 +SUCLG2 GeneProduct ensembl:ENSG00000172340 "" ensembl:ENSG00000172340 ncbigene:8801 hgnc.symbol:SUCLG2 uniprot:Q96I99;uniprot:E9PDQ8;uniprot:H0Y852 +MAP3K8 GeneProduct ensembl:ENSG00000107968 "" ensembl:ENSG00000107968 ncbigene:1326 hgnc.symbol:MAP3K8 uniprot:Q5T857;uniprot:Q5T853;uniprot:Q5T854;uniprot:P41279 +UBE2S GeneProduct ensembl:ENSG00000108106 "" ensembl:ENSG00000108106 ncbigene:27338 hgnc.symbol:UBE2S uniprot:K7EM75;uniprot:Q16763;uniprot:K7EPJ1 +MTRR GeneProduct ensembl:ENSG00000124275 "" ensembl:ENSG00000124275 ncbigene:4552 hgnc.symbol:MTRR uniprot:D6RAY3;uniprot:D6RGC7;uniprot:H0Y8S9;uniprot:D6RAZ2;uniprot:H0Y9D5;uniprot:D6RIS8;uniprot:Q9UBK8;uniprot:H0Y963;uniprot:A0A3P9MRF3;uniprot:H0Y9Q0;uniprot:D6RF21 +MEOX2 / GAX GeneProduct ensembl:ENSG00000106511 "" ensembl:ENSG00000106511 ncbigene:4223 hgnc.symbol:MEOX2 uniprot:P50222 +EIF2C3 GeneProduct ensembl:ENSG00000126070 "" ensembl:ENSG00000126070 ncbigene:192669 hgnc.symbol:AGO3 uniprot:Q9H9G7;uniprot:A0A0U1RR19;uniprot:Q5TA56 +DNMT3A GeneProduct ensembl:ENSG00000119772 "" ensembl:ENSG00000119772 ncbigene:1788 hgnc.symbol:DNMT3A uniprot:Q9Y6K1;uniprot:F8WE91;uniprot:A0A0C4DG02 +ABCG2 GeneProduct ensembl:ENSG00000118777 "" ensembl:ENSG00000118777 ncbigene:9429 hgnc.symbol:ABCG2 uniprot:A1LUE4;uniprot:Q9UNQ0;uniprot:F8S0F2 +TMED3 GeneProduct ensembl:ENSG00000166557 "" ensembl:ENSG00000166557 ncbigene:23423 hgnc.symbol:TMED3 uniprot:G3V1J9;uniprot:Q9Y3Q3;uniprot:F5H4M7;uniprot:A0A140VKD1 +NAPG GeneProduct ensembl:ENSG00000134265 "" ensembl:ENSG00000134265 ncbigene:8774 hgnc.symbol:NAPG uniprot:J3QKW4;uniprot:Q99747;uniprot:Q6FHY4;uniprot:J3KTJ6;uniprot:J3QS28 +ELOVL5 GeneProduct ensembl:ENSG00000012660 "" ensembl:ENSG00000012660 ncbigene:60481 hgnc.symbol:ELOVL5 uniprot:A0A0A0MTI6;uniprot:Q9NYP7;uniprot:A0A024RD35 +TNFRSF10A GeneProduct ensembl:ENSG00000104689 "" ensembl:ENSG00000104689 ncbigene:8797 hgnc.symbol:TNFRSF10A uniprot:F8U8C0;uniprot:O00220;uniprot:E5RFH1 +PPP5C GeneProduct ensembl:ENSG00000011485 "" ensembl:ENSG00000011485 ncbigene:5536 hgnc.symbol:PPP5C uniprot:A8MU39;uniprot:P53041;uniprot:H0YDU8;uniprot:A0A024R0Q7 +MARS2 GeneProduct ensembl:ENSG00000247626 "" ensembl:ENSG00000247626 ncbigene:92935 hgnc.symbol:MARS2 uniprot:Q96GW9 +SLC38A1 GeneProduct ensembl:ENSG00000111371 "" ensembl:ENSG00000111371 ncbigene:81539 hgnc.symbol:SLC38A1 uniprot:Q9H2H9;uniprot:F8VX04;uniprot:F8VX12;uniprot:A0A024R124 +RCN2 GeneProduct ensembl:ENSG00000117906 "" ensembl:ENSG00000117906 ncbigene:5955 hgnc.symbol:RCN2 uniprot:H0YL43;uniprot:Q14257;uniprot:A8MXP8 +RAI14 GeneProduct ensembl:ENSG00000039560 "" ensembl:ENSG00000039560 ncbigene:26064 hgnc.symbol:RAI14 uniprot:Q9P0K7;uniprot:D6RE17;uniprot:D6REL2;uniprot:D6RDL2;uniprot:D6RBY4;uniprot:D6RF74;uniprot:D6RBW6;uniprot:D6R9G6;uniprot:D6RB27;uniprot:D6R9G4;uniprot:D6RB25 +RTN4 GeneProduct ensembl:ENSG00000115310 "" ensembl:ENSG00000115310 ncbigene:57142 hgnc.symbol:RTN4 uniprot:C9J685;uniprot:A0A0U1RQR6;uniprot:H7C106;uniprot:Q9NQC3 +MRPL20 GeneProduct ensembl:ENSG00000242485 "" ensembl:ENSG00000242485 ncbigene:55052 hgnc.symbol:MRPL20 uniprot:Q9BYC9;uniprot:I3L2X1 +RAB6A GeneProduct ensembl:ENSG00000175582 "" ensembl:ENSG00000175582 ncbigene:5870 hgnc.symbol:RAB6A uniprot:A0A024R5J5;uniprot:F5H3K7;uniprot:F5GX61;uniprot:A0A024R5H8;uniprot:P20340 +MBNL1 GeneProduct ensembl:ENSG00000152601 "" ensembl:ENSG00000152601 ncbigene:4154 hgnc.symbol:MBNL1 uniprot:H7C4Y1;uniprot:C9J7P7;uniprot:Q86VM6;uniprot:A0A0A0MQX8;uniprot:C9JP00;uniprot:H7C4T5;uniprot:C9JCX1;uniprot:C9J4T8;uniprot:Q9NR56 +FADS3 GeneProduct ensembl:ENSG00000149485 "" ensembl:ENSG00000149485 ncbigene:3992 hgnc.symbol:FADS1 uniprot:F5H2H3;uniprot:H0YB97;uniprot:F5H852;uniprot:F5H5X5;uniprot:C9JJB3;uniprot:F5H3U5;uniprot:F5H2R9;uniprot:F5H3P6;uniprot:C9J425;uniprot:F5H1Q7;uniprot:H7C2V0;uniprot:A0A0A0MR51;uniprot:F5H0Y2;uniprot:F5GWE3;uniprot:F5GYH4;uniprot:F5H8G5;uniprot:O60427 +BACE1 GeneProduct ensembl:ENSG00000186318 "" ensembl:ENSG00000186318 ncbigene:23621 hgnc.symbol:BACE1 uniprot:U3KPS1;uniprot:B7Z3Z4;uniprot:A0A7P0T924;uniprot:P56817;uniprot:Q76KP0;uniprot:B7Z3K2;uniprot:E9PJG7;uniprot:A0A024R3D5;uniprot:A0A024R3D7;uniprot:A0A024R3E8;uniprot:A0A024R3F9;uniprot:A0A7P0TAB4 +NCOA3 / AIB1 GeneProduct ensembl:ENSG00000124151 "" ensembl:ENSG00000124151 ncbigene:8202 hgnc.symbol:NCOA3 uniprot:Q9Y6Q9 +PISD GeneProduct ensembl:ENSG00000241878 "" ensembl:ENSG00000241878 ncbigene:23761 hgnc.symbol:PISD uniprot:A0A024R1K5;uniprot:B1AKM9;uniprot:H0Y7P7;uniprot:F8WCS6;uniprot:B1AKM6;uniprot:B1AKM8;uniprot:Q9UG56;uniprot:B1AKN0 +IPO4 GeneProduct ensembl:ENSG00000196497 "" ensembl:ENSG00000196497 ncbigene:79711 hgnc.symbol:IPO4 uniprot:H0YMR4;uniprot:H0YN14;uniprot:H0YLV0;uniprot:H0YKG5;uniprot:H0YK93;uniprot:H0YL92;uniprot:H0YN07;uniprot:Q8TEX9 +TMEM113 p/ ro2730 GeneProduct ensembl:ENSG00000164091 "" ensembl:ENSG00000164091 ncbigene:80335 hgnc.symbol:WDR82 uniprot:C9J355;uniprot:C9JBU3;uniprot:A0A024R333;uniprot:Q6UXN9 +PDCD4 GeneProduct ensembl:ENSG00000150593 "" ensembl:ENSG00000150593 ncbigene:27250 hgnc.symbol:PDCD4 uniprot:Q53EL6;uniprot:Q5VZS7 +CSRP1 GeneProduct ensembl:ENSG00000159176 "" ensembl:ENSG00000159176 ncbigene:1465 hgnc.symbol:CSRP1 uniprot:A0A087X134;uniprot:P21291;uniprot:E9PND2;uniprot:E9PP21;uniprot:E9PS42;uniprot:A0A384P5K2 +CYP51A1 GeneProduct ensembl:ENSG00000001630 "" ensembl:ENSG00000001630 ncbigene:1595 hgnc.symbol:CYP51A1 uniprot:H7C0D0;uniprot:Q16850 +RHOG GeneProduct ensembl:ENSG00000177105 "" ensembl:ENSG00000177105 ncbigene:391 hgnc.symbol:RHOG uniprot:Q6ICQ8;uniprot:P84095 +ATP2A2 GeneProduct ensembl:ENSG00000174437 "" ensembl:ENSG00000174437 ncbigene:488 hgnc.symbol:ATP2A2 uniprot:A0A0C4DH86;uniprot:A0A0S2Z3L2;uniprot:H7C5W9;uniprot:P16615;uniprot:J3QSY6;uniprot:F8W1Z7 +ARID4B / Rbp1-like GeneProduct ensembl:ENSG00000054267 "" ensembl:ENSG00000054267 ncbigene:51742 hgnc.symbol:ARID4B uniprot:H7C5R6;uniprot:X6RCR8;uniprot:H0Y7Y8;uniprot:Q4LE39 +RB1 GeneProduct ensembl:ENSG00000139687 "" ensembl:ENSG00000139687 ncbigene:5925 hgnc.symbol:RB1 uniprot:A0A3B3IS71;uniprot:Q92728;uniprot:A0A024RDV3;uniprot:A0A2R8YFL6;uniprot:A0A2R8Y743;uniprot:P06400 +BACH1 GeneProduct ensembl:ENSG00000156273 "" ensembl:ENSG00000156273 ncbigene:100379661;ncbigene:571 hgnc.symbol:BACH1 uniprot:C9JMP6;uniprot:F8VZL7;uniprot:H7C4B6;uniprot:C9IYH8;uniprot:M0QZP0;uniprot:O14867;uniprot:C9IYR0 +SLC7A6 GeneProduct ensembl:ENSG00000103064 "" ensembl:ENSG00000103064 ncbigene:9057 hgnc.symbol:SLC7A6 uniprot:H3BUR2;uniprot:H3BSV7;uniprot:E7EPZ8;uniprot:H3BSB6;uniprot:J3QL60;uniprot:A0A024R719;uniprot:H3BPV6;uniprot:H3BRZ8;uniprot:H3BNF5;uniprot:Q92536;uniprot:H3BUA4;uniprot:H3BPK5 +EHMT2 GeneProduct ensembl:ENSG00000204371 "" ensembl:ENSG00000204371 ncbigene:10919 hgnc.symbol:EHMT2 uniprot:H0Y4K5;uniprot:A0A024RCN9;uniprot:A2ABF9;uniprot:Q96KQ7;uniprot:A2ABF8 +AADACL1 GeneProduct ensembl:ENSG00000144959 "" ensembl:ENSG00000144959 ncbigene:57552 hgnc.symbol:NCEH1 uniprot:Q6PIU2;uniprot:A0A0A0MTJ9;uniprot:H7C046;uniprot:F8WE33 +MYLIP GeneProduct ensembl:ENSG00000007944 "" ensembl:ENSG00000007944 ncbigene:29116 hgnc.symbol:MYLIP uniprot:Q5TIA5;uniprot:Q8WY64 +E2F1 GeneProduct ensembl:ENSG00000101412 "" ensembl:ENSG00000101412 ncbigene:1869 hgnc.symbol:E2F1 uniprot:Q01094 +HNRPM GeneProduct ensembl:ENSG00000099783 "" ensembl:ENSG00000099783 ncbigene:4670 hgnc.symbol:HNRNPM uniprot:M0QYQ7;uniprot:M0R2I7;uniprot:M0QYL3;uniprot:M0QY96;uniprot:P52272;uniprot:M0R0N3;uniprot:M0R019;uniprot:M0R2T0;uniprot:A0A087X0X3;uniprot:M0QZM1;uniprot:M0R0Y6 +DHX40 GeneProduct ensembl:ENSG00000108406 "" ensembl:ENSG00000108406 ncbigene:79665 hgnc.symbol:DHX40 uniprot:J3KS08;uniprot:J3KSW6;uniprot:J3KSX9;uniprot:F5H625;uniprot:J3KTK0;uniprot:Q8IX18 +PPP2R4 GeneProduct ensembl:ENSG00000119383 "" ensembl:ENSG00000119383 ncbigene:5524 hgnc.symbol:PTPA uniprot:Q5T949;uniprot:C9IZ76;uniprot:Q15257;uniprot:A0A804CD06;uniprot:H0Y6E5;uniprot:Q68CR8;uniprot:B7ZBP7;uniprot:H0Y562;uniprot:B7ZBP9;uniprot:A6PVN8;uniprot:B7ZBQ0;uniprot:F6WIT2;uniprot:B4DDQ6;uniprot:A6PVN5;uniprot:A6PVN6;uniprot:A6PVN7 +TMED2 GeneProduct ensembl:ENSG00000086598 "" ensembl:ENSG00000086598 ncbigene:10959 hgnc.symbol:TMED2 uniprot:E7EQ72;uniprot:F5GX39;uniprot:Q15363;uniprot:Q6FHT8 +GPD2 GeneProduct ensembl:ENSG00000115159 "" ensembl:ENSG00000115159 ncbigene:2820 hgnc.symbol:GPD2 uniprot:E7EM56;uniprot:E9PDK4;uniprot:P43304;uniprot:F5GYK7 +POLA2 GeneProduct ensembl:ENSG00000014138 "" ensembl:ENSG00000014138 ncbigene:23649 hgnc.symbol:POLA2 uniprot:Q14181;uniprot:H0YDR7;uniprot:E9PIQ6;uniprot:E9PQ99 +PXDN GeneProduct ensembl:ENSG00000130508 "" ensembl:ENSG00000130508 ncbigene:7837 hgnc.symbol:PXDN uniprot:H7C1W1;uniprot:C9J4I9;uniprot:H7C300;uniprot:Q92626;uniprot:H7C3W2 +NOTCH1 GeneProduct ensembl:ENSG00000148400 "" ensembl:ENSG00000148400 ncbigene:4851 hgnc.symbol:NOTCH1 uniprot:A0A7P0TAK8;uniprot:A0A7P0TBG2;uniprot:A0A7P0T8U6;uniprot:A0A7P0T9V1;uniprot:A0A7P0TA56;uniprot:P46531;uniprot:A0A7P0TB20;uniprot:A0A7P0T8W1;uniprot:A0A7P0Z4H9 +SCYL1 GeneProduct ensembl:ENSG00000142186 "" ensembl:ENSG00000142186 ncbigene:57410 hgnc.symbol:SCYL1 uniprot:E9PPN3;uniprot:H0YCI6;uniprot:E9PS17;uniprot:Q96KG9;uniprot:H0YDH0;uniprot:E9PK59 +NXN GeneProduct ensembl:ENSG00000167693 "" ensembl:ENSG00000167693 ncbigene:64359 hgnc.symbol:NXN uniprot:Q6DKJ4;uniprot:I3L4V6;uniprot:A0A0C4DGI2 +UAP1 GeneProduct ensembl:ENSG00000117143 "" ensembl:ENSG00000117143 ncbigene:6675 hgnc.symbol:UAP1 uniprot:Q16222;uniprot:A0A140VKC0 +KRAS GeneProduct ensembl:ENSG00000133703 "" ensembl:ENSG00000133703 ncbigene:3845 hgnc.symbol:KRAS uniprot:G3V4K2;uniprot:A0A024RAV5;uniprot:P01116;uniprot:L7RSL8;uniprot:G3V5T7 +SH3BGRL3 GeneProduct ensembl:ENSG00000142669 "" ensembl:ENSG00000142669 ncbigene:83442 hgnc.symbol:SH3BGRL3 uniprot:Q9H299;uniprot:Q5T123 +VCAM1 GeneProduct ensembl:ENSG00000162692 "" ensembl:ENSG00000162692 ncbigene:7412 hgnc.symbol:VCAM1 uniprot:A0A3B3ISS8;uniprot:P19320;uniprot:E9PDD2 +SLC12A4 GeneProduct ensembl:ENSG00000124067 "" ensembl:ENSG00000124067 ncbigene:6560 hgnc.symbol:SLC12A4 uniprot:J3QKM4;uniprot:J3QRE2;uniprot:J3QSF2;uniprot:Q9UP95;uniprot:I3L1N8;uniprot:I3L4N6 +MET GeneProduct ensembl:ENSG00000105976 "" ensembl:ENSG00000105976 ncbigene:4233 hgnc.symbol:MET uniprot:A0A024R759;uniprot:P08581;uniprot:A0A024R728;uniprot:C9JKM5;uniprot:H7C130;uniprot:H7C174 +CACNA2D1 GeneProduct ensembl:ENSG00000153956 "" ensembl:ENSG00000153956 ncbigene:781 hgnc.symbol:CACNA2D1 uniprot:H0Y715;uniprot:P54289;uniprot:E7ERK3 +TERT GeneProduct ensembl:ENSG00000164362 "" ensembl:ENSG00000164362 ncbigene:7015 hgnc.symbol:TERT uniprot:A0A590UK92;uniprot:O14746 +DMTF1 GeneProduct ensembl:ENSG00000135164 "" ensembl:ENSG00000135164 ncbigene:9988 hgnc.symbol:DMTF1 uniprot:F8VXY9;uniprot:J3QLW3;uniprot:C9J8Y5;uniprot:E7EPA0;uniprot:A0A1D5RMP8;uniprot:J3KRC1;uniprot:C9JLR5;uniprot:Q9Y222;uniprot:H7C388;uniprot:C9JVQ7;uniprot:C9K0L9;uniprot:C9JED5;uniprot:C9JZZ6;uniprot:J3QKU5;uniprot:J3QLN9;uniprot:C9K0K9;uniprot:C9JFR2;uniprot:C9J4F7;uniprot:C9JGT5 +ASH2L GeneProduct ensembl:ENSG00000129691 "" ensembl:ENSG00000129691 ncbigene:9070 hgnc.symbol:ASH2L uniprot:E5RFH5;uniprot:H0YAQ0;uniprot:E5RHM1;uniprot:F5H8F7;uniprot:H0YBF6;uniprot:Q9UBL3 +RAB34 GeneProduct ensembl:ENSG00000109113 "" ensembl:ENSG00000109113 ncbigene:83871 hgnc.symbol:RAB34 uniprot:A0A024QZ68;uniprot:A0A1B0GTQ2;uniprot:V9GY61;uniprot:K7EIF2;uniprot:H7C0Y7;uniprot:E7ES60;uniprot:A0A1C7CYW6;uniprot:A0A1B0GWB1;uniprot:P0DI83;uniprot:C9JY26;uniprot:K7EJW7;uniprot:Q96PJ7;uniprot:A0A1B0GVI6;uniprot:Q9BZG1;uniprot:J3QLC6;uniprot:C9JBG0 +CCND1 / Cyclin D1 GeneProduct ensembl:ENSG00000110092 "" ensembl:ENSG00000110092 ncbigene:595 hgnc.symbol:CCND1 uniprot:P24385;uniprot:Q6FI00;uniprot:F5H437 +STRN GeneProduct ensembl:ENSG00000115808 "" ensembl:ENSG00000115808 ncbigene:6801 hgnc.symbol:STRN uniprot:O43815 +WDFY1 GeneProduct ensembl:ENSG00000085449 "" ensembl:ENSG00000085449 ncbigene:57590 hgnc.symbol:WDFY1 uniprot:A0A024R488;uniprot:C9JJ54;uniprot:Q8IWB7 +ANPEP GeneProduct ensembl:ENSG00000166825 "" ensembl:ENSG00000166825 ncbigene:290 hgnc.symbol:ANPEP uniprot:H0YM04;uniprot:A0A024RC61;uniprot:H0YMC1;uniprot:H0YLZ8;uniprot:H0YKT6;uniprot:P15144 +SLC25A24 GeneProduct ensembl:ENSG00000085491 "" ensembl:ENSG00000085491 ncbigene:29957 hgnc.symbol:SLC25A24 uniprot:H3BMI3;uniprot:J3KN42;uniprot:Q6NUK1;uniprot:A0A3B3IU96 +SLC38A2 GeneProduct ensembl:ENSG00000134294 "" ensembl:ENSG00000134294 ncbigene:54407 hgnc.symbol:SLC38A2 uniprot:A0A024R0W3;uniprot:F8VUY8;uniprot:F8VQW8;uniprot:Q96QD8 +SEC24A GeneProduct ensembl:ENSG00000113615 "" ensembl:ENSG00000113615 ncbigene:10802 hgnc.symbol:SEC24A uniprot:O95486;uniprot:H0Y9J6 +ANP32B GeneProduct ensembl:ENSG00000136938 "" ensembl:ENSG00000136938 ncbigene:10541 hgnc.symbol:ANP32B uniprot:Q92688 +PLK1 GeneProduct ensembl:ENSG00000166851 "" ensembl:ENSG00000166851 ncbigene:5347 hgnc.symbol:PLK1 uniprot:P53350;uniprot:I3L387;uniprot:I3L2H5;uniprot:I3L309 +TPM2 GeneProduct ensembl:ENSG00000198467 "" ensembl:ENSG00000198467 ncbigene:7169 hgnc.symbol:TPM2 uniprot:A7XZE4;uniprot:P07951;uniprot:U3KQK2;uniprot:Q5TCU3;uniprot:V9HW25;uniprot:A0A2R8Y6A3 +DDX5 GeneProduct ensembl:ENSG00000108654 "" ensembl:ENSG00000108654 ncbigene:1655 hgnc.symbol:DDX5 uniprot:A0A7I2V5F5;uniprot:X6RLV5;uniprot:J3QR62;uniprot:J3KRZ1;uniprot:A0A7I2V2S0;uniprot:J3KTA4;uniprot:J3QRQ7;uniprot:J3QS79;uniprot:P17844;uniprot:J3QKN9;uniprot:J3QR02;uniprot:J3QS97;uniprot:A0A7I2V507;uniprot:A0A0G2JLI4;uniprot:J3QLG9;uniprot:J3QSF1;uniprot:J3QRN5;uniprot:K7EKV0;uniprot:J3KTQ4 +ATP6V1C1 GeneProduct ensembl:ENSG00000155097 "" ensembl:ENSG00000155097 ncbigene:528 hgnc.symbol:ATP6V1C1 uniprot:P21283;uniprot:A0A024R9I0;uniprot:E7EV59 +FADS2 GeneProduct ensembl:ENSG00000134824 "" ensembl:ENSG00000134824 ncbigene:9415 hgnc.symbol:FADS2 uniprot:O95864;uniprot:E5RGD8;uniprot:E5RGZ5;uniprot:E5RHL3 +CTSC GeneProduct ensembl:ENSG00000109861 "" ensembl:ENSG00000109861 ncbigene:1075 hgnc.symbol:CTSC uniprot:P53634;uniprot:A0A7I2V3A2;uniprot:A0A7I2V6E3;uniprot:A0A7I2V3A6;uniprot:A0A7I2V5C5;uniprot:A0A7I2YQ96;uniprot:A0A7I2V592;uniprot:A0A7I2YQT5;uniprot:A0A7I2V4Z3;uniprot:H0YCY8;uniprot:A0A7I2V2V5;uniprot:A0A7I2V466;uniprot:A0A7I2V2Q8;uniprot:A0A7I2V3M6;uniprot:A0A7I2V5L5;uniprot:A0A7I2V5J2;uniprot:A0A7I2V2F3;uniprot:H0YDA2 +CDK5RAP1 GeneProduct ensembl:ENSG00000101391 "" ensembl:ENSG00000101391 ncbigene:51654 hgnc.symbol:CDK5RAP1 uniprot:Q96SZ6;uniprot:A0A0S2Z5J9;uniprot:H0Y721;uniprot:A0A0S2Z592 +VPS39 GeneProduct ensembl:ENSG00000166887 "" ensembl:ENSG00000166887 ncbigene:23339 hgnc.symbol:VPS39 uniprot:Q96JC1;uniprot:H3BTU0;uniprot:A0A024R9L9 +SMC1L1 GeneProduct ensembl:ENSG00000072501 "" ensembl:ENSG00000072501 ncbigene:8243 hgnc.symbol:SMC1A uniprot:A0A384MR33;uniprot:V9GYN9;uniprot:A0A6Q8PHC3;uniprot:Q14683;uniprot:G8JLG1;uniprot:V9GY57 +GFM1 GeneProduct ensembl:ENSG00000168827 "" ensembl:ENSG00000168827 ncbigene:85476 hgnc.symbol:GFM1 uniprot:H7C5M4;uniprot:C9JA25;uniprot:Q96RP9;uniprot:F8WAU4;uniprot:C9IZ01;uniprot:E5KND5 +GNAI2 GeneProduct ensembl:ENSG00000114353 "" ensembl:ENSG00000114353 ncbigene:2771 hgnc.symbol:GNAI2 uniprot:P04899;uniprot:F8WE78;uniprot:F8WBG4 +FNDC3B GeneProduct ensembl:ENSG00000075420 "" ensembl:ENSG00000075420 ncbigene:64778 hgnc.symbol:FNDC3B uniprot:C9JKH7;uniprot:Q53EP0 +NRP1 GeneProduct ensembl:ENSG00000099250 "" ensembl:ENSG00000099250 ncbigene:8829 hgnc.symbol:NRP1 uniprot:H0Y7Z2;uniprot:E9PEP6;uniprot:E7EX60;uniprot:H0Y4N6;uniprot:V9GYL7;uniprot:Q5JWQ2;uniprot:Q5JWQ4;uniprot:H0Y4A0;uniprot:Q5JWQ6;uniprot:Q5T7F0;uniprot:O14786 +E2F3 GeneProduct ensembl:ENSG00000112242 "" ensembl:ENSG00000112242 ncbigene:1871 hgnc.symbol:E2F3 uniprot:O00716 +HARS GeneProduct ensembl:ENSG00000170445 "" ensembl:ENSG00000170445 ncbigene:3035 hgnc.symbol:HARS1 uniprot:D6RF05;uniprot:A0A6Q8PFN6;uniprot:E7ETE2;uniprot:A0A6Q8PFF2;uniprot:P12081;uniprot:A0A6Q8PFG9;uniprot:A0A2R8YFR1;uniprot:B4DDD8;uniprot:A0A6Q8PHE3;uniprot:A0A6Q8PHA5;uniprot:B4E1C5;uniprot:A0A2R8YCI2;uniprot:A0A6Q8PF47;uniprot:A0A6Q8PHQ0;uniprot:A0A6Q8PF07 +MLLT11 GeneProduct ensembl:ENSG00000143443 "" ensembl:ENSG00000143443 ncbigene:54964 hgnc.symbol:C1orf56 uniprot:Q9BUN1 +IGF2BP1 GeneProduct ensembl:ENSG00000159217 "" ensembl:ENSG00000159217 ncbigene:10642 hgnc.symbol:IGF2BP1 uniprot:Q9NZI8 +PRIM1 GeneProduct ensembl:ENSG00000198056 "" ensembl:ENSG00000198056 ncbigene:5557 hgnc.symbol:PRIM1 uniprot:P49642;uniprot:F8VNY2;uniprot:H0YIP2;uniprot:A0A5F9ZHB6;uniprot:F8VSB2 +RCOR1 GeneProduct ensembl:ENSG00000089902 "" ensembl:ENSG00000089902 ncbigene:23186 hgnc.symbol:RCOR1 uniprot:Q9UKL0;uniprot:H0YNY4 +ARHGDIA GeneProduct ensembl:ENSG00000141522 "" ensembl:ENSG00000141522 ncbigene:396 hgnc.symbol:ARHGDIA uniprot:J3KS60;uniprot:J3KRE2;uniprot:J3KTF8;uniprot:J3KRY1;uniprot:J3QQX2;uniprot:V9HWE8;uniprot:P52565 +CDK6 GeneProduct ensembl:ENSG00000105810 "" ensembl:ENSG00000105810 ncbigene:1021 hgnc.symbol:CDK6 uniprot:Q00534 +SLC12A2 GeneProduct ensembl:ENSG00000064651 "" ensembl:ENSG00000064651 ncbigene:6558 hgnc.symbol:SLC12A2 uniprot:G3XAL9;uniprot:P55011;uniprot:Q53ZR1 +SH3BP4 GeneProduct ensembl:ENSG00000130147 "" ensembl:ENSG00000130147 ncbigene:23677 hgnc.symbol:SH3BP4 uniprot:C9JED2;uniprot:Q9P0V3;uniprot:C9JF25;uniprot:C9JRG1;uniprot:C9JWW6 +SLC25A22 GeneProduct ensembl:ENSG00000177542 "" ensembl:ENSG00000177542 ncbigene:79751 hgnc.symbol:SLC25A22 uniprot:K4DIB0;uniprot:E9PI74;uniprot:A0A0D9SG84;uniprot:K4DIB4;uniprot:K4DIA2;uniprot:K4DIB3;uniprot:E9PS95;uniprot:K4DIB8;uniprot:A0A0D9SFA8;uniprot:K4DIB6;uniprot:Q9H936;uniprot:A0A0A6YYN8;uniprot:E9PQ36;uniprot:K4DIA8;uniprot:A0A0D9SEI9;uniprot:E9PJH7;uniprot:A0A0D9SFE1;uniprot:E9PJY0 +KDELC2 GeneProduct ensembl:ENSG00000178202 "" ensembl:ENSG00000178202 ncbigene:143888 hgnc.symbol:POGLUT3 uniprot:Q7Z4H8;uniprot:H0YEM3;uniprot:A0A024R3C4 +FRG1 GeneProduct ensembl:ENSG00000109536 "" ensembl:ENSG00000109536 ncbigene:2483 hgnc.symbol:FRG1 uniprot:E9PI42;uniprot:E9PRR7;uniprot:E9PLY7;uniprot:Q14331;uniprot:J3KSQ7 +MRC2 GeneProduct ensembl:ENSG00000011028 "" ensembl:ENSG00000011028 ncbigene:9902 hgnc.symbol:MRC2 uniprot:J3KRF1;uniprot:J3QQZ6;uniprot:Q9UBG0;uniprot:E7EME3 +HMOX1 GeneProduct ensembl:ENSG00000100292 "" ensembl:ENSG00000100292 ncbigene:3162 hgnc.symbol:HMOX1 uniprot:A0A7I2V277;uniprot:Q6FH11;uniprot:A0A7I2V3M0;uniprot:A0A7I2YQL9;uniprot:P09601;uniprot:A0A7I2V3I1;uniprot:B1AHA8 +TXNRD1 GeneProduct ensembl:ENSG00000198431 "" ensembl:ENSG00000198431 ncbigene:7296 hgnc.symbol:TXNRD1 uniprot:E9PKI4;uniprot:E9PLT3;uniprot:E9PQI3;uniprot:E9PKD3;uniprot:A0A0B4J225;uniprot:E9PIR7;uniprot:A0A182DWI3;uniprot:E9PIZ5;uniprot:Q16881;uniprot:E9PRI8 +CDIPT GeneProduct ensembl:ENSG00000103502 "" ensembl:ENSG00000103502 ncbigene:10423 hgnc.symbol:CDIPT uniprot:H3BTJ7;uniprot:H3BUR9;uniprot:O14735;uniprot:A8K3L7;uniprot:B3KY94 +CBFB GeneProduct ensembl:ENSG00000067955 "" ensembl:ENSG00000067955 ncbigene:865 hgnc.symbol:CBFB uniprot:J3KRT0;uniprot:A0A024R6X2;uniprot:H3BSC0;uniprot:Q13951;uniprot:J3KS23;uniprot:A0A494C0A9;uniprot:J3KTD8 +UHRF1 GeneProduct ensembl:ENSG00000276043 "" ensembl:ENSG00000276043 ncbigene:29128 hgnc.symbol:UHRF1 uniprot:A0A087WTW0;uniprot:A0A087WWG9;uniprot:Q96T88;uniprot:A0A087WVR3 +PAFAH1B2 GeneProduct ensembl:ENSG00000168092 "" ensembl:ENSG00000168092 ncbigene:5049 hgnc.symbol:PAFAH1B2 uniprot:J3KNE3;uniprot:V9HW44;uniprot:P68402 +CUL4B GeneProduct ensembl:ENSG00000158290 "" ensembl:ENSG00000158290 ncbigene:8450 hgnc.symbol:CUL4B uniprot:A0A7P0Z4G9;uniprot:A0A7P0T9R8;uniprot:A0A7P0T9P5;uniprot:A0A669KAU9;uniprot:A0A7P0T954;uniprot:Q13620;uniprot:A0A7P0T9D0;uniprot:A0A669KAX4;uniprot:A0A7P0T809;uniprot:A0A804CL36;uniprot:K4DI93;uniprot:A0A7P0T8P8;uniprot:A0A7P0T9L3;uniprot:A0A7P0TAQ3;uniprot:A0A7P0Z4E4;uniprot:A0A7P0T9C8;uniprot:A0A7P0Z439;uniprot:A0A7P0T8W4;uniprot:A0A7P0TAF9;uniprot:A0A669KBG9;uniprot:A0A7P0T894 +GALNT7 GeneProduct ensembl:ENSG00000109586 "" ensembl:ENSG00000109586 ncbigene:51809 hgnc.symbol:GALNT7 uniprot:Q86SF2;uniprot:E9PBY3;uniprot:H0YAH3;uniprot:H0YAK0 +MTX1 GeneProduct ensembl:ENSG00000173171 "" ensembl:ENSG00000173171 ncbigene:4580 hgnc.symbol:MTX1 uniprot:Q13505;uniprot:H0Y6Y5 +TLOC1 GeneProduct ensembl:ENSG00000008952 "" ensembl:ENSG00000008952 ncbigene:7095 hgnc.symbol:SEC62 uniprot:F8WF48;uniprot:F8WCJ7;uniprot:Q99442;uniprot:F8WDG8 +SHOC2 GeneProduct ensembl:ENSG00000108061 "" ensembl:ENSG00000108061 ncbigene:8036 hgnc.symbol:SHOC2 uniprot:Q9UQ13;uniprot:X6RI37 +VAMP3 GeneProduct ensembl:ENSG00000049245 "" ensembl:ENSG00000049245 ncbigene:9341 hgnc.symbol:VAMP3 uniprot:Q15836;uniprot:Q6FGG2;uniprot:K7EKX0 +WDR68 GeneProduct ensembl:ENSG00000136485 "" ensembl:ENSG00000136485 ncbigene:10238 hgnc.symbol:DCAF7 uniprot:A0A087WWI6;uniprot:P61962 +CXCL12 GeneProduct ensembl:ENSG00000107562 "" ensembl:ENSG00000107562 ncbigene:6387 hgnc.symbol:CXCL12 uniprot:P48061 +Mcl1 GeneProduct ensembl:ENSG00000143384 "" ensembl:ENSG00000143384 ncbigene:574406;ncbigene:4170 hgnc.symbol:MCL1 uniprot:Q07820;uniprot:A0A087WT64;uniprot:A0A7I2V2W2 +BET1 GeneProduct ensembl:ENSG00000105829 "" ensembl:ENSG00000105829 ncbigene:10282 hgnc.symbol:BET1 uniprot:O15155;uniprot:Q53XK0;uniprot:A0A3B3IU16;uniprot:H7C1N3;uniprot:Q68DU7;uniprot:C9JTT8 +NRAS GeneProduct ensembl:ENSG00000009307 "" ensembl:ENSG00000009307 ncbigene:7812 hgnc.symbol:CSDE1 uniprot:E9PLT0;uniprot:A0A024R0E2;uniprot:E9PJK7;uniprot:A0A1Y8EMC9;uniprot:E9PLD4;uniprot:E9PNG3;uniprot:O75534;uniprot:A0A024R0K2;uniprot:E9PKN4 +MYO10 GeneProduct ensembl:ENSG00000145555 "" ensembl:ENSG00000145555 ncbigene:4651 hgnc.symbol:MYO10 uniprot:E9PCN3;uniprot:Q9HD67;uniprot:D6RGD1;uniprot:E9PEW5;uniprot:A0A0A0MQX1 +RQCD1 GeneProduct ensembl:ENSG00000144580 "" ensembl:ENSG00000144580 ncbigene:9125 hgnc.symbol:CNOT9 uniprot:H7C0W0;uniprot:D5MQE1;uniprot:F8WBZ6;uniprot:F8WCV7;uniprot:Q92600 +NARG1 GeneProduct ensembl:ENSG00000164134 "" ensembl:ENSG00000164134 ncbigene:80155 hgnc.symbol:NAA15 uniprot:A0A0B4J1W3;uniprot:Q9BXJ9;uniprot:D6RAP7 +THEM4 GeneProduct ensembl:ENSG00000159445 "" ensembl:ENSG00000159445 ncbigene:117145 hgnc.symbol:THEM4 uniprot:F6XC58;uniprot:E9PLJ7;uniprot:Q5T1C6 +WNT5A GeneProduct ensembl:ENSG00000114251 "" ensembl:ENSG00000114251 ncbigene:7474 hgnc.symbol:WNT5A uniprot:A0A384N611;uniprot:P41221;uniprot:A0A024R316;uniprot:C9J8I8 +SLC25A13 GeneProduct ensembl:ENSG00000004864 "" ensembl:ENSG00000004864 ncbigene:10165 hgnc.symbol:SLC25A13 uniprot:R4GN64;uniprot:Q9UJS0 +CDKN1B / KIP1, p2 GeneProduct ensembl:ENSG00000111276 "" ensembl:ENSG00000111276 ncbigene:1027 hgnc.symbol:CDKN1B uniprot:Q6I9V6;uniprot:E7ES52;uniprot:P46527;uniprot:H7C2T1 +G6PD GeneProduct ensembl:ENSG00000160211 "" ensembl:ENSG00000160211 ncbigene:2539 hgnc.symbol:G6PD uniprot:E7EM57;uniprot:P11413;uniprot:E7EUI8;uniprot:E9PD92;uniprot:A0A384NL00 +ARL2 GeneProduct ensembl:ENSG00000110025 "" ensembl:ENSG00000110025 ncbigene:29907 hgnc.symbol:SNX15 uniprot:E9PR81;uniprot:E9PMW6;uniprot:E9PNI5;uniprot:E5KQS5;uniprot:E9PK26;uniprot:Q9NRS6 +POLD2 GeneProduct ensembl:ENSG00000106628 "" ensembl:ENSG00000106628 ncbigene:5425 hgnc.symbol:POLD2 uniprot:F8W8R3;uniprot:P49005;uniprot:C9IZD2;uniprot:C9JHC7;uniprot:H7C1B3;uniprot:A0A087WWF6;uniprot:C9JLE1 +SFRS9 GeneProduct ensembl:ENSG00000111786 "" ensembl:ENSG00000111786 ncbigene:8683 hgnc.symbol:SRSF9 uniprot:S4R3G0;uniprot:H0YIB4;uniprot:Q13242 +RARS GeneProduct ensembl:ENSG00000113643 "" ensembl:ENSG00000113643 ncbigene:5917 hgnc.symbol:RARS1 uniprot:E5RJM9;uniprot:E5RI24;uniprot:E5RH09;uniprot:P54136 +DNAJB1 GeneProduct ensembl:ENSG00000132002 "" ensembl:ENSG00000132002 ncbigene:3337 hgnc.symbol:DNAJB1 uniprot:M0R1D6;uniprot:Q6FHS4;uniprot:A0A7I2YQW1;uniprot:M0QZD0;uniprot:M0R128;uniprot:A0A1B0GX60;uniprot:M0R080;uniprot:M0QYT3;uniprot:M0QXK0;uniprot:A0A7I2V3K7;uniprot:P25685 +FGF2 GeneProduct ensembl:ENSG00000138685 "" ensembl:ENSG00000138685 ncbigene:2247 hgnc.symbol:FGF2 uniprot:A0A0A0MQV6;uniprot:D9ZGF5;uniprot:P09038 +CLOCK GeneProduct ensembl:ENSG00000134852 "" ensembl:ENSG00000134852 ncbigene:9575 hgnc.symbol:CLOCK uniprot:C9JK03;uniprot:O15516 +RAD23B GeneProduct ensembl:ENSG00000119318 "" ensembl:ENSG00000119318 ncbigene:5887 hgnc.symbol:RAD23B uniprot:Q5W0S5;uniprot:Q5W0S4;uniprot:P54727;uniprot:H0Y579 +TBCA GeneProduct ensembl:ENSG00000171530 "" ensembl:ENSG00000171530 ncbigene:6902 hgnc.symbol:TBCA uniprot:E5RIW3;uniprot:E5RIX8;uniprot:A0A494C144;uniprot:E5RHG6;uniprot:E5RJD8;uniprot:E5RJM1;uniprot:O75347;uniprot:Q6FGD7 +PTPRJ GeneProduct ensembl:ENSG00000149177 "" ensembl:ENSG00000149177 ncbigene:5795 hgnc.symbol:PTPRJ uniprot:E9PJ83;uniprot:E9PPH3;uniprot:Q12913 +SAC3D1 GeneProduct ensembl:ENSG00000168061 "" ensembl:ENSG00000168061 ncbigene:29901 hgnc.symbol:SAC3D1 uniprot:A0A6I8PRW4;uniprot:H9KVA8;uniprot:F8WC89 +IGF2BP1 / IMP-1 GeneProduct ensembl:ENSG00000159217 "" ensembl:ENSG00000159217 ncbigene:10642 hgnc.symbol:IGF2BP1 uniprot:Q9NZI8 +MYCN GeneProduct ensembl:ENSG00000134323 "" ensembl:ENSG00000134323 ncbigene:4613 hgnc.symbol:MYCN uniprot:P04198;uniprot:A0A1W2PPD9 +AMIGO2 GeneProduct ensembl:ENSG00000139211 "" ensembl:ENSG00000139211 ncbigene:347902 hgnc.symbol:AMIGO2 uniprot:Q86SJ2;uniprot:A0A024R127 +TXN2 GeneProduct ensembl:ENSG00000100348 "" ensembl:ENSG00000100348 ncbigene:25828 hgnc.symbol:TXN2 uniprot:F8WDN2;uniprot:M0QXH0;uniprot:Q99757 +CALCOCO2 GeneProduct ensembl:ENSG00000136436 "" ensembl:ENSG00000136436 ncbigene:10241 hgnc.symbol:CALCOCO2 uniprot:D6RJE7;uniprot:Q13137;uniprot:D6RF70;uniprot:D6RBI4;uniprot:D6REB0;uniprot:H0YBP4;uniprot:I3L4E1;uniprot:I3L493;uniprot:H0Y9G3;uniprot:D6RBF9 +PPIF GeneProduct ensembl:ENSG00000108179 "" ensembl:ENSG00000108179 ncbigene:10105 hgnc.symbol:PPIF uniprot:P30405;uniprot:A0A024QZS4;uniprot:R4GN99;uniprot:H0Y548 +ATP6V0A1 GeneProduct ensembl:ENSG00000033627 "" ensembl:ENSG00000033627 ncbigene:535 hgnc.symbol:ATP6V0A1 uniprot:K7EN36;uniprot:K7ERA0;uniprot:K7ENA1;uniprot:K7EM24;uniprot:K7EQW2;uniprot:K7EPG4;uniprot:B7Z2A9;uniprot:K7ELZ6;uniprot:Q93050;uniprot:F5H1T6;uniprot:K7ERA6;uniprot:B7Z641 +TH1L GeneProduct ensembl:ENSG00000101158 "" ensembl:ENSG00000101158 ncbigene:51497 hgnc.symbol:NELFCD uniprot:Q8IXH7;uniprot:X6RLT1;uniprot:H0UI80 +NT5E GeneProduct ensembl:ENSG00000135318 "" ensembl:ENSG00000135318 ncbigene:4907 hgnc.symbol:NT5E uniprot:H0Y3X5;uniprot:Q96B60;uniprot:H0Y7R7;uniprot:P21589 +PTRH1 GeneProduct ensembl:ENSG00000187024 "" ensembl:ENSG00000187024 ncbigene:138428 hgnc.symbol:PTRH1 uniprot:Q86Y79;uniprot:A0A096LPA3;uniprot:C9J7Z1;uniprot:A0A286YER0;uniprot:A0A286YF52;uniprot:A0A096LP22;uniprot:A0A096LP34 +CDK6 GeneProduct ensembl:ENSG00000105810 "" ensembl:ENSG00000105810 ncbigene:1021 hgnc.symbol:CDK6 uniprot:Q00534 +ATRX GeneProduct ensembl:ENSG00000085224 "" ensembl:ENSG00000085224 ncbigene:546 hgnc.symbol:ATRX uniprot:A0A096LNW1;uniprot:P46100;uniprot:A0A096LPG6;uniprot:A0A096LNL9;uniprot:A0A6Q8PHA4;uniprot:H0Y3T0;uniprot:A0A096LNL6;uniprot:A0A096LNL7;uniprot:A0A096LNN3;uniprot:A0A096LNR8;uniprot:A0A096LP59;uniprot:A0A087WWG0;uniprot:A4LAA3;uniprot:A0A096LNX6 +AURKB GeneProduct ensembl:ENSG00000178999 "" ensembl:ENSG00000178999 ncbigene:9212 hgnc.symbol:AURKB uniprot:Q96GD4;uniprot:J3QLN8;uniprot:J3KT86;uniprot:J3KTD6;uniprot:J3QR41;uniprot:J3KRF8;uniprot:J3KRJ2 +GOLGA7 GeneProduct ensembl:ENSG00000147533 "" ensembl:ENSG00000147533 ncbigene:51125 hgnc.symbol:GOLGA7 uniprot:Q7Z5G4 +MPZL1 GeneProduct ensembl:ENSG00000197965 "" ensembl:ENSG00000197965 ncbigene:9019 hgnc.symbol:MPZL1 uniprot:F8WFC4;uniprot:A8K5D4;uniprot:A0A024R8Y3;uniprot:Q9UEL6;uniprot:O95297 +FBXW1B GeneProduct ensembl:ENSG00000072803 "" ensembl:ENSG00000072803 ncbigene:23291 hgnc.symbol:FBXW11 uniprot:E5RGC1;uniprot:E5RG78;uniprot:Q9UKB1;uniprot:E5RH92 +GFPT1 GeneProduct ensembl:ENSG00000198380 "" ensembl:ENSG00000198380 ncbigene:2673 hgnc.symbol:GFPT1 uniprot:Q06210;uniprot:A0A6I8PRT6;uniprot:A0A6I8PTT9;uniprot:A0A6I8PRN4 +AKAP8 GeneProduct ensembl:ENSG00000105127 "" ensembl:ENSG00000105127 ncbigene:10270 hgnc.symbol:AKAP8 uniprot:M0QX51;uniprot:A0A7P0TBC8;uniprot:A0A7P0TAA4;uniprot:O43823;uniprot:A0A7P0T893 +FXR2 GeneProduct ensembl:ENSG00000129245 "" ensembl:ENSG00000129245 ncbigene:9513 hgnc.symbol:FXR2 uniprot:I3L1Z2;uniprot:P51116 +SLC9A3R2 GeneProduct ensembl:ENSG00000065054 "" ensembl:ENSG00000065054 ncbigene:9351 hgnc.symbol:SLC9A3R2 uniprot:H3BUQ9;uniprot:H3BMF5;uniprot:Q15599;uniprot:H3BQS0;uniprot:H3BN50 +SYPL1 GeneProduct ensembl:ENSG00000008282 "" ensembl:ENSG00000008282 ncbigene:6856 hgnc.symbol:SYPL1 uniprot:A0A0U1RQT9;uniprot:A4D0R1;uniprot:C9JYN0;uniprot:H7C4J8;uniprot:Q16563 +AARSD1 GeneProduct ensembl:ENSG00000108825 "" ensembl:ENSG00000108825 ncbigene:100885850 hgnc.symbol:PTGES3L-AARSD1 uniprot:L7N2F6;uniprot:Q9BTE6;uniprot:B3KSP9;uniprot:H7C054;uniprot:C9J5N1;uniprot:C9JUA3 +ABHD11 GeneProduct ensembl:ENSG00000106077 "" ensembl:ENSG00000106077 ncbigene:83451 hgnc.symbol:ABHD11 uniprot:H0YC52;uniprot:C9J7Q4;uniprot:Q8NFV4;uniprot:H7C396;uniprot:H7BZ58 +NARS GeneProduct ensembl:ENSG00000134440 "" ensembl:ENSG00000134440 ncbigene:4677 hgnc.symbol:NARS1 uniprot:O43776;uniprot:K7EIU7;uniprot:K7ENF0;uniprot:K7EPK2;uniprot:K7EJ19;uniprot:K7EMQ6;uniprot:K7EQ35 +ACAA2 GeneProduct ensembl:ENSG00000167315 "" ensembl:ENSG00000167315 ncbigene:10449 hgnc.symbol:ACAA2 uniprot:K7EJ68;uniprot:A0A0B4J2A4;uniprot:K7EME0;uniprot:K7EJB1;uniprot:P42765;uniprot:K7ER88 +CDKN1C GeneProduct ensembl:ENSG00000129757 "" ensembl:ENSG00000129757 ncbigene:1028 hgnc.symbol:CDKN1C uniprot:A0A2R8YFP9;uniprot:P49918;uniprot:A6NK88 +MAPK14 GeneProduct ensembl:ENSG00000112062 "" ensembl:ENSG00000112062 ncbigene:1432 hgnc.symbol:MAPK14 uniprot:L7RSM2;uniprot:B5TY33;uniprot:Q16539;uniprot:B4E0K5;uniprot:E7EX54;uniprot:H7C4E2;uniprot:A0A024RD15 +ZEB2 / SIP1 GeneProduct ensembl:ENSG00000092208 "" ensembl:ENSG00000092208 ncbigene:8487 hgnc.symbol:GEMIN2 uniprot:H0YCF4;uniprot:O14893;uniprot:H0YDP6;uniprot:G5EA29;uniprot:S4R421;uniprot:H0YEL0;uniprot:A0A3B3IU42 +TICAM2 GeneProduct ensembl:ENSG00000134970 "" ensembl:ENSG00000134970 ncbigene:51014 hgnc.symbol:TMED7 uniprot:G3V2Y2;uniprot:Q9Y3B3 +TDG GeneProduct ensembl:ENSG00000139372 "" ensembl:ENSG00000139372 ncbigene:6996 hgnc.symbol:TDG uniprot:H0YH18;uniprot:Q13569;uniprot:F5H539;uniprot:G8JL98;uniprot:F5H0I7;uniprot:B4E127 +PSAT1 GeneProduct ensembl:ENSG00000135069 "" ensembl:ENSG00000135069 ncbigene:29968 hgnc.symbol:PSAT1 uniprot:Q9Y617;uniprot:A0A024R222;uniprot:A0A024R280 +KPNA3 GeneProduct ensembl:ENSG00000102753 "" ensembl:ENSG00000102753 ncbigene:3839 hgnc.symbol:KPNA3 uniprot:H0Y4S9;uniprot:O00505;uniprot:A0A024RDV7 +PKN2 GeneProduct ensembl:ENSG00000065243 "" ensembl:ENSG00000065243 ncbigene:5586 hgnc.symbol:PKN2 uniprot:H0Y429;uniprot:Q16513;uniprot:B1AL79;uniprot:H0Y5V5 +ARFIP1 GeneProduct ensembl:ENSG00000164144 "" ensembl:ENSG00000164144 ncbigene:27236 hgnc.symbol:ARFIP1 uniprot:B4E273;uniprot:P53367 +CYP1B1 GeneProduct ensembl:ENSG00000138061 "" ensembl:ENSG00000138061 ncbigene:1545 hgnc.symbol:CYP1B1 uniprot:A0A087WUQ7;uniprot:A0A087WW26;uniprot:Q16678 +PGM1 GeneProduct ensembl:ENSG00000079739 "" ensembl:ENSG00000079739 ncbigene:5236 hgnc.symbol:PGM1 uniprot:P36871;uniprot:A0A3B3ITK7 +TRPV6 / CAT-1 GeneProduct ensembl:ENSG00000165125 "" ensembl:ENSG00000165125 ncbigene:55503 hgnc.symbol:TRPV6 uniprot:C9J9W0;uniprot:C9JHY1;uniprot:A0A1X7SBT1;uniprot:Q9H1D0 +BRPF3 GeneProduct ensembl:ENSG00000096070 "" ensembl:ENSG00000096070 ncbigene:27154 hgnc.symbol:BRPF3 uniprot:E9PJ12;uniprot:F6XDC4;uniprot:A8WI61;uniprot:Q9ULD4;uniprot:E9PSF3;uniprot:H0Y7B4;uniprot:E9PI60;uniprot:A8WI62;uniprot:H0Y7I6 +TMEM59 GeneProduct ensembl:ENSG00000116209 "" ensembl:ENSG00000116209 ncbigene:9528 hgnc.symbol:TMEM59 uniprot:Q9BXS4;uniprot:Q5T706;uniprot:Q5T703;uniprot:Q5T704;uniprot:Q5T6Z8 +NPR3 GeneProduct ensembl:ENSG00000113389 "" ensembl:ENSG00000113389 ncbigene:4883 hgnc.symbol:NPR3 uniprot:Q60I31;uniprot:H0Y9B9;uniprot:C9JK69;uniprot:D6RDL8;uniprot:P17342 +SRPRB GeneProduct ensembl:ENSG00000144867 "" ensembl:ENSG00000144867 ncbigene:58477 hgnc.symbol:SRPRB uniprot:Q549N5;uniprot:C9J5Z8;uniprot:Q9Y5M8;uniprot:H7C4H2 +AP3D1 GeneProduct ensembl:ENSG00000065000 "" ensembl:ENSG00000065000 ncbigene:8943 hgnc.symbol:AP3D1 uniprot:A0A2R8Y4J3;uniprot:A0A087WYN6;uniprot:K7ELX8;uniprot:A0A2R8YCY8;uniprot:O14617;uniprot:K7ERW8 +KCNQ1 GeneProduct ensembl:ENSG00000053918 "" ensembl:ENSG00000053918 ncbigene:3784 hgnc.symbol:KCNQ1 uniprot:A0A2R8YDV1;uniprot:P51787;uniprot:A0A2R8YEQ9;uniprot:E9PPZ0;uniprot:F8W824 +TMEM41B GeneProduct ensembl:ENSG00000166471 "" ensembl:ENSG00000166471 ncbigene:440026 hgnc.symbol:TMEM41B uniprot:E9PJ42;uniprot:Q5BJD5 +POM121 GeneProduct ensembl:ENSG00000196313 "" ensembl:ENSG00000196313 ncbigene:9883 hgnc.symbol:POM121 uniprot:Q96HA1 +PTPRF GeneProduct ensembl:ENSG00000142949 "" ensembl:ENSG00000142949 ncbigene:5792 hgnc.symbol:PTPRF uniprot:H0Y380;uniprot:H0Y4H1;uniprot:H0Y7Z9;uniprot:A2A437;uniprot:H0Y6Z7;uniprot:P10586 +MRPS33 GeneProduct ensembl:ENSG00000090263 "" ensembl:ENSG00000090263 ncbigene:51650 hgnc.symbol:MRPS33 uniprot:A4D1T3;uniprot:C9JBY7;uniprot:Q9Y291 +ZNF622 GeneProduct ensembl:ENSG00000173545 "" ensembl:ENSG00000173545 ncbigene:90441 hgnc.symbol:ZNF622 uniprot:Q969S3 +CHD1 GeneProduct ensembl:ENSG00000153922 "" ensembl:ENSG00000153922 ncbigene:1105 hgnc.symbol:CHD1 uniprot:H0Y8Z0;uniprot:H0Y8V4;uniprot:O14646;uniprot:A0A087WVF4 +NFIA / NF1-A GeneProduct ensembl:ENSG00000162599 "" ensembl:ENSG00000162599 ncbigene:4774 hgnc.symbol:NFIA uniprot:S4R308;uniprot:A0A590UJA3;uniprot:Q12857;uniprot:S4R3K4;uniprot:S4R3K5;uniprot:A0A590UK09;uniprot:B1AKN6;uniprot:S4R3W2;uniprot:B1AKN7;uniprot:A0A590UK38;uniprot:B1AKN8;uniprot:S4R3W6;uniprot:A0A590UJU2;uniprot:A0A590UK73;uniprot:A0A590UJ82;uniprot:B1AKN5;uniprot:A0A590UJ67 +SSNA1 GeneProduct ensembl:ENSG00000176101 "" ensembl:ENSG00000176101 ncbigene:8636 hgnc.symbol:SSNA1 uniprot:O43805;uniprot:A0A024R8G6;uniprot:A0A087WV26 +MPDU1 GeneProduct ensembl:ENSG00000129255 "" ensembl:ENSG00000129255 ncbigene:9526 hgnc.symbol:MPDU1 uniprot:J3KSI4;uniprot:J3QRD5;uniprot:J3KTK8;uniprot:I3L1D2;uniprot:I3L4E0;uniprot:J3QQZ4;uniprot:I3L405;uniprot:J3QS48;uniprot:J3QW43;uniprot:O75352;uniprot:J3KT75;uniprot:A0A0S2Z4W8;uniprot:I3L4T1;uniprot:I3L261;uniprot:I3L295 +ATAD3B GeneProduct ensembl:ENSG00000160072 "" ensembl:ENSG00000160072 ncbigene:83858 hgnc.symbol:ATAD3B uniprot:A0A5K1VW56;uniprot:Q5T9A4 +POLE4 GeneProduct ensembl:ENSG00000115350 "" ensembl:ENSG00000115350 ncbigene:56655 hgnc.symbol:POLE4 uniprot:Q9NR33 +CHMP2A GeneProduct ensembl:ENSG00000130724 "" ensembl:ENSG00000130724 ncbigene:27243 hgnc.symbol:CHMP2A uniprot:M0R1T5;uniprot:O43633;uniprot:A0A024R4S0;uniprot:M0QXX8;uniprot:M0R1L7 +KCNN4 GeneProduct ensembl:ENSG00000104783 "" ensembl:ENSG00000104783 ncbigene:3783 hgnc.symbol:KCNN4 uniprot:M0R1J0;uniprot:M0QZ70;uniprot:M0R2E8;uniprot:O15554;uniprot:M0R2F1 +ZNF294 GeneProduct ensembl:ENSG00000198862 "" ensembl:ENSG00000198862 ncbigene:26046 hgnc.symbol:LTN1 uniprot:H7BYG8;uniprot:O94822;uniprot:S4R3T2 +PTMA GeneProduct ensembl:ENSG00000187514 "" ensembl:ENSG00000187514 ncbigene:5757 hgnc.symbol:PTMA uniprot:F8WCE8;uniprot:H7C2N1;uniprot:B8ZZA1;uniprot:B8ZZW7;uniprot:B8ZZQ6;uniprot:P06454;uniprot:Q53S24;uniprot:H7C031 +AP2A1 GeneProduct ensembl:ENSG00000196961 "" ensembl:ENSG00000196961 ncbigene:160 hgnc.symbol:AP2A1 uniprot:M0R2D9;uniprot:O95782 +HDAC4 GeneProduct ensembl:ENSG00000068024 "" ensembl:ENSG00000068024 ncbigene:9759 hgnc.symbol:HDAC4 uniprot:H7BZT3;uniprot:C9J481;uniprot:A0A7I2SVS4;uniprot:C9J0X4;uniprot:H7C397;uniprot:P56524 +NUCB1 GeneProduct ensembl:ENSG00000104805 "" ensembl:ENSG00000104805 ncbigene:4924 hgnc.symbol:NUCB1 uniprot:C9J3C1;uniprot:C9JBD3;uniprot:C9JKZ2;uniprot:H7BZI1;uniprot:F8WB20;uniprot:Q02818 +TMED10 GeneProduct ensembl:ENSG00000170348 "" ensembl:ENSG00000170348 ncbigene:10972 hgnc.symbol:TMED10 uniprot:G3V2K7;uniprot:A0A024R6I3;uniprot:P49755 +SLC4A7 GeneProduct ensembl:ENSG00000033867 "" ensembl:ENSG00000033867 ncbigene:9497 hgnc.symbol:SLC4A7 uniprot:A0A0A0MST8;uniprot:C9JRP1;uniprot:E9PFN4;uniprot:Q9Y6M7;uniprot:H7C3C4 +LPL GeneProduct ensembl:ENSG00000175445 "" ensembl:ENSG00000175445 ncbigene:4023 hgnc.symbol:LPL uniprot:A0A3B3IT60;uniprot:P06858;uniprot:E5RJZ4;uniprot:A0A1B1RVA9;uniprot:E5RHN7;uniprot:E5RJI0;uniprot:E7EW14 +TRIP13 GeneProduct ensembl:ENSG00000071539 "" ensembl:ENSG00000071539 ncbigene:9319 hgnc.symbol:TRIP13 uniprot:Q15645;uniprot:H0YAL2 +GNA13 GeneProduct ensembl:ENSG00000120063 "" ensembl:ENSG00000120063 ncbigene:10672 hgnc.symbol:GNA13 uniprot:A0A024R8M0;uniprot:Q14344 +KIT GeneProduct ensembl:ENSG00000157404 "" ensembl:ENSG00000157404 ncbigene:3815 hgnc.symbol:KIT uniprot:A0A0U2N547;uniprot:P10721 +SLC1A4 GeneProduct ensembl:ENSG00000115902 "" ensembl:ENSG00000115902 ncbigene:6509 hgnc.symbol:SLC1A4 uniprot:P43007 +LAMC1 GeneProduct ensembl:ENSG00000135862 "" ensembl:ENSG00000135862 ncbigene:3915 hgnc.symbol:LAMC1 uniprot:P11047;uniprot:R4GNC7 +KIAA0409 GeneProduct ensembl:ENSG00000132275 "" ensembl:ENSG00000132275 ncbigene:23378 hgnc.symbol:RRP8 uniprot:O43159;uniprot:E9PPP6;uniprot:E9PPY3;uniprot:E9PS87 +HMGA1 GeneProduct ensembl:ENSG00000137309 "" ensembl:ENSG00000137309 ncbigene:3159 hgnc.symbol:HMGA1 uniprot:A0A669KAX1;uniprot:P17096;uniprot:Q5T6U8 +NM_018211 GeneProduct ensembl:ENSG00000162437 "" ensembl:ENSG00000162437 ncbigene:55225 hgnc.symbol:RAVER2 uniprot:Q9HCJ3;uniprot:E9PE10 +PPP3R1 GeneProduct ensembl:ENSG00000221823 "" ensembl:ENSG00000221823 ncbigene:5534 hgnc.symbol:PPP3R1 uniprot:D3YTA9;uniprot:F6U1T9;uniprot:P63098 +MTPN GeneProduct ensembl:ENSG00000105887 "" ensembl:ENSG00000105887 ncbigene:136319 hgnc.symbol:MTPN uniprot:Q69YG1;uniprot:P58546;uniprot:C9JL85 +TGFBR2 GeneProduct ensembl:ENSG00000163513 "" ensembl:ENSG00000163513 ncbigene:7048 hgnc.symbol:TGFBR2 uniprot:D2JYI1;uniprot:P37173;uniprot:A3QNQ0 +ACP2 GeneProduct ensembl:ENSG00000134575 "" ensembl:ENSG00000134575 ncbigene:53 hgnc.symbol:ACP2 uniprot:A0A5F9ZI20;uniprot:E9PQY3;uniprot:P11117;uniprot:E9PHY0;uniprot:A0A5F9ZHR7;uniprot:B7Z7D2;uniprot:A0A5F9ZH40;uniprot:B7Z6U3;uniprot:A0A5F9ZH82 +ITGA2 GeneProduct ensembl:ENSG00000164171 "" ensembl:ENSG00000164171 ncbigene:3673 hgnc.symbol:ITGA2 uniprot:D6RG08;uniprot:D6R9H3;uniprot:E7ESP4;uniprot:E7EMF1;uniprot:E9PB77;uniprot:P17301 +ANXA2 GeneProduct ensembl:ENSG00000182718 "" ensembl:ENSG00000182718 ncbigene:302 hgnc.symbol:ANXA2 uniprot:H0YNA0;uniprot:H0YKZ7;uniprot:H0YM50;uniprot:H0YMD9;uniprot:H0YNB8;uniprot:P07355;uniprot:H0YKN4;uniprot:H0YMM1;uniprot:H0YMU9;uniprot:H0YMW4;uniprot:A0A7I2V4P4;uniprot:H0YKV8;uniprot:A0A024R5Z7;uniprot:H0YKS4;uniprot:H0YKX9;uniprot:H0YL33;uniprot:H0YLV6;uniprot:H0YN42;uniprot:H0YLE2;uniprot:H0YMD0;uniprot:H0YKL9;uniprot:H0YNP5;uniprot:H0YMT9;uniprot:H0YN28 +TPM3 GeneProduct ensembl:ENSG00000143549 "" ensembl:ENSG00000143549 ncbigene:7170 hgnc.symbol:TPM3 uniprot:A0A494C0P6;uniprot:Q5VU61;uniprot:A0A494C034;uniprot:D6R904;uniprot:J3KN67;uniprot:D6RGJ6;uniprot:P06753;uniprot:A0A0S2Z4G4;uniprot:A0A2R2Y2Q3;uniprot:A0A087WWU8;uniprot:A0A0S2Z4I4;uniprot:A0A494C0G0 +PPP2R5C GeneProduct ensembl:ENSG00000078304 "" ensembl:ENSG00000078304 ncbigene:5527 hgnc.symbol:PPP2R5C uniprot:G3V292;uniprot:G3V2U3;uniprot:H0YJZ3;uniprot:H0YJU0;uniprot:Q13362;uniprot:H0YJ49;uniprot:H0YK26;uniprot:H0YK25;uniprot:H0YN58;uniprot:H0YJ12;uniprot:H0YN84;uniprot:H0YJ35;uniprot:H0YNJ3;uniprot:G3V5T2;uniprot:Q96B13;uniprot:H0YNR8 +TNFSF9 GeneProduct ensembl:ENSG00000125657 "" ensembl:ENSG00000125657 ncbigene:8744 hgnc.symbol:TNFSF9 uniprot:P41273;uniprot:A0A0U5J8I0 +EHMT1 GeneProduct ensembl:ENSG00000181090 "" ensembl:ENSG00000181090 ncbigene:79813 hgnc.symbol:EHMT1 uniprot:A0A0D9SEP2;uniprot:A0A0D9SFS4;uniprot:A0A1B0GU48;uniprot:A0A1B0GW79;uniprot:A0A0D9SEQ1;uniprot:A0A1B0GTP4;uniprot:A0A1B0GW12;uniprot:A0A0D9SER3;uniprot:A0A1B0GV89;uniprot:A0A1W2PPZ7;uniprot:A0A1B0GVZ8;uniprot:A0A0C4DGF8;uniprot:A0A0D9SFX4;uniprot:Q9H9B1;uniprot:A0A1B0GUD1;uniprot:A0A0D9SEY2;uniprot:A0A1B0GV09;uniprot:A0A0D9SFD7;uniprot:A0A0D9SFG7;uniprot:A0A1B0GWF6;uniprot:A0A0D9SFM6;uniprot:A0A0D9SF38;uniprot:A0A0D9SER9 +HOXA5 GeneProduct ensembl:ENSG00000106004 "" ensembl:ENSG00000106004 ncbigene:3202 hgnc.symbol:HOXA5 uniprot:P20719 +SLC25A32 GeneProduct ensembl:ENSG00000164933 "" ensembl:ENSG00000164933 ncbigene:81034 hgnc.symbol:SLC25A32 uniprot:E5RFL3;uniprot:E5RGT9;uniprot:E5RGK5;uniprot:Q9H2D1 +PLAG1 GeneProduct ensembl:ENSG00000181690 "" ensembl:ENSG00000181690 ncbigene:5324 hgnc.symbol:PLAG1 uniprot:A0A024R7Z0;uniprot:Q6DJT9 +RHOB GeneProduct ensembl:ENSG00000143878 "" ensembl:ENSG00000143878 ncbigene:388 hgnc.symbol:RHOB uniprot:P62745 +RAB27B GeneProduct ensembl:ENSG00000041353 "" ensembl:ENSG00000041353 ncbigene:5874 hgnc.symbol:RAB27B uniprot:K7EJ38;uniprot:K7ES41;uniprot:O00194 +RAB5C GeneProduct ensembl:ENSG00000108774 "" ensembl:ENSG00000108774 ncbigene:5878 hgnc.symbol:RAB5C uniprot:P51148;uniprot:F8VWU4;uniprot:F8VSF8;uniprot:A0A024R1U4;uniprot:K7ENY4;uniprot:F8VVK3 +CDKN2A / INK4a , p16 GeneProduct ensembl:ENSG00000147889 "" ensembl:ENSG00000147889 ncbigene:1029 hgnc.symbol:CDKN2A uniprot:K7ENC6;uniprot:K7ES20;uniprot:J3QRG6;uniprot:Q8N726;uniprot:P42771;uniprot:K7PML8 +TPM4 GeneProduct ensembl:ENSG00000167460 "" ensembl:ENSG00000167460 ncbigene:7171 hgnc.symbol:TPM4 uniprot:A0A2R8YH90;uniprot:K7ERG3;uniprot:A0A2R8YGX3;uniprot:A0A5F9UKJ4;uniprot:A0A590UJB9;uniprot:A0A590UKD0;uniprot:A0A5F9UN72;uniprot:A0A2R8YEU4;uniprot:V9HW56;uniprot:A0A2R8YE05;uniprot:K7ENT6;uniprot:A0A590UK79;uniprot:P67936;uniprot:K7ELP0;uniprot:A0A2R8YHD2;uniprot:K7EPB9;uniprot:A0A2R8Y5V9 +C1QBP GeneProduct ensembl:ENSG00000108561 "" ensembl:ENSG00000108561 ncbigene:708 hgnc.symbol:C1QBP uniprot:I3L3Q7;uniprot:I3L3B0;uniprot:A0A0G2JLC0;uniprot:Q07021 +LY6K GeneProduct ensembl:ENSG00000160886 "" ensembl:ENSG00000160886 ncbigene:54742 hgnc.symbol:LY6K uniprot:E5RGJ8;uniprot:H0YB07;uniprot:Q17RY6 +CGI-38 GeneProduct ensembl:ENSG00000159713 "" ensembl:ENSG00000159713 ncbigene:51673 hgnc.symbol:TPPP3 uniprot:Q9BW30;uniprot:A0A024R702 +PURA GeneProduct ensembl:ENSG00000185129 "" ensembl:ENSG00000185129 ncbigene:5813 hgnc.symbol:PURA uniprot:A0A494C0X8;uniprot:Q00577;uniprot:A0A494C0H6 +SDCBP GeneProduct ensembl:ENSG00000137575 "" ensembl:ENSG00000137575 ncbigene:6386 hgnc.symbol:SDCBP uniprot:B4DHN5;uniprot:O00560;uniprot:G5EA09;uniprot:A0A024R7Z5;uniprot:E9PBU7 +GYS1 GeneProduct ensembl:ENSG00000104812 "" ensembl:ENSG00000104812 ncbigene:2997 hgnc.symbol:GYS1 uniprot:M0QYU1;uniprot:P13807 +MAP2K1IP1 GeneProduct ensembl:ENSG00000109270 "" ensembl:ENSG00000109270 ncbigene:8649 hgnc.symbol:LAMTOR3 uniprot:Q9UHA4 +ATG9A GeneProduct ensembl:ENSG00000198925 "" ensembl:ENSG00000198925 ncbigene:79065 hgnc.symbol:ATG9A uniprot:C9JFV2;uniprot:C9JS65;uniprot:F2Z3I6;uniprot:C9JD65;uniprot:C9JXG2;uniprot:C9JDK4;uniprot:C9JX27;uniprot:C9IYZ9;uniprot:C9JKV7;uniprot:H7C1G6;uniprot:Q7Z3C6;uniprot:A0A024R438 +BRWD2 GeneProduct ensembl:ENSG00000120008 "" ensembl:ENSG00000120008 ncbigene:55717 hgnc.symbol:WDR11 uniprot:S4R3P9;uniprot:Q9BZH6;uniprot:S4R451;uniprot:S4R3Z0 +CD164 GeneProduct ensembl:ENSG00000135535 "" ensembl:ENSG00000135535 ncbigene:8763 hgnc.symbol:CD164 uniprot:D6R9B4;uniprot:Q04900 +TM6SF1 GeneProduct ensembl:ENSG00000136404 "" ensembl:ENSG00000136404 ncbigene:53346 hgnc.symbol:TM6SF1 uniprot:E9PD04;uniprot:Q6P4D7;uniprot:Q8N5N8;uniprot:Q9BZW5;uniprot:H3BMK0;uniprot:H3BM84 +PLXND1 GeneProduct ensembl:ENSG00000004399 "" ensembl:ENSG00000004399 ncbigene:23129 hgnc.symbol:PLXND1 uniprot:H0YA64;uniprot:D6RH25;uniprot:H0YAB2;uniprot:Q9Y4D7;uniprot:H0YAM9;uniprot:H0Y9D1 +AXL GeneProduct ensembl:ENSG00000167601 "" ensembl:ENSG00000167601 ncbigene:558 hgnc.symbol:AXL uniprot:M0R0W6;uniprot:P30530 +PPP3CA GeneProduct ensembl:ENSG00000138814 "" ensembl:ENSG00000138814 ncbigene:5530 hgnc.symbol:PPP3CA uniprot:E9PPC8;uniprot:A0A0S2Z4B5;uniprot:A0A0S2Z4C6;uniprot:E7ETC2;uniprot:E9PK68;uniprot:Q08209;uniprot:H0YAB4 +MSI2 GeneProduct ensembl:ENSG00000153944 "" ensembl:ENSG00000153944 ncbigene:124540 hgnc.symbol:MSI2 uniprot:A0A6Q8PFI2;uniprot:J3KTC1;uniprot:A0A6Q8PGF5;uniprot:Q96DH6;uniprot:J3QKT5;uniprot:A0A6Q8PGD8;uniprot:A0A6Q8PH41;uniprot:A0A6Q8PH51;uniprot:B4DHE8;uniprot:A0A6Q8PFU8;uniprot:A0A6Q8PHP1;uniprot:B4DM51;uniprot:A0A6Q8PHT3;uniprot:A0A6Q8PH26;uniprot:A0A6Q8PF05 +DHX15 GeneProduct ensembl:ENSG00000109606 "" ensembl:ENSG00000109606 ncbigene:1665 hgnc.symbol:DHX15 uniprot:O43143 +ATG3 GeneProduct ensembl:ENSG00000144848 "" ensembl:ENSG00000144848 ncbigene:64422 hgnc.symbol:ATG3 uniprot:F8WDI0;uniprot:C9JNW8;uniprot:Q9NT62 +LUZP1 GeneProduct ensembl:ENSG00000169641 "" ensembl:ENSG00000169641 ncbigene:7798 hgnc.symbol:LUZP1 uniprot:Q86V48;uniprot:E5RFK8;uniprot:E5RHU7 +PDE3A GeneProduct ensembl:ENSG00000172572 "" ensembl:ENSG00000172572 ncbigene:5139 hgnc.symbol:PDE3A uniprot:Q14432 +SNAP29 GeneProduct ensembl:ENSG00000099940 "" ensembl:ENSG00000099940 ncbigene:9342 hgnc.symbol:SNAP29 uniprot:C9JAF7;uniprot:O95721 +PICALM GeneProduct ensembl:ENSG00000073921 "" ensembl:ENSG00000073921 ncbigene:8301 hgnc.symbol:PICALM uniprot:E9PJT1;uniprot:H0YCY1;uniprot:A0A024R5L7;uniprot:E9PI56;uniprot:E9PK13;uniprot:H0YD48;uniprot:H0YE97;uniprot:Q13492;uniprot:E9PKP6;uniprot:H0YEY8;uniprot:H0YEH1;uniprot:E9PLJ8;uniprot:H0YEF7;uniprot:A0A024R5P1 +SYNE1 GeneProduct ensembl:ENSG00000131018 "" ensembl:ENSG00000131018 ncbigene:23345 hgnc.symbol:SYNE1 uniprot:A0A5F9ZHB2;uniprot:Q8NF91;uniprot:A0A5F9ZHD7;uniprot:F5GXQ8;uniprot:F5GYQ7;uniprot:F5H422;uniprot:I6XKI8;uniprot:H0YFT4;uniprot:F5H4Q0;uniprot:F5GZ83;uniprot:F8WAI0;uniprot:A0A5F9ZI52;uniprot:A0A5F9ZHR3;uniprot:F5H6R8;uniprot:B7Z9Y6;uniprot:Q5JV20;uniprot:A0A5F9ZHE1;uniprot:A0A5F9ZHI3;uniprot:A0A5F9ZH87;uniprot:A0A5F9ZH00;uniprot:A0A0C4DH48;uniprot:A0A5F9ZH86;uniprot:H0Y326;uniprot:A0A0C4DG40;uniprot:H0Y325;uniprot:H0YGD3 +ABHD10 GeneProduct ensembl:ENSG00000144827 "" ensembl:ENSG00000144827 ncbigene:55347 hgnc.symbol:ABHD10 uniprot:F8WBQ6;uniprot:F8WBJ5;uniprot:Q9NUJ1 +GNPNAT1 GeneProduct ensembl:ENSG00000100522 "" ensembl:ENSG00000100522 ncbigene:64841 hgnc.symbol:GNPNAT1 uniprot:A0A024R649;uniprot:G3V4W4;uniprot:G3V5E4;uniprot:Q96EK6 +BCL2 GeneProduct ensembl:ENSG00000171791 "" ensembl:ENSG00000171791 ncbigene:596 hgnc.symbol:BCL2 uniprot:A0A7I2V3S7;uniprot:P10415;uniprot:A0A024R2B3;uniprot:A0A024R2C4;uniprot:A0A7I2V5Q7;uniprot:A0A7I2V4W1;uniprot:A0A7I2V5Q9 +GAS2L1 GeneProduct ensembl:ENSG00000185340 "" ensembl:ENSG00000185340 ncbigene:10634 hgnc.symbol:GAS2L1 uniprot:A0A5E8;uniprot:C9JFI0;uniprot:A0A384P5D0;uniprot:C9JRR6;uniprot:Q99501 +GRPEL2 GeneProduct ensembl:ENSG00000164284 "" ensembl:ENSG00000164284 ncbigene:134266 hgnc.symbol:GRPEL2 uniprot:Q8TAA5;uniprot:D6RGI6 +CPOX GeneProduct ensembl:ENSG00000080819 "" ensembl:ENSG00000080819 ncbigene:1371 hgnc.symbol:CPOX uniprot:D6RER6;uniprot:P36551 +EIF4E GeneProduct ensembl:ENSG00000151247 "" ensembl:ENSG00000151247 ncbigene:1977 hgnc.symbol:EIF4E uniprot:D6RBW1;uniprot:D6RFJ3;uniprot:X5D7E3;uniprot:P06730;uniprot:H0Y8J7 +TRMT1 GeneProduct ensembl:ENSG00000104907 "" ensembl:ENSG00000104907 ncbigene:55621 hgnc.symbol:TRMT1 uniprot:Q9NXH9;uniprot:K7ENI9;uniprot:K7EQY6;uniprot:K7EJX9;uniprot:A0A024R7I5;uniprot:K7EQQ8;uniprot:K7EMZ2;uniprot:K7ERR5;uniprot:K7EQU7 +UBE4A GeneProduct ensembl:ENSG00000110344 "" ensembl:ENSG00000110344 ncbigene:9354 hgnc.symbol:UBE4A uniprot:B7Z7P0;uniprot:Q14139 +SNAP23 GeneProduct ensembl:ENSG00000092531 "" ensembl:ENSG00000092531 ncbigene:8773 hgnc.symbol:SNAP23 uniprot:A0A024R9R8;uniprot:A8K287;uniprot:O00161;uniprot:H3BP15;uniprot:H3BPJ0;uniprot:H3BV99;uniprot:H3BQY9;uniprot:H3BU94;uniprot:H3BM38;uniprot:H3BR99;uniprot:H3BNG6;uniprot:H3BR18;uniprot:H3BNE1 +cyr61 GeneProduct ensembl:ENSG00000142871 "" ensembl:ENSG00000142871 ncbigene:3491 hgnc.symbol:CCN1 uniprot:A0A6Q8PGQ1;uniprot:O00622;uniprot:Q6FI18 +RHEB GeneProduct ensembl:ENSG00000106615 "" ensembl:ENSG00000106615 ncbigene:6009 hgnc.symbol:RHEB uniprot:F8WBL3;uniprot:Q15382;uniprot:A0A090N900;uniprot:C9J469;uniprot:C9J931 +SPTLC1 GeneProduct ensembl:ENSG00000090054 "" ensembl:ENSG00000090054 ncbigene:10558 hgnc.symbol:SPTLC1 uniprot:A0A2R8Y4S0;uniprot:A0A024R277;uniprot:A0A2R8Y6A2;uniprot:A0A2R8Y763;uniprot:O15269 +ADAR GeneProduct ensembl:ENSG00000160710 "" ensembl:ENSG00000160710 ncbigene:103 hgnc.symbol:ADAR uniprot:A0A3B3ISU1;uniprot:A0A7P0Z4F9;uniprot:A0A3B3ISX1;uniprot:A0A3B3IRQ9;uniprot:A0A7P0Z4K3;uniprot:A2IBT1;uniprot:A0A3B3ITG9;uniprot:A0A7P0TA14;uniprot:P55265 +FADS1 GeneProduct ensembl:ENSG00000149485 "" ensembl:ENSG00000149485 ncbigene:3992 hgnc.symbol:FADS1 uniprot:F5H2H3;uniprot:H0YB97;uniprot:F5H852;uniprot:F5H5X5;uniprot:C9JJB3;uniprot:F5H3U5;uniprot:F5H2R9;uniprot:F5H3P6;uniprot:C9J425;uniprot:F5H1Q7;uniprot:H7C2V0;uniprot:A0A0A0MR51;uniprot:F5H0Y2;uniprot:F5GWE3;uniprot:F5GYH4;uniprot:F5H8G5;uniprot:O60427 +CEP72 GeneProduct ensembl:ENSG00000112877 "" ensembl:ENSG00000112877 ncbigene:55722 hgnc.symbol:CEP72 uniprot:Q9P209 +MOV10 GeneProduct ensembl:ENSG00000155363 "" ensembl:ENSG00000155363 ncbigene:4343 hgnc.symbol:MOV10 uniprot:Q5JR04;uniprot:Q9HCE1 +LMNB2 GeneProduct ensembl:ENSG00000176619 "" ensembl:ENSG00000176619 ncbigene:84823 hgnc.symbol:LMNB2 uniprot:Q03252 +NEDD4 GeneProduct ensembl:ENSG00000069869 "" ensembl:ENSG00000069869 ncbigene:4734 hgnc.symbol:NEDD4 uniprot:H0Y9L1;uniprot:H0Y8X6;uniprot:P46934;uniprot:A0A3B3IUC1;uniprot:H0YA37;uniprot:H0Y8H4 +PWP1 GeneProduct ensembl:ENSG00000136045 "" ensembl:ENSG00000136045 ncbigene:11137 hgnc.symbol:PWP1 uniprot:A0A024RBH5;uniprot:F8VZ56;uniprot:Q13610;uniprot:B4DJV5 +TTC9C GeneProduct ensembl:ENSG00000162222 "" ensembl:ENSG00000162222 ncbigene:283237 hgnc.symbol:TTC9C uniprot:Q8N5M4;uniprot:E7EST3;uniprot:E9PKV8;uniprot:H0YDR3 +P4HA2 GeneProduct ensembl:ENSG00000072682 "" ensembl:ENSG00000072682 ncbigene:8974 hgnc.symbol:P4HA2 uniprot:C9JCP0;uniprot:E7EPI9;uniprot:C9JFJ1;uniprot:C9JN43;uniprot:O15460;uniprot:C9JX45;uniprot:E7ENX0;uniprot:A8MXE0;uniprot:C9JIG4;uniprot:E7ERI1 +ATP6V1F GeneProduct ensembl:ENSG00000128524 "" ensembl:ENSG00000128524 ncbigene:9296 hgnc.symbol:ATP6V1F uniprot:Q16864;uniprot:A4D1K0 +CARHSP1 GeneProduct ensembl:ENSG00000153048 "" ensembl:ENSG00000153048 ncbigene:23589 hgnc.symbol:CARHSP1 uniprot:H3BUY4;uniprot:H3BSW7;uniprot:I3L3X8;uniprot:H3BNU9;uniprot:H3BPY5;uniprot:H3BTK3;uniprot:Q9Y2V2;uniprot:H3BQY0 +ANAPC1 GeneProduct ensembl:ENSG00000153107 "" ensembl:ENSG00000153107 ncbigene:64682 hgnc.symbol:ANAPC1 uniprot:Q9H1A4;uniprot:A0A2R8YF63;uniprot:F8WAS1;uniprot:H0Y564 +NCL GeneProduct ensembl:ENSG00000115053 "" ensembl:ENSG00000115053 ncbigene:4691 hgnc.symbol:NCL uniprot:A0A7I2V2U7;uniprot:A0A7I2V699;uniprot:A0A7I2V349;uniprot:A0A7I2V2S8;uniprot:A0A7I2V428;uniprot:A0A7I2V506;uniprot:C9JLB1;uniprot:H7BY16;uniprot:P19338;uniprot:A0A7I2V5M5;uniprot:A0A7I2V3F3 +COMMD9 GeneProduct ensembl:ENSG00000110442 "" ensembl:ENSG00000110442 ncbigene:29099 hgnc.symbol:COMMD9 uniprot:E9PJ95;uniprot:Q53FR9;uniprot:Q9P000 +DHFR GeneProduct ensembl:ENSG00000188985 "" ensembl:ENSG00000188985 hgnc.symbol:DHFRP1 +DHX57 GeneProduct ensembl:ENSG00000163214 "" ensembl:ENSG00000163214 ncbigene:90957 hgnc.symbol:DHX57 uniprot:H7BZ23;uniprot:Q6P158;uniprot:H7C109;uniprot:A0A087WZ11;uniprot:A0A087WW12 +SEC23A GeneProduct ensembl:ENSG00000100934 "" ensembl:ENSG00000100934 ncbigene:10484 hgnc.symbol:SEC23A uniprot:G3V5K1;uniprot:G3V1W4;uniprot:G3V4V1;uniprot:G3V3G5;uniprot:Q15436;uniprot:F5H365;uniprot:G3V2R6;uniprot:G3V4Q2;uniprot:G3V5X8 +FAM96A GeneProduct ensembl:ENSG00000166797 "" ensembl:ENSG00000166797 ncbigene:84191 hgnc.symbol:CIAO2A uniprot:H0YLH6;uniprot:H0YKV4;uniprot:Q9H5X1 +PANX1 GeneProduct ensembl:ENSG00000110218 "" ensembl:ENSG00000110218 ncbigene:24145 hgnc.symbol:PANX1 uniprot:A0A024R397;uniprot:Q96RD7 +PGRMC1 GeneProduct ensembl:ENSG00000101856 "" ensembl:ENSG00000101856 ncbigene:10857 hgnc.symbol:PGRMC1 uniprot:Q6IB11;uniprot:O00264 +STX7 GeneProduct ensembl:ENSG00000079950 "" ensembl:ENSG00000079950 ncbigene:8417 hgnc.symbol:STX7 uniprot:O15400 +MYO1E GeneProduct ensembl:ENSG00000157483 "" ensembl:ENSG00000157483 ncbigene:4643 hgnc.symbol:MYO1E uniprot:Q12965;uniprot:H0YN00;uniprot:H0YLE5;uniprot:H0YNB0;uniprot:H0YLJ4;uniprot:H0YNQ8;uniprot:Q4KMR3 +TMED7 GeneProduct ensembl:ENSG00000134970 "" ensembl:ENSG00000134970 ncbigene:51014 hgnc.symbol:TMED7 uniprot:G3V2Y2;uniprot:Q9Y3B3 +SNX15 GeneProduct ensembl:ENSG00000110025 "" ensembl:ENSG00000110025 ncbigene:29907 hgnc.symbol:SNX15 uniprot:E9PR81;uniprot:E9PMW6;uniprot:E9PNI5;uniprot:E5KQS5;uniprot:E9PK26;uniprot:Q9NRS6 +NT5C3 GeneProduct ensembl:ENSG00000122643 "" ensembl:ENSG00000122643 ncbigene:51251 hgnc.symbol:NT5C3A uniprot:X6RM59;uniprot:B9A035;uniprot:A0A090N7U2;uniprot:C9K084;uniprot:A0A024RA81;uniprot:F8WDR0;uniprot:Q9H0P0 +CEBPB GeneProduct ensembl:ENSG00000172216 "" ensembl:ENSG00000172216 ncbigene:1051 hgnc.symbol:CEBPB uniprot:P17676 +ARF4 GeneProduct ensembl:ENSG00000168374 "" ensembl:ENSG00000168374 ncbigene:378 hgnc.symbol:ARF4 uniprot:P18085;uniprot:C9JAK5;uniprot:F8WDB3;uniprot:C9J6P1;uniprot:C9JPM4;uniprot:U3KQF2 +UTP15 GeneProduct ensembl:ENSG00000164338 "" ensembl:ENSG00000164338 ncbigene:84135 hgnc.symbol:UTP15 uniprot:Q8TED0;uniprot:H0Y8P4;uniprot:A0A1Y8EI88;uniprot:D6RF65 +METTL7A GeneProduct ensembl:ENSG00000185432 "" ensembl:ENSG00000185432 ncbigene:25840 hgnc.symbol:METTL7A uniprot:Q9H8H3;uniprot:F8VQX6;uniprot:A0A024R118;uniprot:H0YI09 +OPRS1 GeneProduct ensembl:ENSG00000147955 "" ensembl:ENSG00000147955 ncbigene:10280 hgnc.symbol:SIGMAR1 uniprot:B4DR71;uniprot:A0A7P0T9D5;uniprot:Q5T1J1;uniprot:Q99720;uniprot:A0A7P0TA12;uniprot:A0A7P0Z4C2;uniprot:A2A3U5 +ABCF2 GeneProduct ensembl:ENSG00000033050 "" ensembl:ENSG00000033050 ncbigene:10061 hgnc.symbol:ABCF2 uniprot:Q9UG63;uniprot:A0A090N7X1;uniprot:C9JHK9;uniprot:C9JZV3 +COIL GeneProduct ensembl:ENSG00000121058 "" ensembl:ENSG00000121058 ncbigene:8161 hgnc.symbol:COIL uniprot:P38432;uniprot:I3L369 +ARCN1 GeneProduct ensembl:ENSG00000095139 "" ensembl:ENSG00000095139 ncbigene:372 hgnc.symbol:ARCN1 uniprot:P48444;uniprot:E9PK34;uniprot:B0YIW5;uniprot:B0YIW6 +GTPBP3 GeneProduct ensembl:ENSG00000130299 "" ensembl:ENSG00000130299 ncbigene:84705 hgnc.symbol:GTPBP3 uniprot:M0R0S9;uniprot:M0QYW1;uniprot:M0QXA1;uniprot:M0R1X0;uniprot:Q969Y2;uniprot:M0R161 +SLC25A1 GeneProduct ensembl:ENSG00000100075 "" ensembl:ENSG00000100075 ncbigene:6576 hgnc.symbol:SLC25A1 uniprot:P53007;uniprot:B4DP62 +CSNK1D GeneProduct ensembl:ENSG00000141551 "" ensembl:ENSG00000141551 ncbigene:1453 hgnc.symbol:CSNK1D uniprot:J3KRM8;uniprot:P48730;uniprot:H7BYT1;uniprot:H0Y2N6;uniprot:J3QQU8;uniprot:J3QQI9;uniprot:J3KRS6;uniprot:B4DLF1;uniprot:J3QS70 +GSTM4 GeneProduct ensembl:ENSG00000168765 "" ensembl:ENSG00000168765 ncbigene:2948 hgnc.symbol:GSTM4 uniprot:Q03013;uniprot:A6NNT0;uniprot:A0A140VKE3 +IQGAP3 GeneProduct ensembl:ENSG00000183856 "" ensembl:ENSG00000183856 ncbigene:128239 hgnc.symbol:IQGAP3 uniprot:F2Z2E2;uniprot:Q86VI3 +TAF9B GeneProduct ensembl:ENSG00000187325 "" ensembl:ENSG00000187325 ncbigene:51616 hgnc.symbol:TAF9B uniprot:Q9HBM6 +CAP1 GeneProduct ensembl:ENSG00000131236 "" ensembl:ENSG00000131236 ncbigene:10487 hgnc.symbol:CAP1 uniprot:Q5T0R2;uniprot:Q5T0S3;uniprot:Q5T0R1;uniprot:Q5T0R8;uniprot:Q5T0R7;uniprot:Q5T0R9;uniprot:Q5T0R4;uniprot:Q5T0R3;uniprot:Q5T0R6;uniprot:Q01518;uniprot:Q5T0R5 +CPNE8 GeneProduct ensembl:ENSG00000139117 "" ensembl:ENSG00000139117 ncbigene:144402 hgnc.symbol:CPNE8 uniprot:E7ENV7;uniprot:Q86YQ8;uniprot:F8VZB5 +RAB30 GeneProduct ensembl:ENSG00000137502 "" ensembl:ENSG00000137502 ncbigene:27314 hgnc.symbol:RAB30 uniprot:E9PNB9;uniprot:E9PRX0;uniprot:A8K5R1;uniprot:E9PI18;uniprot:E9PJQ5;uniprot:E9PMJ1;uniprot:Q15771;uniprot:E9PLM3;uniprot:E9PPW9;uniprot:E9PQ07;uniprot:H0YDK7;uniprot:E9PS06;uniprot:E9PRF7 +SPRYD4 GeneProduct ensembl:ENSG00000176422 "" ensembl:ENSG00000176422 ncbigene:283377 hgnc.symbol:SPRYD4 uniprot:Q8WW59 +IDH1 GeneProduct ensembl:ENSG00000138413 "" ensembl:ENSG00000138413 ncbigene:3417 hgnc.symbol:IDH1 uniprot:A0A024R3Y6;uniprot:C9JLU6;uniprot:O75874;uniprot:C9JJE5;uniprot:C9J4N6 +DOCK7 GeneProduct ensembl:ENSG00000116641 "" ensembl:ENSG00000116641 ncbigene:85440 hgnc.symbol:DOCK7 uniprot:A0A0U1RQG7;uniprot:A0A1B0GUE9;uniprot:A0A0U1RQT6;uniprot:A0A1B0GWE0;uniprot:Q96N67;uniprot:A0A1B0GVW2;uniprot:A0A0C4DGY6;uniprot:A0A0U1RQJ5;uniprot:A0A0U1RR97;uniprot:A0A0U1RRC1 +RDH10 GeneProduct ensembl:ENSG00000121039 "" ensembl:ENSG00000121039 ncbigene:157506 hgnc.symbol:RDH10 uniprot:Q8IZV5;uniprot:E5RHJ9;uniprot:A0A024R7X6;uniprot:E5RK48 +SCAMP1 GeneProduct ensembl:ENSG00000085365 "" ensembl:ENSG00000085365 ncbigene:9522 hgnc.symbol:SCAMP1 uniprot:A0A087WZA6;uniprot:A0A087WXB0;uniprot:A0A087WTX8;uniprot:O15126;uniprot:A0A087WU14 +CTNNB1 GeneProduct ensembl:ENSG00000168036 "" ensembl:ENSG00000168036 ncbigene:1499 hgnc.symbol:CTNNB1 uniprot:A0A2R8Y6G0;uniprot:A0A2R8Y804;uniprot:A0A2R8Y815;uniprot:A0A2R8Y5A3;uniprot:C9IZ65;uniprot:A0A2R8Y5C3;uniprot:P35222;uniprot:A0A2R8Y7Z0;uniprot:A0A2R8YG06;uniprot:A0A2R8Y5Z1;uniprot:A0A2R8Y750;uniprot:A0A2R8YCH5;uniprot:A0A024R2Q3;uniprot:A0A2R8Y543;uniprot:B4DGU4 +MAPK12 / ERK5 GeneProduct ensembl:ENSG00000188130 "" ensembl:ENSG00000188130 ncbigene:6300 hgnc.symbol:MAPK12 uniprot:P53778;uniprot:A8MY48;uniprot:B5MDL5 +MAT2A GeneProduct ensembl:ENSG00000168906 "" ensembl:ENSG00000168906 ncbigene:4144 hgnc.symbol:MAT2A uniprot:A0A140VJP5;uniprot:P31153 +VEZT / vezatin GeneProduct ensembl:ENSG00000028203 "" ensembl:ENSG00000028203 ncbigene:55591 hgnc.symbol:VEZT uniprot:F8VXA0;uniprot:F8VVS3;uniprot:F8W8C2;uniprot:F8VRY3;uniprot:F8W0S0;uniprot:Q9HBM0;uniprot:F8VPN9;uniprot:F8VUB7;uniprot:F8W088;uniprot:F8VUG0;uniprot:F8W048;uniprot:F8VS43 +SNX6 GeneProduct ensembl:ENSG00000129515 "" ensembl:ENSG00000129515 ncbigene:58533 hgnc.symbol:SNX6 uniprot:G3V2U1;uniprot:G3V4Z5;uniprot:G3V5U2;uniprot:H0YJF8;uniprot:Q9UNH7;uniprot:G3V589;uniprot:G3V5X9;uniprot:A0A0A0MRI2 +PTBP2 GeneProduct ensembl:ENSG00000117569 "" ensembl:ENSG00000117569 ncbigene:58155 hgnc.symbol:PTBP2 uniprot:A0A6Q8PEZ3;uniprot:B4DI28;uniprot:Q9UKA9;uniprot:A0A6Q8PFC0;uniprot:A0A6Q8PH82;uniprot:A0A6Q8PFE6;uniprot:A0A6Q8PH43;uniprot:A0A7I2RVZ4;uniprot:A0A6Q8PFT8 +YIF1B GeneProduct ensembl:ENSG00000167645 "" ensembl:ENSG00000167645 ncbigene:90522 hgnc.symbol:YIF1B uniprot:K7EJQ6;uniprot:K7ERQ0;uniprot:K7ERY2;uniprot:K7EPQ7;uniprot:Q5BJH7 +BDNF GeneProduct ensembl:ENSG00000176697 "" ensembl:ENSG00000176697 ncbigene:627 hgnc.symbol:BDNF uniprot:P23560;uniprot:A0A0E3SU01;uniprot:E9PMP3 +COL4A2 GeneProduct ensembl:ENSG00000134871 "" ensembl:ENSG00000134871 ncbigene:1284 hgnc.symbol:COL4A2 uniprot:A0A3B3IRV2;uniprot:A0A3B3IT80;uniprot:P08572;uniprot:A0A3B3ITN7;uniprot:A2A352;uniprot:A0A3B3ITQ8;uniprot:A0A087WY39;uniprot:A0A3B3IS47;uniprot:A0A3B3IS04;uniprot:A0A024RDW8 +SLC4A10 GeneProduct ensembl:ENSG00000144290 "" ensembl:ENSG00000144290 ncbigene:57282 hgnc.symbol:SLC4A10 uniprot:E7EW28;uniprot:C9J240;uniprot:F8WDX9;uniprot:Q6U841 +SPCS3 GeneProduct ensembl:ENSG00000129128 "" ensembl:ENSG00000129128 ncbigene:60559 hgnc.symbol:SPCS3 uniprot:P61009 +RAB23 GeneProduct ensembl:ENSG00000112210 "" ensembl:ENSG00000112210 ncbigene:51715 hgnc.symbol:RAB23 uniprot:A0A024RD41;uniprot:Q9ULC3 +MYB GeneProduct ensembl:ENSG00000118513 "" ensembl:ENSG00000118513 ncbigene:4602 hgnc.symbol:MYB uniprot:E9PJ96;uniprot:E9PN92;uniprot:E9PJT2;uniprot:E9PLN0;uniprot:E9PPR4;uniprot:F8W8G5;uniprot:E9PMZ0;uniprot:E9PKZ3;uniprot:P10242;uniprot:Q708E3;uniprot:E9PIW4;uniprot:Q708E5;uniprot:E9PMQ0;uniprot:Q708E6;uniprot:E9PP87;uniprot:Q708E9;uniprot:Q708E8;uniprot:E9PN43;uniprot:A0A0C4DG19;uniprot:E9PQQ2;uniprot:E9PJF1;uniprot:A0A087WTI6;uniprot:H0YCN6;uniprot:E9PNH6;uniprot:E9PPL8 +BRI3BP GeneProduct ensembl:ENSG00000184992 "" ensembl:ENSG00000184992 ncbigene:140707 hgnc.symbol:BRI3BP uniprot:Q8WY22;uniprot:A0A5F9ZHY7 +ANKFY1 GeneProduct ensembl:ENSG00000185722 "" ensembl:ENSG00000185722 ncbigene:51479 hgnc.symbol:ANKFY1 uniprot:K7EPT2;uniprot:Q9P2R3;uniprot:I3L1Z9;uniprot:I3L3P8 +MRPS24 GeneProduct ensembl:ENSG00000062582 "" ensembl:ENSG00000062582 ncbigene:64951 hgnc.symbol:MRPS24 uniprot:F8VYR5;uniprot:Q96EL2 +SYNE2 GeneProduct ensembl:ENSG00000054654 "" ensembl:ENSG00000054654 ncbigene:23224 hgnc.symbol:SYNE2 uniprot:A0A669KBH2;uniprot:G3V2Q0;uniprot:G3V5X4;uniprot:A0A669KB22;uniprot:G3V3D4;uniprot:A0A669KB61;uniprot:A0A0C4DGK3;uniprot:A0A1W2PRN9;uniprot:A0A1W2PS37;uniprot:Q8WXH0;uniprot:G3V4T3;uniprot:A0A669KBG2;uniprot:G3V5N1 +HSD17B12 GeneProduct ensembl:ENSG00000149084 "" ensembl:ENSG00000149084 ncbigene:51144 hgnc.symbol:HSD17B12 uniprot:E9PI21;uniprot:A0A1B0GW85;uniprot:A0A1B0GVY6;uniprot:Q53GQ0;uniprot:A0A1B0GU83;uniprot:A0A1B0GV93;uniprot:A0A1B0GW27 +GALNT1 GeneProduct ensembl:ENSG00000141429 "" ensembl:ENSG00000141429 ncbigene:2589 hgnc.symbol:GALNT1 uniprot:K7EK46;uniprot:K7EJV8;uniprot:Q10472;uniprot:A0A024RC48 +TCL1A GeneProduct ensembl:ENSG00000100721 "" ensembl:ENSG00000100721 ncbigene:8115 hgnc.symbol:TCL1A uniprot:H0YJR9;uniprot:G3V4T4;uniprot:P56279;uniprot:A0A024R6G5 +NUFIP2 GeneProduct ensembl:ENSG00000108256 "" ensembl:ENSG00000108256 ncbigene:57532 hgnc.symbol:NUFIP2 uniprot:Q7Z417 +NM_014445 GeneProduct ensembl:ENSG00000120742 "" ensembl:ENSG00000120742 ncbigene:27230 hgnc.symbol:SERP1 uniprot:C9JUH5;uniprot:C9JSB0;uniprot:Q9Y6X1 +LYCAT GeneProduct ensembl:ENSG00000172954 "" ensembl:ENSG00000172954 ncbigene:253558 hgnc.symbol:LCLAT1 uniprot:Q6UWP7;uniprot:C9J6F4;uniprot:C9JA02;uniprot:C9K0C3;uniprot:F8WEY2;uniprot:C9JMW2;uniprot:C9JUV9;uniprot:C9J5S5;uniprot:C9JXY8 +PRPF40A GeneProduct ensembl:ENSG00000196504 "" ensembl:ENSG00000196504 ncbigene:55660 hgnc.symbol:PRPF40A uniprot:H7C2N3;uniprot:H0YG38;uniprot:H7BXZ7;uniprot:O75400;uniprot:A0A7N4I394;uniprot:F5H578 +CHAF1A GeneProduct ensembl:ENSG00000167670 "" ensembl:ENSG00000167670 ncbigene:10036 hgnc.symbol:CHAF1A uniprot:K7EPA1;uniprot:K7EME9;uniprot:Q13111;uniprot:K7EJF1;uniprot:K7ENC7 +TNFAIP2 GeneProduct ensembl:ENSG00000185215 "" ensembl:ENSG00000185215 ncbigene:7127 hgnc.symbol:TNFAIP2 uniprot:H0YM45;uniprot:H0YKR7;uniprot:H0YKY9;uniprot:H0YKI8;uniprot:H0YL88;uniprot:Q03169;uniprot:H0YLC0 +FUSIP1 GeneProduct ensembl:ENSG00000188529 "" ensembl:ENSG00000188529 ncbigene:10772 hgnc.symbol:SRSF10 uniprot:O75494;uniprot:R4GMP8;uniprot:A0A0S2Z504;uniprot:Q5JRI1;uniprot:Q6IQ42 +CLDN1 GeneProduct ensembl:ENSG00000163347 "" ensembl:ENSG00000163347 ncbigene:9076 hgnc.symbol:CLDN1 uniprot:A5JSJ9;uniprot:O95832 +ARFIP2 GeneProduct ensembl:ENSG00000132254 "" ensembl:ENSG00000132254 ncbigene:23647 hgnc.symbol:ARFIP2 uniprot:A0A087X1E4;uniprot:P53365;uniprot:E9PPY7;uniprot:E9PRV8 +SFXN1 GeneProduct ensembl:ENSG00000164466 "" ensembl:ENSG00000164466 ncbigene:94081 hgnc.symbol:SFXN1 uniprot:S4R2X2;uniprot:D6RFI0;uniprot:D6RDG7;uniprot:Q9H9B4;uniprot:D6RAE9;uniprot:H0Y9J5 +MAPK7 GeneProduct ensembl:ENSG00000166484 "" ensembl:ENSG00000166484 ncbigene:5598 hgnc.symbol:MAPK7 uniprot:S4R3I1;uniprot:C9JUK9;uniprot:J3KT50;uniprot:J3KT61;uniprot:I3L0J8;uniprot:A0A024QZ20;uniprot:Q13164 +ADIPOR2 GeneProduct ensembl:ENSG00000006831 "" ensembl:ENSG00000006831 ncbigene:79602 hgnc.symbol:ADIPOR2 uniprot:Q86V24 +CAND1 GeneProduct ensembl:ENSG00000111530 "" ensembl:ENSG00000111530 ncbigene:55832 hgnc.symbol:CAND1 uniprot:H0YH27;uniprot:Q86VP6;uniprot:A0A0C4DGH5;uniprot:F5H6I6 +NF2 GeneProduct ensembl:ENSG00000186575 "" ensembl:ENSG00000186575 ncbigene:4771 hgnc.symbol:NF2 uniprot:A0A5F9ZHA0;uniprot:A0A5K1VW66;uniprot:A0A024R1J8;uniprot:A0A024R1J9;uniprot:A0A5F9ZHD8;uniprot:P35240;uniprot:A0A024R1F6;uniprot:A0A024R1D9;uniprot:A0A024R1I0 +ARID2 GeneProduct ensembl:ENSG00000189079 "" ensembl:ENSG00000189079 ncbigene:196528 hgnc.symbol:ARID2 uniprot:A0A087WY37;uniprot:F8W108;uniprot:F8WCU9;uniprot:F8VWP4;uniprot:Q68CP9 +LRRC8A GeneProduct ensembl:ENSG00000136802 "" ensembl:ENSG00000136802 ncbigene:56262 hgnc.symbol:LRRC8A uniprot:Q8IWT6;uniprot:A0A024R892 +TMEM109 GeneProduct ensembl:ENSG00000110108 "" ensembl:ENSG00000110108 ncbigene:79073 hgnc.symbol:TMEM109 uniprot:Q9BVC6 +UNC93B1 GeneProduct ensembl:ENSG00000110057 "" ensembl:ENSG00000110057 ncbigene:81622 hgnc.symbol:UNC93B1 uniprot:Q9H1C4;uniprot:E9PR93;uniprot:E9PNE5 +PTBP1 GeneProduct ensembl:ENSG00000011304 "" ensembl:ENSG00000011304 ncbigene:5725 hgnc.symbol:PTBP1 uniprot:A0A7I2V4H6;uniprot:P26599;uniprot:A0A0D9SF20;uniprot:A0A0U1RRM4;uniprot:K7EKJ7;uniprot:K7ES59;uniprot:A6NLN1;uniprot:A0A6Q8PEX4;uniprot:A0A7I2V621;uniprot:K7ELW5;uniprot:K7EK45;uniprot:A0A087WUW5;uniprot:A0A087WTS6;uniprot:A0A087WU68 +USP1 GeneProduct ensembl:ENSG00000162607 "" ensembl:ENSG00000162607 ncbigene:7398 hgnc.symbol:USP1 uniprot:C9JC88;uniprot:C9JWX4;uniprot:O94782 +HBXIP GeneProduct ensembl:ENSG00000134248 "" ensembl:ENSG00000134248 ncbigene:10542 hgnc.symbol:LAMTOR5 uniprot:E9PLX3;uniprot:R4GMU8;uniprot:A0A0C4DGV4;uniprot:O43504 +CDCP1 GeneProduct ensembl:ENSG00000163814 "" ensembl:ENSG00000163814 ncbigene:64866 hgnc.symbol:CDCP1 uniprot:Q9H5V8 +AP3B1 GeneProduct ensembl:ENSG00000132842 "" ensembl:ENSG00000132842 ncbigene:8546 hgnc.symbol:AP3B1 uniprot:H0YBD0;uniprot:O00203;uniprot:A0A0S2Z5J4;uniprot:A0A0S2Z4Z4 +YWHAQ GeneProduct ensembl:ENSG00000134308 "" ensembl:ENSG00000134308 ncbigene:10971 hgnc.symbol:YWHAQ uniprot:P27348;uniprot:E9PG15 +MYLIP GeneProduct ensembl:ENSG00000007944 "" ensembl:ENSG00000007944 ncbigene:29116 hgnc.symbol:MYLIP uniprot:Q5TIA5;uniprot:Q8WY64 +TP53INP1 GeneProduct ensembl:ENSG00000164938 "" ensembl:ENSG00000164938 ncbigene:94241 hgnc.symbol:TP53INP1 uniprot:A0A024R9C8;uniprot:Q96A56 +MATR3 GeneProduct ensembl:ENSG00000015479 "" ensembl:ENSG00000015479 ncbigene:9782 hgnc.symbol:MATR3 uniprot:D6RBK5;uniprot:D6RBI2;uniprot:B3KM87;uniprot:D6REK4;uniprot:D6REM6;uniprot:P43243;uniprot:D6R991;uniprot:A0A1B0GX04;uniprot:D6RAY2;uniprot:D6RIA2;uniprot:D6RBS2;uniprot:H0Y8T4;uniprot:D6RE02;uniprot:D6R9F3 +PPP1R7 GeneProduct ensembl:ENSG00000115685 "" ensembl:ENSG00000115685 ncbigene:5510 hgnc.symbol:PPP1R7 uniprot:C9J177;uniprot:C9JRC4;uniprot:B5MBZ8;uniprot:H7C3Q5;uniprot:H7C118;uniprot:C9JD73;uniprot:Q15435;uniprot:A0A140VK83;uniprot:H7C003 +CDKAL1 GeneProduct ensembl:ENSG00000145996 "" ensembl:ENSG00000145996 ncbigene:54901 hgnc.symbol:CDKAL1 uniprot:Q5VV42 +TNFRSF10B GeneProduct ensembl:ENSG00000120889 "" ensembl:ENSG00000120889 ncbigene:8795 hgnc.symbol:TNFRSF10B uniprot:E9PBT3;uniprot:O14763 +PRKCI GeneProduct ensembl:ENSG00000163558 "" ensembl:ENSG00000163558 ncbigene:5584 hgnc.symbol:PRKCI uniprot:P41743 +PTPLAD1 GeneProduct ensembl:ENSG00000074696 "" ensembl:ENSG00000074696 ncbigene:51495 hgnc.symbol:HACD3 uniprot:H3BMZ1;uniprot:H3BPZ1;uniprot:Q9P035;uniprot:H3BRL8;uniprot:H3BS72 +PPIB GeneProduct ensembl:ENSG00000166794 "" ensembl:ENSG00000166794 ncbigene:5479 hgnc.symbol:PPIB uniprot:P23284;uniprot:A0A7P0T7U3;uniprot:A0A7P0Z497;uniprot:A0A7P0TB45 +VTI1B GeneProduct ensembl:ENSG00000100568 "" ensembl:ENSG00000100568 ncbigene:10490 hgnc.symbol:VTI1B uniprot:G3V5I2;uniprot:Q9UEU0;uniprot:H0YJL5;uniprot:H0YJJ5;uniprot:J3KMW2 +BCL6 GeneProduct ensembl:ENSG00000113916 "" ensembl:ENSG00000113916 ncbigene:604 hgnc.symbol:BCL6 uniprot:C9JL16;uniprot:A0A0C4DH53;uniprot:P41182;uniprot:C9JCS5 +GAK GeneProduct ensembl:ENSG00000178950 "" ensembl:ENSG00000178950 ncbigene:2580 hgnc.symbol:GAK uniprot:D6RF16;uniprot:H0Y9M4;uniprot:D6RAW3;uniprot:H0YA39;uniprot:O14976;uniprot:D6RAQ7;uniprot:D6RE78;uniprot:H0Y8H5;uniprot:D6RC24 +LAMC2 GeneProduct ensembl:ENSG00000058085 "" ensembl:ENSG00000058085 ncbigene:3918 hgnc.symbol:LAMC2 uniprot:Q13753 +ATP6V0E GeneProduct ensembl:ENSG00000113732 "" ensembl:ENSG00000113732 ncbigene:8992 hgnc.symbol:ATP6V0E1 uniprot:O15342;uniprot:J3KN48;uniprot:E5RHL5 +RBMS1 GeneProduct ensembl:ENSG00000153250 "" ensembl:ENSG00000153250 ncbigene:5937 hgnc.symbol:RBMS1 uniprot:E7EPF2;uniprot:P29558;uniprot:E7ETU5 +CDKN1C / p57 GeneProduct ensembl:ENSG00000129757 "" ensembl:ENSG00000129757 ncbigene:1028 hgnc.symbol:CDKN1C uniprot:A0A2R8YFP9;uniprot:P49918;uniprot:A6NK88 +DOCK5 GeneProduct ensembl:ENSG00000147459 "" ensembl:ENSG00000147459 ncbigene:80005 hgnc.symbol:DOCK5 uniprot:Q9H7D0;uniprot:H0Y7N4;uniprot:B9A015;uniprot:H0YB14 +NFIA GeneProduct ensembl:ENSG00000162599 "" ensembl:ENSG00000162599 ncbigene:4774 hgnc.symbol:NFIA uniprot:S4R308;uniprot:A0A590UJA3;uniprot:Q12857;uniprot:S4R3K4;uniprot:S4R3K5;uniprot:A0A590UK09;uniprot:B1AKN6;uniprot:S4R3W2;uniprot:B1AKN7;uniprot:A0A590UK38;uniprot:B1AKN8;uniprot:S4R3W6;uniprot:A0A590UJU2;uniprot:A0A590UK73;uniprot:A0A590UJ82;uniprot:B1AKN5;uniprot:A0A590UJ67 +PLEKHC1 GeneProduct ensembl:ENSG00000073712 "" ensembl:ENSG00000073712 ncbigene:10979 hgnc.symbol:FERMT2 uniprot:G3V281;uniprot:H0YJB6;uniprot:H0YJ34;uniprot:Q96AC1;uniprot:A0A024R687;uniprot:G3V379;uniprot:G3V5R2;uniprot:A0A0U1RRM8;uniprot:G3V3J0 +IGF2R GeneProduct ensembl:ENSG00000197081 "" ensembl:ENSG00000197081 ncbigene:3482 hgnc.symbol:IGF2R uniprot:A0A7I2YQS7;uniprot:A0A7I2V657;uniprot:A0A7I2V381;uniprot:P11717;uniprot:S4R328 +TRAM1 GeneProduct ensembl:ENSG00000067167 "" ensembl:ENSG00000067167 ncbigene:23471 hgnc.symbol:TRAM1 uniprot:Q15629;uniprot:G3XAN4;uniprot:Q6FHL3;uniprot:E5RFP8 +FAM105A GeneProduct ensembl:ENSG00000145569 "" ensembl:ENSG00000145569 ncbigene:54491 hgnc.symbol:OTULINL uniprot:Q9NUU6 +GEMIN7 GeneProduct ensembl:ENSG00000142252 "" ensembl:ENSG00000142252 ncbigene:79760 hgnc.symbol:GEMIN7 uniprot:Q9H840 +FNDC3A GeneProduct ensembl:ENSG00000102531 "" ensembl:ENSG00000102531 ncbigene:22862 hgnc.symbol:FNDC3A uniprot:H7C507;uniprot:A0A024RDV5;uniprot:Q9Y2H6;uniprot:G5E9X3;uniprot:A0A087X1M6;uniprot:A0A024RDT9 +RBM19 GeneProduct ensembl:ENSG00000122965 "" ensembl:ENSG00000122965 ncbigene:9904 hgnc.symbol:RBM19 uniprot:H0YIL2;uniprot:Q9Y4C8 +SERPINE2 GeneProduct ensembl:ENSG00000135919 "" ensembl:ENSG00000135919 ncbigene:5270 hgnc.symbol:SERPINE2 uniprot:A0A024R451;uniprot:C9JN98;uniprot:C9K031;uniprot:P07093;uniprot:A0A024R498;uniprot:C9JRK5 +FLJ13158 GeneProduct ensembl:ENSG00000137343 "" ensembl:ENSG00000137343 ncbigene:79969 hgnc.symbol:ATAT1 uniprot:Q5SQI0;uniprot:A0A1U9X797 +Ezh2 GeneProduct ensembl:ENSG00000106462 "" ensembl:ENSG00000106462 ncbigene:2146 hgnc.symbol:EZH2 uniprot:A0A090N8E9;uniprot:Q15910;uniprot:A0A804HJH1;uniprot:G3XAL2;uniprot:E9PDH6;uniprot:S4S3R8;uniprot:A0A804HLB8 +UBE2J1 GeneProduct ensembl:ENSG00000198833 "" ensembl:ENSG00000198833 ncbigene:51465 hgnc.symbol:UBE2J1 uniprot:Q9Y385 +MIRLET7B GeneProduct ensembl:ENSG00000284520 "" ensembl:ENSG00000284520 ncbigene:406884 hgnc.symbol:MIRLET7B +MIR155 GeneProduct ensembl:ENSG00000283904 "" ensembl:ENSG00000283904 ncbigene:406947 hgnc.symbol:MIR155 +MIR143 GeneProduct ensembl:ENSG00000284182 "" ensembl:ENSG00000284182 ncbigene:406935 hgnc.symbol:MIR143 +MIR133A1 GeneProduct ensembl:ENSG00000283927 "" ensembl:ENSG00000283927 ncbigene:406922 hgnc.symbol:MIR133A1 +MIR133A2 GeneProduct ensembl:ENSG00000284508 "" ensembl:ENSG00000284508 ncbigene:406923 hgnc.symbol:MIR133A2 +MIR17 GeneProduct ensembl:ENSG00000284536 "" ensembl:ENSG00000284536 ncbigene:406952 hgnc.symbol:MIR17 +MIR29B1 GeneProduct ensembl:ENSG00000283797 "" ensembl:ENSG00000283797 ncbigene:407024 hgnc.symbol:MIR29B1 +MIR29C GeneProduct ensembl:ENSG00000284214 "" ensembl:ENSG00000284214 ncbigene:407026 hgnc.symbol:MIR29C +MIR29B2 GeneProduct ensembl:ENSG00000284203 "" ensembl:ENSG00000284203 ncbigene:407025 hgnc.symbol:MIR29B2 +MIR20A GeneProduct ensembl:ENSG00000283762 "" ensembl:ENSG00000283762 ncbigene:406982 hgnc.symbol:MIR20A +MIR20B GeneProduct ensembl:ENSG00000284043 "" ensembl:ENSG00000284043 ncbigene:574032 hgnc.symbol:MIR20B +MIR34A GeneProduct ensembl:ENSG00000284357 "" ensembl:ENSG00000284357 ncbigene:407040 hgnc.symbol:MIR34A +MIR223 GeneProduct ensembl:ENSG00000284567 "" ensembl:ENSG00000284567 ncbigene:407008 hgnc.symbol:MIR223 +MIR92A2 GeneProduct ensembl:ENSG00000284538 "" ensembl:ENSG00000284538 ncbigene:407049 hgnc.symbol:MIR92A2 diff --git a/pathways/WP2004/WP2004.gpml b/pathways/WP2004/WP2004.gpml new file mode 100644 index 000000000..b3d873999 --- /dev/null +++ b/pathways/WP2004/WP2004.gpml @@ -0,0 +1,3005 @@ + + + This cataloge pathway was created using the database from "http://diana.cslab.ece.ntua.gr/tarbase/" with exclusions based on evidance type. This pathway only incldes miR targeted genes expressed in Lymphocyte cells. This pathway is meant for data mapping. + c81 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + 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+ MIR24-2 + + + + + + + MIR34A + + + + + + MIR370 + + + + + + MIR372 + + + + + + MIR378A + + + + + + MIR520H + + + + + + MIR222 + + + + + + MIR223 + + + + + + MIR92A2 + + + + + + MIR20A + + + + Name: miR-targeted genes in lymphocytes + Last Modified: 20241027161505 + Organism: Homo sapiens + + + diff --git a/pathways/WP2005/WP2005-bibliography.tsv b/pathways/WP2005/WP2005-bibliography.tsv new file mode 100644 index 000000000..6daf66eb3 --- /dev/null +++ b/pathways/WP2005/WP2005-bibliography.tsv @@ -0,0 +1,2 @@ +ID Database Citation +37986224 Pubmed "TarBase-v9.0 extends experimentally supported miRNA-gene interactions to cell-types and virally encoded miRNAs. Skoufos G, Kakoulidis P, Tastsoglou S, Zacharopoulou E, Kotsira V, Miliotis M, et al. Nucleic Acids Res. 2024 Jan 5;52(D1):D304–10. PubMed Europe PMC Scholia" diff --git a/pathways/WP2005/WP2005-datanodes.tsv b/pathways/WP2005/WP2005-datanodes.tsv new file mode 100644 index 000000000..e1edd1a1a --- /dev/null +++ b/pathways/WP2005/WP2005-datanodes.tsv @@ -0,0 +1,366 @@ +Label Type Identifier Comment Ensembl NCBI gene HGNC UniProt Wikidata ChEBI InChI PubChem ChemSpider HMDB KEGG LipidMaps +GNA13 GeneProduct ensembl:ENSG00000120063 "" ensembl:ENSG00000120063 ncbigene:10672 hgnc.symbol:GNA13 uniprot:A0A024R8M0;uniprot:Q14344 +TMED10 GeneProduct ensembl:ENSG00000170348 "" ensembl:ENSG00000170348 ncbigene:10972 hgnc.symbol:TMED10 uniprot:G3V2K7;uniprot:A0A024R6I3;uniprot:P49755 +CAPG GeneProduct ensembl:ENSG00000042493 "" ensembl:ENSG00000042493 ncbigene:822 hgnc.symbol:CAPG uniprot:E7ENU9;uniprot:P40121;uniprot:B8ZZL6;uniprot:H7C0X8;uniprot:V9HW69 +CPNE8 GeneProduct ensembl:ENSG00000139117 "" ensembl:ENSG00000139117 ncbigene:144402 hgnc.symbol:CPNE8 uniprot:E7ENV7;uniprot:Q86YQ8;uniprot:F8VZB5 +SLC4A7 GeneProduct ensembl:ENSG00000033867 "" ensembl:ENSG00000033867 ncbigene:9497 hgnc.symbol:SLC4A7 uniprot:A0A0A0MST8;uniprot:C9JRP1;uniprot:E9PFN4;uniprot:Q9Y6M7;uniprot:H7C3C4 +PICALM GeneProduct ensembl:ENSG00000073921 "" ensembl:ENSG00000073921 ncbigene:8301 hgnc.symbol:PICALM uniprot:E9PJT1;uniprot:H0YCY1;uniprot:A0A024R5L7;uniprot:E9PI56;uniprot:E9PK13;uniprot:H0YD48;uniprot:H0YE97;uniprot:Q13492;uniprot:E9PKP6;uniprot:H0YEY8;uniprot:H0YEH1;uniprot:E9PLJ8;uniprot:H0YEF7;uniprot:A0A024R5P1 +ANPEP GeneProduct ensembl:ENSG00000166825 "" ensembl:ENSG00000166825 ncbigene:290 hgnc.symbol:ANPEP uniprot:H0YM04;uniprot:A0A024RC61;uniprot:H0YMC1;uniprot:H0YLZ8;uniprot:H0YKT6;uniprot:P15144 +MAPK12 / ERK5 GeneProduct ensembl:ENSG00000188130 "" ensembl:ENSG00000188130 ncbigene:6300 hgnc.symbol:MAPK12 uniprot:P53778;uniprot:A8MY48;uniprot:B5MDL5 +TUSC2 / Fus1 , Fusion GeneProduct ensembl:ENSG00000114383 "" ensembl:ENSG00000114383 ncbigene:11334 hgnc.symbol:TUSC2 uniprot:O75896;uniprot:F2Z2A9;uniprot:G3V0I0 +ZNF622 GeneProduct ensembl:ENSG00000173545 "" ensembl:ENSG00000173545 ncbigene:90441 hgnc.symbol:ZNF622 uniprot:Q969S3 +ARHGDIA GeneProduct ensembl:ENSG00000141522 "" ensembl:ENSG00000141522 ncbigene:396 hgnc.symbol:ARHGDIA uniprot:J3KS60;uniprot:J3KRE2;uniprot:J3KTF8;uniprot:J3KRY1;uniprot:J3QQX2;uniprot:V9HWE8;uniprot:P52565 +SNAP23 GeneProduct ensembl:ENSG00000092531 "" ensembl:ENSG00000092531 ncbigene:8773 hgnc.symbol:SNAP23 uniprot:A0A024R9R8;uniprot:A8K287;uniprot:O00161;uniprot:H3BP15;uniprot:H3BPJ0;uniprot:H3BV99;uniprot:H3BQY9;uniprot:H3BU94;uniprot:H3BM38;uniprot:H3BR99;uniprot:H3BNG6;uniprot:H3BR18;uniprot:H3BNE1 +CACNA2D1 GeneProduct ensembl:ENSG00000153956 "" ensembl:ENSG00000153956 ncbigene:781 hgnc.symbol:CACNA2D1 uniprot:H0Y715;uniprot:P54289;uniprot:E7ERK3 +FMNL2 GeneProduct ensembl:ENSG00000157827 "" ensembl:ENSG00000157827 ncbigene:114793 hgnc.symbol:FMNL2 uniprot:Q96PY5;uniprot:C9IZY8 +SPRYD4 GeneProduct ensembl:ENSG00000176422 "" ensembl:ENSG00000176422 ncbigene:283377 hgnc.symbol:SPRYD4 uniprot:Q8WW59 +EGFR GeneProduct ensembl:ENSG00000146648 "" ensembl:ENSG00000146648 ncbigene:1956 hgnc.symbol:EGFR uniprot:P00533;uniprot:Q504U8;uniprot:C9JYS6 +STX7 GeneProduct ensembl:ENSG00000079950 "" ensembl:ENSG00000079950 ncbigene:8417 hgnc.symbol:STX7 uniprot:O15400 +DHX15 GeneProduct ensembl:ENSG00000109606 "" ensembl:ENSG00000109606 ncbigene:1665 hgnc.symbol:DHX15 uniprot:O43143 +PANX1 GeneProduct ensembl:ENSG00000110218 "" ensembl:ENSG00000110218 ncbigene:24145 hgnc.symbol:PANX1 uniprot:A0A024R397;uniprot:Q96RD7 +NAPG GeneProduct ensembl:ENSG00000134265 "" ensembl:ENSG00000134265 ncbigene:8774 hgnc.symbol:NAPG uniprot:J3QKW4;uniprot:Q99747;uniprot:Q6FHY4;uniprot:J3KTJ6;uniprot:J3QS28 +RDH10 GeneProduct ensembl:ENSG00000121039 "" ensembl:ENSG00000121039 ncbigene:157506 hgnc.symbol:RDH10 uniprot:Q8IZV5;uniprot:E5RHJ9;uniprot:A0A024R7X6;uniprot:E5RK48 +SYPL1 GeneProduct ensembl:ENSG00000008282 "" ensembl:ENSG00000008282 ncbigene:6856 hgnc.symbol:SYPL1 uniprot:A0A0U1RQT9;uniprot:A4D0R1;uniprot:C9JYN0;uniprot:H7C4J8;uniprot:Q16563 +WDFY1 GeneProduct ensembl:ENSG00000085449 "" ensembl:ENSG00000085449 ncbigene:57590 hgnc.symbol:WDFY1 uniprot:A0A024R488;uniprot:C9JJ54;uniprot:Q8IWB7 +TH1L GeneProduct ensembl:ENSG00000101158 "" ensembl:ENSG00000101158 ncbigene:51497 hgnc.symbol:NELFCD uniprot:Q8IXH7;uniprot:X6RLT1;uniprot:H0UI80 +CD164 GeneProduct ensembl:ENSG00000135535 "" ensembl:ENSG00000135535 ncbigene:8763 hgnc.symbol:CD164 uniprot:D6R9B4;uniprot:Q04900 +MET GeneProduct ensembl:ENSG00000105976 "" ensembl:ENSG00000105976 ncbigene:4233 hgnc.symbol:MET uniprot:A0A024R759;uniprot:P08581;uniprot:A0A024R728;uniprot:C9JKM5;uniprot:H7C130;uniprot:H7C174 +POLA2 GeneProduct ensembl:ENSG00000014138 "" ensembl:ENSG00000014138 ncbigene:23649 hgnc.symbol:POLA2 uniprot:Q14181;uniprot:H0YDR7;uniprot:E9PIQ6;uniprot:E9PQ99 +BACE1 / Beta-Secretase 1 GeneProduct ensembl:ENSG00000186318 "" ensembl:ENSG00000186318 ncbigene:23621 hgnc.symbol:BACE1 uniprot:U3KPS1;uniprot:B7Z3Z4;uniprot:A0A7P0T924;uniprot:P56817;uniprot:Q76KP0;uniprot:B7Z3K2;uniprot:E9PJG7;uniprot:A0A024R3D5;uniprot:A0A024R3D7;uniprot:A0A024R3E8;uniprot:A0A024R3F9;uniprot:A0A7P0TAB4 +FNDC3B GeneProduct ensembl:ENSG00000075420 "" ensembl:ENSG00000075420 ncbigene:64778 hgnc.symbol:FNDC3B uniprot:C9JKH7;uniprot:Q53EP0 +CBFB GeneProduct ensembl:ENSG00000067955 "" ensembl:ENSG00000067955 ncbigene:865 hgnc.symbol:CBFB uniprot:J3KRT0;uniprot:A0A024R6X2;uniprot:H3BSC0;uniprot:Q13951;uniprot:J3KS23;uniprot:A0A494C0A9;uniprot:J3KTD8 +RAB6A GeneProduct ensembl:ENSG00000175582 "" ensembl:ENSG00000175582 ncbigene:5870 hgnc.symbol:RAB6A uniprot:A0A024R5J5;uniprot:F5H3K7;uniprot:F5GX61;uniprot:A0A024R5H8;uniprot:P20340 +SCYL1 GeneProduct ensembl:ENSG00000142186 "" ensembl:ENSG00000142186 ncbigene:57410 hgnc.symbol:SCYL1 uniprot:E9PPN3;uniprot:H0YCI6;uniprot:E9PS17;uniprot:Q96KG9;uniprot:H0YDH0;uniprot:E9PK59 +KIT GeneProduct ensembl:ENSG00000157404 "" ensembl:ENSG00000157404 ncbigene:3815 hgnc.symbol:KIT uniprot:A0A0U2N547;uniprot:P10721 +PPIF GeneProduct ensembl:ENSG00000108179 "" ensembl:ENSG00000108179 ncbigene:10105 hgnc.symbol:PPIF uniprot:P30405;uniprot:A0A024QZS4;uniprot:R4GN99;uniprot:H0Y548 +SLC7A11 GeneProduct ensembl:ENSG00000151012 "" ensembl:ENSG00000151012 ncbigene:23657 hgnc.symbol:SLC7A11 uniprot:H0Y9F9;uniprot:Q9UPY5 +E2F3 GeneProduct ensembl:ENSG00000112242 "" ensembl:ENSG00000112242 ncbigene:1871 hgnc.symbol:E2F3 uniprot:O00716 +ATP6V1C1 GeneProduct ensembl:ENSG00000155097 "" ensembl:ENSG00000155097 ncbigene:528 hgnc.symbol:ATP6V1C1 uniprot:P21283;uniprot:A0A024R9I0;uniprot:E7EV59 +TMEM87A GeneProduct ensembl:ENSG00000103978 "" ensembl:ENSG00000103978 ncbigene:25963 hgnc.symbol:TMEM87A uniprot:H3BTS6;uniprot:H3BM87;uniprot:H3BUZ1;uniprot:Q8NBN3;uniprot:H3BSZ0;uniprot:H3BMU0;uniprot:H3BRG0;uniprot:H3BPJ4 +NCL GeneProduct ensembl:ENSG00000115053 "" ensembl:ENSG00000115053 ncbigene:4691 hgnc.symbol:NCL uniprot:A0A7I2V2U7;uniprot:A0A7I2V699;uniprot:A0A7I2V349;uniprot:A0A7I2V2S8;uniprot:A0A7I2V428;uniprot:A0A7I2V506;uniprot:C9JLB1;uniprot:H7BY16;uniprot:P19338;uniprot:A0A7I2V5M5;uniprot:A0A7I2V3F3 +HDAC4 GeneProduct ensembl:ENSG00000068024 "" ensembl:ENSG00000068024 ncbigene:9759 hgnc.symbol:HDAC4 uniprot:H7BZT3;uniprot:C9J481;uniprot:A0A7I2SVS4;uniprot:C9J0X4;uniprot:H7C397;uniprot:P56524 +RHOG GeneProduct ensembl:ENSG00000177105 "" ensembl:ENSG00000177105 ncbigene:391 hgnc.symbol:RHOG uniprot:Q6ICQ8;uniprot:P84095 +SPARC GeneProduct ensembl:ENSG00000113140 "" ensembl:ENSG00000113140 ncbigene:6678 hgnc.symbol:SPARC uniprot:F5GY03;uniprot:F5H4E2;uniprot:E5RK62;uniprot:E5RJA5;uniprot:P09486 +Mcl1 GeneProduct ensembl:ENSG00000143384 "" ensembl:ENSG00000143384 ncbigene:574406;ncbigene:4170 hgnc.symbol:MCL1 uniprot:Q07820;uniprot:A0A087WT64;uniprot:A0A7I2V2W2 +ARID4B / Rbp1-like GeneProduct ensembl:ENSG00000054267 "" ensembl:ENSG00000054267 ncbigene:51742 hgnc.symbol:ARID4B uniprot:H7C5R6;uniprot:X6RCR8;uniprot:H0Y7Y8;uniprot:Q4LE39 +IFRD1 GeneProduct ensembl:ENSG00000006652 "" ensembl:ENSG00000006652 ncbigene:3475 hgnc.symbol:IFRD1 uniprot:E9PMY4;uniprot:C9J311;uniprot:C9JLG5;uniprot:C9J7U6;uniprot:A0A6Q8PFA5;uniprot:C9JNM6;uniprot:A4D0U1;uniprot:C9JA65;uniprot:A0A6Q8PF03;uniprot:C9JK78;uniprot:A0A6Q8PH75;uniprot:O00458;uniprot:H0YEE3;uniprot:A0A6Q8PHN0 +EHMT1 GeneProduct ensembl:ENSG00000181090 "" ensembl:ENSG00000181090 ncbigene:79813 hgnc.symbol:EHMT1 uniprot:A0A0D9SEP2;uniprot:A0A0D9SFS4;uniprot:A0A1B0GU48;uniprot:A0A1B0GW79;uniprot:A0A0D9SEQ1;uniprot:A0A1B0GTP4;uniprot:A0A1B0GW12;uniprot:A0A0D9SER3;uniprot:A0A1B0GV89;uniprot:A0A1W2PPZ7;uniprot:A0A1B0GVZ8;uniprot:A0A0C4DGF8;uniprot:A0A0D9SFX4;uniprot:Q9H9B1;uniprot:A0A1B0GUD1;uniprot:A0A0D9SEY2;uniprot:A0A1B0GV09;uniprot:A0A0D9SFD7;uniprot:A0A0D9SFG7;uniprot:A0A1B0GWF6;uniprot:A0A0D9SFM6;uniprot:A0A0D9SF38;uniprot:A0A0D9SER9 +PDLIM5 GeneProduct ensembl:ENSG00000163110 "" ensembl:ENSG00000163110 ncbigene:10611 hgnc.symbol:PDLIM5 uniprot:A0A0D9SFR4;uniprot:Q96HC4;uniprot:A0A0A0MSP3;uniprot:H0Y929;uniprot:H0YBI4;uniprot:A0A0D9SFW3;uniprot:D6RAA1;uniprot:H0Y8Y3;uniprot:D6RGG6 +CTNNB1 GeneProduct ensembl:ENSG00000168036 "" ensembl:ENSG00000168036 ncbigene:1499 hgnc.symbol:CTNNB1 uniprot:A0A2R8Y6G0;uniprot:A0A2R8Y804;uniprot:A0A2R8Y815;uniprot:A0A2R8Y5A3;uniprot:C9IZ65;uniprot:A0A2R8Y5C3;uniprot:P35222;uniprot:A0A2R8Y7Z0;uniprot:A0A2R8YG06;uniprot:A0A2R8Y5Z1;uniprot:A0A2R8Y750;uniprot:A0A2R8YCH5;uniprot:A0A024R2Q3;uniprot:A0A2R8Y543;uniprot:B4DGU4 +FUSIP1 GeneProduct ensembl:ENSG00000188529 "" ensembl:ENSG00000188529 ncbigene:10772 hgnc.symbol:SRSF10 uniprot:O75494;uniprot:R4GMP8;uniprot:A0A0S2Z504;uniprot:Q5JRI1;uniprot:Q6IQ42 +SPCS3 GeneProduct ensembl:ENSG00000129128 "" ensembl:ENSG00000129128 ncbigene:60559 hgnc.symbol:SPCS3 uniprot:P61009 +IRS1 GeneProduct ensembl:ENSG00000169047 "" ensembl:ENSG00000169047 ncbigene:3667 hgnc.symbol:IRS1 uniprot:P35568 +MBNL1 GeneProduct ensembl:ENSG00000152601 "" ensembl:ENSG00000152601 ncbigene:4154 hgnc.symbol:MBNL1 uniprot:H7C4Y1;uniprot:C9J7P7;uniprot:Q86VM6;uniprot:A0A0A0MQX8;uniprot:C9JP00;uniprot:H7C4T5;uniprot:C9JCX1;uniprot:C9J4T8;uniprot:Q9NR56 +TICAM2 GeneProduct ensembl:ENSG00000134970 "" ensembl:ENSG00000134970 ncbigene:51014 hgnc.symbol:TMED7 uniprot:G3V2Y2;uniprot:Q9Y3B3 +MTHFD2 GeneProduct ensembl:ENSG00000065911 "" ensembl:ENSG00000065911 ncbigene:10797 hgnc.symbol:MTHFD2 uniprot:F8WF89;uniprot:A0A7I2V2U6;uniprot:P13995;uniprot:B9A062;uniprot:F8WF06;uniprot:B8ZZU9;uniprot:A0A7I2V482;uniprot:A0A7I2V2G4;uniprot:A0A7I2V3T1;uniprot:A0A7I2YQD4 +NT5E GeneProduct ensembl:ENSG00000135318 "" ensembl:ENSG00000135318 ncbigene:4907 hgnc.symbol:NT5E uniprot:H0Y3X5;uniprot:Q96B60;uniprot:H0Y7R7;uniprot:P21589 +SH3BGRL3 GeneProduct ensembl:ENSG00000142669 "" ensembl:ENSG00000142669 ncbigene:83442 hgnc.symbol:SH3BGRL3 uniprot:Q9H299;uniprot:Q5T123 +NAT6 GeneProduct ensembl:ENSG00000186792 "" ensembl:ENSG00000186792 ncbigene:8372 hgnc.symbol:HYAL3 uniprot:O43820;uniprot:C9JB51 +UAP1 GeneProduct ensembl:ENSG00000117143 "" ensembl:ENSG00000117143 ncbigene:6675 hgnc.symbol:UAP1 uniprot:Q16222;uniprot:A0A140VKC0 +TMED2 GeneProduct ensembl:ENSG00000086598 "" ensembl:ENSG00000086598 ncbigene:10959 hgnc.symbol:TMED2 uniprot:E7EQ72;uniprot:F5GX39;uniprot:Q15363;uniprot:Q6FHT8 +CARHSP1 GeneProduct ensembl:ENSG00000153048 "" ensembl:ENSG00000153048 ncbigene:23589 hgnc.symbol:CARHSP1 uniprot:H3BUY4;uniprot:H3BSW7;uniprot:I3L3X8;uniprot:H3BNU9;uniprot:H3BPY5;uniprot:H3BTK3;uniprot:Q9Y2V2;uniprot:H3BQY0 +CHORDC1 GeneProduct ensembl:ENSG00000110172 "" ensembl:ENSG00000110172 ncbigene:26973 hgnc.symbol:CHORDC1 uniprot:Q9UHD1;uniprot:E9PL00;uniprot:E9PIF7;uniprot:E9PHZ2;uniprot:E9PIZ4;uniprot:E9PPQ5;uniprot:E9PSD5 +NRP1 GeneProduct ensembl:ENSG00000099250 "" ensembl:ENSG00000099250 ncbigene:8829 hgnc.symbol:NRP1 uniprot:H0Y7Z2;uniprot:E9PEP6;uniprot:E7EX60;uniprot:H0Y4N6;uniprot:V9GYL7;uniprot:Q5JWQ2;uniprot:Q5JWQ4;uniprot:H0Y4A0;uniprot:Q5JWQ6;uniprot:Q5T7F0;uniprot:O14786 +ESR1 GeneProduct ensembl:ENSG00000091831 "" ensembl:ENSG00000091831 ncbigene:2099 hgnc.symbol:ESR1 uniprot:Q9H2M1;uniprot:Q9H2M2;uniprot:B0QYW7;uniprot:P03372;uniprot:Q5T5H8;uniprot:G4XH65;uniprot:H0Y4W6;uniprot:Q9UE35 +KCNQ1 GeneProduct ensembl:ENSG00000053918 "" ensembl:ENSG00000053918 ncbigene:3784 hgnc.symbol:KCNQ1 uniprot:A0A2R8YDV1;uniprot:P51787;uniprot:A0A2R8YEQ9;uniprot:E9PPZ0;uniprot:F8W824 +UBE2J1 GeneProduct ensembl:ENSG00000198833 "" ensembl:ENSG00000198833 ncbigene:51465 hgnc.symbol:UBE2J1 uniprot:Q9Y385 +IGF2BP1 GeneProduct ensembl:ENSG00000159217 "" ensembl:ENSG00000159217 ncbigene:10642 hgnc.symbol:IGF2BP1 uniprot:Q9NZI8 +TPM2 GeneProduct ensembl:ENSG00000198467 "" ensembl:ENSG00000198467 ncbigene:7169 hgnc.symbol:TPM2 uniprot:A7XZE4;uniprot:P07951;uniprot:U3KQK2;uniprot:Q5TCU3;uniprot:V9HW25;uniprot:A0A2R8Y6A3 +ADIPOR2 GeneProduct ensembl:ENSG00000006831 "" ensembl:ENSG00000006831 ncbigene:79602 hgnc.symbol:ADIPOR2 uniprot:Q86V24 +RAI14 GeneProduct ensembl:ENSG00000039560 "" ensembl:ENSG00000039560 ncbigene:26064 hgnc.symbol:RAI14 uniprot:Q9P0K7;uniprot:D6RE17;uniprot:D6REL2;uniprot:D6RDL2;uniprot:D6RBY4;uniprot:D6RF74;uniprot:D6RBW6;uniprot:D6R9G6;uniprot:D6RB27;uniprot:D6R9G4;uniprot:D6RB25 +TMEM109 GeneProduct ensembl:ENSG00000110108 "" ensembl:ENSG00000110108 ncbigene:79073 hgnc.symbol:TMEM109 uniprot:Q9BVC6 +cyr61 GeneProduct ensembl:ENSG00000142871 "" ensembl:ENSG00000142871 ncbigene:3491 hgnc.symbol:CCN1 uniprot:A0A6Q8PGQ1;uniprot:O00622;uniprot:Q6FI18 +ASH2L GeneProduct ensembl:ENSG00000129691 "" ensembl:ENSG00000129691 ncbigene:9070 hgnc.symbol:ASH2L uniprot:E5RFH5;uniprot:H0YAQ0;uniprot:E5RHM1;uniprot:F5H8F7;uniprot:H0YBF6;uniprot:Q9UBL3 +ATP2A2 GeneProduct ensembl:ENSG00000174437 "" ensembl:ENSG00000174437 ncbigene:488 hgnc.symbol:ATP2A2 uniprot:A0A0C4DH86;uniprot:A0A0S2Z3L2;uniprot:H7C5W9;uniprot:P16615;uniprot:J3QSY6;uniprot:F8W1Z7 +MAPK14 GeneProduct ensembl:ENSG00000112062 "" ensembl:ENSG00000112062 ncbigene:1432 hgnc.symbol:MAPK14 uniprot:L7RSM2;uniprot:B5TY33;uniprot:Q16539;uniprot:B4E0K5;uniprot:E7EX54;uniprot:H7C4E2;uniprot:A0A024RD15 +TLOC1 GeneProduct ensembl:ENSG00000008952 "" ensembl:ENSG00000008952 ncbigene:7095 hgnc.symbol:SEC62 uniprot:F8WF48;uniprot:F8WCJ7;uniprot:Q99442;uniprot:F8WDG8 +MYO10 GeneProduct ensembl:ENSG00000145555 "" ensembl:ENSG00000145555 ncbigene:4651 hgnc.symbol:MYO10 uniprot:E9PCN3;uniprot:Q9HD67;uniprot:D6RGD1;uniprot:E9PEW5;uniprot:A0A0A0MQX1 +COL1A2 GeneProduct ensembl:ENSG00000164692 "" ensembl:ENSG00000164692 ncbigene:1278 hgnc.symbol:COL1A2 uniprot:P08123;uniprot:A0A0S2Z3H5 +DOCK7 GeneProduct ensembl:ENSG00000116641 "" ensembl:ENSG00000116641 ncbigene:85440 hgnc.symbol:DOCK7 uniprot:A0A0U1RQG7;uniprot:A0A1B0GUE9;uniprot:A0A0U1RQT6;uniprot:A0A1B0GWE0;uniprot:Q96N67;uniprot:A0A1B0GVW2;uniprot:A0A0C4DGY6;uniprot:A0A0U1RQJ5;uniprot:A0A0U1RR97;uniprot:A0A0U1RRC1 +BCL2 GeneProduct ensembl:ENSG00000171791 "" ensembl:ENSG00000171791 ncbigene:596 hgnc.symbol:BCL2 uniprot:A0A7I2V3S7;uniprot:P10415;uniprot:A0A024R2B3;uniprot:A0A024R2C4;uniprot:A0A7I2V5Q7;uniprot:A0A7I2V4W1;uniprot:A0A7I2V5Q9 +SYNE1 GeneProduct ensembl:ENSG00000131018 "" ensembl:ENSG00000131018 ncbigene:23345 hgnc.symbol:SYNE1 uniprot:A0A5F9ZHB2;uniprot:Q8NF91;uniprot:A0A5F9ZHD7;uniprot:F5GXQ8;uniprot:F5GYQ7;uniprot:F5H422;uniprot:I6XKI8;uniprot:H0YFT4;uniprot:F5H4Q0;uniprot:F5GZ83;uniprot:F8WAI0;uniprot:A0A5F9ZI52;uniprot:A0A5F9ZHR3;uniprot:F5H6R8;uniprot:B7Z9Y6;uniprot:Q5JV20;uniprot:A0A5F9ZHE1;uniprot:A0A5F9ZHI3;uniprot:A0A5F9ZH87;uniprot:A0A5F9ZH00;uniprot:A0A0C4DH48;uniprot:A0A5F9ZH86;uniprot:H0Y326;uniprot:A0A0C4DG40;uniprot:H0Y325;uniprot:H0YGD3 +CDKN1B / KIP1, p2 GeneProduct ensembl:ENSG00000111276 "" ensembl:ENSG00000111276 ncbigene:1027 hgnc.symbol:CDKN1B uniprot:Q6I9V6;uniprot:E7ES52;uniprot:P46527;uniprot:H7C2T1 +NEDD4 GeneProduct ensembl:ENSG00000069869 "" ensembl:ENSG00000069869 ncbigene:4734 hgnc.symbol:NEDD4 uniprot:H0Y9L1;uniprot:H0Y8X6;uniprot:P46934;uniprot:A0A3B3IUC1;uniprot:H0YA37;uniprot:H0Y8H4 +SHOC2 GeneProduct ensembl:ENSG00000108061 "" ensembl:ENSG00000108061 ncbigene:8036 hgnc.symbol:SHOC2 uniprot:Q9UQ13;uniprot:X6RI37 +PTPRF GeneProduct ensembl:ENSG00000142949 "" ensembl:ENSG00000142949 ncbigene:5792 hgnc.symbol:PTPRF uniprot:H0Y380;uniprot:H0Y4H1;uniprot:H0Y7Z9;uniprot:A2A437;uniprot:H0Y6Z7;uniprot:P10586 +ATP6V0A1 GeneProduct ensembl:ENSG00000033627 "" ensembl:ENSG00000033627 ncbigene:535 hgnc.symbol:ATP6V0A1 uniprot:K7EN36;uniprot:K7ERA0;uniprot:K7ENA1;uniprot:K7EM24;uniprot:K7EQW2;uniprot:K7EPG4;uniprot:B7Z2A9;uniprot:K7ELZ6;uniprot:Q93050;uniprot:F5H1T6;uniprot:K7ERA6;uniprot:B7Z641 +GAK GeneProduct ensembl:ENSG00000178950 "" ensembl:ENSG00000178950 ncbigene:2580 hgnc.symbol:GAK uniprot:D6RF16;uniprot:H0Y9M4;uniprot:D6RAW3;uniprot:H0YA39;uniprot:O14976;uniprot:D6RAQ7;uniprot:D6RE78;uniprot:H0Y8H5;uniprot:D6RC24 +DNMT3A GeneProduct ensembl:ENSG00000119772 "" ensembl:ENSG00000119772 ncbigene:1788 hgnc.symbol:DNMT3A uniprot:Q9Y6K1;uniprot:F8WE91;uniprot:A0A0C4DG02 +HMGA1 GeneProduct ensembl:ENSG00000137309 "" ensembl:ENSG00000137309 ncbigene:3159 hgnc.symbol:HMGA1 uniprot:A0A669KAX1;uniprot:P17096;uniprot:Q5T6U8 +ERBB2 GeneProduct ensembl:ENSG00000141736 "" ensembl:ENSG00000141736 ncbigene:2064 hgnc.symbol:ERBB2 uniprot:J3QL83;uniprot:J3QLV2;uniprot:J3KRI9;uniprot:F5H1T4;uniprot:J3KTI5;uniprot:P04626;uniprot:X5DNK3;uniprot:J3QRJ7;uniprot:J3QLU9;uniprot:J3QRX1;uniprot:B4DTR1 +SDCBP GeneProduct ensembl:ENSG00000137575 "" ensembl:ENSG00000137575 ncbigene:6386 hgnc.symbol:SDCBP uniprot:B4DHN5;uniprot:O00560;uniprot:G5EA09;uniprot:A0A024R7Z5;uniprot:E9PBU7 +CLDN1 GeneProduct ensembl:ENSG00000163347 "" ensembl:ENSG00000163347 ncbigene:9076 hgnc.symbol:CLDN1 uniprot:A5JSJ9;uniprot:O95832 +LMNB2 GeneProduct ensembl:ENSG00000176619 "" ensembl:ENSG00000176619 ncbigene:84823 hgnc.symbol:LMNB2 uniprot:Q03252 +TTC9C GeneProduct ensembl:ENSG00000162222 "" ensembl:ENSG00000162222 ncbigene:283237 hgnc.symbol:TTC9C uniprot:Q8N5M4;uniprot:E7EST3;uniprot:E9PKV8;uniprot:H0YDR3 +PXDN GeneProduct ensembl:ENSG00000130508 "" ensembl:ENSG00000130508 ncbigene:7837 hgnc.symbol:PXDN uniprot:H7C1W1;uniprot:C9J4I9;uniprot:H7C300;uniprot:Q92626;uniprot:H7C3W2 +MTPN GeneProduct ensembl:ENSG00000105887 "" ensembl:ENSG00000105887 ncbigene:136319 hgnc.symbol:MTPN uniprot:Q69YG1;uniprot:P58546;uniprot:C9JL85 +TNFRSF10B GeneProduct ensembl:ENSG00000120889 "" ensembl:ENSG00000120889 ncbigene:8795 hgnc.symbol:TNFRSF10B uniprot:E9PBT3;uniprot:O14763 +TPM3 GeneProduct ensembl:ENSG00000143549 "" ensembl:ENSG00000143549 ncbigene:7170 hgnc.symbol:TPM3 uniprot:A0A494C0P6;uniprot:Q5VU61;uniprot:A0A494C034;uniprot:D6R904;uniprot:J3KN67;uniprot:D6RGJ6;uniprot:P06753;uniprot:A0A0S2Z4G4;uniprot:A0A2R2Y2Q3;uniprot:A0A087WWU8;uniprot:A0A0S2Z4I4;uniprot:A0A494C0G0 +RFT1 GeneProduct ensembl:ENSG00000163933 "" ensembl:ENSG00000163933 ncbigene:91869 hgnc.symbol:RFT1 uniprot:C9JP01;uniprot:B5MDE0;uniprot:Q96AA3 +MARS2 GeneProduct ensembl:ENSG00000152428 "" +ITGB4 GeneProduct ensembl:ENSG00000132470 "" ensembl:ENSG00000132470 ncbigene:3691 hgnc.symbol:ITGB4 uniprot:J3QQL2;uniprot:J3QRK0;uniprot:A0A024R8K7;uniprot:A0A024R8T0;uniprot:P16144;uniprot:J3KSH9 +FNDC3A GeneProduct ensembl:ENSG00000102531 "" ensembl:ENSG00000102531 ncbigene:22862 hgnc.symbol:FNDC3A uniprot:H7C507;uniprot:A0A024RDV5;uniprot:Q9Y2H6;uniprot:G5E9X3;uniprot:A0A087X1M6;uniprot:A0A024RDT9 +NOTCH2 GeneProduct ensembl:ENSG00000134250 "" ensembl:ENSG00000134250 ncbigene:4853 hgnc.symbol:NOTCH2 uniprot:A0A494C049;uniprot:A0A494C1U9;uniprot:A0A494C1H8;uniprot:Q04721;uniprot:A0A494C1F1;uniprot:A0A1W2PQQ5 +TPM4 GeneProduct ensembl:ENSG00000167460 "" ensembl:ENSG00000167460 ncbigene:7171 hgnc.symbol:TPM4 uniprot:A0A2R8YH90;uniprot:K7ERG3;uniprot:A0A2R8YGX3;uniprot:A0A5F9UKJ4;uniprot:A0A590UJB9;uniprot:A0A590UKD0;uniprot:A0A5F9UN72;uniprot:A0A2R8YEU4;uniprot:V9HW56;uniprot:A0A2R8YE05;uniprot:K7ENT6;uniprot:A0A590UK79;uniprot:P67936;uniprot:K7ELP0;uniprot:A0A2R8YHD2;uniprot:K7EPB9;uniprot:A0A2R8Y5V9 +CPOX GeneProduct ensembl:ENSG00000080819 "" ensembl:ENSG00000080819 ncbigene:1371 hgnc.symbol:CPOX uniprot:D6RER6;uniprot:P36551 +GEMIN7 GeneProduct ensembl:ENSG00000142252 "" ensembl:ENSG00000142252 ncbigene:79760 hgnc.symbol:GEMIN7 uniprot:Q9H840 +POLD2 GeneProduct ensembl:ENSG00000106628 "" ensembl:ENSG00000106628 ncbigene:5425 hgnc.symbol:POLD2 uniprot:F8W8R3;uniprot:P49005;uniprot:C9IZD2;uniprot:C9JHC7;uniprot:H7C1B3;uniprot:A0A087WWF6;uniprot:C9JLE1 +CDKN1A / p21 GeneProduct ensembl:ENSG00000124762 "" ensembl:ENSG00000124762 ncbigene:1026 hgnc.symbol:CDKN1A uniprot:A0A024RCX5;uniprot:P38936 +ANAPC1 GeneProduct ensembl:ENSG00000153107 "" ensembl:ENSG00000153107 ncbigene:64682 hgnc.symbol:ANAPC1 uniprot:Q9H1A4;uniprot:A0A2R8YF63;uniprot:F8WAS1;uniprot:H0Y564 +PTBP2 GeneProduct ensembl:ENSG00000117569 "" ensembl:ENSG00000117569 ncbigene:58155 hgnc.symbol:PTBP2 uniprot:A0A6Q8PEZ3;uniprot:B4DI28;uniprot:Q9UKA9;uniprot:A0A6Q8PFC0;uniprot:A0A6Q8PH82;uniprot:A0A6Q8PFE6;uniprot:A0A6Q8PH43;uniprot:A0A7I2RVZ4;uniprot:A0A6Q8PFT8 +KPNA3 GeneProduct ensembl:ENSG00000102753 "" ensembl:ENSG00000102753 ncbigene:3839 hgnc.symbol:KPNA3 uniprot:H0Y4S9;uniprot:O00505;uniprot:A0A024RDV7 +NF2 GeneProduct ensembl:ENSG00000186575 "" ensembl:ENSG00000186575 ncbigene:4771 hgnc.symbol:NF2 uniprot:A0A5F9ZHA0;uniprot:A0A5K1VW66;uniprot:A0A024R1J8;uniprot:A0A024R1J9;uniprot:A0A5F9ZHD8;uniprot:P35240;uniprot:A0A024R1F6;uniprot:A0A024R1D9;uniprot:A0A024R1I0 +CHD1 GeneProduct ensembl:ENSG00000153922 "" ensembl:ENSG00000153922 ncbigene:1105 hgnc.symbol:CHD1 uniprot:H0Y8Z0;uniprot:H0Y8V4;uniprot:O14646;uniprot:A0A087WVF4 +BACE1 GeneProduct ensembl:ENSG00000186318 "" ensembl:ENSG00000186318 ncbigene:23621 hgnc.symbol:BACE1 uniprot:U3KPS1;uniprot:B7Z3Z4;uniprot:A0A7P0T924;uniprot:P56817;uniprot:Q76KP0;uniprot:B7Z3K2;uniprot:E9PJG7;uniprot:A0A024R3D5;uniprot:A0A024R3D7;uniprot:A0A024R3E8;uniprot:A0A024R3F9;uniprot:A0A7P0TAB4 +RAD23B GeneProduct ensembl:ENSG00000119318 "" ensembl:ENSG00000119318 ncbigene:5887 hgnc.symbol:RAD23B uniprot:Q5W0S5;uniprot:Q5W0S4;uniprot:P54727;uniprot:H0Y579 +AMIGO2 GeneProduct ensembl:ENSG00000139211 "" ensembl:ENSG00000139211 ncbigene:347902 hgnc.symbol:AMIGO2 uniprot:Q86SJ2;uniprot:A0A024R127 +GJA1 GeneProduct ensembl:ENSG00000152661 "" ensembl:ENSG00000152661 ncbigene:2697 hgnc.symbol:GJA1 uniprot:A0A654IBU3;uniprot:P17302 +HIPK3 GeneProduct ensembl:ENSG00000110422 "" ensembl:ENSG00000110422 ncbigene:10114 hgnc.symbol:HIPK3 uniprot:Q9H422;uniprot:E9PKD7 +NFIA / NF1-A GeneProduct ensembl:ENSG00000162599 "" ensembl:ENSG00000162599 ncbigene:4774 hgnc.symbol:NFIA uniprot:S4R308;uniprot:A0A590UJA3;uniprot:Q12857;uniprot:S4R3K4;uniprot:S4R3K5;uniprot:A0A590UK09;uniprot:B1AKN6;uniprot:S4R3W2;uniprot:B1AKN7;uniprot:A0A590UK38;uniprot:B1AKN8;uniprot:S4R3W6;uniprot:A0A590UJU2;uniprot:A0A590UK73;uniprot:A0A590UJ82;uniprot:B1AKN5;uniprot:A0A590UJ67 +TXNRD1 GeneProduct ensembl:ENSG00000198431 "" ensembl:ENSG00000198431 ncbigene:7296 hgnc.symbol:TXNRD1 uniprot:E9PKI4;uniprot:E9PLT3;uniprot:E9PQI3;uniprot:E9PKD3;uniprot:A0A0B4J225;uniprot:E9PIR7;uniprot:A0A182DWI3;uniprot:E9PIZ5;uniprot:Q16881;uniprot:E9PRI8 +SLC25A32 GeneProduct ensembl:ENSG00000164933 "" ensembl:ENSG00000164933 ncbigene:81034 hgnc.symbol:SLC25A32 uniprot:E5RFL3;uniprot:E5RGT9;uniprot:E5RGK5;uniprot:Q9H2D1 +COL3A1 GeneProduct ensembl:ENSG00000168542 "" ensembl:ENSG00000168542 ncbigene:1281 hgnc.symbol:COL3A1 uniprot:H7C435;uniprot:P02461 +GPD2 GeneProduct ensembl:ENSG00000115159 "" ensembl:ENSG00000115159 ncbigene:2820 hgnc.symbol:GPD2 uniprot:E7EM56;uniprot:E9PDK4;uniprot:P43304;uniprot:F5GYK7 +SRF GeneProduct ensembl:ENSG00000112658 "" ensembl:ENSG00000112658 ncbigene:6722 hgnc.symbol:SRF uniprot:P11831;uniprot:A0A024RD16 +HSD17B12 GeneProduct ensembl:ENSG00000149084 "" ensembl:ENSG00000149084 ncbigene:51144 hgnc.symbol:HSD17B12 uniprot:E9PI21;uniprot:A0A1B0GW85;uniprot:A0A1B0GVY6;uniprot:Q53GQ0;uniprot:A0A1B0GU83;uniprot:A0A1B0GV93;uniprot:A0A1B0GW27 +SFRS9 GeneProduct ensembl:ENSG00000111786 "" ensembl:ENSG00000111786 ncbigene:8683 hgnc.symbol:SRSF9 uniprot:S4R3G0;uniprot:H0YIB4;uniprot:Q13242 +CYP51A1 GeneProduct ensembl:ENSG00000001630 "" ensembl:ENSG00000001630 ncbigene:1595 hgnc.symbol:CYP51A1 uniprot:H7C0D0;uniprot:Q16850 +CLOCK GeneProduct ensembl:ENSG00000134852 "" ensembl:ENSG00000134852 ncbigene:9575 hgnc.symbol:CLOCK uniprot:C9JK03;uniprot:O15516 +VSNL1 GeneProduct ensembl:ENSG00000163032 "" ensembl:ENSG00000163032 ncbigene:7447 hgnc.symbol:VSNL1 uniprot:E9PE24;uniprot:P62760;uniprot:E7ER47 +VPS39 GeneProduct ensembl:ENSG00000166887 "" ensembl:ENSG00000166887 ncbigene:23339 hgnc.symbol:VPS39 uniprot:Q96JC1;uniprot:H3BTU0;uniprot:A0A024R9L9 +RAB27B GeneProduct ensembl:ENSG00000041353 "" ensembl:ENSG00000041353 ncbigene:5874 hgnc.symbol:RAB27B uniprot:K7EJ38;uniprot:K7ES41;uniprot:O00194 +FAM96A GeneProduct ensembl:ENSG00000166797 "" ensembl:ENSG00000166797 ncbigene:84191 hgnc.symbol:CIAO2A uniprot:H0YLH6;uniprot:H0YKV4;uniprot:Q9H5X1 +PDLIM7 GeneProduct ensembl:ENSG00000196923 "" ensembl:ENSG00000196923 ncbigene:9260 hgnc.symbol:PDLIM7 uniprot:D6RH06;uniprot:D6RAN1;uniprot:H7BYK4;uniprot:D6RF83;uniprot:Q9NR12 +NOTCH1 GeneProduct ensembl:ENSG00000148400 "" ensembl:ENSG00000148400 ncbigene:4851 hgnc.symbol:NOTCH1 uniprot:A0A7P0TAK8;uniprot:A0A7P0TBG2;uniprot:A0A7P0T8U6;uniprot:A0A7P0T9V1;uniprot:A0A7P0TA56;uniprot:P46531;uniprot:A0A7P0TB20;uniprot:A0A7P0T8W1;uniprot:A0A7P0Z4H9 +PTPLAD1 GeneProduct ensembl:ENSG00000074696 "" ensembl:ENSG00000074696 ncbigene:51495 hgnc.symbol:HACD3 uniprot:H3BMZ1;uniprot:H3BPZ1;uniprot:Q9P035;uniprot:H3BRL8;uniprot:H3BS72 +GRPEL2 GeneProduct ensembl:ENSG00000164284 "" ensembl:ENSG00000164284 ncbigene:134266 hgnc.symbol:GRPEL2 uniprot:Q8TAA5;uniprot:D6RGI6 +DMTF1 GeneProduct ensembl:ENSG00000135164 "" ensembl:ENSG00000135164 ncbigene:9988 hgnc.symbol:DMTF1 uniprot:F8VXY9;uniprot:J3QLW3;uniprot:C9J8Y5;uniprot:E7EPA0;uniprot:A0A1D5RMP8;uniprot:J3KRC1;uniprot:C9JLR5;uniprot:Q9Y222;uniprot:H7C388;uniprot:C9JVQ7;uniprot:C9K0L9;uniprot:C9JED5;uniprot:C9JZZ6;uniprot:J3QKU5;uniprot:J3QLN9;uniprot:C9K0K9;uniprot:C9JFR2;uniprot:C9J4F7;uniprot:C9JGT5 +LAMC2 GeneProduct ensembl:ENSG00000058085 "" ensembl:ENSG00000058085 ncbigene:3918 hgnc.symbol:LAMC2 uniprot:Q13753 +G6PD GeneProduct ensembl:ENSG00000160211 "" ensembl:ENSG00000160211 ncbigene:2539 hgnc.symbol:G6PD uniprot:E7EM57;uniprot:P11413;uniprot:E7EUI8;uniprot:E9PD92;uniprot:A0A384NL00 +CALCOCO2 GeneProduct ensembl:ENSG00000136436 "" ensembl:ENSG00000136436 ncbigene:10241 hgnc.symbol:CALCOCO2 uniprot:D6RJE7;uniprot:Q13137;uniprot:D6RF70;uniprot:D6RBI4;uniprot:D6REB0;uniprot:H0YBP4;uniprot:I3L4E1;uniprot:I3L493;uniprot:H0Y9G3;uniprot:D6RBF9 +PPP2R4 GeneProduct ensembl:ENSG00000119383 "" ensembl:ENSG00000119383 ncbigene:5524 hgnc.symbol:PTPA uniprot:Q5T949;uniprot:C9IZ76;uniprot:Q15257;uniprot:A0A804CD06;uniprot:H0Y6E5;uniprot:Q68CR8;uniprot:B7ZBP7;uniprot:H0Y562;uniprot:B7ZBP9;uniprot:A6PVN8;uniprot:B7ZBQ0;uniprot:F6WIT2;uniprot:B4DDQ6;uniprot:A6PVN5;uniprot:A6PVN6;uniprot:A6PVN7 +UHRF1 GeneProduct ensembl:ENSG00000276043 "" ensembl:ENSG00000276043 ncbigene:29128 hgnc.symbol:UHRF1 uniprot:A0A087WTW0;uniprot:A0A087WWG9;uniprot:Q96T88;uniprot:A0A087WVR3 +METTL7A GeneProduct ensembl:ENSG00000185432 "" ensembl:ENSG00000185432 ncbigene:25840 hgnc.symbol:METTL7A uniprot:Q9H8H3;uniprot:F8VQX6;uniprot:A0A024R118;uniprot:H0YI09 +HBXIP GeneProduct ensembl:ENSG00000134248 "" ensembl:ENSG00000134248 ncbigene:10542 hgnc.symbol:LAMTOR5 uniprot:E9PLX3;uniprot:R4GMU8;uniprot:A0A0C4DGV4;uniprot:O43504 +SPTLC1 GeneProduct ensembl:ENSG00000090054 "" ensembl:ENSG00000090054 ncbigene:10558 hgnc.symbol:SPTLC1 uniprot:A0A2R8Y4S0;uniprot:A0A024R277;uniprot:A0A2R8Y6A2;uniprot:A0A2R8Y763;uniprot:O15269 +TDG GeneProduct ensembl:ENSG00000139372 "" ensembl:ENSG00000139372 ncbigene:6996 hgnc.symbol:TDG uniprot:H0YH18;uniprot:Q13569;uniprot:F5H539;uniprot:G8JL98;uniprot:F5H0I7;uniprot:B4E127 +ACAA2 GeneProduct ensembl:ENSG00000167315 "" ensembl:ENSG00000167315 ncbigene:10449 hgnc.symbol:ACAA2 uniprot:K7EJ68;uniprot:A0A0B4J2A4;uniprot:K7EME0;uniprot:K7EJB1;uniprot:P42765;uniprot:K7ER88 +SLC12A4 GeneProduct ensembl:ENSG00000124067 "" ensembl:ENSG00000124067 ncbigene:6560 hgnc.symbol:SLC12A4 uniprot:J3QKM4;uniprot:J3QRE2;uniprot:J3QSF2;uniprot:Q9UP95;uniprot:I3L1N8;uniprot:I3L4N6 +TXN2 GeneProduct ensembl:ENSG00000100348 "" ensembl:ENSG00000100348 ncbigene:25828 hgnc.symbol:TXN2 uniprot:F8WDN2;uniprot:M0QXH0;uniprot:Q99757 +HMOX1 GeneProduct ensembl:ENSG00000100292 "" ensembl:ENSG00000100292 ncbigene:3162 hgnc.symbol:HMOX1 uniprot:A0A7I2V277;uniprot:Q6FH11;uniprot:A0A7I2V3M0;uniprot:A0A7I2YQL9;uniprot:P09601;uniprot:A0A7I2V3I1;uniprot:B1AHA8 +AARSD1 GeneProduct ensembl:ENSG00000108825 "" ensembl:ENSG00000108825 ncbigene:100885850 hgnc.symbol:PTGES3L-AARSD1 uniprot:L7N2F6;uniprot:Q9BTE6;uniprot:B3KSP9;uniprot:H7C054;uniprot:C9J5N1;uniprot:C9JUA3 +TMEM113 p/ ro2730 GeneProduct ensembl:ENSG00000164091 "" ensembl:ENSG00000164091 ncbigene:80335 hgnc.symbol:WDR82 uniprot:C9J355;uniprot:C9JBU3;uniprot:A0A024R333;uniprot:Q6UXN9 +E2F1 GeneProduct ensembl:ENSG00000101412 "" ensembl:ENSG00000101412 ncbigene:1869 hgnc.symbol:E2F1 uniprot:Q01094 +PPP3CA GeneProduct ensembl:ENSG00000138814 "" ensembl:ENSG00000138814 ncbigene:5530 hgnc.symbol:PPP3CA uniprot:E9PPC8;uniprot:A0A0S2Z4B5;uniprot:A0A0S2Z4C6;uniprot:E7ETC2;uniprot:E9PK68;uniprot:Q08209;uniprot:H0YAB4 +SLC38A1 GeneProduct ensembl:ENSG00000111371 "" ensembl:ENSG00000111371 ncbigene:81539 hgnc.symbol:SLC38A1 uniprot:Q9H2H9;uniprot:F8VX04;uniprot:F8VX12;uniprot:A0A024R124 +TM6SF1 GeneProduct ensembl:ENSG00000136404 "" ensembl:ENSG00000136404 ncbigene:53346 hgnc.symbol:TM6SF1 uniprot:E9PD04;uniprot:Q6P4D7;uniprot:Q8N5N8;uniprot:Q9BZW5;uniprot:H3BMK0;uniprot:H3BM84 +PSAT1 GeneProduct ensembl:ENSG00000135069 "" ensembl:ENSG00000135069 ncbigene:29968 hgnc.symbol:PSAT1 uniprot:Q9Y617;uniprot:A0A024R222;uniprot:A0A024R280 +BRPF3 GeneProduct ensembl:ENSG00000096070 "" ensembl:ENSG00000096070 ncbigene:27154 hgnc.symbol:BRPF3 uniprot:E9PJ12;uniprot:F6XDC4;uniprot:A8WI61;uniprot:Q9ULD4;uniprot:E9PSF3;uniprot:H0Y7B4;uniprot:E9PI60;uniprot:A8WI62;uniprot:H0Y7I6 +SEC23A GeneProduct ensembl:ENSG00000100934 "" ensembl:ENSG00000100934 ncbigene:10484 hgnc.symbol:SEC23A uniprot:G3V5K1;uniprot:G3V1W4;uniprot:G3V4V1;uniprot:G3V3G5;uniprot:Q15436;uniprot:F5H365;uniprot:G3V2R6;uniprot:G3V4Q2;uniprot:G3V5X8 +CDCP1 GeneProduct ensembl:ENSG00000163814 "" ensembl:ENSG00000163814 ncbigene:64866 hgnc.symbol:CDCP1 uniprot:Q9H5V8 +DNAJB1 GeneProduct ensembl:ENSG00000132002 "" ensembl:ENSG00000132002 ncbigene:3337 hgnc.symbol:DNAJB1 uniprot:M0R1D6;uniprot:Q6FHS4;uniprot:A0A7I2YQW1;uniprot:M0QZD0;uniprot:M0R128;uniprot:A0A1B0GX60;uniprot:M0R080;uniprot:M0QYT3;uniprot:M0QXK0;uniprot:A0A7I2V3K7;uniprot:P25685 +CUL4B GeneProduct ensembl:ENSG00000158290 "" ensembl:ENSG00000158290 ncbigene:8450 hgnc.symbol:CUL4B uniprot:A0A7P0Z4G9;uniprot:A0A7P0T9R8;uniprot:A0A7P0T9P5;uniprot:A0A669KAU9;uniprot:A0A7P0T954;uniprot:Q13620;uniprot:A0A7P0T9D0;uniprot:A0A669KAX4;uniprot:A0A7P0T809;uniprot:A0A804CL36;uniprot:K4DI93;uniprot:A0A7P0T8P8;uniprot:A0A7P0T9L3;uniprot:A0A7P0TAQ3;uniprot:A0A7P0Z4E4;uniprot:A0A7P0T9C8;uniprot:A0A7P0Z439;uniprot:A0A7P0T8W4;uniprot:A0A7P0TAF9;uniprot:A0A669KBG9;uniprot:A0A7P0T894 +NFIA GeneProduct ensembl:ENSG00000162599 "" ensembl:ENSG00000162599 ncbigene:4774 hgnc.symbol:NFIA uniprot:S4R308;uniprot:A0A590UJA3;uniprot:Q12857;uniprot:S4R3K4;uniprot:S4R3K5;uniprot:A0A590UK09;uniprot:B1AKN6;uniprot:S4R3W2;uniprot:B1AKN7;uniprot:A0A590UK38;uniprot:B1AKN8;uniprot:S4R3W6;uniprot:A0A590UJU2;uniprot:A0A590UK73;uniprot:A0A590UJ82;uniprot:B1AKN5;uniprot:A0A590UJ67 +CSRP1 GeneProduct ensembl:ENSG00000159176 "" ensembl:ENSG00000159176 ncbigene:1465 hgnc.symbol:CSRP1 uniprot:A0A087X134;uniprot:P21291;uniprot:E9PND2;uniprot:E9PP21;uniprot:E9PS42;uniprot:A0A384P5K2 +GALNT7 GeneProduct ensembl:ENSG00000109586 "" ensembl:ENSG00000109586 ncbigene:51809 hgnc.symbol:GALNT7 uniprot:Q86SF2;uniprot:E9PBY3;uniprot:H0YAH3;uniprot:H0YAK0 +PTPRJ GeneProduct ensembl:ENSG00000149177 "" ensembl:ENSG00000149177 ncbigene:5795 hgnc.symbol:PTPRJ uniprot:E9PJ83;uniprot:E9PPH3;uniprot:Q12913 +UBE4A GeneProduct ensembl:ENSG00000110344 "" ensembl:ENSG00000110344 ncbigene:9354 hgnc.symbol:UBE4A uniprot:B7Z7P0;uniprot:Q14139 +SYNE2 GeneProduct ensembl:ENSG00000054654 "" ensembl:ENSG00000054654 ncbigene:23224 hgnc.symbol:SYNE2 uniprot:A0A669KBH2;uniprot:G3V2Q0;uniprot:G3V5X4;uniprot:A0A669KB22;uniprot:G3V3D4;uniprot:A0A669KB61;uniprot:A0A0C4DGK3;uniprot:A0A1W2PRN9;uniprot:A0A1W2PS37;uniprot:Q8WXH0;uniprot:G3V4T3;uniprot:A0A669KBG2;uniprot:G3V5N1 +SLC25A24 GeneProduct ensembl:ENSG00000085491 "" ensembl:ENSG00000085491 ncbigene:29957 hgnc.symbol:SLC25A24 uniprot:H3BMI3;uniprot:J3KN42;uniprot:Q6NUK1;uniprot:A0A3B3IU96 +MAPK7 GeneProduct ensembl:ENSG00000166484 "" ensembl:ENSG00000166484 ncbigene:5598 hgnc.symbol:MAPK7 uniprot:S4R3I1;uniprot:C9JUK9;uniprot:J3KT50;uniprot:J3KT61;uniprot:I3L0J8;uniprot:A0A024QZ20;uniprot:Q13164 +HSDL1 GeneProduct ensembl:ENSG00000103160 "" ensembl:ENSG00000103160 ncbigene:83693 hgnc.symbol:HSDL1 uniprot:H3BT52;uniprot:H3BQI7;uniprot:H3BNH5;uniprot:Q3SXM5 +MOV10 GeneProduct ensembl:ENSG00000155363 "" ensembl:ENSG00000155363 ncbigene:4343 hgnc.symbol:MOV10 uniprot:Q5JR04;uniprot:Q9HCE1 +NARG1 GeneProduct ensembl:ENSG00000164134 "" ensembl:ENSG00000164134 ncbigene:80155 hgnc.symbol:NAA15 uniprot:A0A0B4J1W3;uniprot:Q9BXJ9;uniprot:D6RAP7 +NUCB1 GeneProduct ensembl:ENSG00000104805 "" ensembl:ENSG00000104805 ncbigene:4924 hgnc.symbol:NUCB1 uniprot:C9J3C1;uniprot:C9JBD3;uniprot:C9JKZ2;uniprot:H7BZI1;uniprot:F8WB20;uniprot:Q02818 +VEZT / vezatin GeneProduct ensembl:ENSG00000028203 "" ensembl:ENSG00000028203 ncbigene:55591 hgnc.symbol:VEZT uniprot:F8VXA0;uniprot:F8VVS3;uniprot:F8W8C2;uniprot:F8VRY3;uniprot:F8W0S0;uniprot:Q9HBM0;uniprot:F8VPN9;uniprot:F8VUB7;uniprot:F8W088;uniprot:F8VUG0;uniprot:F8W048;uniprot:F8VS43 +NCOA3 / AIB1 GeneProduct ensembl:ENSG00000124151 "" ensembl:ENSG00000124151 ncbigene:8202 hgnc.symbol:NCOA3 uniprot:Q9Y6Q9 +FSTL1 GeneProduct ensembl:ENSG00000163430 "" ensembl:ENSG00000163430 ncbigene:11167 hgnc.symbol:FSTL1 uniprot:C9J5G4;uniprot:Q12841;uniprot:H7C4W4 +THBS1 GeneProduct ensembl:ENSG00000137801 "" ensembl:ENSG00000137801 ncbigene:7057 hgnc.symbol:THBS1 uniprot:A8MZG1;uniprot:P07996 +ZEB1 / TCF8 GeneProduct ensembl:ENSG00000148516 "" ensembl:ENSG00000148516 ncbigene:6935 hgnc.symbol:ZEB1 uniprot:F6U0D0;uniprot:P37275;uniprot:H0YMD3;uniprot:F6TDF5;uniprot:H0YND9 +C1QBP GeneProduct ensembl:ENSG00000108561 "" ensembl:ENSG00000108561 ncbigene:708 hgnc.symbol:C1QBP uniprot:I3L3Q7;uniprot:I3L3B0;uniprot:A0A0G2JLC0;uniprot:Q07021 +GPAM GeneProduct ensembl:ENSG00000119927 "" ensembl:ENSG00000119927 ncbigene:57678 hgnc.symbol:GPAM uniprot:Q9HCL2;uniprot:Q5VW52 +MYLIP GeneProduct ensembl:ENSG00000007944 "" ensembl:ENSG00000007944 ncbigene:29116 hgnc.symbol:MYLIP uniprot:Q5TIA5;uniprot:Q8WY64 +SNAP29 GeneProduct ensembl:ENSG00000099940 "" ensembl:ENSG00000099940 ncbigene:9342 hgnc.symbol:SNAP29 uniprot:C9JAF7;uniprot:O95721 +AADACL1 GeneProduct ensembl:ENSG00000144959 "" ensembl:ENSG00000144959 ncbigene:57552 hgnc.symbol:NCEH1 uniprot:Q6PIU2;uniprot:A0A0A0MTJ9;uniprot:H7C046;uniprot:F8WE33 +MLSTD2 GeneProduct ensembl:ENSG00000197601 "" ensembl:ENSG00000197601 ncbigene:84188 hgnc.symbol:FAR1 uniprot:E9PPB8;uniprot:E9PNW8;uniprot:Q8WVX9 +ERG GeneProduct ensembl:ENSG00000157554 "" ensembl:ENSG00000157554 ncbigene:2078 hgnc.symbol:ERG uniprot:A8MX39;uniprot:A8MZ24;uniprot:B5MDW0;uniprot:A0A0C4DG41;uniprot:P11308 +KDELC2 GeneProduct ensembl:ENSG00000178202 "" ensembl:ENSG00000178202 ncbigene:143888 hgnc.symbol:POGLUT3 uniprot:Q7Z4H8;uniprot:H0YEM3;uniprot:A0A024R3C4 +TPM1 GeneProduct ensembl:ENSG00000140416 "" ensembl:ENSG00000140416 ncbigene:7168 hgnc.symbol:TPM1 uniprot:A0A494BZZ2;uniprot:A0A494C0V8;uniprot:A0A0K0K1I0;uniprot:A0A0S2Z4G6;uniprot:H0YKX5;uniprot:H7BYY1;uniprot:A0A494C0I0;uniprot:B7Z596;uniprot:F5H7S3;uniprot:H0YL80;uniprot:H0YK48;uniprot:H0YKP3;uniprot:P09493;uniprot:H0YLS7;uniprot:A0A087WTJ7;uniprot:H0YL42;uniprot:A0A024R5W6;uniprot:D9YZV4;uniprot:Q6ZN40;uniprot:D9YZV5;uniprot:H0YKJ4;uniprot:D9YZV7;uniprot:H0YN06 +SFXN1 GeneProduct ensembl:ENSG00000164466 "" ensembl:ENSG00000164466 ncbigene:94081 hgnc.symbol:SFXN1 uniprot:S4R2X2;uniprot:D6RFI0;uniprot:D6RDG7;uniprot:Q9H9B4;uniprot:D6RAE9;uniprot:H0Y9J5 +IPO4 GeneProduct ensembl:ENSG00000196497 "" ensembl:ENSG00000196497 ncbigene:79711 hgnc.symbol:IPO4 uniprot:H0YMR4;uniprot:H0YN14;uniprot:H0YLV0;uniprot:H0YKG5;uniprot:H0YK93;uniprot:H0YL92;uniprot:H0YN07;uniprot:Q8TEX9 +ARL2 GeneProduct ensembl:ENSG00000110025 "" ensembl:ENSG00000110025 ncbigene:29907 hgnc.symbol:SNX15 uniprot:E9PR81;uniprot:E9PMW6;uniprot:E9PNI5;uniprot:E5KQS5;uniprot:E9PK26;uniprot:Q9NRS6 +NM_032121 GeneProduct ensembl:ENSG00000102158 "" ensembl:ENSG00000102158 ncbigene:84061 hgnc.symbol:MAGT1 uniprot:A0A087WU53;uniprot:Q9H0U3 +EIF4E GeneProduct ensembl:ENSG00000151247 "" ensembl:ENSG00000151247 ncbigene:1977 hgnc.symbol:EIF4E uniprot:D6RBW1;uniprot:D6RFJ3;uniprot:X5D7E3;uniprot:P06730;uniprot:H0Y8J7 +AP3D1 GeneProduct ensembl:ENSG00000065000 "" ensembl:ENSG00000065000 ncbigene:8943 hgnc.symbol:AP3D1 uniprot:A0A2R8Y4J3;uniprot:A0A087WYN6;uniprot:K7ELX8;uniprot:A0A2R8YCY8;uniprot:O14617;uniprot:K7ERW8 +GSTM4 GeneProduct ensembl:ENSG00000168765 "" ensembl:ENSG00000168765 ncbigene:2948 hgnc.symbol:GSTM4 uniprot:Q03013;uniprot:A6NNT0;uniprot:A0A140VKE3 +LRP1 GeneProduct ensembl:ENSG00000123384 "" ensembl:ENSG00000123384 ncbigene:4035 hgnc.symbol:LRP1 uniprot:Q6PJ72;uniprot:H0YJ88;uniprot:Q07954;uniprot:H0YJI8;uniprot:Q7Z7K9 +NM_018211 GeneProduct ensembl:ENSG00000162437 "" ensembl:ENSG00000162437 ncbigene:55225 hgnc.symbol:RAVER2 uniprot:Q9HCJ3;uniprot:E9PE10 +GFM1 GeneProduct ensembl:ENSG00000168827 "" ensembl:ENSG00000168827 ncbigene:85476 hgnc.symbol:GFM1 uniprot:H7C5M4;uniprot:C9JA25;uniprot:Q96RP9;uniprot:F8WAU4;uniprot:C9IZ01;uniprot:E5KND5 +CAMTA1 GeneProduct ensembl:ENSG00000171735 "" ensembl:ENSG00000171735 ncbigene:23261 hgnc.symbol:CAMTA1 uniprot:H0YJR7;uniprot:A0A0C4DGL0;uniprot:G3V297;uniprot:Q9Y6Y1;uniprot:H0YJK7;uniprot:H0YJG5;uniprot:H0YJY7;uniprot:H0YJV1 +EZH2 / Enx-1 GeneProduct ensembl:ENSG00000106462 "" ensembl:ENSG00000106462 ncbigene:2146 hgnc.symbol:EZH2 uniprot:A0A090N8E9;uniprot:Q15910;uniprot:A0A804HJH1;uniprot:G3XAL2;uniprot:E9PDH6;uniprot:S4S3R8;uniprot:A0A804HLB8 +EIF2C3 GeneProduct ensembl:ENSG00000126070 "" ensembl:ENSG00000126070 ncbigene:192669 hgnc.symbol:AGO3 uniprot:Q9H9G7;uniprot:A0A0U1RR19;uniprot:Q5TA56 +PDE3A GeneProduct ensembl:ENSG00000172572 "" ensembl:ENSG00000172572 ncbigene:5139 hgnc.symbol:PDE3A uniprot:Q14432 +PAFAH1B2 GeneProduct ensembl:ENSG00000168092 "" ensembl:ENSG00000168092 ncbigene:5049 hgnc.symbol:PAFAH1B2 uniprot:J3KNE3;uniprot:V9HW44;uniprot:P68402 +ATG9A GeneProduct ensembl:ENSG00000198925 "" ensembl:ENSG00000198925 ncbigene:79065 hgnc.symbol:ATG9A uniprot:C9JFV2;uniprot:C9JS65;uniprot:F2Z3I6;uniprot:C9JD65;uniprot:C9JXG2;uniprot:C9JDK4;uniprot:C9JX27;uniprot:C9IYZ9;uniprot:C9JKV7;uniprot:H7C1G6;uniprot:Q7Z3C6;uniprot:A0A024R438 +HES1 GeneProduct ensembl:ENSG00000114315 "" ensembl:ENSG00000114315 ncbigene:3280 hgnc.symbol:HES1 uniprot:Q14469 +ELMOD2 GeneProduct ensembl:ENSG00000179387 "" ensembl:ENSG00000179387 ncbigene:255520 hgnc.symbol:ELMOD2 uniprot:Q8IZ81;uniprot:D6RJB5;uniprot:D6RBS5;uniprot:D6RHX2;uniprot:V9GY58 +CORO1C GeneProduct ensembl:ENSG00000110880 "" ensembl:ENSG00000110880 ncbigene:23603 hgnc.symbol:CORO1C uniprot:F8VRE9;uniprot:F8VSA4;uniprot:F8VTT6;uniprot:A0A024RBI5;uniprot:B4E3S0;uniprot:F8VVB7;uniprot:F8VUX3;uniprot:F8W1H8;uniprot:Q9ULV4;uniprot:F8VV53;uniprot:H0YHL7 +PISD GeneProduct ensembl:ENSG00000241878 "" ensembl:ENSG00000241878 ncbigene:23761 hgnc.symbol:PISD uniprot:A0A024R1K5;uniprot:B1AKM9;uniprot:H0Y7P7;uniprot:F8WCS6;uniprot:B1AKM6;uniprot:B1AKM8;uniprot:Q9UG56;uniprot:B1AKN0 +Ezh2 GeneProduct ensembl:ENSG00000106462 "" ensembl:ENSG00000106462 ncbigene:2146 hgnc.symbol:EZH2 uniprot:A0A090N8E9;uniprot:Q15910;uniprot:A0A804HJH1;uniprot:G3XAL2;uniprot:E9PDH6;uniprot:S4S3R8;uniprot:A0A804HLB8 +RBMS1 GeneProduct ensembl:ENSG00000153250 "" ensembl:ENSG00000153250 ncbigene:5937 hgnc.symbol:RBMS1 uniprot:E7EPF2;uniprot:P29558;uniprot:E7ETU5 +RAB34 GeneProduct ensembl:ENSG00000109113 "" ensembl:ENSG00000109113 ncbigene:83871 hgnc.symbol:RAB34 uniprot:A0A024QZ68;uniprot:A0A1B0GTQ2;uniprot:V9GY61;uniprot:K7EIF2;uniprot:H7C0Y7;uniprot:E7ES60;uniprot:A0A1C7CYW6;uniprot:A0A1B0GWB1;uniprot:P0DI83;uniprot:C9JY26;uniprot:K7EJW7;uniprot:Q96PJ7;uniprot:A0A1B0GVI6;uniprot:Q9BZG1;uniprot:J3QLC6;uniprot:C9JBG0 +KRAS GeneProduct ensembl:ENSG00000133703 "" ensembl:ENSG00000133703 ncbigene:3845 hgnc.symbol:KRAS uniprot:G3V4K2;uniprot:A0A024RAV5;uniprot:P01116;uniprot:L7RSL8;uniprot:G3V5T7 +BRWD2 GeneProduct ensembl:ENSG00000120008 "" ensembl:ENSG00000120008 ncbigene:55717 hgnc.symbol:WDR11 uniprot:S4R3P9;uniprot:Q9BZH6;uniprot:S4R451;uniprot:S4R3Z0 +FRG1 GeneProduct ensembl:ENSG00000109536 "" ensembl:ENSG00000109536 ncbigene:2483 hgnc.symbol:FRG1 uniprot:E9PI42;uniprot:E9PRR7;uniprot:E9PLY7;uniprot:Q14331;uniprot:J3KSQ7 +ERBB3 GeneProduct ensembl:ENSG00000065361 "" ensembl:ENSG00000065361 ncbigene:2065 hgnc.symbol:ERBB3 uniprot:F8VRL0;uniprot:B4DGQ7;uniprot:F8VW48;uniprot:A0A2R8Y6T4;uniprot:F8VRI5;uniprot:O75812;uniprot:P21860;uniprot:B3KWG5;uniprot:F8VYK4 +MRC2 GeneProduct ensembl:ENSG00000011028 "" ensembl:ENSG00000011028 ncbigene:9902 hgnc.symbol:MRC2 uniprot:J3KRF1;uniprot:J3QQZ6;uniprot:Q9UBG0;uniprot:E7EME3 +THBS1 GeneProduct ensembl:ENSG00000137801 "" ensembl:ENSG00000137801 ncbigene:7057 hgnc.symbol:THBS1 uniprot:A8MZG1;uniprot:P07996 +EHMT2 GeneProduct ensembl:ENSG00000204371 "" ensembl:ENSG00000204371 ncbigene:10919 hgnc.symbol:EHMT2 uniprot:H0Y4K5;uniprot:A0A024RCN9;uniprot:A2ABF9;uniprot:Q96KQ7;uniprot:A2ABF8 +STRN GeneProduct ensembl:ENSG00000115808 "" ensembl:ENSG00000115808 ncbigene:6801 hgnc.symbol:STRN uniprot:O43815 +CAND1 GeneProduct ensembl:ENSG00000111530 "" ensembl:ENSG00000111530 ncbigene:55832 hgnc.symbol:CAND1 uniprot:H0YH27;uniprot:Q86VP6;uniprot:A0A0C4DGH5;uniprot:F5H6I6 +PGM1 GeneProduct ensembl:ENSG00000079739 "" ensembl:ENSG00000079739 ncbigene:5236 hgnc.symbol:PGM1 uniprot:P36871;uniprot:A0A3B3ITK7 +TYMS GeneProduct ensembl:ENSG00000176890 "" ensembl:ENSG00000176890 ncbigene:7298 hgnc.symbol:TYMS uniprot:P04818;uniprot:Q53Y97 +PGRMC1 GeneProduct ensembl:ENSG00000101856 "" ensembl:ENSG00000101856 ncbigene:10857 hgnc.symbol:PGRMC1 uniprot:Q6IB11;uniprot:O00264 +ARID1A GeneProduct ensembl:ENSG00000117713 "" ensembl:ENSG00000117713 ncbigene:8289 hgnc.symbol:ARID1A uniprot:A0A1B0GVT5;uniprot:O14497;uniprot:A0A1B0GTU5;uniprot:E9PQW6;uniprot:H0YEW5;uniprot:H0Y488;uniprot:H0YCU6 +SRPRB GeneProduct ensembl:ENSG00000144867 "" ensembl:ENSG00000144867 ncbigene:58477 hgnc.symbol:SRPRB uniprot:Q549N5;uniprot:C9J5Z8;uniprot:Q9Y5M8;uniprot:H7C4H2 +SSNA1 GeneProduct ensembl:ENSG00000176101 "" ensembl:ENSG00000176101 ncbigene:8636 hgnc.symbol:SSNA1 uniprot:O43805;uniprot:A0A024R8G6;uniprot:A0A087WV26 +ATAD3B GeneProduct ensembl:ENSG00000160072 "" ensembl:ENSG00000160072 ncbigene:83858 hgnc.symbol:ATAD3B uniprot:A0A5K1VW56;uniprot:Q5T9A4 +MYO1E GeneProduct ensembl:ENSG00000157483 "" ensembl:ENSG00000157483 ncbigene:4643 hgnc.symbol:MYO1E uniprot:Q12965;uniprot:H0YN00;uniprot:H0YLE5;uniprot:H0YNB0;uniprot:H0YLJ4;uniprot:H0YNQ8;uniprot:Q4KMR3 +GALNT1 GeneProduct ensembl:ENSG00000141429 "" ensembl:ENSG00000141429 ncbigene:2589 hgnc.symbol:GALNT1 uniprot:K7EK46;uniprot:K7EJV8;uniprot:Q10472;uniprot:A0A024RC48 +ANP32B GeneProduct ensembl:ENSG00000136938 "" ensembl:ENSG00000136938 ncbigene:10541 hgnc.symbol:ANP32B uniprot:Q92688 +SNX15 GeneProduct ensembl:ENSG00000110025 "" ensembl:ENSG00000110025 ncbigene:29907 hgnc.symbol:SNX15 uniprot:E9PR81;uniprot:E9PMW6;uniprot:E9PNI5;uniprot:E5KQS5;uniprot:E9PK26;uniprot:Q9NRS6 +PHLDB2 GeneProduct ensembl:ENSG00000144824 "" ensembl:ENSG00000144824 ncbigene:90102 hgnc.symbol:PHLDB2 uniprot:E9PGF6;uniprot:A0A1W2PQ63;uniprot:A0A1W2PRJ2;uniprot:E9PFQ4;uniprot:G5E9V3;uniprot:Q86SQ0;uniprot:E9PDY7;uniprot:A0A1W2PRT1 +PWP1 GeneProduct ensembl:ENSG00000136045 "" ensembl:ENSG00000136045 ncbigene:11137 hgnc.symbol:PWP1 uniprot:A0A024RBH5;uniprot:F8VZ56;uniprot:Q13610;uniprot:B4DJV5 +CSF1 / MCSF GeneProduct ensembl:ENSG00000184371 "" ensembl:ENSG00000184371 ncbigene:1435 hgnc.symbol:CSF1 uniprot:E9PJA2;uniprot:E9PQ08;uniprot:E9PKP4;uniprot:H7BY18;uniprot:P09603 +MTRR GeneProduct ensembl:ENSG00000124275 "" ensembl:ENSG00000124275 ncbigene:4552 hgnc.symbol:MTRR uniprot:D6RAY3;uniprot:D6RGC7;uniprot:H0Y8S9;uniprot:D6RAZ2;uniprot:H0Y9D5;uniprot:D6RIS8;uniprot:Q9UBK8;uniprot:H0Y963;uniprot:A0A3P9MRF3;uniprot:H0Y9Q0;uniprot:D6RF21 +ALK4 GeneProduct ensembl:ENSG00000135503 "" ensembl:ENSG00000135503 ncbigene:91 hgnc.symbol:ACVR1B uniprot:F5H5Q2;uniprot:P36896 +LRRC8A GeneProduct ensembl:ENSG00000136802 "" ensembl:ENSG00000136802 ncbigene:56262 hgnc.symbol:LRRC8A uniprot:Q8IWT6;uniprot:A0A024R892 +SEC24A GeneProduct ensembl:ENSG00000113615 "" ensembl:ENSG00000113615 ncbigene:10802 hgnc.symbol:SEC24A uniprot:O95486;uniprot:H0Y9J6 +PKM2 GeneProduct ensembl:ENSG00000067225 "" ensembl:ENSG00000067225 ncbigene:5315 hgnc.symbol:PKM uniprot:P14618;uniprot:H3BN34;uniprot:H3BUW1;uniprot:B4DNK4;uniprot:H3BQZ3;uniprot:A0A804F6T5;uniprot:H3BT25;uniprot:H3BU13;uniprot:H3BQ34;uniprot:A0A024R5Z9;uniprot:H3BTJ2;uniprot:A0A804F729;uniprot:H3BTN5;uniprot:V9HWB8 +TNFAIP2 GeneProduct ensembl:ENSG00000185215 "" ensembl:ENSG00000185215 ncbigene:7127 hgnc.symbol:TNFAIP2 uniprot:H0YM45;uniprot:H0YKR7;uniprot:H0YKY9;uniprot:H0YKI8;uniprot:H0YL88;uniprot:Q03169;uniprot:H0YLC0 +GRIA2 GeneProduct ensembl:ENSG00000120251 "" ensembl:ENSG00000120251 ncbigene:2891 hgnc.symbol:GRIA2 uniprot:D6R9Z0;uniprot:D6RFM6;uniprot:P42262;uniprot:F8W7L6;uniprot:D6RBV7;uniprot:D6RDX5;uniprot:H0Y972 +YWHAQ GeneProduct ensembl:ENSG00000134308 "" ensembl:ENSG00000134308 ncbigene:10971 hgnc.symbol:YWHAQ uniprot:P27348;uniprot:E9PG15 +NUFIP2 GeneProduct ensembl:ENSG00000108256 "" ensembl:ENSG00000108256 ncbigene:57532 hgnc.symbol:NUFIP2 uniprot:Q7Z417 +SLC25A13 GeneProduct ensembl:ENSG00000004864 "" ensembl:ENSG00000004864 ncbigene:10165 hgnc.symbol:SLC25A13 uniprot:R4GN64;uniprot:Q9UJS0 +ATP6V0E GeneProduct ensembl:ENSG00000113732 "" ensembl:ENSG00000113732 ncbigene:8992 hgnc.symbol:ATP6V0E1 uniprot:O15342;uniprot:J3KN48;uniprot:E5RHL5 +RDH10 GeneProduct ensembl:ENSG00000121039 "" ensembl:ENSG00000121039 ncbigene:157506 hgnc.symbol:RDH10 uniprot:Q8IZV5;uniprot:E5RHJ9;uniprot:A0A024R7X6;uniprot:E5RK48 +PLK1 GeneProduct ensembl:ENSG00000166851 "" ensembl:ENSG00000166851 ncbigene:5347 hgnc.symbol:PLK1 uniprot:P53350;uniprot:I3L387;uniprot:I3L2H5;uniprot:I3L309 +TP53INP1 GeneProduct ensembl:ENSG00000164938 "" ensembl:ENSG00000164938 ncbigene:94241 hgnc.symbol:TP53INP1 uniprot:A0A024R9C8;uniprot:Q96A56 +NXN GeneProduct ensembl:ENSG00000167693 "" ensembl:ENSG00000167693 ncbigene:64359 hgnc.symbol:NXN uniprot:Q6DKJ4;uniprot:I3L4V6;uniprot:A0A0C4DGI2 +RB1 GeneProduct ensembl:ENSG00000139687 "" ensembl:ENSG00000139687 ncbigene:5925 hgnc.symbol:RB1 uniprot:A0A3B3IS71;uniprot:Q92728;uniprot:A0A024RDV3;uniprot:A0A2R8YFL6;uniprot:A0A2R8Y743;uniprot:P06400 +TMEM41B GeneProduct ensembl:ENSG00000166471 "" ensembl:ENSG00000166471 ncbigene:440026 hgnc.symbol:TMEM41B uniprot:E9PJ42;uniprot:Q5BJD5 +COL1A1 GeneProduct ensembl:ENSG00000108821 "" ensembl:ENSG00000108821 ncbigene:1277 hgnc.symbol:COL1A1 uniprot:I3L3H7;uniprot:P02452 +MAP2K1IP1 GeneProduct ensembl:ENSG00000109270 "" ensembl:ENSG00000109270 ncbigene:8649 hgnc.symbol:LAMTOR3 uniprot:Q9UHA4 +GNL3L GeneProduct ensembl:ENSG00000130119 "" ensembl:ENSG00000130119 ncbigene:54552 hgnc.symbol:GNL3L uniprot:A0A6I8PL80;uniprot:A0A6I8PL58;uniprot:A0A6I8PL53;uniprot:A0A6I8PS19;uniprot:Q9NVN8;uniprot:A0A024R9Y6 +SLC38A5 GeneProduct ensembl:ENSG00000017483 "" ensembl:ENSG00000017483 ncbigene:92745 hgnc.symbol:SLC38A5 uniprot:A0A087WZF9;uniprot:C9JWG4;uniprot:Q8WUX1;uniprot:A0A024QYY0;uniprot:C9JJU1;uniprot:C9JMY2;uniprot:C9JHH7;uniprot:C9JNK4 +PTMA GeneProduct ensembl:ENSG00000187514 "" ensembl:ENSG00000187514 ncbigene:5757 hgnc.symbol:PTMA uniprot:F8WCE8;uniprot:H7C2N1;uniprot:B8ZZA1;uniprot:B8ZZW7;uniprot:B8ZZQ6;uniprot:P06454;uniprot:Q53S24;uniprot:H7C031 +ANKFY1 GeneProduct ensembl:ENSG00000185722 "" ensembl:ENSG00000185722 ncbigene:51479 hgnc.symbol:ANKFY1 uniprot:K7EPT2;uniprot:Q9P2R3;uniprot:I3L1Z9;uniprot:I3L3P8 +DOCK5 GeneProduct ensembl:ENSG00000147459 "" ensembl:ENSG00000147459 ncbigene:80005 hgnc.symbol:DOCK5 uniprot:Q9H7D0;uniprot:H0Y7N4;uniprot:B9A015;uniprot:H0YB14 +POLE4 GeneProduct ensembl:ENSG00000115350 "" ensembl:ENSG00000115350 ncbigene:56655 hgnc.symbol:POLE4 uniprot:Q9NR33 +TMEM43 GeneProduct ensembl:ENSG00000170876 "" ensembl:ENSG00000170876 ncbigene:79188 hgnc.symbol:TMEM43 uniprot:F8WDL3;uniprot:Q9BTV4;uniprot:A0A024R2F9 +SLC9A3R2 GeneProduct ensembl:ENSG00000065054 "" ensembl:ENSG00000065054 ncbigene:9351 hgnc.symbol:SLC9A3R2 uniprot:H3BUQ9;uniprot:H3BMF5;uniprot:Q15599;uniprot:H3BQS0;uniprot:H3BN50 +BET1 GeneProduct ensembl:ENSG00000105829 "" ensembl:ENSG00000105829 ncbigene:10282 hgnc.symbol:BET1 uniprot:O15155;uniprot:Q53XK0;uniprot:A0A3B3IU16;uniprot:H7C1N3;uniprot:Q68DU7;uniprot:C9JTT8 +LAMC1 GeneProduct ensembl:ENSG00000135862 "" ensembl:ENSG00000135862 ncbigene:3915 hgnc.symbol:LAMC1 uniprot:P11047;uniprot:R4GNC7 +SLC7A6 GeneProduct ensembl:ENSG00000103064 "" ensembl:ENSG00000103064 ncbigene:9057 hgnc.symbol:SLC7A6 uniprot:H3BUR2;uniprot:H3BSV7;uniprot:E7EPZ8;uniprot:H3BSB6;uniprot:J3QL60;uniprot:A0A024R719;uniprot:H3BPV6;uniprot:H3BRZ8;uniprot:H3BNF5;uniprot:Q92536;uniprot:H3BUA4;uniprot:H3BPK5 +ZNF294 GeneProduct ensembl:ENSG00000198862 "" ensembl:ENSG00000198862 ncbigene:26046 hgnc.symbol:LTN1 uniprot:H7BYG8;uniprot:O94822;uniprot:S4R3T2 +IGF2BP1 / IMP-1 GeneProduct ensembl:ENSG00000159217 "" ensembl:ENSG00000159217 ncbigene:10642 hgnc.symbol:IGF2BP1 uniprot:Q9NZI8 +SNX6 GeneProduct ensembl:ENSG00000129515 "" ensembl:ENSG00000129515 ncbigene:58533 hgnc.symbol:SNX6 uniprot:G3V2U1;uniprot:G3V4Z5;uniprot:G3V5U2;uniprot:H0YJF8;uniprot:Q9UNH7;uniprot:G3V589;uniprot:G3V5X9;uniprot:A0A0A0MRI2 +AP3B1 GeneProduct ensembl:ENSG00000132842 "" ensembl:ENSG00000132842 ncbigene:8546 hgnc.symbol:AP3B1 uniprot:H0YBD0;uniprot:O00203;uniprot:A0A0S2Z5J4;uniprot:A0A0S2Z4Z4 +COMMD9 GeneProduct ensembl:ENSG00000110442 "" ensembl:ENSG00000110442 ncbigene:29099 hgnc.symbol:COMMD9 uniprot:E9PJ95;uniprot:Q53FR9;uniprot:Q9P000 +CCND1 / Cyclin D1 GeneProduct ensembl:ENSG00000110092 "" ensembl:ENSG00000110092 ncbigene:595 hgnc.symbol:CCND1 uniprot:P24385;uniprot:Q6FI00;uniprot:F5H437 +FGF2 GeneProduct ensembl:ENSG00000138685 "" ensembl:ENSG00000138685 ncbigene:2247 hgnc.symbol:FGF2 uniprot:A0A0A0MQV6;uniprot:D9ZGF5;uniprot:P09038 +LYCAT GeneProduct ensembl:ENSG00000172954 "" ensembl:ENSG00000172954 ncbigene:253558 hgnc.symbol:LCLAT1 uniprot:Q6UWP7;uniprot:C9J6F4;uniprot:C9JA02;uniprot:C9K0C3;uniprot:F8WEY2;uniprot:C9JMW2;uniprot:C9JUV9;uniprot:C9J5S5;uniprot:C9JXY8 +NRAS GeneProduct ensembl:ENSG00000009307 "" ensembl:ENSG00000009307 ncbigene:7812 hgnc.symbol:CSDE1 uniprot:E9PLT0;uniprot:A0A024R0E2;uniprot:E9PJK7;uniprot:A0A1Y8EMC9;uniprot:E9PLD4;uniprot:E9PNG3;uniprot:O75534;uniprot:A0A024R0K2;uniprot:E9PKN4 +COIL GeneProduct ensembl:ENSG00000121058 "" ensembl:ENSG00000121058 ncbigene:8161 hgnc.symbol:COIL uniprot:P38432;uniprot:I3L369 +BACH1 GeneProduct ensembl:ENSG00000156273 "" ensembl:ENSG00000156273 ncbigene:100379661;ncbigene:571 hgnc.symbol:BACH1 uniprot:C9JMP6;uniprot:F8VZL7;uniprot:H7C4B6;uniprot:C9IYH8;uniprot:M0QZP0;uniprot:O14867;uniprot:C9IYR0 +SLC1A4 GeneProduct ensembl:ENSG00000115902 "" ensembl:ENSG00000115902 ncbigene:6509 hgnc.symbol:SLC1A4 uniprot:P43007 +TBCA GeneProduct ensembl:ENSG00000171530 "" ensembl:ENSG00000171530 ncbigene:6902 hgnc.symbol:TBCA uniprot:E5RIW3;uniprot:E5RIX8;uniprot:A0A494C144;uniprot:E5RHG6;uniprot:E5RJD8;uniprot:E5RJM1;uniprot:O75347;uniprot:Q6FGD7 +LAMC1 / laminin gamma GeneProduct ensembl:ENSG00000135862 "" ensembl:ENSG00000135862 ncbigene:3915 hgnc.symbol:LAMC1 uniprot:P11047;uniprot:R4GNC7 +NM_014445 GeneProduct ensembl:ENSG00000120742 "" ensembl:ENSG00000120742 ncbigene:27230 hgnc.symbol:SERP1 uniprot:C9JUH5;uniprot:C9JSB0;uniprot:Q9Y6X1 +LPL GeneProduct ensembl:ENSG00000175445 "" ensembl:ENSG00000175445 ncbigene:4023 hgnc.symbol:LPL uniprot:A0A3B3IT60;uniprot:P06858;uniprot:E5RJZ4;uniprot:A0A1B1RVA9;uniprot:E5RHN7;uniprot:E5RJI0;uniprot:E7EW14 +KIAA1618 GeneProduct ensembl:ENSG00000180843 "" +P4HA2 GeneProduct ensembl:ENSG00000072682 "" ensembl:ENSG00000072682 ncbigene:8974 hgnc.symbol:P4HA2 uniprot:C9JCP0;uniprot:E7EPI9;uniprot:C9JFJ1;uniprot:C9JN43;uniprot:O15460;uniprot:C9JX45;uniprot:E7ENX0;uniprot:A8MXE0;uniprot:C9JIG4;uniprot:E7ERI1 +CDK6 GeneProduct ensembl:ENSG00000105810 "" ensembl:ENSG00000105810 ncbigene:1021 hgnc.symbol:CDK6 uniprot:Q00534 +ABHD10 GeneProduct ensembl:ENSG00000144827 "" ensembl:ENSG00000144827 ncbigene:55347 hgnc.symbol:ABHD10 uniprot:F8WBQ6;uniprot:F8WBJ5;uniprot:Q9NUJ1 +SLC4A10 GeneProduct ensembl:ENSG00000144290 "" ensembl:ENSG00000144290 ncbigene:57282 hgnc.symbol:SLC4A10 uniprot:E7EW28;uniprot:C9J240;uniprot:F8WDX9;uniprot:Q6U841 +TMED3 GeneProduct ensembl:ENSG00000166557 "" ensembl:ENSG00000166557 ncbigene:23423 hgnc.symbol:TMED3 uniprot:G3V1J9;uniprot:Q9Y3Q3;uniprot:F5H4M7;uniprot:A0A140VKD1 +SLC25A1 GeneProduct ensembl:ENSG00000100075 "" ensembl:ENSG00000100075 ncbigene:6576 hgnc.symbol:SLC25A1 uniprot:P53007;uniprot:B4DP62 +FADS2 GeneProduct ensembl:ENSG00000134824 "" ensembl:ENSG00000134824 ncbigene:9415 hgnc.symbol:FADS2 uniprot:O95864;uniprot:E5RGD8;uniprot:E5RGZ5;uniprot:E5RHL3 +ABCG2 GeneProduct ensembl:ENSG00000118777 "" ensembl:ENSG00000118777 ncbigene:9429 hgnc.symbol:ABCG2 uniprot:A1LUE4;uniprot:Q9UNQ0;uniprot:F8S0F2 +RQCD1 GeneProduct ensembl:ENSG00000144580 "" ensembl:ENSG00000144580 ncbigene:9125 hgnc.symbol:CNOT9 uniprot:H7C0W0;uniprot:D5MQE1;uniprot:F8WBZ6;uniprot:F8WCV7;uniprot:Q92600 +RCN2 GeneProduct ensembl:ENSG00000117906 "" ensembl:ENSG00000117906 ncbigene:5955 hgnc.symbol:RCN2 uniprot:H0YL43;uniprot:Q14257;uniprot:A8MXP8 +GFPT1 GeneProduct ensembl:ENSG00000198380 "" ensembl:ENSG00000198380 ncbigene:2673 hgnc.symbol:GFPT1 uniprot:Q06210;uniprot:A0A6I8PRT6;uniprot:A0A6I8PTT9;uniprot:A0A6I8PRN4 +CHMP2A GeneProduct ensembl:ENSG00000130724 "" ensembl:ENSG00000130724 ncbigene:27243 hgnc.symbol:CHMP2A uniprot:M0R1T5;uniprot:O43633;uniprot:A0A024R4S0;uniprot:M0QXX8;uniprot:M0R1L7 +CDK6 GeneProduct ensembl:ENSG00000105810 "" ensembl:ENSG00000105810 ncbigene:1021 hgnc.symbol:CDK6 uniprot:Q00534 +PPP1R7 GeneProduct ensembl:ENSG00000115685 "" ensembl:ENSG00000115685 ncbigene:5510 hgnc.symbol:PPP1R7 uniprot:C9J177;uniprot:C9JRC4;uniprot:B5MBZ8;uniprot:H7C3Q5;uniprot:H7C118;uniprot:C9JD73;uniprot:Q15435;uniprot:A0A140VK83;uniprot:H7C003 +SLC12A2 GeneProduct ensembl:ENSG00000064651 "" ensembl:ENSG00000064651 ncbigene:6558 hgnc.symbol:SLC12A2 uniprot:G3XAL9;uniprot:P55011;uniprot:Q53ZR1 +MRPL20 GeneProduct ensembl:ENSG00000242485 "" ensembl:ENSG00000242485 ncbigene:55052 hgnc.symbol:MRPL20 uniprot:Q9BYC9;uniprot:I3L2X1 +CEBPB GeneProduct ensembl:ENSG00000172216 "" ensembl:ENSG00000172216 ncbigene:1051 hgnc.symbol:CEBPB uniprot:P17676 +IGF2R GeneProduct ensembl:ENSG00000197081 "" ensembl:ENSG00000197081 ncbigene:3482 hgnc.symbol:IGF2R uniprot:A0A7I2YQS7;uniprot:A0A7I2V657;uniprot:A0A7I2V381;uniprot:P11717;uniprot:S4R328 +CTSC GeneProduct ensembl:ENSG00000109861 "" ensembl:ENSG00000109861 ncbigene:1075 hgnc.symbol:CTSC uniprot:P53634;uniprot:A0A7I2V3A2;uniprot:A0A7I2V6E3;uniprot:A0A7I2V3A6;uniprot:A0A7I2V5C5;uniprot:A0A7I2YQ96;uniprot:A0A7I2V592;uniprot:A0A7I2YQT5;uniprot:A0A7I2V4Z3;uniprot:H0YCY8;uniprot:A0A7I2V2V5;uniprot:A0A7I2V466;uniprot:A0A7I2V2Q8;uniprot:A0A7I2V3M6;uniprot:A0A7I2V5L5;uniprot:A0A7I2V5J2;uniprot:A0A7I2V2F3;uniprot:H0YDA2 +CDKAL1 GeneProduct ensembl:ENSG00000145996 "" ensembl:ENSG00000145996 ncbigene:54901 hgnc.symbol:CDKAL1 uniprot:Q5VV42 +CDK5RAP1 GeneProduct ensembl:ENSG00000101391 "" ensembl:ENSG00000101391 ncbigene:51654 hgnc.symbol:CDK5RAP1 uniprot:Q96SZ6;uniprot:A0A0S2Z5J9;uniprot:H0Y721;uniprot:A0A0S2Z592 +POLR2C GeneProduct ensembl:ENSG00000102978 "" ensembl:ENSG00000102978 ncbigene:5432 hgnc.symbol:POLR2C uniprot:H3BRR2;uniprot:P19387;uniprot:Q6FGR6 +CYP1B1 GeneProduct ensembl:ENSG00000138061 "" ensembl:ENSG00000138061 ncbigene:1545 hgnc.symbol:CYP1B1 uniprot:A0A087WUQ7;uniprot:A0A087WW26;uniprot:Q16678 +CXCL12 GeneProduct ensembl:ENSG00000107562 "" ensembl:ENSG00000107562 ncbigene:6387 hgnc.symbol:CXCL12 uniprot:P48061 +TGFBR2 GeneProduct ensembl:ENSG00000163513 "" ensembl:ENSG00000163513 ncbigene:7048 hgnc.symbol:TGFBR2 uniprot:D2JYI1;uniprot:P37173;uniprot:A3QNQ0 +PRKCI GeneProduct ensembl:ENSG00000163558 "" ensembl:ENSG00000163558 ncbigene:5584 hgnc.symbol:PRKCI uniprot:P41743 +PDCD4 GeneProduct ensembl:ENSG00000150593 "" ensembl:ENSG00000150593 ncbigene:27250 hgnc.symbol:PDCD4 uniprot:Q53EL6;uniprot:Q5VZS7 +DSG2 GeneProduct ensembl:ENSG00000046604 "" ensembl:ENSG00000046604 ncbigene:1829 hgnc.symbol:DSG2 uniprot:A0A804HJQ3;uniprot:J3KSI6;uniprot:Q14126;uniprot:A0A804HIA2;uniprot:A0A804HLK9;uniprot:A0A804HJ09 +MRPS24 GeneProduct ensembl:ENSG00000062582 "" ensembl:ENSG00000062582 ncbigene:64951 hgnc.symbol:MRPS24 uniprot:F8VYR5;uniprot:Q96EL2 +ACP2 GeneProduct ensembl:ENSG00000134575 "" ensembl:ENSG00000134575 ncbigene:53 hgnc.symbol:ACP2 uniprot:A0A5F9ZI20;uniprot:E9PQY3;uniprot:P11117;uniprot:E9PHY0;uniprot:A0A5F9ZHR7;uniprot:B7Z7D2;uniprot:A0A5F9ZH40;uniprot:B7Z6U3;uniprot:A0A5F9ZH82 +MPZL1 GeneProduct ensembl:ENSG00000197965 "" ensembl:ENSG00000197965 ncbigene:9019 hgnc.symbol:MPZL1 uniprot:F8WFC4;uniprot:A8K5D4;uniprot:A0A024R8Y3;uniprot:Q9UEL6;uniprot:O95297 +RTN4 GeneProduct ensembl:ENSG00000115310 "" ensembl:ENSG00000115310 ncbigene:57142 hgnc.symbol:RTN4 uniprot:C9J685;uniprot:A0A0U1RQR6;uniprot:H7C106;uniprot:Q9NQC3 +PODXL GeneProduct ensembl:ENSG00000128567 "" ensembl:ENSG00000128567 ncbigene:5420 hgnc.symbol:PODXL uniprot:O00592;uniprot:G3V0E6 +PPIB GeneProduct ensembl:ENSG00000166794 "" ensembl:ENSG00000166794 ncbigene:5479 hgnc.symbol:PPIB uniprot:P23284;uniprot:A0A7P0T7U3;uniprot:A0A7P0Z497;uniprot:A0A7P0TB45 +WNT5A GeneProduct ensembl:ENSG00000114251 "" ensembl:ENSG00000114251 ncbigene:7474 hgnc.symbol:WNT5A uniprot:A0A384N611;uniprot:P41221;uniprot:A0A024R316;uniprot:C9J8I8 +TRAM1 GeneProduct ensembl:ENSG00000067167 "" ensembl:ENSG00000067167 ncbigene:23471 hgnc.symbol:TRAM1 uniprot:Q15629;uniprot:G3XAN4;uniprot:Q6FHL3;uniprot:E5RFP8 +PKN2 GeneProduct ensembl:ENSG00000065243 "" ensembl:ENSG00000065243 ncbigene:5586 hgnc.symbol:PKN2 uniprot:H0Y429;uniprot:Q16513;uniprot:B1AL79;uniprot:H0Y5V5 +ADAR GeneProduct ensembl:ENSG00000160710 "" ensembl:ENSG00000160710 ncbigene:103 hgnc.symbol:ADAR uniprot:A0A3B3ISU1;uniprot:A0A7P0Z4F9;uniprot:A0A3B3ISX1;uniprot:A0A3B3IRQ9;uniprot:A0A7P0Z4K3;uniprot:A2IBT1;uniprot:A0A3B3ITG9;uniprot:A0A7P0TA14;uniprot:P55265 +MATR3 GeneProduct ensembl:ENSG00000015479 "" ensembl:ENSG00000015479 ncbigene:9782 hgnc.symbol:MATR3 uniprot:D6RBK5;uniprot:D6RBI2;uniprot:B3KM87;uniprot:D6REK4;uniprot:D6REM6;uniprot:P43243;uniprot:D6R991;uniprot:A0A1B0GX04;uniprot:D6RAY2;uniprot:D6RIA2;uniprot:D6RBS2;uniprot:H0Y8T4;uniprot:D6RE02;uniprot:D6R9F3 +USP1 GeneProduct ensembl:ENSG00000162607 "" ensembl:ENSG00000162607 ncbigene:7398 hgnc.symbol:USP1 uniprot:C9JC88;uniprot:C9JWX4;uniprot:O94782 +ITGA2 GeneProduct ensembl:ENSG00000164171 "" ensembl:ENSG00000164171 ncbigene:3673 hgnc.symbol:ITGA2 uniprot:D6RG08;uniprot:D6R9H3;uniprot:E7ESP4;uniprot:E7EMF1;uniprot:E9PB77;uniprot:P17301 +CCNG1 GeneProduct ensembl:ENSG00000113328 "" ensembl:ENSG00000113328 ncbigene:900 hgnc.symbol:CCNG1 uniprot:P51959;uniprot:D6RGX3;uniprot:D6RD30;uniprot:E7ERZ1;uniprot:D6RCC5 +LUZP1 GeneProduct ensembl:ENSG00000169641 "" ensembl:ENSG00000169641 ncbigene:7798 hgnc.symbol:LUZP1 uniprot:Q86V48;uniprot:E5RFK8;uniprot:E5RHU7 +CDIPT GeneProduct ensembl:ENSG00000103502 "" ensembl:ENSG00000103502 ncbigene:10423 hgnc.symbol:CDIPT uniprot:H3BTJ7;uniprot:H3BUR9;uniprot:O14735;uniprot:A8K3L7;uniprot:B3KY94 +AXL GeneProduct ensembl:ENSG00000167601 "" ensembl:ENSG00000167601 ncbigene:558 hgnc.symbol:AXL uniprot:M0R0W6;uniprot:P30530 +SCAMP1 GeneProduct ensembl:ENSG00000085365 "" ensembl:ENSG00000085365 ncbigene:9522 hgnc.symbol:SCAMP1 uniprot:A0A087WZA6;uniprot:A0A087WXB0;uniprot:A0A087WTX8;uniprot:O15126;uniprot:A0A087WU14 +ATRX GeneProduct ensembl:ENSG00000085224 "" ensembl:ENSG00000085224 ncbigene:546 hgnc.symbol:ATRX uniprot:A0A096LNW1;uniprot:P46100;uniprot:A0A096LPG6;uniprot:A0A096LNL9;uniprot:A0A6Q8PHA4;uniprot:H0Y3T0;uniprot:A0A096LNL6;uniprot:A0A096LNL7;uniprot:A0A096LNN3;uniprot:A0A096LNR8;uniprot:A0A096LP59;uniprot:A0A087WWG0;uniprot:A4LAA3;uniprot:A0A096LNX6 +SLC38A2 GeneProduct ensembl:ENSG00000134294 "" ensembl:ENSG00000134294 ncbigene:54407 hgnc.symbol:SLC38A2 uniprot:A0A024R0W3;uniprot:F8VUY8;uniprot:F8VQW8;uniprot:Q96QD8 +CA12 GeneProduct ensembl:ENSG00000074410 "" ensembl:ENSG00000074410 ncbigene:771 hgnc.symbol:CA12 uniprot:B3KUB4;uniprot:O43570 +CDK5RAP3 GeneProduct ensembl:ENSG00000108465 "" ensembl:ENSG00000108465 ncbigene:80279 hgnc.symbol:CDK5RAP3 uniprot:J3QL95;uniprot:J3KRI2;uniprot:J3KRK4;uniprot:J3KSD0;uniprot:J3QS62;uniprot:J3KTA5;uniprot:J3QQY1;uniprot:J3QL86;uniprot:J3QRX0;uniprot:J3QQS7;uniprot:J3QRM1;uniprot:J3KS63;uniprot:Q96JB5 +ARCN1 GeneProduct ensembl:ENSG00000095139 "" ensembl:ENSG00000095139 ncbigene:372 hgnc.symbol:ARCN1 uniprot:P48444;uniprot:E9PK34;uniprot:B0YIW5;uniprot:B0YIW6 +CSNK1D GeneProduct ensembl:ENSG00000141551 "" ensembl:ENSG00000141551 ncbigene:1453 hgnc.symbol:CSNK1D uniprot:J3KRM8;uniprot:P48730;uniprot:H7BYT1;uniprot:H0Y2N6;uniprot:J3QQU8;uniprot:J3QQI9;uniprot:J3KRS6;uniprot:B4DLF1;uniprot:J3QS70 +RARS GeneProduct ensembl:ENSG00000113643 "" ensembl:ENSG00000113643 ncbigene:5917 hgnc.symbol:RARS1 uniprot:E5RJM9;uniprot:E5RI24;uniprot:E5RH09;uniprot:P54136 +CGI-38 GeneProduct ensembl:ENSG00000159713 "" ensembl:ENSG00000159713 ncbigene:51673 hgnc.symbol:TPPP3 uniprot:Q9BW30;uniprot:A0A024R702 +SH3BP4 GeneProduct ensembl:ENSG00000130147 "" ensembl:ENSG00000130147 ncbigene:23677 hgnc.symbol:SH3BP4 uniprot:C9JED2;uniprot:Q9P0V3;uniprot:C9JF25;uniprot:C9JRG1;uniprot:C9JWW6 +RAB30 GeneProduct ensembl:ENSG00000137502 "" ensembl:ENSG00000137502 ncbigene:27314 hgnc.symbol:RAB30 uniprot:E9PNB9;uniprot:E9PRX0;uniprot:A8K5R1;uniprot:E9PI18;uniprot:E9PJQ5;uniprot:E9PMJ1;uniprot:Q15771;uniprot:E9PLM3;uniprot:E9PPW9;uniprot:E9PQ07;uniprot:H0YDK7;uniprot:E9PS06;uniprot:E9PRF7 +GNPNAT1 GeneProduct ensembl:ENSG00000100522 "" ensembl:ENSG00000100522 ncbigene:64841 hgnc.symbol:GNPNAT1 uniprot:A0A024R649;uniprot:G3V4W4;uniprot:G3V5E4;uniprot:Q96EK6 +RHEB GeneProduct ensembl:ENSG00000106615 "" ensembl:ENSG00000106615 ncbigene:6009 hgnc.symbol:RHEB uniprot:F8WBL3;uniprot:Q15382;uniprot:A0A090N900;uniprot:C9J469;uniprot:C9J931 +DHX40 GeneProduct ensembl:ENSG00000108406 "" ensembl:ENSG00000108406 ncbigene:79665 hgnc.symbol:DHX40 uniprot:J3KS08;uniprot:J3KSW6;uniprot:J3KSX9;uniprot:F5H625;uniprot:J3KTK0;uniprot:Q8IX18 +IFRD2 GeneProduct ensembl:ENSG00000186792 "" ensembl:ENSG00000186792 ncbigene:8372 hgnc.symbol:HYAL3 uniprot:O43820;uniprot:C9JB51 +ARF4 GeneProduct ensembl:ENSG00000168374 "" ensembl:ENSG00000168374 ncbigene:378 hgnc.symbol:ARF4 uniprot:P18085;uniprot:C9JAK5;uniprot:F8WDB3;uniprot:C9J6P1;uniprot:C9JPM4;uniprot:U3KQF2 +TMED7 GeneProduct ensembl:ENSG00000134970 "" ensembl:ENSG00000134970 ncbigene:51014 hgnc.symbol:TMED7 uniprot:G3V2Y2;uniprot:Q9Y3B3 +MIRLET7B GeneProduct ensembl:ENSG00000284520 "" ensembl:ENSG00000284520 ncbigene:406884 hgnc.symbol:MIRLET7B +MIRLET7C GeneProduct ensembl:ENSG00000199030 "" ensembl:ENSG00000199030 ncbigene:406885 hgnc.symbol:MIRLET7C +MIRLET7D GeneProduct ensembl:ENSG00000199133 "" ensembl:ENSG00000199133 ncbigene:406886 hgnc.symbol:MIRLET7D +MIRLET7E GeneProduct ensembl:ENSG00000198972 "" ensembl:ENSG00000198972 ncbigene:406887 hgnc.symbol:MIRLET7E +MIRLET7F1 GeneProduct ensembl:ENSG00000199072 "" ensembl:ENSG00000199072 ncbigene:406888 hgnc.symbol:MIRLET7F1 +MIRLET7F2 GeneProduct ensembl:ENSG00000208012 "" ensembl:ENSG00000208012 ncbigene:406889 hgnc.symbol:MIRLET7F2 +MIRLET7G GeneProduct ensembl:ENSG00000199150 "" ensembl:ENSG00000199150 ncbigene:406890 hgnc.symbol:MIRLET7G +MIR155 GeneProduct ensembl:ENSG00000283904 "" ensembl:ENSG00000283904 ncbigene:406947 hgnc.symbol:MIR155 +MIR17 GeneProduct ensembl:ENSG00000284536 "" ensembl:ENSG00000284536 ncbigene:406952 hgnc.symbol:MIR17 +MIR133A1 GeneProduct ensembl:ENSG00000283927 "" ensembl:ENSG00000283927 ncbigene:406922 hgnc.symbol:MIR133A1 +MIR133A2 GeneProduct ensembl:ENSG00000284508 "" ensembl:ENSG00000284508 ncbigene:406923 hgnc.symbol:MIR133A2 +MIR143 GeneProduct ensembl:ENSG00000284182 "" ensembl:ENSG00000284182 ncbigene:406935 hgnc.symbol:MIR143 +MIR20A GeneProduct hgnc.symbol:MIR20A "" ensembl:ENSG00000283762 ncbigene:406982 hgnc.symbol:MIR20A +MIR20A GeneProduct ensembl:ENSG00000283762 "" ensembl:ENSG00000283762 ncbigene:406982 hgnc.symbol:MIR20A +MIR223 GeneProduct ensembl:ENSG00000284567 "" ensembl:ENSG00000284567 ncbigene:407008 hgnc.symbol:MIR223 +MIR29B1 GeneProduct ensembl:ENSG00000283797 "" ensembl:ENSG00000283797 ncbigene:407024 hgnc.symbol:MIR29B1 +MIR29B2 GeneProduct ensembl:ENSG00000284203 "" ensembl:ENSG00000284203 ncbigene:407025 hgnc.symbol:MIR29B2 +MIR29A GeneProduct ensembl:ENSG00000284032 "" ensembl:ENSG00000284032 ncbigene:407021 hgnc.symbol:MIR29A +MIR29C GeneProduct ensembl:ENSG00000284214 "" ensembl:ENSG00000284214 ncbigene:407026 hgnc.symbol:MIR29C +MIR34A GeneProduct ensembl:ENSG00000284357 "" ensembl:ENSG00000284357 ncbigene:407040 hgnc.symbol:MIR34A +MIR34B GeneProduct ensembl:ENSG00000207811 "" ensembl:ENSG00000207811 ncbigene:407041 hgnc.symbol:MIR34B +MIR34C GeneProduct ensembl:ENSG00000207562 "" ensembl:ENSG00000207562 ncbigene:407042 hgnc.symbol:MIR34C +MIR92A2 GeneProduct ensembl:ENSG00000284538 "" ensembl:ENSG00000284538 ncbigene:407049 hgnc.symbol:MIR92A2 diff --git a/pathways/WP2005/WP2005.gpml b/pathways/WP2005/WP2005.gpml new file mode 100644 index 000000000..c96860e74 --- /dev/null +++ b/pathways/WP2005/WP2005.gpml @@ -0,0 +1,2620 @@ + + + This cataloge pathway was created using the database from "http://diana.cslab.ece.ntua.gr/tarbase/" with exclusions based on evidance type. This pathway only incldes miR targeted genes expressed in Muscle cells. This pathway is meant for data mapping. + e50 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + 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extends experimentally supported miRNA-gene interactions to cell-types and virally encoded miRNAs. Skoufos G, Kakoulidis P, Tastsoglou S, Zacharopoulou E, Kotsira V, Miliotis M, et al. Nucleic Acids Res. 2024 Jan 5;52(D1):D304–10. PubMed Europe PMC Scholia" diff --git a/pathways/WP2006/WP2006-datanodes.tsv b/pathways/WP2006/WP2006-datanodes.tsv new file mode 100644 index 000000000..dc4e8bab2 --- /dev/null +++ b/pathways/WP2006/WP2006-datanodes.tsv @@ -0,0 +1,132 @@ +Label Type Identifier Comment Ensembl NCBI gene HGNC UniProt Wikidata ChEBI InChI PubChem ChemSpider HMDB KEGG LipidMaps +GOLGA7 GeneProduct ensembl:ENSG00000147533 "" ensembl:ENSG00000147533 ncbigene:51125 hgnc.symbol:GOLGA7 uniprot:Q7Z5G4 +SFRS9 GeneProduct ensembl:ENSG00000111786 "" ensembl:ENSG00000111786 ncbigene:8683 hgnc.symbol:SRSF9 uniprot:S4R3G0;uniprot:H0YIB4;uniprot:Q13242 +MRPS33 GeneProduct ensembl:ENSG00000090263 "" ensembl:ENSG00000090263 ncbigene:51650 hgnc.symbol:MRPS33 uniprot:A4D1T3;uniprot:C9JBY7;uniprot:Q9Y291 +HMOX1 GeneProduct ensembl:ENSG00000100292 "" ensembl:ENSG00000100292 ncbigene:3162 hgnc.symbol:HMOX1 uniprot:A0A7I2V277;uniprot:Q6FH11;uniprot:A0A7I2V3M0;uniprot:A0A7I2YQL9;uniprot:P09601;uniprot:A0A7I2V3I1;uniprot:B1AHA8 +TMEM59 GeneProduct ensembl:ENSG00000116209 "" ensembl:ENSG00000116209 ncbigene:9528 hgnc.symbol:TMEM59 uniprot:Q9BXS4;uniprot:Q5T706;uniprot:Q5T703;uniprot:Q5T704;uniprot:Q5T6Z8 +HES1 GeneProduct ensembl:ENSG00000114315 "" ensembl:ENSG00000114315 ncbigene:3280 hgnc.symbol:HES1 uniprot:Q14469 +SMAD1 GeneProduct ensembl:ENSG00000170365 "" ensembl:ENSG00000170365 ncbigene:4086 hgnc.symbol:SMAD1 uniprot:D6RAY1;uniprot:D6RD62;uniprot:D6RDN7;uniprot:A0A1D5RMR4;uniprot:D6RBH9;uniprot:Q15797;uniprot:D6REQ3 +MET GeneProduct ensembl:ENSG00000105976 "" ensembl:ENSG00000105976 ncbigene:4233 hgnc.symbol:MET uniprot:A0A024R759;uniprot:P08581;uniprot:A0A024R728;uniprot:C9JKM5;uniprot:H7C130;uniprot:H7C174 +NP GeneProduct ensembl:ENSG00000198805 "" ensembl:ENSG00000198805 ncbigene:4860 hgnc.symbol:PNP uniprot:G3V2H3;uniprot:G3V393;uniprot:V9HWH6;uniprot:P00491;uniprot:G3V5M2 +TPM1 GeneProduct ensembl:ENSG00000140416 "" ensembl:ENSG00000140416 ncbigene:7168 hgnc.symbol:TPM1 uniprot:A0A494BZZ2;uniprot:A0A494C0V8;uniprot:A0A0K0K1I0;uniprot:A0A0S2Z4G6;uniprot:H0YKX5;uniprot:H7BYY1;uniprot:A0A494C0I0;uniprot:B7Z596;uniprot:F5H7S3;uniprot:H0YL80;uniprot:H0YK48;uniprot:H0YKP3;uniprot:P09493;uniprot:H0YLS7;uniprot:A0A087WTJ7;uniprot:H0YL42;uniprot:A0A024R5W6;uniprot:D9YZV4;uniprot:Q6ZN40;uniprot:D9YZV5;uniprot:H0YKJ4;uniprot:D9YZV7;uniprot:H0YN06 +GALNT7 GeneProduct ensembl:ENSG00000109586 "" ensembl:ENSG00000109586 ncbigene:51809 hgnc.symbol:GALNT7 uniprot:Q86SF2;uniprot:E9PBY3;uniprot:H0YAH3;uniprot:H0YAK0 +UBE2J1 GeneProduct ensembl:ENSG00000198833 "" ensembl:ENSG00000198833 ncbigene:51465 hgnc.symbol:UBE2J1 uniprot:Q9Y385 +ATP6V1C1 GeneProduct ensembl:ENSG00000155097 "" ensembl:ENSG00000155097 ncbigene:528 hgnc.symbol:ATP6V1C1 uniprot:P21283;uniprot:A0A024R9I0;uniprot:E7EV59 +COMMD9 GeneProduct ensembl:ENSG00000110442 "" ensembl:ENSG00000110442 ncbigene:29099 hgnc.symbol:COMMD9 uniprot:E9PJ95;uniprot:Q53FR9;uniprot:Q9P000 +RAB34 GeneProduct ensembl:ENSG00000109113 "" ensembl:ENSG00000109113 ncbigene:83871 hgnc.symbol:RAB34 uniprot:A0A024QZ68;uniprot:A0A1B0GTQ2;uniprot:V9GY61;uniprot:K7EIF2;uniprot:H7C0Y7;uniprot:E7ES60;uniprot:A0A1C7CYW6;uniprot:A0A1B0GWB1;uniprot:P0DI83;uniprot:C9JY26;uniprot:K7EJW7;uniprot:Q96PJ7;uniprot:A0A1B0GVI6;uniprot:Q9BZG1;uniprot:J3QLC6;uniprot:C9JBG0 +E2F3 GeneProduct ensembl:ENSG00000112242 "" ensembl:ENSG00000112242 ncbigene:1871 hgnc.symbol:E2F3 uniprot:O00716 +CBFB GeneProduct ensembl:ENSG00000067955 "" ensembl:ENSG00000067955 ncbigene:865 hgnc.symbol:CBFB uniprot:J3KRT0;uniprot:A0A024R6X2;uniprot:H3BSC0;uniprot:Q13951;uniprot:J3KS23;uniprot:A0A494C0A9;uniprot:J3KTD8 +TXNRD1 GeneProduct ensembl:ENSG00000198431 "" ensembl:ENSG00000198431 ncbigene:7296 hgnc.symbol:TXNRD1 uniprot:E9PKI4;uniprot:E9PLT3;uniprot:E9PQI3;uniprot:E9PKD3;uniprot:A0A0B4J225;uniprot:E9PIR7;uniprot:A0A182DWI3;uniprot:E9PIZ5;uniprot:Q16881;uniprot:E9PRI8 +PICALM GeneProduct ensembl:ENSG00000073921 "" ensembl:ENSG00000073921 ncbigene:8301 hgnc.symbol:PICALM uniprot:E9PJT1;uniprot:H0YCY1;uniprot:A0A024R5L7;uniprot:E9PI56;uniprot:E9PK13;uniprot:H0YD48;uniprot:H0YE97;uniprot:Q13492;uniprot:E9PKP6;uniprot:H0YEY8;uniprot:H0YEH1;uniprot:E9PLJ8;uniprot:H0YEF7;uniprot:A0A024R5P1 +TPM3 GeneProduct ensembl:ENSG00000143549 "" ensembl:ENSG00000143549 ncbigene:7170 hgnc.symbol:TPM3 uniprot:A0A494C0P6;uniprot:Q5VU61;uniprot:A0A494C034;uniprot:D6R904;uniprot:J3KN67;uniprot:D6RGJ6;uniprot:P06753;uniprot:A0A0S2Z4G4;uniprot:A0A2R2Y2Q3;uniprot:A0A087WWU8;uniprot:A0A0S2Z4I4;uniprot:A0A494C0G0 +MIR20A GeneProduct hgnc.symbol:MIR20A "" ensembl:ENSG00000283762 ncbigene:406982 hgnc.symbol:MIR20A +BET1 GeneProduct ensembl:ENSG00000105829 "" ensembl:ENSG00000105829 ncbigene:10282 hgnc.symbol:BET1 uniprot:O15155;uniprot:Q53XK0;uniprot:A0A3B3IU16;uniprot:H7C1N3;uniprot:Q68DU7;uniprot:C9JTT8 +TICAM2 GeneProduct ensembl:ENSG00000134970 "" ensembl:ENSG00000134970 ncbigene:51014 hgnc.symbol:TMED7 uniprot:G3V2Y2;uniprot:Q9Y3B3 +LAMC1 GeneProduct ensembl:ENSG00000135862 "" ensembl:ENSG00000135862 ncbigene:3915 hgnc.symbol:LAMC1 uniprot:P11047;uniprot:R4GNC7 +SLC4A10 GeneProduct ensembl:ENSG00000144290 "" ensembl:ENSG00000144290 ncbigene:57282 hgnc.symbol:SLC4A10 uniprot:E7EW28;uniprot:C9J240;uniprot:F8WDX9;uniprot:Q6U841 +HSD17B12 GeneProduct ensembl:ENSG00000149084 "" ensembl:ENSG00000149084 ncbigene:51144 hgnc.symbol:HSD17B12 uniprot:E9PI21;uniprot:A0A1B0GW85;uniprot:A0A1B0GVY6;uniprot:Q53GQ0;uniprot:A0A1B0GU83;uniprot:A0A1B0GV93;uniprot:A0A1B0GW27 +PWP1 GeneProduct ensembl:ENSG00000136045 "" ensembl:ENSG00000136045 ncbigene:11137 hgnc.symbol:PWP1 uniprot:A0A024RBH5;uniprot:F8VZ56;uniprot:Q13610;uniprot:B4DJV5 +POM121 GeneProduct ensembl:ENSG00000196313 "" ensembl:ENSG00000196313 ncbigene:9883 hgnc.symbol:POM121 uniprot:Q96HA1 +CUL4B GeneProduct ensembl:ENSG00000158290 "" ensembl:ENSG00000158290 ncbigene:8450 hgnc.symbol:CUL4B uniprot:A0A7P0Z4G9;uniprot:A0A7P0T9R8;uniprot:A0A7P0T9P5;uniprot:A0A669KAU9;uniprot:A0A7P0T954;uniprot:Q13620;uniprot:A0A7P0T9D0;uniprot:A0A669KAX4;uniprot:A0A7P0T809;uniprot:A0A804CL36;uniprot:K4DI93;uniprot:A0A7P0T8P8;uniprot:A0A7P0T9L3;uniprot:A0A7P0TAQ3;uniprot:A0A7P0Z4E4;uniprot:A0A7P0T9C8;uniprot:A0A7P0Z439;uniprot:A0A7P0T8W4;uniprot:A0A7P0TAF9;uniprot:A0A669KBG9;uniprot:A0A7P0T894 +DHX57 GeneProduct ensembl:ENSG00000163214 "" ensembl:ENSG00000163214 ncbigene:90957 hgnc.symbol:DHX57 uniprot:H7BZ23;uniprot:Q6P158;uniprot:H7C109;uniprot:A0A087WZ11;uniprot:A0A087WW12 +UBE2V1 GeneProduct ensembl:ENSG00000124208 "" ensembl:ENSG00000124208 ncbigene:387522 hgnc.symbol:PEDS1-UBE2V1 uniprot:I3L0A0 +FBXW1B GeneProduct ensembl:ENSG00000072803 "" ensembl:ENSG00000072803 ncbigene:23291 hgnc.symbol:FBXW11 uniprot:E5RGC1;uniprot:E5RG78;uniprot:Q9UKB1;uniprot:E5RH92 +SPCS3 GeneProduct ensembl:ENSG00000129128 "" ensembl:ENSG00000129128 ncbigene:60559 hgnc.symbol:SPCS3 uniprot:P61009 +NEDD4 GeneProduct ensembl:ENSG00000069869 "" ensembl:ENSG00000069869 ncbigene:4734 hgnc.symbol:NEDD4 uniprot:H0Y9L1;uniprot:H0Y8X6;uniprot:P46934;uniprot:A0A3B3IUC1;uniprot:H0YA37;uniprot:H0Y8H4 +THBS1 GeneProduct ensembl:ENSG00000137801 "" ensembl:ENSG00000137801 ncbigene:7057 hgnc.symbol:THBS1 uniprot:A8MZG1;uniprot:P07996 +KDELC2 GeneProduct ensembl:ENSG00000178202 "" ensembl:ENSG00000178202 ncbigene:143888 hgnc.symbol:POGLUT3 uniprot:Q7Z4H8;uniprot:H0YEM3;uniprot:A0A024R3C4 +GNAI2 GeneProduct ensembl:ENSG00000114353 "" ensembl:ENSG00000114353 ncbigene:2771 hgnc.symbol:GNAI2 uniprot:P04899;uniprot:F8WE78;uniprot:F8WBG4 +MAP3K8 GeneProduct ensembl:ENSG00000107968 "" ensembl:ENSG00000107968 ncbigene:1326 hgnc.symbol:MAP3K8 uniprot:Q5T857;uniprot:Q5T853;uniprot:Q5T854;uniprot:P41279 +NCL GeneProduct ensembl:ENSG00000115053 "" ensembl:ENSG00000115053 ncbigene:4691 hgnc.symbol:NCL uniprot:A0A7I2V2U7;uniprot:A0A7I2V699;uniprot:A0A7I2V349;uniprot:A0A7I2V2S8;uniprot:A0A7I2V428;uniprot:A0A7I2V506;uniprot:C9JLB1;uniprot:H7BY16;uniprot:P19338;uniprot:A0A7I2V5M5;uniprot:A0A7I2V3F3 +ARF4 GeneProduct ensembl:ENSG00000168374 "" ensembl:ENSG00000168374 ncbigene:378 hgnc.symbol:ARF4 uniprot:P18085;uniprot:C9JAK5;uniprot:F8WDB3;uniprot:C9J6P1;uniprot:C9JPM4;uniprot:U3KQF2 +CTDSP1 GeneProduct ensembl:ENSG00000144579 "" ensembl:ENSG00000144579 ncbigene:58190 hgnc.symbol:CTDSP1 uniprot:H7C270;uniprot:Q9GZU7;uniprot:H7C1Z7;uniprot:H7C3E0 +HNRPM GeneProduct ensembl:ENSG00000099783 "" ensembl:ENSG00000099783 ncbigene:4670 hgnc.symbol:HNRNPM uniprot:M0QYQ7;uniprot:M0R2I7;uniprot:M0QYL3;uniprot:M0QY96;uniprot:P52272;uniprot:M0R0N3;uniprot:M0R019;uniprot:M0R2T0;uniprot:A0A087X0X3;uniprot:M0QZM1;uniprot:M0R0Y6 +SLC38A1 GeneProduct ensembl:ENSG00000111371 "" ensembl:ENSG00000111371 ncbigene:81539 hgnc.symbol:SLC38A1 uniprot:Q9H2H9;uniprot:F8VX04;uniprot:F8VX12;uniprot:A0A024R124 +ATRX GeneProduct ensembl:ENSG00000085224 "" ensembl:ENSG00000085224 ncbigene:546 hgnc.symbol:ATRX uniprot:A0A096LNW1;uniprot:P46100;uniprot:A0A096LPG6;uniprot:A0A096LNL9;uniprot:A0A6Q8PHA4;uniprot:H0Y3T0;uniprot:A0A096LNL6;uniprot:A0A096LNL7;uniprot:A0A096LNN3;uniprot:A0A096LNR8;uniprot:A0A096LP59;uniprot:A0A087WWG0;uniprot:A4LAA3;uniprot:A0A096LNX6 +ARFIP1 GeneProduct ensembl:ENSG00000164144 "" ensembl:ENSG00000164144 ncbigene:27236 hgnc.symbol:ARFIP1 uniprot:B4E273;uniprot:P53367 +TMED2 GeneProduct ensembl:ENSG00000086598 "" ensembl:ENSG00000086598 ncbigene:10959 hgnc.symbol:TMED2 uniprot:E7EQ72;uniprot:F5GX39;uniprot:Q15363;uniprot:Q6FHT8 +ATP2A2 GeneProduct ensembl:ENSG00000174437 "" ensembl:ENSG00000174437 ncbigene:488 hgnc.symbol:ATP2A2 uniprot:A0A0C4DH86;uniprot:A0A0S2Z3L2;uniprot:H7C5W9;uniprot:P16615;uniprot:J3QSY6;uniprot:F8W1Z7 +POLR2C GeneProduct ensembl:ENSG00000102978 "" ensembl:ENSG00000102978 ncbigene:5432 hgnc.symbol:POLR2C uniprot:H3BRR2;uniprot:P19387;uniprot:Q6FGR6 +ANXA2 GeneProduct ensembl:ENSG00000182718 "" ensembl:ENSG00000182718 ncbigene:302 hgnc.symbol:ANXA2 uniprot:H0YNA0;uniprot:H0YKZ7;uniprot:H0YM50;uniprot:H0YMD9;uniprot:H0YNB8;uniprot:P07355;uniprot:H0YKN4;uniprot:H0YMM1;uniprot:H0YMU9;uniprot:H0YMW4;uniprot:A0A7I2V4P4;uniprot:H0YKV8;uniprot:A0A024R5Z7;uniprot:H0YKS4;uniprot:H0YKX9;uniprot:H0YL33;uniprot:H0YLV6;uniprot:H0YN42;uniprot:H0YLE2;uniprot:H0YMD0;uniprot:H0YKL9;uniprot:H0YNP5;uniprot:H0YMT9;uniprot:H0YN28 +SDCBP GeneProduct ensembl:ENSG00000137575 "" ensembl:ENSG00000137575 ncbigene:6386 hgnc.symbol:SDCBP uniprot:B4DHN5;uniprot:O00560;uniprot:G5EA09;uniprot:A0A024R7Z5;uniprot:E9PBU7 +FNDC3A GeneProduct ensembl:ENSG00000102531 "" ensembl:ENSG00000102531 ncbigene:22862 hgnc.symbol:FNDC3A uniprot:H7C507;uniprot:A0A024RDV5;uniprot:Q9Y2H6;uniprot:G5E9X3;uniprot:A0A087X1M6;uniprot:A0A024RDT9 +THBS1 GeneProduct ensembl:ENSG00000137801 "" ensembl:ENSG00000137801 ncbigene:7057 hgnc.symbol:THBS1 uniprot:A8MZG1;uniprot:P07996 +DNAJB1 GeneProduct ensembl:ENSG00000132002 "" ensembl:ENSG00000132002 ncbigene:3337 hgnc.symbol:DNAJB1 uniprot:M0R1D6;uniprot:Q6FHS4;uniprot:A0A7I2YQW1;uniprot:M0QZD0;uniprot:M0R128;uniprot:A0A1B0GX60;uniprot:M0R080;uniprot:M0QYT3;uniprot:M0QXK0;uniprot:A0A7I2V3K7;uniprot:P25685 +VCAM1 GeneProduct ensembl:ENSG00000162692 "" ensembl:ENSG00000162692 ncbigene:7412 hgnc.symbol:VCAM1 uniprot:A0A3B3ISS8;uniprot:P19320;uniprot:E9PDD2 +NRP1 GeneProduct ensembl:ENSG00000099250 "" ensembl:ENSG00000099250 ncbigene:8829 hgnc.symbol:NRP1 uniprot:H0Y7Z2;uniprot:E9PEP6;uniprot:E7EX60;uniprot:H0Y4N6;uniprot:V9GYL7;uniprot:Q5JWQ2;uniprot:Q5JWQ4;uniprot:H0Y4A0;uniprot:Q5JWQ6;uniprot:Q5T7F0;uniprot:O14786 +PPP1R7 GeneProduct ensembl:ENSG00000115685 "" ensembl:ENSG00000115685 ncbigene:5510 hgnc.symbol:PPP1R7 uniprot:C9J177;uniprot:C9JRC4;uniprot:B5MBZ8;uniprot:H7C3Q5;uniprot:H7C118;uniprot:C9JD73;uniprot:Q15435;uniprot:A0A140VK83;uniprot:H7C003 +IDH1 GeneProduct ensembl:ENSG00000138413 "" ensembl:ENSG00000138413 ncbigene:3417 hgnc.symbol:IDH1 uniprot:A0A024R3Y6;uniprot:C9JLU6;uniprot:O75874;uniprot:C9JJE5;uniprot:C9J4N6 +ADIPOR2 GeneProduct ensembl:ENSG00000006831 "" ensembl:ENSG00000006831 ncbigene:79602 hgnc.symbol:ADIPOR2 uniprot:Q86V24 +HMGA1 GeneProduct ensembl:ENSG00000137309 "" ensembl:ENSG00000137309 ncbigene:3159 hgnc.symbol:HMGA1 uniprot:A0A669KAX1;uniprot:P17096;uniprot:Q5T6U8 +FNDC3B GeneProduct ensembl:ENSG00000075420 "" ensembl:ENSG00000075420 ncbigene:64778 hgnc.symbol:FNDC3B uniprot:C9JKH7;uniprot:Q53EP0 +TMED7 GeneProduct ensembl:ENSG00000134970 "" ensembl:ENSG00000134970 ncbigene:51014 hgnc.symbol:TMED7 uniprot:G3V2Y2;uniprot:Q9Y3B3 +SRPRB GeneProduct ensembl:ENSG00000144867 "" ensembl:ENSG00000144867 ncbigene:58477 hgnc.symbol:SRPRB uniprot:Q549N5;uniprot:C9J5Z8;uniprot:Q9Y5M8;uniprot:H7C4H2 +FGF2 GeneProduct ensembl:ENSG00000138685 "" ensembl:ENSG00000138685 ncbigene:2247 hgnc.symbol:FGF2 uniprot:A0A0A0MQV6;uniprot:D9ZGF5;uniprot:P09038 +PODXL GeneProduct ensembl:ENSG00000128567 "" ensembl:ENSG00000128567 ncbigene:5420 hgnc.symbol:PODXL uniprot:O00592;uniprot:G3V0E6 +AXL GeneProduct ensembl:ENSG00000167601 "" ensembl:ENSG00000167601 ncbigene:558 hgnc.symbol:AXL uniprot:M0R0W6;uniprot:P30530 +ANPEP GeneProduct ensembl:ENSG00000166825 "" ensembl:ENSG00000166825 ncbigene:290 hgnc.symbol:ANPEP uniprot:H0YM04;uniprot:A0A024RC61;uniprot:H0YMC1;uniprot:H0YLZ8;uniprot:H0YKT6;uniprot:P15144 +PDLIM7 GeneProduct ensembl:ENSG00000196923 "" ensembl:ENSG00000196923 ncbigene:9260 hgnc.symbol:PDLIM7 uniprot:D6RH06;uniprot:D6RAN1;uniprot:H7BYK4;uniprot:D6RF83;uniprot:Q9NR12 +MTPN GeneProduct ensembl:ENSG00000105887 "" ensembl:ENSG00000105887 ncbigene:136319 hgnc.symbol:MTPN uniprot:Q69YG1;uniprot:P58546;uniprot:C9JL85 +GYS1 GeneProduct ensembl:ENSG00000104812 "" ensembl:ENSG00000104812 ncbigene:2997 hgnc.symbol:GYS1 uniprot:M0QYU1;uniprot:P13807 +ELOVL5 GeneProduct ensembl:ENSG00000012660 "" ensembl:ENSG00000012660 ncbigene:60481 hgnc.symbol:ELOVL5 uniprot:A0A0A0MTI6;uniprot:Q9NYP7;uniprot:A0A024RD35 +PKM2 GeneProduct ensembl:ENSG00000067225 "" ensembl:ENSG00000067225 ncbigene:5315 hgnc.symbol:PKM uniprot:P14618;uniprot:H3BN34;uniprot:H3BUW1;uniprot:B4DNK4;uniprot:H3BQZ3;uniprot:A0A804F6T5;uniprot:H3BT25;uniprot:H3BU13;uniprot:H3BQ34;uniprot:A0A024R5Z9;uniprot:H3BTJ2;uniprot:A0A804F729;uniprot:H3BTN5;uniprot:V9HWB8 +SEC23A GeneProduct ensembl:ENSG00000100934 "" ensembl:ENSG00000100934 ncbigene:10484 hgnc.symbol:SEC23A uniprot:G3V5K1;uniprot:G3V1W4;uniprot:G3V4V1;uniprot:G3V3G5;uniprot:Q15436;uniprot:F5H365;uniprot:G3V2R6;uniprot:G3V4Q2;uniprot:G3V5X8 +PDCD4 GeneProduct ensembl:ENSG00000150593 "" ensembl:ENSG00000150593 ncbigene:27250 hgnc.symbol:PDCD4 uniprot:Q53EL6;uniprot:Q5VZS7 +MOV10 GeneProduct ensembl:ENSG00000155363 "" ensembl:ENSG00000155363 ncbigene:4343 hgnc.symbol:MOV10 uniprot:Q5JR04;uniprot:Q9HCE1 +PISD GeneProduct ensembl:ENSG00000241878 "" ensembl:ENSG00000241878 ncbigene:23761 hgnc.symbol:PISD uniprot:A0A024R1K5;uniprot:B1AKM9;uniprot:H0Y7P7;uniprot:F8WCS6;uniprot:B1AKM6;uniprot:B1AKM8;uniprot:Q9UG56;uniprot:B1AKN0 +ANP32B GeneProduct ensembl:ENSG00000136938 "" ensembl:ENSG00000136938 ncbigene:10541 hgnc.symbol:ANP32B uniprot:Q92688 +CPNE8 GeneProduct ensembl:ENSG00000139117 "" ensembl:ENSG00000139117 ncbigene:144402 hgnc.symbol:CPNE8 uniprot:E7ENV7;uniprot:Q86YQ8;uniprot:F8VZB5 +P4HA2 GeneProduct ensembl:ENSG00000072682 "" ensembl:ENSG00000072682 ncbigene:8974 hgnc.symbol:P4HA2 uniprot:C9JCP0;uniprot:E7EPI9;uniprot:C9JFJ1;uniprot:C9JN43;uniprot:O15460;uniprot:C9JX45;uniprot:E7ENX0;uniprot:A8MXE0;uniprot:C9JIG4;uniprot:E7ERI1 +ADAR GeneProduct ensembl:ENSG00000160710 "" ensembl:ENSG00000160710 ncbigene:103 hgnc.symbol:ADAR uniprot:A0A3B3ISU1;uniprot:A0A7P0Z4F9;uniprot:A0A3B3ISX1;uniprot:A0A3B3IRQ9;uniprot:A0A7P0Z4K3;uniprot:A2IBT1;uniprot:A0A3B3ITG9;uniprot:A0A7P0TA14;uniprot:P55265 +MAGT1 GeneProduct ensembl:ENSG00000102158 "" ensembl:ENSG00000102158 ncbigene:84061 hgnc.symbol:MAGT1 uniprot:A0A087WU53;uniprot:Q9H0U3 +NF2 GeneProduct ensembl:ENSG00000186575 "" ensembl:ENSG00000186575 ncbigene:4771 hgnc.symbol:NF2 uniprot:A0A5F9ZHA0;uniprot:A0A5K1VW66;uniprot:A0A024R1J8;uniprot:A0A024R1J9;uniprot:A0A5F9ZHD8;uniprot:P35240;uniprot:A0A024R1F6;uniprot:A0A024R1D9;uniprot:A0A024R1I0 +TBCA GeneProduct ensembl:ENSG00000171530 "" ensembl:ENSG00000171530 ncbigene:6902 hgnc.symbol:TBCA uniprot:E5RIW3;uniprot:E5RIX8;uniprot:A0A494C144;uniprot:E5RHG6;uniprot:E5RJD8;uniprot:E5RJM1;uniprot:O75347;uniprot:Q6FGD7 +HBXIP GeneProduct ensembl:ENSG00000134248 "" ensembl:ENSG00000134248 ncbigene:10542 hgnc.symbol:LAMTOR5 uniprot:E9PLX3;uniprot:R4GMU8;uniprot:A0A0C4DGV4;uniprot:O43504 +ATP6V1F GeneProduct ensembl:ENSG00000128524 "" ensembl:ENSG00000128524 ncbigene:9296 hgnc.symbol:ATP6V1F uniprot:Q16864;uniprot:A4D1K0 +SLC38A2 GeneProduct ensembl:ENSG00000134294 "" ensembl:ENSG00000134294 ncbigene:54407 hgnc.symbol:SLC38A2 uniprot:A0A024R0W3;uniprot:F8VUY8;uniprot:F8VQW8;uniprot:Q96QD8 +GALNT1 GeneProduct ensembl:ENSG00000141429 "" ensembl:ENSG00000141429 ncbigene:2589 hgnc.symbol:GALNT1 uniprot:K7EK46;uniprot:K7EJV8;uniprot:Q10472;uniprot:A0A024RC48 +TRAM1 GeneProduct ensembl:ENSG00000067167 "" ensembl:ENSG00000067167 ncbigene:23471 hgnc.symbol:TRAM1 uniprot:Q15629;uniprot:G3XAN4;uniprot:Q6FHL3;uniprot:E5RFP8 +PRPF40A GeneProduct ensembl:ENSG00000196504 "" ensembl:ENSG00000196504 ncbigene:55660 hgnc.symbol:PRPF40A uniprot:H7C2N3;uniprot:H0YG38;uniprot:H7BXZ7;uniprot:O75400;uniprot:A0A7N4I394;uniprot:F5H578 +TNFRSF10B GeneProduct ensembl:ENSG00000120889 "" ensembl:ENSG00000120889 ncbigene:8795 hgnc.symbol:TNFRSF10B uniprot:E9PBT3;uniprot:O14763 +GFPT1 GeneProduct ensembl:ENSG00000198380 "" ensembl:ENSG00000198380 ncbigene:2673 hgnc.symbol:GFPT1 uniprot:Q06210;uniprot:A0A6I8PRT6;uniprot:A0A6I8PTT9;uniprot:A0A6I8PRN4 +TGFBR2 GeneProduct ensembl:ENSG00000163513 "" ensembl:ENSG00000163513 ncbigene:7048 hgnc.symbol:TGFBR2 uniprot:D2JYI1;uniprot:P37173;uniprot:A3QNQ0 +ATP6V0E GeneProduct ensembl:ENSG00000113732 "" ensembl:ENSG00000113732 ncbigene:8992 hgnc.symbol:ATP6V0E1 uniprot:O15342;uniprot:J3KN48;uniprot:E5RHL5 +DHX40 GeneProduct ensembl:ENSG00000108406 "" ensembl:ENSG00000108406 ncbigene:79665 hgnc.symbol:DHX40 uniprot:J3KS08;uniprot:J3KSW6;uniprot:J3KSX9;uniprot:F5H625;uniprot:J3KTK0;uniprot:Q8IX18 +OPRS1 GeneProduct ensembl:ENSG00000147955 "" ensembl:ENSG00000147955 ncbigene:10280 hgnc.symbol:SIGMAR1 uniprot:B4DR71;uniprot:A0A7P0T9D5;uniprot:Q5T1J1;uniprot:Q99720;uniprot:A0A7P0TA12;uniprot:A0A7P0Z4C2;uniprot:A2A3U5 +VEZT / vezatin GeneProduct ensembl:ENSG00000028203 "" ensembl:ENSG00000028203 ncbigene:55591 hgnc.symbol:VEZT uniprot:F8VXA0;uniprot:F8VVS3;uniprot:F8W8C2;uniprot:F8VRY3;uniprot:F8W0S0;uniprot:Q9HBM0;uniprot:F8VPN9;uniprot:F8VUB7;uniprot:F8W088;uniprot:F8VUG0;uniprot:F8W048;uniprot:F8VS43 +ACAA2 GeneProduct ensembl:ENSG00000167315 "" ensembl:ENSG00000167315 ncbigene:10449 hgnc.symbol:ACAA2 uniprot:K7EJ68;uniprot:A0A0B4J2A4;uniprot:K7EME0;uniprot:K7EJB1;uniprot:P42765;uniprot:K7ER88 +RTN4 GeneProduct ensembl:ENSG00000115310 "" ensembl:ENSG00000115310 ncbigene:57142 hgnc.symbol:RTN4 uniprot:C9J685;uniprot:A0A0U1RQR6;uniprot:H7C106;uniprot:Q9NQC3 +MRPL20 GeneProduct ensembl:ENSG00000242485 "" ensembl:ENSG00000242485 ncbigene:55052 hgnc.symbol:MRPL20 uniprot:Q9BYC9;uniprot:I3L2X1 +SH3BGRL3 GeneProduct ensembl:ENSG00000142669 "" ensembl:ENSG00000142669 ncbigene:83442 hgnc.symbol:SH3BGRL3 uniprot:Q9H299;uniprot:Q5T123 +FAM96A GeneProduct ensembl:ENSG00000166797 "" ensembl:ENSG00000166797 ncbigene:84191 hgnc.symbol:CIAO2A uniprot:H0YLH6;uniprot:H0YKV4;uniprot:Q9H5X1 +tuba3 GeneProduct ensembl:ENSG00000167552 "" ensembl:ENSG00000167552 ncbigene:7846 hgnc.symbol:TUBA1A uniprot:F8VRZ4;uniprot:Q71U36;uniprot:F8W0F6;uniprot:F8VQQ4;uniprot:A0A7P0Z4A1 +SPTLC1 GeneProduct ensembl:ENSG00000090054 "" ensembl:ENSG00000090054 ncbigene:10558 hgnc.symbol:SPTLC1 uniprot:A0A2R8Y4S0;uniprot:A0A024R277;uniprot:A0A2R8Y6A2;uniprot:A0A2R8Y763;uniprot:O15269 +AP2A1 GeneProduct ensembl:ENSG00000196961 "" ensembl:ENSG00000196961 ncbigene:160 hgnc.symbol:AP2A1 uniprot:M0R2D9;uniprot:O95782 +TMEM43 GeneProduct ensembl:ENSG00000170876 "" ensembl:ENSG00000170876 ncbigene:79188 hgnc.symbol:TMEM43 uniprot:F8WDL3;uniprot:Q9BTV4;uniprot:A0A024R2F9 +MRC2 GeneProduct ensembl:ENSG00000011028 "" ensembl:ENSG00000011028 ncbigene:9902 hgnc.symbol:MRC2 uniprot:J3KRF1;uniprot:J3QQZ6;uniprot:Q9UBG0;uniprot:E7EME3 +AP3D1 GeneProduct ensembl:ENSG00000065000 "" ensembl:ENSG00000065000 ncbigene:8943 hgnc.symbol:AP3D1 uniprot:A0A2R8Y4J3;uniprot:A0A087WYN6;uniprot:K7ELX8;uniprot:A0A2R8YCY8;uniprot:O14617;uniprot:K7ERW8 +NRAS GeneProduct ensembl:ENSG00000009307 "" ensembl:ENSG00000009307 ncbigene:7812 hgnc.symbol:CSDE1 uniprot:E9PLT0;uniprot:A0A024R0E2;uniprot:E9PJK7;uniprot:A0A1Y8EMC9;uniprot:E9PLD4;uniprot:E9PNG3;uniprot:O75534;uniprot:A0A024R0K2;uniprot:E9PKN4 +PXDN GeneProduct ensembl:ENSG00000130508 "" ensembl:ENSG00000130508 ncbigene:7837 hgnc.symbol:PXDN uniprot:H7C1W1;uniprot:C9J4I9;uniprot:H7C300;uniprot:Q92626;uniprot:H7C3W2 +CHMP2A GeneProduct ensembl:ENSG00000130724 "" ensembl:ENSG00000130724 ncbigene:27243 hgnc.symbol:CHMP2A uniprot:M0R1T5;uniprot:O43633;uniprot:A0A024R4S0;uniprot:M0QXX8;uniprot:M0R1L7 +FMNL2 GeneProduct ensembl:ENSG00000157827 "" ensembl:ENSG00000157827 ncbigene:114793 hgnc.symbol:FMNL2 uniprot:Q96PY5;uniprot:C9IZY8 +POLD2 GeneProduct ensembl:ENSG00000106628 "" ensembl:ENSG00000106628 ncbigene:5425 hgnc.symbol:POLD2 uniprot:F8W8R3;uniprot:P49005;uniprot:C9IZD2;uniprot:C9JHC7;uniprot:H7C1B3;uniprot:A0A087WWF6;uniprot:C9JLE1 +PTMA GeneProduct ensembl:ENSG00000187514 "" ensembl:ENSG00000187514 ncbigene:5757 hgnc.symbol:PTMA uniprot:F8WCE8;uniprot:H7C2N1;uniprot:B8ZZA1;uniprot:B8ZZW7;uniprot:B8ZZQ6;uniprot:P06454;uniprot:Q53S24;uniprot:H7C031 +ARCN1 GeneProduct ensembl:ENSG00000095139 "" ensembl:ENSG00000095139 ncbigene:372 hgnc.symbol:ARCN1 uniprot:P48444;uniprot:E9PK34;uniprot:B0YIW5;uniprot:B0YIW6 +AKAP8 GeneProduct ensembl:ENSG00000105127 "" ensembl:ENSG00000105127 ncbigene:10270 hgnc.symbol:AKAP8 uniprot:M0QX51;uniprot:A0A7P0TBC8;uniprot:A0A7P0TAA4;uniprot:O43823;uniprot:A0A7P0T893 +MPZL1 GeneProduct ensembl:ENSG00000197965 "" ensembl:ENSG00000197965 ncbigene:9019 hgnc.symbol:MPZL1 uniprot:F8WFC4;uniprot:A8K5D4;uniprot:A0A024R8Y3;uniprot:Q9UEL6;uniprot:O95297 +GAS2L1 GeneProduct ensembl:ENSG00000185340 "" ensembl:ENSG00000185340 ncbigene:10634 hgnc.symbol:GAS2L1 uniprot:A0A5E8;uniprot:C9JFI0;uniprot:A0A384P5D0;uniprot:C9JRR6;uniprot:Q99501 +SH3BP4 GeneProduct ensembl:ENSG00000130147 "" ensembl:ENSG00000130147 ncbigene:23677 hgnc.symbol:SH3BP4 uniprot:C9JED2;uniprot:Q9P0V3;uniprot:C9JF25;uniprot:C9JRG1;uniprot:C9JWW6 +SYNE2 GeneProduct ensembl:ENSG00000054654 "" ensembl:ENSG00000054654 ncbigene:23224 hgnc.symbol:SYNE2 uniprot:A0A669KBH2;uniprot:G3V2Q0;uniprot:G3V5X4;uniprot:A0A669KB22;uniprot:G3V3D4;uniprot:A0A669KB61;uniprot:A0A0C4DGK3;uniprot:A0A1W2PRN9;uniprot:A0A1W2PS37;uniprot:Q8WXH0;uniprot:G3V4T3;uniprot:A0A669KBG2;uniprot:G3V5N1 +YWHAQ GeneProduct ensembl:ENSG00000134308 "" ensembl:ENSG00000134308 ncbigene:10971 hgnc.symbol:YWHAQ uniprot:P27348;uniprot:E9PG15 +SLC12A2 GeneProduct ensembl:ENSG00000064651 "" ensembl:ENSG00000064651 ncbigene:6558 hgnc.symbol:SLC12A2 uniprot:G3XAL9;uniprot:P55011;uniprot:Q53ZR1 +HOXA7 GeneProduct ensembl:ENSG00000122592 "" ensembl:ENSG00000122592 ncbigene:3204 hgnc.symbol:HOXA7 uniprot:E5RHM9;uniprot:P31268 +RAI14 GeneProduct ensembl:ENSG00000039560 "" ensembl:ENSG00000039560 ncbigene:26064 hgnc.symbol:RAI14 uniprot:Q9P0K7;uniprot:D6RE17;uniprot:D6REL2;uniprot:D6RDL2;uniprot:D6RBY4;uniprot:D6RF74;uniprot:D6RBW6;uniprot:D6R9G6;uniprot:D6RB27;uniprot:D6R9G4;uniprot:D6RB25 +RHEB GeneProduct ensembl:ENSG00000106615 "" ensembl:ENSG00000106615 ncbigene:6009 hgnc.symbol:RHEB uniprot:F8WBL3;uniprot:Q15382;uniprot:A0A090N900;uniprot:C9J469;uniprot:C9J931 +TMED10 GeneProduct ensembl:ENSG00000170348 "" ensembl:ENSG00000170348 ncbigene:10972 hgnc.symbol:TMED10 uniprot:G3V2K7;uniprot:A0A024R6I3;uniprot:P49755 +RARS GeneProduct ensembl:ENSG00000113643 "" ensembl:ENSG00000113643 ncbigene:5917 hgnc.symbol:RARS1 uniprot:E5RJM9;uniprot:E5RI24;uniprot:E5RH09;uniprot:P54136 +MIRLET7B GeneProduct ensembl:ENSG00000284520 "" ensembl:ENSG00000284520 ncbigene:406884 hgnc.symbol:MIRLET7B +MIR155 GeneProduct ensembl:ENSG00000283904 "" ensembl:ENSG00000283904 ncbigene:406947 hgnc.symbol:MIR155 +MIR29C GeneProduct hgnc.symbol:MIR29C "" ensembl:ENSG00000284214 ncbigene:407026 hgnc.symbol:MIR29C +MIR34A GeneProduct ensembl:ENSG00000284357 "" ensembl:ENSG00000284357 ncbigene:407040 hgnc.symbol:MIR34A +MIR133A1 GeneProduct ensembl:ENSG00000283927 "" ensembl:ENSG00000283927 ncbigene:406922 hgnc.symbol:MIR133A1 +MIR133A2 GeneProduct ensembl:ENSG00000284508 "" ensembl:ENSG00000284508 ncbigene:406923 hgnc.symbol:MIR133A2 diff --git a/pathways/WP2006/WP2006.gpml b/pathways/WP2006/WP2006.gpml new file mode 100644 index 000000000..92a93f89e --- /dev/null +++ b/pathways/WP2006/WP2006.gpml @@ -0,0 +1,988 @@ + + + This catalogue pathway was created using the database from "http://diana.cslab.ece.ntua.gr/tarbase/" with exclusions based on evidance type. This pathway only incldes miR targeted genes expressed in Muscle cells. This pathway is meant for data mapping. + d4b + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + 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supported miRNA-gene interactions to cell-types and virally encoded miRNAs. + Nucleic Acids Res + 2024 + Skoufos G + Kakoulidis P + Tastsoglou S + Zacharopoulou E + Kotsira V + Miliotis M + Mavromati G + Grigoriadis D + Zioga M + Velli A + Koutou I + Karagkouni D + Stavropoulos S + Kardaras FS + Lifousi A + Vavalou E + Ovsepian A + Skoulakis A + Tasoulis SK + Georgakopoulos SV + Plagianakos VP + Hatzigeorgiou AG + + + miRNA pathway + PW:0000808 + Pathway Ontology + + + + diff --git a/pathways/WP2006/WP2006.json b/pathways/WP2006/WP2006.json new file mode 100644 index 000000000..0716fda2d --- /dev/null +++ b/pathways/WP2006/WP2006.json @@ -0,0 +1,10881 @@ +{ + "entitiesById": { + "a0ebc": { + "drawAs": "rect", + "fill": "#ffffff", + "fontFamily": "Arial", + "fontSize": 10, + "fontStyle": "normal", + "fontWeight": "normal", + "gpmlElementName": "DataNode", + "height": 20, + "id": "a0ebc", + "isPartOf": "d6187", + "kaavioType": "SingleFreeNode", + "lineHeight": 1.1, + "overflow": 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+ + + CBFB + + + + + + HSD17B12 + + + + + + CUL4B + + + + + + ARFIP1 + + + + + + PICALM + + + + + + SDCBP + + + + + + PODXL + + + + + + TBCA + + + + + + DNAJB1 + + + + + + TRAM1 + + + + + + DHX40 + + + + + + SMAD1 + + + + + + FMNL2 + + + + + + MPZL1 + + + + + + SH3BP4 + + + + + + SYNE2 + + + + + + RAI14 + + + + + + RHEB + + + + + + + + + TPM1 + + + + + + PDCD4 + + + + + + + MIRLET7B + + + + + + + + MIRLET7A1 + + + + + + MIRLET7A2 + + + + + + MIRLET7A3 + + + + + + + MIR155 + + + + + + + + MIR16-1 + + + + + + MIR16-2 + + + + + + + + + MIR1-1 + + + + + + MIR1-2 + + + + + + + + + MIR30A + + + + + + MIR30B + + + + + + MIR30C1 + + + + + + MIR30A + + + + + + MIR30C2 + + + + + + MIR30D + + + + + + MIR30E + + + + + + + MIR103A1 + + + + + + + + MIR124-1 + + + + + + MIR124-2 + + + + + + MIR124-3 + + + + + + + MIR21 + + + + + + + + MIR23A + + + + + + MIR23B + + + + + + + + + MIR26A1 + + + + + + MIR26A2 + + + + + + + MIR29C + + + + + + MIR30A + + + + + + MIR34A + + + + + + + + MIR199A1 + + + + + + MIR199A2 + + + + + + + + + MIR196A1 + + + + + + MIR196A2 + + + + + + MIR196B + + + + + + + MIR133B + + + + + + + + MIR133A1 + + + + + + MIR133A2 + + + + + + + + + MIR124-1 + + + + + + MIR124-2 + + + + + + MIR124-3 + + + + + Name: miR-targeted genes in squamous cell + Last Modified: 20241027163427 + Organism: Homo sapiens + + + diff --git a/pathways/WP3893/WP3893-datanodes.tsv b/pathways/WP3893/WP3893-datanodes.tsv index bcf6ce383..e4a5fea01 100644 --- a/pathways/WP3893/WP3893-datanodes.tsv +++ b/pathways/WP3893/WP3893-datanodes.tsv @@ -9,25 +9,26 @@ T-bet GeneProduct ensembl:ENSG00000073861 "" ensembl:ENSG00000073861 ncbigene:30 AHR GeneProduct ensembl:ENSG00000106546 "" ensembl:ENSG00000106546 ncbigene:196 hgnc.symbol:AHR uniprot:A0A2R8Y7G1;uniprot:P35869;uniprot:A0A024R9Z8 IFNG GeneProduct ensembl:ENSG00000111537 "" ensembl:ENSG00000111537 ncbigene:3458 hgnc.symbol:IFNG uniprot:A0A7R8GUN6;uniprot:P01579 IL6 GeneProduct ensembl:ENSG00000136244 "" ensembl:ENSG00000136244 ncbigene:3569 hgnc.symbol:IL6 uniprot:B5MCZ3;uniprot:C9J5B0;uniprot:B5MC21;uniprot:B4DNV3;uniprot:P05231;uniprot:B5MC14;uniprot:Q75MH2 -IL-7 GeneProduct ensembl:ENSG00000104432 "" ensembl:ENSG00000104432 ncbigene:3574 hgnc.symbol:IL7 uniprot:A0A0A0MTG5;uniprot:Q5FBX5;uniprot:Q5FBY6;uniprot:Q5FBY3;uniprot:P13232 +IL7 GeneProduct ensembl:ENSG00000104432 "" ensembl:ENSG00000104432 ncbigene:3574 hgnc.symbol:IL7 uniprot:A0A0A0MTG5;uniprot:Q5FBX5;uniprot:Q5FBY6;uniprot:Q5FBY3;uniprot:P13232 BCL11B GeneProduct ensembl:ENSG00000127152 "" ensembl:ENSG00000127152 ncbigene:64919 hgnc.symbol:BCL11B uniprot:L8B7P7;uniprot:Q9C0K0;uniprot:L8B567;uniprot:D3YTK1 GFI1 GeneProduct ensembl:ENSG00000162676 "" ensembl:ENSG00000162676 ncbigene:2672 hgnc.symbol:GFI1 uniprot:Q99684 TCF1 GeneProduct ensembl:ENSG00000135100 "" ensembl:ENSG00000135100 ncbigene:6927 hgnc.symbol:HNF1A uniprot:H0YND5;uniprot:A0A0A0MQU7;uniprot:A0A0A0MTK8;uniprot:F5H3Z5;uniprot:U3KQS6;uniprot:P20823;uniprot:F5H0K0 NFIL3 GeneProduct ensembl:ENSG00000165030 "" ensembl:ENSG00000165030 ncbigene:4783 hgnc.symbol:NFIL3 uniprot:Q16649;uniprot:A0A024R241 IL13 GeneProduct ensembl:ENSG00000169194 "" ensembl:ENSG00000169194 ncbigene:3596 hgnc.symbol:IL13 uniprot:P35225 -IL-4 GeneProduct ensembl:ENSG00000113520 "" ensembl:ENSG00000113520 ncbigene:3565 hgnc.symbol:IL4 uniprot:D4HNR6;uniprot:Q5FC01;uniprot:U3LVN1;uniprot:P05112 +IL4 GeneProduct ensembl:ENSG00000113520 "" ensembl:ENSG00000113520 ncbigene:3565 hgnc.symbol:IL4 uniprot:D4HNR6;uniprot:Q5FC01;uniprot:U3LVN1;uniprot:P05112 PLZF GeneProduct ensembl:ENSG00000109906 "" ensembl:ENSG00000109906 ncbigene:7704 hgnc.symbol:ZBTB16 uniprot:A0A804HJ45;uniprot:A0A804HIC1;uniprot:A0A024R3C6;uniprot:Q05516;uniprot:H0YGW2;uniprot:A0A0S2Z4J5;uniprot:F5H6C3 IL17A GeneProduct ensembl:ENSG00000112115 "" ensembl:ENSG00000112115 ncbigene:3605 hgnc.symbol:IL17A uniprot:Q16552 IL18 GeneProduct ensembl:ENSG00000150782 "" ensembl:ENSG00000150782 ncbigene:3606 hgnc.symbol:IL18 uniprot:A0A024R3E0;uniprot:Q14116 TOX GeneProduct ensembl:ENSG00000198846 "" ensembl:ENSG00000198846 ncbigene:9760 hgnc.symbol:TOX uniprot:O94900 -IL-25 GeneProduct ensembl:ENSG00000166090 "" ensembl:ENSG00000166090 ncbigene:64806 hgnc.symbol:IL25 uniprot:Q9H293 +IL25 GeneProduct ensembl:ENSG00000166090 "" ensembl:ENSG00000166090 ncbigene:64806 hgnc.symbol:IL25 uniprot:Q9H293 IL23A GeneProduct ensembl:ENSG00000110944 "" ensembl:ENSG00000110944 ncbigene:51561 hgnc.symbol:IL23A uniprot:Q9NPF7 IL22 GeneProduct ensembl:ENSG00000127318 "" ensembl:ENSG00000127318 ncbigene:50616 hgnc.symbol:IL22 uniprot:Q9GZX6;uniprot:A0A7R8C389 AREG GeneProduct ensembl:ENSG00000109321 "" ensembl:ENSG00000109321 ncbigene:374 hgnc.symbol:AREG uniprot:P15514;uniprot:D6RFX5 EOMES GeneProduct ensembl:ENSG00000163508 "" ensembl:ENSG00000163508 ncbigene:8320 hgnc.symbol:EOMES uniprot:O95936 RORA GeneProduct ensembl:ENSG00000069667 "" ensembl:ENSG00000069667 ncbigene:6095 hgnc.symbol:RORA uniprot:A0A0C4DFP5;uniprot:H0YLS5;uniprot:P35398;uniprot:H0YII6;uniprot:A0A0C4DG53;uniprot:A0A087X2G0 -IL-33 GeneProduct ensembl:ENSG00000137033 "" ensembl:ENSG00000137033 ncbigene:90865 hgnc.symbol:IL33 uniprot:O95760 +IL33 GeneProduct ensembl:ENSG00000137033 "" ensembl:ENSG00000137033 ncbigene:90865 hgnc.symbol:IL33 uniprot:O95760 TSLP GeneProduct ensembl:ENSG00000145777 "" ensembl:ENSG00000145777 ncbigene:85480 hgnc.symbol:TSLP uniprot:A0A0C4DG43;uniprot:Q969D9 -IL-5 GeneProduct ensembl:ENSG00000113525 "" ensembl:ENSG00000113525 ncbigene:3567 hgnc.symbol:IL5 uniprot:C9JQP9;uniprot:P05113 -IL-9 GeneProduct ensembl:ENSG00000145839 "" ensembl:ENSG00000145839 ncbigene:3578 hgnc.symbol:IL9 uniprot:P15248 +IL5 GeneProduct ensembl:ENSG00000113525 "" ensembl:ENSG00000113525 ncbigene:3567 hgnc.symbol:IL5 uniprot:C9JQP9;uniprot:P05113 +IL9 GeneProduct ensembl:ENSG00000145839 "" ensembl:ENSG00000145839 ncbigene:3578 hgnc.symbol:IL9 uniprot:P15248 +IL-7 GeneProduct ensembl:ENSG00000104432 "" ensembl:ENSG00000104432 ncbigene:3574 hgnc.symbol:IL7 uniprot:A0A0A0MTG5;uniprot:Q5FBX5;uniprot:Q5FBY6;uniprot:Q5FBY3;uniprot:P13232 IL12B GeneProduct ensembl:ENSG00000113302 "" ensembl:ENSG00000113302 ncbigene:3593 hgnc.symbol:IL12B uniprot:P29460 diff --git a/pathways/WP3893/WP3893.gpml b/pathways/WP3893/WP3893.gpml index 13414233d..76981684f 100644 --- a/pathways/WP3893/WP3893.gpml +++ b/pathways/WP3893/WP3893.gpml @@ -1,5 +1,5 @@ - + Development and heterogeneity of the innate lymphoid cell (ILC) family. ILCs develop from distinct progenitors in the fetal liver or bone marrow and then develop into mature ILCs in the periphery. Different transcription factors and cytokines are involved in the development of the three groups of mature ILCs. All ILCs develop from CLPs, which can differentiate into NKps or CHILPs. CHILPs can further differentiate into LTi cells through α4β7+ populations or into other ILC populations through differentiation into ILCps. ILC1s express T-bet, are responsive to IL-12, and produce IFN-γ and/or TNF. ILC2s highly express GATA3, are responsive to IL-25, IL-33 and TSLP, and produce IL-4, IL-5, IL-9, IL-13 and amphiregulin. ILC3s express ROR-γt, are responsive to IL-1β and IL-23, and produce IL-17 and/or IL-22. Proteins on this pathway have targeted assays available via the [https://assays.cancer.gov/available_assays?wp_id=WP3893 CPTAC Assay Portal] @@ -53,7 +53,7 @@ Proteins on this pathway have targeted assays available via the [https://assays. - + @@ -81,7 +81,7 @@ Proteins on this pathway have targeted assays available via the [https://assays. - + @@ -105,7 +105,7 @@ Proteins on this pathway have targeted assays available via the [https://assays. - + @@ -149,7 +149,7 @@ Proteins on this pathway have targeted assays available via the [https://assays. - + @@ -157,15 +157,15 @@ Proteins on this pathway have targeted assays available via the [https://assays. - + - + - + @@ -512,7 +512,7 @@ Proteins on this pathway have targeted assays available via the [https://assays. - diff --git a/pathways/WP3893/WP3893.json b/pathways/WP3893/WP3893.json index d2c09a926..73f13e3b6 100644 --- a/pathways/WP3893/WP3893.json +++ b/pathways/WP3893/WP3893.json @@ -128,7 +128,7 @@ "stroke": "#000000", "strokeWidth": 1, "textAlign": "center", - "textContent": "IL-33", + "textContent": "IL33", "textDecoration": "none", "textOverflow": "clip", "type": [ @@ -137,7 +137,7 @@ "Ensembl:ENSG00000137033", "GeneProduct", "CompactIdentifier:ensembl:ENSG00000137033", - "IL-33", + "IL33", "Ensembl:ENSG00000137033", "Entrez Gene:90865", "HGNC:IL33", @@ -2095,7 +2095,7 @@ "stroke": "#000000", "strokeWidth": 1, "textAlign": "center", - "textContent": "IL-7", + "textContent": "IL7", "textDecoration": "none", "textOverflow": "clip", "type": [ @@ -2104,7 +2104,7 @@ "Ensembl:ENSG00000104432", "GeneProduct", "CompactIdentifier:ensembl:ENSG00000104432", - "IL-7", + "IL7", "Ensembl:ENSG00000104432", "Entrez Gene:3574", "HGNC:IL7", @@ -2202,7 +2202,7 @@ "stroke": "#000000", "strokeWidth": 1, "textAlign": "center", - "textContent": "IL-25", + "textContent": "IL25", "textDecoration": "none", "textOverflow": "clip", "type": [ @@ -2211,7 +2211,7 @@ "Ensembl:ENSG00000166090", "GeneProduct", "CompactIdentifier:ensembl:ENSG00000166090", - "IL-25", + "IL25", "Ensembl:ENSG00000166090", "Entrez Gene:64806", "HGNC:IL25", @@ -2576,7 +2576,7 @@ "stroke": "#000000", "strokeWidth": 1, "textAlign": "center", - "textContent": "IL-5", + "textContent": "IL5", "textDecoration": "none", "textOverflow": "clip", "type": [ @@ -2585,7 +2585,7 @@ "Ensembl:ENSG00000113525", "GeneProduct", "CompactIdentifier:ensembl:ENSG00000113525", - "IL-5", + "IL5", "Ensembl:ENSG00000113525", "Entrez Gene:3567", "HGNC:IL5", @@ -3330,7 +3330,7 @@ "stroke": "#000000", "strokeWidth": 1, "textAlign": "center", - "textContent": "IL-9", + "textContent": "IL9", "textDecoration": "none", "textOverflow": "clip", "type": [ @@ -3339,7 +3339,7 @@ "Ensembl:ENSG00000145839", "GeneProduct", "CompactIdentifier:ensembl:ENSG00000145839", - "IL-9", + "IL9", "Ensembl:ENSG00000145839", "Entrez Gene:3578", "HGNC:IL9", @@ -3411,7 +3411,7 @@ "stroke": "#000000", "strokeWidth": 1, "textAlign": "center", - "textContent": "IL-4", + "textContent": "IL4", "textDecoration": "none", "textOverflow": "clip", "type": [ @@ -3420,7 +3420,7 @@ "Ensembl:ENSG00000113520", "GeneProduct", "CompactIdentifier:ensembl:ENSG00000113520", - "IL-4", + "IL4", "Ensembl:ENSG00000113520", "Entrez Gene:3565", "HGNC:IL4", @@ -4168,7 +4168,7 @@ "stroke": "#000000", "strokeWidth": 1, "textAlign": "center", - "textContent": "IL-25", + "textContent": "IL25", "textDecoration": "none", "textOverflow": "clip", "type": [ @@ -4177,7 +4177,7 @@ "Ensembl:ENSG00000166090", "GeneProduct", "CompactIdentifier:ensembl:ENSG00000166090", - "IL-25", + "IL25", "Ensembl:ENSG00000166090", "Entrez Gene:64806", "HGNC:IL25", @@ -4396,7 +4396,7 @@ "stroke": "#000000", "strokeWidth": 0, "textAlign": "center", - "textContent": "ILC: Innate Lymphoid Cell", + "textContent": "ILC: Innate lymphoid cell", "textDecoration": "none", "textOverflow": "clip", "type": [ @@ -7411,7 +7411,7 @@ "be026", "d5d6d" ], - "dataSourceVersion": "WP3893_r129544", + "dataSourceVersion": "WP3893_r135705", "displayName": "Development and heterogeneity of the ILC family", "drawAs": "rect", "fill": "white", @@ -7421,7 +7421,7 @@ "height": 722.8067226890762, "id": "WP3893", "kaavioType": "Group", - "lastModified": "20240510160121", + "lastModified": "20241027164530", "name": "Development and heterogeneity of the ILC family", "organism": "Homo sapiens", "padding": 5, @@ -7430,7 +7430,7 @@ "stroke": "black", "strokeWidth": 0, "textAlign": "left", - "textContent": "Name: Development and heterogeneity of the ILC family\nLast Modified: 20240510160121\nOrganism: Homo sapiens", + "textContent": "Name: Development and heterogeneity of the ILC family\nLast Modified: 20241027164530\nOrganism: Homo sapiens", "type": [ "Pathway", "http://identifiers.org/pw/PW:0000004" diff --git a/pathways/WP3893/WP3893.png b/pathways/WP3893/WP3893.png index d725bd61b..146153811 100644 Binary files a/pathways/WP3893/WP3893.png and b/pathways/WP3893/WP3893.png differ diff --git a/pathways/WP3893/WP3893.svg b/pathways/WP3893/WP3893.svg index a76d360f1..aad70c742 100644 --- a/pathways/WP3893/WP3893.svg +++ b/pathways/WP3893/WP3893.svg @@ -472,7 +472,7 @@ - + @@ -783,10 +783,10 @@ negative - + - ILC: Innate Lymphoid Cell + ILC: Innate lymphoid cell @@ -895,10 +895,10 @@ IL17A - + - IL-25 + IL25 @@ -1002,10 +1002,10 @@ GATA3 - + - IL-7 + IL7 @@ -1107,10 +1107,10 @@ IL13 - + - IL-4 + IL4 @@ -1119,16 +1119,16 @@ AREG - + - IL-5 + IL5 - + - IL-9 + IL9 @@ -1264,10 +1264,10 @@ - + - IL-33 + IL33 @@ -1276,10 +1276,10 @@ TSLP - + - IL-25 + IL25 @@ -1364,7 +1364,7 @@ Name: Development and heterogeneity of the ILC family - Last Modified: 20240510160121 + Last Modified: 20241027164530 Organism: Homo sapiens diff --git a/pathways/WP5046/WP5046-bibliography.tsv b/pathways/WP5046/WP5046-bibliography.tsv index fff8ba1ae..c725a88d7 100644 --- a/pathways/WP5046/WP5046-bibliography.tsv +++ b/pathways/WP5046/WP5046-bibliography.tsv @@ -1,10 +1,10 @@ ID Database Citation -19052657 Pubmed "Horenstein AL, Sizzano F, Lusso R, Besso FG, Ferrero E, Deaglio S, et al. CD38 and CD157 ectoenzymes mark cell subsets in the human corneal limbus. Mol Med. 2009;15(3–4):76–84. PubMed Europe PMC Scholia" -20725615 Pubmed "Surjana D, Halliday GM, Damian DL. Role of nicotinamide in DNA damage, mutagenesis, and DNA repair. J Nucleic Acids. 2010 Jul 25;2010:157591. PubMed Europe PMC Scholia" -21646373 Pubmed "Ohanna M, Giuliano S, Bonet C, Imbert V, Hofman V, Zangari J, et al. Senescent cells develop a PARP-1 and nuclear factor-{kappa}B-associated secretome (PNAS). Genes Dev. 2011 Jun 15;25(12):1245–61. PubMed Europe PMC Scholia" -22971926 Pubmed "Lee S-M, Dho SH, Ju S-K, Maeng J-S, Kim J-Y, Kwon K-S. Cytosolic malate dehydrogenase regulates senescence in human fibroblasts. Biogerontology. 2012 Oct;13(5):525–36. PubMed Europe PMC Scholia" -26009982 Pubmed "Takebayashi S-I, Tanaka H, Hino S, Nakatsu Y, Igata T, Sakamoto A, et al. Retinoblastoma protein promotes oxidative phosphorylation through upregulation of glycolytic genes in oncogene-induced senescent cells. Aging Cell. 2015 Aug;14(4):689–97. PubMed Europe PMC Scholia" -26686024 Pubmed "Wiley CD, Velarde MC, Lecot P, Liu S, Sarnoski EA, Freund A, et al. Mitochondrial Dysfunction Induces Senescence with a Distinct Secretory Phenotype. Cell Metab. 2016 Feb 9;23(2):303–14. PubMed Europe PMC Scholia" -26890602 Pubmed "Han X, Tai H, Wang X, Wang Z, Zhou J, Wei X, et al. AMPK activation protects cells from oxidative stress-induced senescence via autophagic flux restoration and intracellular NAD(+) elevation. Aging Cell. 2016 Jun;15(3):416–27. PubMed Europe PMC Scholia" -27304503 Pubmed "Wiley CD, Campisi J. From Ancient Pathways to Aging Cells-Connecting Metabolism and Cellular Senescence. Cell Metab. 2016 Jun 14;23(6):1013–21. PubMed Europe PMC Scholia" -30778219 Pubmed "Nacarelli T, Lau L, Fukumoto T, Zundell J, Fatkhutdinov N, Wu S, et al. NAD+ metabolism governs the proinflammatory senescence-associated secretome. Nat Cell Biol. 2019 Mar;21(3):397–407. PubMed Europe PMC Scholia" +19052657 Pubmed "CD38 and CD157 ectoenzymes mark cell subsets in the human corneal limbus. Horenstein AL, Sizzano F, Lusso R, Besso FG, Ferrero E, Deaglio S, et al. Mol Med. 2009;15(3–4):76–84. PubMed Europe PMC Scholia" +20725615 Pubmed "Role of nicotinamide in DNA damage, mutagenesis, and DNA repair. Surjana D, Halliday GM, Damian DL. J Nucleic Acids. 2010 Jul 25;2010:157591. PubMed Europe PMC Scholia" +21646373 Pubmed "Senescent cells develop a PARP-1 and nuclear factor-{kappa}B-associated secretome (PNAS). Ohanna M, Giuliano S, Bonet C, Imbert V, Hofman V, Zangari J, et al. Genes Dev. 2011 Jun 15;25(12):1245–61. PubMed Europe PMC Scholia" +22971926 Pubmed "Cytosolic malate dehydrogenase regulates senescence in human fibroblasts. Lee SM, Dho SH, Ju SK, Maeng JS, Kim JY, Kwon KS. Biogerontology. 2012 Oct;13(5):525–36. PubMed Europe PMC Scholia" +26009982 Pubmed "Retinoblastoma protein promotes oxidative phosphorylation through upregulation of glycolytic genes in oncogene-induced senescent cells. Takebayashi SI, Tanaka H, Hino S, Nakatsu Y, Igata T, Sakamoto A, et al. Aging Cell. 2015 Aug;14(4):689–97. PubMed Europe PMC Scholia" +26686024 Pubmed "Mitochondrial Dysfunction Induces Senescence with a Distinct Secretory Phenotype. Wiley CD, Velarde MC, Lecot P, Liu S, Sarnoski EA, Freund A, et al. Cell Metab. 2016 Feb 9;23(2):303–14. PubMed Europe PMC Scholia" +26890602 Pubmed "AMPK activation protects cells from oxidative stress-induced senescence via autophagic flux restoration and intracellular NAD(+) elevation. Han X, Tai H, Wang X, Wang Z, Zhou J, Wei X, et al. Aging Cell. 2016 Jun;15(3):416–27. PubMed Europe PMC Scholia" +27304503 Pubmed "From Ancient Pathways to Aging Cells-Connecting Metabolism and Cellular Senescence. Wiley CD, Campisi J. Cell Metab. 2016 Jun 14;23(6):1013–21. PubMed Europe PMC Scholia" +30778219 Pubmed "NAD+ metabolism governs the proinflammatory senescence-associated secretome. Nacarelli T, Lau L, Fukumoto T, Zundell J, Fatkhutdinov N, Wu S, et al. Nat Cell Biol. 2019 Mar;21(3):397–407. PubMed Europe PMC Scholia" diff --git a/pathways/WP5046/WP5046-datanodes.tsv b/pathways/WP5046/WP5046-datanodes.tsv index f61903cb5..5b223eb1d 100644 --- a/pathways/WP5046/WP5046-datanodes.tsv +++ b/pathways/WP5046/WP5046-datanodes.tsv @@ -4,12 +4,12 @@ Aspartate Metabolite chebi:35391 "" wikidata:Q27104311 chebi:35391 inchikey: Malate Metabolite chebi:30797 "" wikidata:Q27104150 chebi:30797 inchikey:BJEPYKJPYRNKOW-REOHCLBHSA-N pubchem.compound:222656 chemspider:193317 hmdb:HMDB0000156 kegg.compound:C00149 OAA Metabolite chebi:132560 "" chebi:132560 PRPP Metabolite chebi:17111 "" wikidata:Q420633 chebi:17111 inchikey:PQGCEDQWHSBAJP-TXICZTDVSA-N pubchem.compound:7339 chemspider:7062 hmdb:HMDB0000280 kegg.compound:C00119 -pyruvate Metabolite chebi:15361 "" wikidata:Q27089397 chebi:15361 inchikey:LCTONWCANYUPML-UHFFFAOYSA-M pubchem.compound:107735 chemspider:96901 kegg.compound:C00022 +Pyruvate Metabolite chebi:15361 "" wikidata:Q27089397 chebi:15361 inchikey:LCTONWCANYUPML-UHFFFAOYSA-M pubchem.compound:107735 chemspider:96901 kegg.compound:C00022 lactate Metabolite chebi:24996 "" wikidata:Q27895931 chebi:24996 inchikey:JVTAAEKCZFNVCJ-UHFFFAOYSA-M pubchem.compound:91435 chemspider:82564 kegg.compound:C01432 PGM Metabolite chebi:33365 "" chebi:33365 NADH Metabolite hmdb:HMDB01487 "" wikidata:Q26987453 chebi:16908 inchikey:BOPGDPNILDQYTO-NNYOXOHSSA-N pubchem.compound:439153 chemspider:903;chemspider:388299 hmdb:HMDB0001487 kegg.compound:C00004 NAD Metabolite hmdb:HMDB00902 "" wikidata:Q71535049;wikidata:Q26987253 chebi:15846;chebi:44215 inchikey:BAWFJGJZGIEFAR-NNYOXOHSSA-O;inchikey:BAWFJGJZGIEFAR-NNYOXOHSSA-N pubchem.compound:5892;pubchem.compound:5893;pubchem.compound:5288979;pubchem.compound:10897651;pubchem.compound:73415790 chemspider:5682 hmdb:HMDB0000902 kegg.compound:C00003 -nicotinamide Metabolite chebi:17154 "" wikidata:Q192423 chebi:17154 inchikey:DFPAKSUCGFBDDF-UHFFFAOYSA-N pubchem.compound:936 chemspider:911 hmdb:HMDB0001406 kegg.compound:C00153 +Nicotinamide Metabolite chebi:17154 "" wikidata:Q192423 chebi:17154 inchikey:DFPAKSUCGFBDDF-UHFFFAOYSA-N pubchem.compound:936 chemspider:911 hmdb:HMDB0001406 kegg.compound:C00153 IL8 Metabolite chebi:138181 "" wikidata:Q421859 chebi:138181 SCO2 GeneProduct ensembl:ENSG00000130489 "" MDH2 GeneProduct ensembl:ENSG00000146701 "" ensembl:ENSG00000146701 ncbigene:4191 hgnc.symbol:MDH2 uniprot:U3KQ63;uniprot:A0A024R4K3;uniprot:G3XAL0;uniprot:P40926 @@ -29,6 +29,7 @@ NAMPT GeneProduct ensembl:ENSG00000105835 "" ensembl:ENSG00000105835 ncbigene:10 TP53 GeneProduct ensembl:ENSG00000141510 "" ensembl:ENSG00000141510 ncbigene:7157 hgnc.symbol:TP53 uniprot:E9PFT5;uniprot:A0A087WXZ1;uniprot:P04637;uniprot:A0A087X1Q1;uniprot:E7ESS1;uniprot:E7EMR6;uniprot:E7EQX7;uniprot:A0A0U1RQC9;uniprot:J3KP33;uniprot:H2EHT1;uniprot:I3L0W9;uniprot:K7PPA8;uniprot:S4R334;uniprot:A0A087WT22;uniprot:E9PCY9 SIRT3 GeneProduct ensembl:ENSG00000142082 "" ensembl:ENSG00000142082 ncbigene:23410 hgnc.symbol:SIRT3 uniprot:B7WNN4;uniprot:E9PR48;uniprot:E9PIT6;uniprot:E9PM75;uniprot:E9PM52;uniprot:E9PJS6;uniprot:E9PNA0;uniprot:E9PK80;uniprot:E9PN58;uniprot:Q9NTG7 MDH1 GeneProduct ensembl:ENSG00000014641 "" ensembl:ENSG00000014641 ncbigene:4190 hgnc.symbol:MDH1 uniprot:C9IZI0;uniprot:B8ZZ51;uniprot:V9HWF2;uniprot:P40925;uniprot:B9A041;uniprot:C9JRL4;uniprot:C9JLV6;uniprot:F8WFC2;uniprot:A0A5K1VW95;uniprot:C9JF79 +TNFA GeneProduct ensembl:ENSG000002328 "" G6PDH Protein ensembl:ENSG00000160211 "" ensembl:ENSG00000160211 ncbigene:2539 hgnc.symbol:G6PD uniprot:E7EM57;uniprot:P11413;uniprot:E7EUI8;uniprot:E9PD92;uniprot:A0A384NL00 GLUT4 Protein ensembl:ENSG00000181856 "" ensembl:ENSG00000181856 ncbigene:6517 hgnc.symbol:SLC2A4 uniprot:I3L2R4;uniprot:I3L1S2;uniprot:P14672;uniprot:F5H081 GLUT1 Protein ensembl:ENSG00000117394 "" ensembl:ENSG00000117394 ncbigene:6513 hgnc.symbol:SLC2A1 uniprot:P11166;uniprot:A0A6Q8PFI8;uniprot:A0A0D9SFK9;uniprot:A0A0D9SG74;uniprot:A0A1W2PQ59;uniprot:A6NL68 @@ -36,4 +37,3 @@ HuR Protein ensembl:ENSG00000066044 "" ensembl:ENSG00000066044 ncbigene:1994 hgn Transcription factor p65 Protein uniprot:Q04206 "" ensembl:ENSG00000173039 ncbigene:5970 hgnc.symbol:RELA uniprot:E9PNV4;uniprot:E9PRX2;uniprot:E9PJR1;uniprot:E9PJZ9;uniprot:E9PKV4;uniprot:A0A087X0W8;uniprot:E9PM47;uniprot:Q04206;uniprot:E9PI38;uniprot:E9PQS6;uniprot:E9PKH5;uniprot:E9PNK5;uniprot:Q2TAM5;uniprot:E9PMD5;uniprot:H0YCB4;uniprot:E9PSE4 IL-10 Protein ensembl:ENSGALG00000000892 "" AMPKa1 Protein ensembl:ENSG00000132356 "" ensembl:ENSG00000132356 ncbigene:5562 hgnc.symbol:PRKAA1 uniprot:Q96E92;uniprot:Q13131 -TNF-a Protein ensembl:ENSG000002328 "" diff --git a/pathways/WP5046/WP5046.gpml b/pathways/WP5046/WP5046.gpml index e9075cf82..d1280f6f4 100644 --- a/pathways/WP5046/WP5046.gpml +++ b/pathways/WP5046/WP5046.gpml @@ -1,5 +1,5 @@ - + The uppermost part of the pathway includes part of the general NAM salvage pathway in the cytosol as it is relevant to senescence-induced changes to NAD metabolism. In this pathway, NAD levels are maintained through recycling back to NAD from nicotinamide (NAM) and nicotinamide mononucleotide (NMN) (Braidy et al., 2019). The conversion from NAM to NMN is catalyzed by nicotinamide phosphoribosyltransferase (NAMPT), while the conversion from NMN to NAD is catalyzed by nicotinamide mononucleotide adenylyl transferases (NMNATs). Other sources, such as nicotinic acid (NA) and nicotinamid riboside (NR), are not shown here as they are not affected by senescence, at least from current research. OIS-specific interactions are highlighted in orange, while MiDAS-specific interactions are highlighted in purple. General interactions for both (or other senescent types) remain a black color. The OIS pathway, induced by Ras singalling in this case, results in the upregulation of HMGA1, and stimulation of the NAMPT enzyme (Nacarelli et al., 2019). Resulting increased levels of NMN (the direct metabolite of NAMPT) translate to increased NAD levels, and a high NAD-NADH ratio. This leads to decreased ADP-ATP levels, which causes a decreased phosphorylated AMPK expression (Nacarelli et al., 2019). This interaction causes increased p38 and p65 activation, and increased NF-κB activity. The NF-κB signalling pathway has been known to play a key role in the promotion of the proinflammatory SASP (Freund et al., 2011). Furthermore, this is correlated with increased expression of interleukins IL1B, IL6 and IL8, all key factors in the proinflammatory wave of the SASP. In addition, Nacarelli et al. (2019) found that the proinflammatory environment created as a result of the increased NAD-NADH ratio leads to acceleration of cancer progression. NAMPT upregulation through HMGA1 also resulted in the expression of senescence markers SA-ß-gal, p16 and p21. The resulting phenotype from this high NAD-NADH ratio is a high proinflammatory SASP. @@ -8,392 +8,389 @@ Malate is another important metabolite in redox reactions and in many senescence Mitochondrial dysfunction-associated senescence (MiDAS), on the other hand, causes a decrease in the NAD-NADH ratio, which induces three main responses: (1) the inhibition of sirtuins, (2) the activation of AMPK and (3) the inhibition of PARP which blocks the NF-kB pathway. First, low levels of NAD+ decrease sirtuin activity. A decrease in the activity of SIRT3 and SIRT5, located in the mitochondria, is associated with the activation of cell senescence (Wiley et al., 2016)). Second, a decreased NAD+/NADH ratio activates AMPK and p53, which inhibits the RNA binding protein Hu antigen R (HuR) from degrading the mRNAs encoding the cyclin-dependent kinase inhibitors, p21 and p16INK4a. This increases the activity of the pRB tumor suppressor, resulting in cell proliferation and growth arrest ((Wiley et al., 2016)). Additionally, p53 activation leads to the release of SASPs that lack IL-1-dependent factors but include the secretion of anti-inflammatory cytokine IL-10 and high levels of the pro-inflammatory cytokines CCL27 and TNF-α (Wiley et al., 2016). The activation of p53 also reduces glycolysis and promotes mitochondrial respiration, by inhibiting phosphoglycercate mutase (PGM) and inducing the expression of synthesis of cytochrome c oxidase 2 (SCO2). Furthermore, p53 activation inhibits the pentose phosphate pathway (PPP) by binding to glucose-6-phosphate dehydrogenase (G6PDH). Lastly, the low NAD+,NADH ratio inhibits ADP-ribose donor for poly-ADP ribose polymerase (PARP), which consecutively inhibits the NF-kB pathway. A downregulated NF-κB pathway then contributes to the pathogenic processes of various inflammatory diseases as well as the expression of various proinflammatory SASPs (Liu et al., 2017). -As visible in this pathway, when senescence is induced by either OIS or MiDAS distinguishable effects on NAD metabolism are evident. Not only do these stimuli release distinct SASPs, but they exhibit distinct responses on the NAD-NADH ratio and subsequent related pathways. While MiDAS leads to a decrease in the NAD-NADH ratio, OIS causes an increase in this ratio and the NAD+ levels. - - - +As visible in this pathway, when senescence is induced by either OIS or MiDAS distinguishable effects on NAD metabolism are evident. Not only do these stimuli release distinct SASPs, but they exhibit distinct responses on the NAD-NADH ratio and subsequent related pathways. While MiDAS leads to a decrease in the NAD-NADH ratio, OIS causes an increase in this ratio and the NAD+ levels. + + + + - + - + - + - + - + - + - + - + - + - + - + - - + + - + - + - + - + - + - + - + - + - + - + - + - + - - + + - + - + - + - + - + - + - + - - + + - + - + - + - + - + - + - + - + - + - - + + - - + + - + - - + + - + - + - + - - + + - - + + - + - - - - a17 c5d - - + + c25 - - + + da9 - - + + c5d - - - + + + da9 - - + + - - + + c5d - - - - - + + + + + c5d - - + + - - + + da9 - - + + da9 - - + + da9 - - + + - - + + - - + + - - + + - - + + - - + + - - + + da9 - - + + - - + + - - + + - - + + @@ -401,122 +398,122 @@ As visible in this pathway, when senescence is induced by either OIS or MiDAS di da9 - - - + + + c5d - - + + - - + + - - - + + + - - + + - - + + c25 - - - + + + - - + + - - + + c25 - - - + + + - - + + - - + + - - + + da9 - - + + - - + + - - + + @@ -524,79 +521,79 @@ As visible in this pathway, when senescence is induced by either OIS or MiDAS di c5d c9e - - - + + + - - + + - - + + da9 - - + + - - + + da9 - - + + c5d - - + + c25 - - + + c25 - - - + + + - - + + @@ -604,83 +601,83 @@ As visible in this pathway, when senescence is induced by either OIS or MiDAS di da9 - - + + f2a - - - - + + + + - - - + + + - - + + - - + + da9 - - + + da9 - - + + - - - + + + c9e - - + + c5d - - - - - + + + + + @@ -688,15 +685,15 @@ As visible in this pathway, when senescence is induced by either OIS or MiDAS di d81 da9 - - + + - - + + @@ -704,182 +701,219 @@ As visible in this pathway, when senescence is induced by either OIS or MiDAS di ab5 ae9 - - - + + + - - + + c25 - - + + - - - + + + - - + + - - - + + + - - + + - - + + da9 - - + + - - + + - - + + - - - + + + - + diff --git a/pathways/WP5046/WP5046.json b/pathways/WP5046/WP5046.json index 822603dda..751876853 100644 --- a/pathways/WP5046/WP5046.json +++ b/pathways/WP5046/WP5046.json @@ -1,5 +1,69 @@ { "entitiesById": { + "a09de": { + "contains": [ + "c3172", + "de749", + "f9b7a" + ], + "drawAs": "none", + "fill": "transparent", + "fillOpacity": 0.1, + "fontSize": 1, + "fontWeight": "bold", + "gpmlElementName": "Group", + "height": 94.26460481099502, + "id": "a09de", + "kaavioType": "Group", + "padding": 8, + "stroke": "#808080", + "strokeDasharray": "5,3", + "strokeWidth": 0, + "textAlign": "center", + "type": [ + "Group", + "GroupGroup" + ], + "verticalAlign": "middle", + "width": 106, + "x": 296.5873077046586, + "y": 954.8951890034368, + "zIndex": 32768 + }, + "a0cef": { + "drawAs": "rect", + "fill": "transparent", + "fontFamily": "Arial", + "fontSize": 12, + "fontStyle": "normal", + "fontWeight": "normal", + "gpmlElementName": "Shape", + "height": 229.25, + "id": "a0cef", + "kaavioType": "SingleFreeNode", + "lineHeight": 1.1, + "overflow": "hidden", + "padding": 8, + "rotation": 0, + "rx": 15, + "ry": 15, + "stroke": "#000000", + "strokeDasharray": "5,3", + "strokeWidth": 1, + "textAlign": "center", + "textDecoration": "none", + "textOverflow": "clip", + "type": [ + "Shape", + "SingleFreeNode" + ], + "verticalAlign": "middle", + "whiteSpace": "pre", + "width": 235.25, + "x": 1798.75, + "y": 118.75, + "zIndex": 16384 + }, "a14b5": { "drawAs": "rect", "fill": "#ffffff", @@ -24,16 +88,16 @@ "DataNode", "SingleFreeNode", "Ensembl:ENSG00000139687", - 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"bee6c", - "c2134", - "d7fcf", - "acc64", - "da84a", + "a09de", + "c8142", + "caabf", + "f900a", + "fa83c", "b3b2f", "e5592", "b6de2", @@ -8252,24 +8150,23 @@ "id8400c5f6", "idcecd82e8", "db94a", - "e4a6c", - "dd9a2", "bfc00", "c33b0", "idc80a552b", - "id4ca152dd" + "id4ca152dd", + "d73bd" ], - "dataSourceVersion": "WP5046_r118987", + "dataSourceVersion": "WP5046_r135695", "displayName": "NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence", "drawAs": "rect", "fill": "white", "fontSize": 12, "fontWeight": "bold", "gpmlElementName": "Pathway", - "height": 1741.6059379217274, + "height": 1648.2726045883946, "id": "WP5046", "kaavioType": "Group", - "lastModified": "20210607065215", + "lastModified": "20241027122259", "name": "NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence", "organism": "Homo sapiens", "padding": 5, @@ -8278,14 +8175,14 @@ "stroke": "black", "strokeWidth": 0, "textAlign": "left", - "textContent": "Name: NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence\nLast Modified: 20210607065215\nOrganism: Homo sapiens", + "textContent": "Name: NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence\nLast Modified: 20241027122259\nOrganism: Homo sapiens", "type": [ "Pathway", "http://identifiers.org/pw/PW:0000277", "http://identifiers.org/pw/PW:0002580" ], "verticalAlign": "top", - "width": 2325.2258971781666, + "width": 2064, "x": 0, "y": 0, "zIndex": 0 diff --git a/pathways/WP5046/WP5046.png b/pathways/WP5046/WP5046.png index 3bafdc898..98e188aca 100644 Binary files a/pathways/WP5046/WP5046.png and b/pathways/WP5046/WP5046.png differ diff --git a/pathways/WP5046/WP5046.svg b/pathways/WP5046/WP5046.svg index fb410d097..56142dabc 100644 --- a/pathways/WP5046/WP5046.svg +++ b/pathways/WP5046/WP5046.svg @@ -1,5 +1,5 @@ - + @@ -10,70 +10,70 @@ - + - + - + - + - + - + - - - - - - - + - + - + - + - + + + + + + + - + - + - + - + - + - + - + - + - + @@ -490,652 +490,668 @@ - - + + - - + + - - + + - - + + - - + + - - + + - - + + - - + + - + - - + + - + - - + + - + - - + + - - + + - - + + - + - + - + - + - + - - + + - + - - + + - - + + - - + + - - + + - + - + - + - - + + - - + + - - + + - + - - + + - + - - + + - - + + - - + + - + - - + + - - + + - - + + - - + + - - + + - - + + - - + + - - + + - - + + - - + + - - - + + + - - + + - + - - + + - - + + - + - - + + - - + + - - + + - + - - + + - + - + - - + + - - + + - - + + - + - - + + - - + + - - + + - - + + - - + + - - + + - - + + - + + + + - + - + - + + + + Common for + both pathways + + + + + + Legend + + + + + + Oncogene induced + senescence + + + - Growth Arrest + Growth arrest - - - - Pentose Phospate - Pathway + + + + Pentose phospate + pathway - + MITOCHONDRIA - + - Cell Senescence + Cell senescence - - - - Common for - both pathways - - - + - Mitochondrial Dysfunction- - Associated Senescence + Mitochondrial dysfunction- + associated senescence - + Promotion of - Cancer Progression + cancer progression - + CYTOPLASM - + pRB - + G6PDH - + GLUT4 - + SCO2 - + MDH2 - + NMN - + GOT2 - + ADP/ATP - + p38 MAPK - + HMGA1 - + Aspartate - - - - Fatty Acid - Beta Oxidation + + + + Fatty acid + beta oxidation - + Malate - + OAA - + GLUT1 - + HuR - + GOT1 - + Transcription factor p65 - + PRPP - + - pyruvate + Pyruvate - + NMNAT2 - + lactate - + PARP1 - + PGM - + - Canonical NF-KB Pathway + Canonical NF-KB pathway - + AMPKa1 - + NAMPT - + TP53 - + NADH - + MDH1 - + Glycolysis - + NAD - + - nicotinamide + Nicotinamide - + - Oncogene Induced Senescence + Oncogene induced senescence - - - + + + CCL27 - + IL-10 - + - TNF-a + TNFA - - + + @@ -1155,8 +1171,8 @@ - - + + @@ -1176,9 +1192,9 @@ - - - + + + SIRT5 @@ -1191,8 +1207,8 @@ - - + + @@ -1206,19 +1222,19 @@ - + High proinflammatory SASP - + Malate - + OAA @@ -1226,83 +1242,76 @@ - + - + - + Aspartate - - - - Mitochondrial Oxidative - Phosphorylation + + + + Mitochondrial oxidative + phosphorylation - + - TCA Cycle + TCA cycle - - + + - - + + - + NAD/NADH - - - - Oncogene Induced - Senescence - - - - - - Mitochondrial Dysfunction- - Associated Senescence - - - + - + - + - + - + + + + + Mitochondrial dysfunction- + associated senescence + + Name: NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence - Last Modified: 20210607065215 + Last Modified: 20241027122259 Organism: Homo sapiens diff --git a/pathways/WP5074/WP5074-datanodes.tsv b/pathways/WP5074/WP5074-datanodes.tsv index da4eb9fcd..485a820f3 100644 --- a/pathways/WP5074/WP5074-datanodes.tsv +++ b/pathways/WP5074/WP5074-datanodes.tsv @@ -2,16 +2,16 @@ Label Type Identifier Comment Ensembl NCBI gene HGNC UniProt Wikidata ChEBI InCh ATP Metabolite chebi:30616 "" wikidata:Q27113900 chebi:30616 inchikey:ZKHQWZAMYRWXGA-KQYNXXCUSA-J pubchem.compound:5461108 chemspider:4574455 HS Metabolite chebi:28815 "" wikidata:Q424668 chebi:28815 hmdb:HMDB0000693 kegg.compound:C00925 IP3 Metabolite chebi:16595 "" wikidata:Q26998374 chebi:16595 inchikey:MMWCIQZXVOZEGG-XJTPDSDZSA-N pubchem.compound:439456 chemspider:388562 hmdb:HMDB0001498 kegg.compound:C01245 -estradiol Metabolite chebi:23965 "" wikidata:Q12415847 chebi:23965 inchikey:VOXZDWNPVJITMN-WKUFJEKOSA-N pubchem.compound:9811784 chemspider:7987537 +Estradiol Metabolite chebi:23965 "" wikidata:Q12415847 chebi:23965 inchikey:VOXZDWNPVJITMN-WKUFJEKOSA-N pubchem.compound:9811784 chemspider:7987537 DAG Metabolite chebi:18035 "" wikidata:Q161466 chebi:18035 kegg.compound:C00165 lipidmaps:LMGL0201 Hypothalamus Metabolite chebi:65307 "" wikidata:Q27133780 chebi:65307 inchikey:QMZRMXQCHRPRQD-SAWSQHHPSA-N pubchem.compound:70678690 chemspider:34999260 Ca2+ Metabolite chebi:29108 "" wikidata:Q23905776 chebi:29108 inchikey:BHPQYMZQTOCNFJ-UHFFFAOYSA-N pubchem.compound:271 chemspider:266 hmdb:HMDB0000464 kegg.compound:C00076 -testosterone Metabolite chebi:17347 "" wikidata:Q1318776 chebi:17347 inchikey:MUMGGOZAMZWBJJ-DYKIIFRCSA-N pubchem.compound:6013 chemspider:5791 hmdb:HMDB0000234 kegg.compound:C00535 lipidmaps:LMST02020002 +Testosterone Metabolite chebi:17347 "" wikidata:Q1318776 chebi:17347 inchikey:MUMGGOZAMZWBJJ-DYKIIFRCSA-N pubchem.compound:6013 chemspider:5791 hmdb:HMDB0000234 kegg.compound:C00535 lipidmaps:LMST02020002 LH Metabolite uniprot:P01229 "" ensembl:ENSG00000104826 ncbigene:3972 hgnc.symbol:LHB uniprot:P01229;uniprot:A0A0F7RQE6 -oestrogen Metabolite chebi:50114 "" wikidata:Q277954 chebi:50114 -testosterone Metabolite chebi:17347 "Estradiol
Progesteron" wikidata:Q1318776 chebi:17347 inchikey:MUMGGOZAMZWBJJ-DYKIIFRCSA-N pubchem.compound:6013 chemspider:5791 hmdb:HMDB0000234 kegg.compound:C00535 lipidmaps:LMST02020002 +Estrogen Metabolite chebi:50114 "" wikidata:Q277954 chebi:50114 +Testosterone Metabolite chebi:17347 "Estradiol
Progesteron" wikidata:Q1318776 chebi:17347 inchikey:MUMGGOZAMZWBJJ-DYKIIFRCSA-N pubchem.compound:6013 chemspider:5791 hmdb:HMDB0000234 kegg.compound:C00535 lipidmaps:LMST02020002 FSH Metabolite chebi:81569 "" wikidata:Q200774 chebi:81569 kegg.compound:C18184 -progesterone Metabolite chebi:17026 "" wikidata:Q26963 chebi:17026 inchikey:RJKFOVLPORLFTN-LEKSSAKUSA-N pubchem.compound:5994 chemspider:5773 hmdb:HMDB0001830 kegg.compound:C00410 lipidmaps:LMST02030159 +Progesterone Metabolite chebi:17026 "" wikidata:Q26963 chebi:17026 inchikey:RJKFOVLPORLFTN-LEKSSAKUSA-N pubchem.compound:5994 chemspider:5773 hmdb:HMDB0001830 kegg.compound:C00410 lipidmaps:LMST02030159 MAPK1 GeneProduct ensembl:ENSG00000100030 "" ensembl:ENSG00000100030 ncbigene:5594 hgnc.symbol:MAPK1 uniprot:P28482;uniprot:Q1HBJ4 PLXND1 GeneProduct uniprot:Q9Y4D7 "" ensembl:ENSG00000004399 ncbigene:23129 hgnc.symbol:PLXND1 uniprot:H0YA64;uniprot:D6RH25;uniprot:H0YAB2;uniprot:Q9Y4D7;uniprot:H0YAM9;uniprot:H0Y9D1 CHD7 GeneProduct ensembl:ENSG00000171316 "" ensembl:ENSG00000171316 ncbigene:55636 hgnc.symbol:CHD7 uniprot:Q9P2D1;uniprot:E9PP20;uniprot:H0YDC1;uniprot:H0YD01 @@ -38,4 +38,3 @@ PLC Protein :9606 "" PKC Protein uniprot:A0A087X0I9 "" Neurogenin-1 Protein uniprot:F1T0H3 "" ensembl:ENSG00000181965 ncbigene:4762 hgnc.symbol:NEUROG1 uniprot:Q92886;uniprot:F1T0H3 GNRH Protein ensembl:ENSG00000147437 "" ensembl:ENSG00000147437 ncbigene:2796 hgnc.symbol:GNRH1 uniprot:P01148 -LH Protein uniprot:P01229 "" ensembl:ENSG00000104826 ncbigene:3972 hgnc.symbol:LHB uniprot:P01229;uniprot:A0A0F7RQE6 diff --git a/pathways/WP5074/WP5074.gpml b/pathways/WP5074/WP5074.gpml index 6669926fb..816752f04 100644 --- a/pathways/WP5074/WP5074.gpml +++ b/pathways/WP5074/WP5074.gpml @@ -1,8 +1,8 @@ - + Pathway for Kallmann's Syndrome da1 - + @@ -147,11 +147,11 @@ - + - + @@ -203,11 +203,11 @@ - + - + @@ -219,11 +219,11 @@ - + - + Estradiol Progesteron @@ -253,15 +253,11 @@ - - - - - + - + @@ -937,13 +933,13 @@ - + - + - + @@ -995,54 +991,15 @@ - - Kallmann syndrome - DOID:3614 - Disease - - - 23596439 - PubMed - PROK2/PROKR2 Signaling and Kallmann Syndrome. - Front Endocrinol (Lausanne) - 2013 - Dodé C - Rondard P - - - 29186351 - PubMed - Reactome diagram viewer: data structures and strategies to boost performance - PubMed - 2018 - Fabregat A, Sidiropoulos K, Viteri G, Marin-Garcia P, Ping P, Stein L, DÉustachio P, Hermjakob H - - - 32273485 - PubMed - <i>Neurog2</i>Acts as a Classical Proneural Gene in the Ventromedial Hypothalamus and Is Required for the Early Phase of Neurogenesis. - J Neurosci - 2020 - Aslanpour S - Han S - Schuurmans C - Kurrasch DM - - - 26411921 + + 15863030 PubMed - Functional Insights into Chromatin Remodelling from Studies on CHARGE Syndrome. - Trends Genet - 2015 - Basson MA - van Ravenswaaij-Arts C - - - - - FGFR1c:KAL1 [plasma membrane] - Reactome R-HSA-5654346.1 - + Cellular signaling by fibroblast growth factor receptors. + Cytokine Growth Factor Rev + 2005 + Eswarakumar VP + Lax I + Schlessinger J 21664428 @@ -1054,21 +1011,6 @@ Dwyer A Pitteloud N - - disease pathway - PW:0000013 - Pathway Ontology - - - 15863030 - PubMed - Cellular signaling by fibroblast growth factor receptors. - Cytokine Growth Factor Rev - 2005 - Eswarakumar VP - Lax I - Schlessinger J - 25985275 PubMed @@ -1086,6 +1028,17 @@ Mann F Ruhrberg C + + 32273485 + PubMed + <i>Neurog2</i>Acts as a Classical Proneural Gene in the Ventromedial Hypothalamus and Is Required for the Early Phase of Neurogenesis. + J Neurosci + 2020 + Aslanpour S + Han S + Schuurmans C + Kurrasch DM + 17054399 PubMed @@ -1111,6 +1064,49 @@ Young J Hardelin JP + + disease pathway + PW:0000013 + Pathway Ontology + + + 23596439 + PubMed + PROK2/PROKR2 Signaling and Kallmann Syndrome. + Front Endocrinol (Lausanne) + 2013 + Dodé C + Rondard P + + + + + FGFR1c:KAL1 [plasma membrane] + Reactome R-HSA-5654346.1 + + + + Kallmann syndrome + DOID:3614 + Disease + + + 29186351 + PubMed + Reactome diagram viewer: data structures and strategies to boost performance + PubMed + 2018 + Fabregat A, Sidiropoulos K, Viteri G, Marin-Garcia P, Ping P, Stein L, DÉustachio P, Hermjakob H + + + 26411921 + PubMed + Functional Insights into Chromatin Remodelling from Studies on CHARGE Syndrome. + Trends Genet + 2015 + Basson MA + van Ravenswaaij-Arts C + diff --git a/pathways/WP5074/WP5074.json b/pathways/WP5074/WP5074.json index 8c05e0da9..2e01ce40f 100644 --- a/pathways/WP5074/WP5074.json +++ b/pathways/WP5074/WP5074.json @@ -1248,7 +1248,7 @@ "stroke": "#0000ff", "strokeWidth": 1, "textAlign": "center", - "textContent": "testosterone", + "textContent": "Testosterone", "textDecoration": "none", "textOverflow": "clip", "type": [ @@ -1257,7 +1257,7 @@ "ChEBI:CHEBI:17347", "Metabolite", "CompactIdentifier:chebi:17347", - "testosterone", + "Testosterone", "Wikidata:Q1318776", "ChEBI:17347", "InChI:MUMGGOZAMZWBJJ-DYKIIFRCSA-N", @@ -1639,7 +1639,7 @@ "stroke": "#000000", "strokeWidth": 1, "textAlign": "center", - "textContent": "ProliferationSurvival", + "textContent": "Proliferation\nSurvival", "textDecoration": "none", "textOverflow": "clip", "type": [ @@ -1802,7 +1802,7 @@ "stroke": "#0000ff", "strokeWidth": 1, "textAlign": "center", - "textContent": "progesterone", + "textContent": "Progesterone", "textDecoration": "none", "textOverflow": "clip", "type": [ @@ -1811,7 +1811,7 @@ "ChEBI:CHEBI:17026", "Metabolite", "CompactIdentifier:chebi:17026", - "progesterone", + "Progesterone", "Wikidata:Q26963", "ChEBI:17026", "InChI:RJKFOVLPORLFTN-LEKSSAKUSA-N", @@ -2077,7 +2077,7 @@ "stroke": "#000000", "strokeWidth": 1, "textAlign": "center", - "textContent": "Voice breaksGrowth of muscle tissueEnlargement of genitaliaFacial, pubic & axiliary hair", + "textContent": "Voice breaks\nGrowth of muscle tissue\nEnlargement of genitalia\nFacial, pubic & axiliary hair", "textDecoration": "none", "textOverflow": "clip", "type": [ @@ -2358,7 +2358,7 @@ "stroke": "#0000ff", "strokeWidth": 1, "textAlign": "center", - "textContent": "inhibitin", + "textContent": "Inhibitin", "textDecoration": "none", "textOverflow": "clip", "type": [ @@ -2603,7 +2603,7 @@ "stroke": "#000000", "strokeWidth": 1, "textAlign": "center", - "textContent": "ProliferationDifferentiation", + "textContent": "Proliferation\nDifferentiation", "textDecoration": "none", "textOverflow": "clip", "type": [ @@ -2974,7 +2974,7 @@ "stroke": "#0000ff", "strokeWidth": 1, "textAlign": "center", - "textContent": "estradiol", + "textContent": "Estradiol", "textDecoration": "none", "textOverflow": "clip", "type": [ @@ -2983,7 +2983,7 @@ "ChEBI:CHEBI:23965", "Metabolite", "CompactIdentifier:chebi:23965", - "estradiol", + "Estradiol", "Wikidata:Q12415847", "ChEBI:23965", "InChI:VOXZDWNPVJITMN-WKUFJEKOSA-N", @@ -3062,7 +3062,7 @@ "stroke": "#0000ff", "strokeWidth": 1, "textAlign": "center", - "textContent": "oestrogen", + "textContent": "Estrogen", "textDecoration": "none", "textOverflow": "clip", "type": [ @@ -3071,7 +3071,7 @@ "ChEBI:CHEBI:50114", "Metabolite", "CompactIdentifier:chebi:50114", - "oestrogen", + "Estrogen", "Wikidata:Q277954", "ChEBI:50114" ], @@ -3294,49 +3294,6 @@ "width": 0, "zIndex": 12288 }, - "e6638": { - "drawAs": "rect", - "fill": "#ffffff", - "fontFamily": "Arial", - "fontSize": 12, - "fontStyle": "normal", - "fontWeight": "normal", - "gpmlElementName": "DataNode", - "height": 16.500275183676077, - "id": "e6638", - "kaavioType": "SingleFreeNode", - "lineHeight": 1.1, - "overflow": "hidden", - "padding": 8, - "stroke": "#000000", - "strokeWidth": 1, - "textAlign": "center", - "textContent": "LH", - "textDecoration": "none", - "textOverflow": "clip", - "type": [ - "DataNode", - "SingleFreeNode", - "Uniprot-TrEMBL:P01229", - "Protein", - "CompactIdentifier:uniprot:P01229", - "LH", - "Ensembl:ENSG00000104826", - "Entrez Gene:3972", - "HGNC:LHB", - "UniProt:P01229", - "UniProt:A0A0F7RQE6" - ], - "verticalAlign": "middle", - "whiteSpace": "pre", - "width": 57.108314831729196, - "wpType": "Protein", - "x": 3523, - "xrefDataSource": "Uniprot-TrEMBL", - "xrefIdentifier": "P01229", - "y": 1775, - "zIndex": 32904 - }, "e8ef7": { "burrs": [ "fdeee" @@ -3636,7 +3593,7 @@ "stroke": "#0000ff", "strokeWidth": 1, "textAlign": "center", - "textContent": "testosterone", + "textContent": "Testosterone", "textDecoration": "none", "textOverflow": "clip", "type": [ @@ -3645,7 +3602,7 @@ "ChEBI:CHEBI:17347", "Metabolite", "CompactIdentifier:chebi:17347", - "testosterone", + "Testosterone", "Wikidata:Q1318776", "ChEBI:17347", "InChI:MUMGGOZAMZWBJJ-DYKIIFRCSA-N", @@ -3965,7 +3922,7 @@ "stroke": "#000000", "strokeWidth": 1, "textAlign": "center", - "textContent": "Broadening of hipsMenstruation beginsDevelopment of breastsPubic & axiliary hair", + "textContent": "Broadening of hips\nMenstruation begins\nDevelopment of breasts\nPubic & axiliary hair", "textDecoration": "none", "textOverflow": "clip", "type": [ @@ -4570,7 +4527,7 @@ "stroke": "#000000", "strokeWidth": 1, "textAlign": "center", - "textContent": "ProliferationDifferentiationSurvivalCytoskeletal organization Migration", + "textContent": "Proliferation\nDifferentiation\nSurvival\nCytoskeletal organization\nMigration", "textDecoration": "none", "textOverflow": "clip", "type": [ @@ -9079,7 +9036,7 @@ "id": "publicationXrefa56", "source": "J Clin Invest", "standardName": "Dysfunctional SEMA3E signaling underlies gonadotropin-releasing hormone neuron deficiency in Kallmann syndrome.", - "textContent": "6", + "textContent": "5", "type": [ "PublicationXref", "PubMed:25985275" @@ -9167,7 +9124,7 @@ "id": "publicationXrefda1", "source": "Trends Genet", "standardName": "Functional Insights into Chromatin Remodelling from Studies on CHARGE Syndrome.", - "textContent": "5", + "textContent": "6", "type": [ "PublicationXref", "PubMed:26411921" @@ -9408,7 +9365,6 @@ "d8557", "e1dd4", "c57c7", - "e6638", "b7b66", "d6706", "d0c79", @@ -9418,17 +9374,17 @@ "e95e9", "d83e5" ], - "dataSourceVersion": "WP5074_r135691", + "dataSourceVersion": "WP5074_r135697", "displayName": "Kallmann syndrome", "drawAs": "rect", "fill": "white", "fontSize": 12, "fontWeight": "bold", "gpmlElementName": "Pathway", - "height": 1821.500275183676, + "height": 1237.1643878729974, "id": "WP5074", "kaavioType": "Group", - "lastModified": "20241027001937", + "lastModified": "20241027151949", "name": "Kallmann syndrome", "organism": "Homo sapiens", "padding": 5, @@ -9437,13 +9393,13 @@ "stroke": "black", "strokeWidth": 0, "textAlign": "left", - "textContent": "Name: Kallmann syndrome\nLast Modified: 20241027001937\nOrganism: Homo sapiens", + "textContent": "Name: Kallmann syndrome\nLast Modified: 20241027151949\nOrganism: Homo sapiens", "type": [ "Pathway", "http://identifiers.org/pw/PW:0000013" ], "verticalAlign": "top", - "width": 3610.1083148317293, + "width": 2459.416843446774, "x": 0, "y": 0, "zIndex": 0 diff --git a/pathways/WP5074/WP5074.png b/pathways/WP5074/WP5074.png index 456c407e7..2029c984c 100644 Binary files a/pathways/WP5074/WP5074.png and b/pathways/WP5074/WP5074.png differ diff --git a/pathways/WP5074/WP5074.svg b/pathways/WP5074/WP5074.svg index a764af3d9..600e4bb2c 100644 --- a/pathways/WP5074/WP5074.svg +++ b/pathways/WP5074/WP5074.svg @@ -1,5 +1,5 @@ - + @@ -10,46 +10,46 @@ - + - + - + - + - + - + - + - + - + - + - + - + - + - + @@ -466,8 +466,8 @@ - - + + @@ -828,22 +828,28 @@ - + - ProliferationDifferentiation + Proliferation + Differentiation - + - ProliferationSurvival + Proliferation + Survival - + - ProliferationDifferentiationSurvivalCytoskeletal organization Migration + Proliferation + Differentiation + Survival + Cytoskeletal organization + Migration @@ -1165,24 +1171,27 @@ SOX10 - + - Voice breaksGrowth of muscle tissueEnlargement of genitaliaFacial, pubic & axiliary hair + Voice breaks + Growth of muscle tissue + Enlargement of genitalia + Facial, pubic & axiliary hair - + - estradiol + Estradiol - + - progesterone + Progesterone @@ -1269,16 +1278,19 @@ ANOS1 - + - testosterone + Testosterone - + - Broadening of hipsMenstruation beginsDevelopment of breastsPubic & axiliary hair + Broadening of hips + Menstruation begins + Development of breasts + Pubic & axiliary hair @@ -1307,10 +1319,10 @@ - + - oestrogen + Estrogen @@ -1335,16 +1347,16 @@ - + - testosterone + Testosterone - + - inhibitin + Inhibitin @@ -1436,12 +1448,6 @@ - - - - LH - - @@ -1483,7 +1489,7 @@ Name: Kallmann syndrome - Last Modified: 20241027001937 + Last Modified: 20241027151949 Organism: Homo sapiens diff --git a/pathways/WP5323/WP5323.gpml b/pathways/WP5323/WP5323.gpml index 731dd99e1..a8548f4dc 100644 --- a/pathways/WP5323/WP5323.gpml +++ b/pathways/WP5323/WP5323.gpml @@ -1,5 +1,5 @@ - + This model was constructed integrating the Fatty acid transporters (Homo sapiens) metapathway (WP5061), the Cholesterol metabolism (Homo sapiens) (WP5304) and the KEGG Cholesterol metabolism pathway (map04979) as well as information from the literature. @@ -1597,6 +1597,11 @@ https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:2690 + + + + + @@ -1628,11 +1633,6 @@ https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:2690 - - - - - @@ -1656,7 +1656,7 @@ https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:2690 - + @@ -1695,13 +1695,13 @@ https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:2690 - + - - - - - + + + + + @@ -1726,6 +1726,11 @@ https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:2690 Siliart B Dumon H + + classic metabolic pathway + PW:0000002 + Pathway Ontology + 12856180 PubMed @@ -1737,20 +1742,15 @@ https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:2690 Stahl A - classic metabolic pathway - PW:0000002 - Pathway Ontology + hepatocyte + CL:0000182 + Cell Type centrilobular region hepatocyte CL:0019029 Cell Type - - hepatocyte - CL:0000182 - Cell Type - diff --git a/pathways/WP5323/WP5323.json b/pathways/WP5323/WP5323.json index 62d4231ac..787ac0520 100644 --- a/pathways/WP5323/WP5323.json +++ b/pathways/WP5323/WP5323.json @@ -750,7 +750,6 @@ "stroke": "#808080", "strokeWidth": 1, "textAlign": "center", - "textContent": "VDAC1:STAR", "type": [ "Group", "Complex", @@ -1074,9 +1073,9 @@ "verticalAlign": "bottom", "whiteSpace": "pre", "width": 477.93259904652496, - "x": 1500.2340676201359, - "y": 390.1666666666671, - "zIndex": 11 + "x": 1499.2340676201359, + "y": 395.1666666666671, + "zIndex": -6 }, "ca11": { "cellularComponent": "Cell", @@ -1692,8 +1691,8 @@ "verticalAlign": "bottom", "whiteSpace": "pre", "width": 419, - "x": 2011.1666666666706, - "y": 438.50000000000034, + "x": 2013.6666666666706, + "y": 439.75000000000034, "zIndex": 18 }, "cb2e1": { @@ -1827,7 +1826,6 @@ "stroke": "#808080", "strokeWidth": 1, "textAlign": "center", - "textContent": "LDLR", "type": [ "Group", "Complex", @@ -1857,7 +1855,6 @@ "stroke": "#808080", "strokeWidth": 1, "textAlign": "center", - "textContent": "LDLR", "type": [ "Group", "Complex", @@ -1887,7 +1884,6 @@ "stroke": "#808080", "strokeWidth": 1, "textAlign": "center", - "textContent": "APOE:LRP1", "type": [ "Group", "Complex", @@ -1917,7 +1913,6 @@ "stroke": "#808080", "strokeWidth": 1, "textAlign": "center", - "textContent": "LDLR", "type": [ "Group", "Complex", @@ -1948,7 +1943,6 @@ "stroke": "#808080", "strokeWidth": 1, "textAlign": "center", - "textContent": "APOB:LDLR:LDLRAP1", "type": [ "Group", "Complex", @@ -15382,6 +15376,7 @@ } ], "contains": [ + "ca10", "edf38", "ca13", "ca16", @@ -15389,7 +15384,6 @@ "ca6", "ca7", "ca20", - "ca10", "ca23", "ca17", "ca21", @@ -15605,7 +15599,7 @@ "eefd9", "c7ca1" ], - "dataSourceVersion": "WP5323_r135588", + "dataSourceVersion": "WP5323_r135704", "displayName": "Fatty acid and lipoprotein transport in hepatocytes", "drawAs": "rect", "fill": "white", @@ -15615,7 +15609,7 @@ "height": 1529.6745308068823, "id": "WP5323", "kaavioType": "Group", - "lastModified": "20241004124559", + "lastModified": "20241027164019", "name": "Fatty acid and lipoprotein transport in hepatocytes", "organism": "Homo sapiens", "padding": 5, @@ -15624,7 +15618,7 @@ "stroke": "black", "strokeWidth": 0, "textAlign": "left", - "textContent": "Name: Fatty acid and lipoprotein transport in hepatocytes\nLast Modified: 20241004124559\nOrganism: Homo sapiens", + "textContent": "Name: Fatty acid and lipoprotein transport in hepatocytes\nLast Modified: 20241027164019\nOrganism: Homo sapiens", "type": [ "Pathway", "http://identifiers.org/pw/PW:0000002" diff --git a/pathways/WP5323/WP5323.png b/pathways/WP5323/WP5323.png index cc99e2edb..cff029bfc 100644 Binary files a/pathways/WP5323/WP5323.png and b/pathways/WP5323/WP5323.png differ diff --git a/pathways/WP5323/WP5323.svg b/pathways/WP5323/WP5323.svg index 7b3536f6a..f85cfabfd 100644 --- a/pathways/WP5323/WP5323.svg +++ b/pathways/WP5323/WP5323.svg @@ -4,17 +4,17 @@ ]]> + + + + + - - - - - @@ -27,18 +27,18 @@ - - - - - - + + + + + + @@ -489,8 +489,16 @@ - + + + + + + + Lysosome + + @@ -524,14 +532,6 @@ - - - - - - Lysosome - - @@ -547,7 +547,7 @@ - + @@ -1760,7 +1760,7 @@ remnant - + @@ -1780,11 +1780,8 @@ LDLR - - APOB:LDLR:LDLRAP1 - - + @@ -1798,11 +1795,8 @@ PCSK9 - - LDLR - - + @@ -1816,11 +1810,8 @@ LRP1 - - APOE:LRP1 - - + @@ -1834,11 +1825,8 @@ PCSK9 - - LDLR - - + @@ -1852,9 +1840,6 @@ PCSK9 - - LDLR - @@ -2075,7 +2060,7 @@ SOAT - + @@ -2089,9 +2074,6 @@ STAR - - VDAC1:STAR - @@ -2211,7 +2193,7 @@ Name: Fatty acid and lipoprotein transport in hepatocytes - Last Modified: 20241004124559 + Last Modified: 20241027164019 Organism: Homo sapiens