This program aims to search for a water molecule's energy positions in cavities of proteins having minimum energy. Read Zhang and Hermans' paper for more information: Zhang & Hermans.
Dowser's oficial link: http://danger.med.unc.edu/hermans/dowser/dowser.htm
However, it is hardly ever available, which is why I decided to upload the Dowser code to ensure program availability.
Prior to installing Dowser, type:
$ sudo apt update
$ sudo apt install build-essential
You need gfotran compiler in linux to install Dowser. However, gfortran 77 is no longer available as a g77. Of course you could find it, but it is advisable to use the latest gfortran compiler, like Gfortran e.g.:
$ sudo apt-get install gfortran
You have to name your gfortran compiler absolute path as g77 in other Dowser versions, e.g.:
$ sudo cp /usr/bin/gfortran /usr/bin/g77
The gfortran compiler has to be named gfortran for Dowser in this GitHub repository version (https://github.com/caraortizmah/dowser.git).
You have to install csh prior to install Dowser, e.g.:
$ sudo apt update
$ sudo apt install csh
Download Dowser by typing:
$ git clone https://github.com/caraortizmah/dowser.git
Once you have downloaded the code, type:
$ cd $PATH_dowser/
$ chmod u+x Install
$ chmod u+x bin/dowser
$ ./Install
When installation ends, you need to export the Dowser program location to your PATH. For BASH, edit your .bashrc or .bash_profile file by typing:
export DOWSER= # write the Dowser absolute installation path here
export DOW_MACH=linux
export PATH=$PATH:$DOWSER/bin:$DOWSER/bin/$DOW_MACH
For CSH type:
setenv DOWSER # write the Dowser absolute installation path here
setenv DOW_MACH linux
set path = ( $path $DOWSER/bin $DOWSER/bin/$DOW_MACH )
And then, source the edited file (whichever in your case):
$ source .bashrc
or
$ source .bash_profile
That's all there is to it.
For further information about the installation go to: http://somagliablog.blogspot.com/2013/11/install-dowser-program.html