This repo is to organize and maintain the code/files associated with the rDNA CN manuscript. We will provide a link to the published manuscript when it becomes available.
- Code used to generate the figures and analyze the data is located within the figure_code folder.
- Code used to estimate rDNA CN from whole genome sequencing of yeast strains is located within the genomic_sequencing_pipeline folder.
- Computer vision models that were used to analyze timelapse images of aging yeast are located withing a submodule found in the cv_models repository.
- Images and data tables used to generate figures are located within the data folder.
If you find any of this code/analysis useful in your own work, please cite the manuscript as:
Hotz M, Thayer NH, Hendrickson DG, Schinski EL, Xu J and Gottschling DE. (2022) rDNA array length is a major determinant of replicative lifespan in budding yeast PNAS 119 (15) e2119593119 https://doi.org/10.1073/pnas.2119593119
