Permuthon is a Python-based esoteric programming language which permutes your variables randomly on every line of code. Additionally, it forces you to use one-char variable names.
The language prevents you from cheating by blocking multiple instructions on one line. An 'IDE' which shows which variable is which is also available.
For example, the following is an implementation of Fibbonaci in Permuthon:
a = 0
b = 1
while True:
print(z)
c = v + u
d = p
t = s
sleep(1)