Re-build website

data/clinical_trials_clean.csv

@@ -1000,7 +1000,7 @@ Exclusion Criteria:
 History of other acquired or progressive neurological disease.
 Significant language comprehension impairments (per performance on the CAT - individuals will be excluded if their spoken language comprehension mean modality T- score on the CAT falls below 40).
 Unmanaged drug / alcohol dependence.
-Severe diagnosed mood or behavioral disorders that require specialize mental health interventions.","No","18 Years","All","Pittsburgh","15260","Pennsylvania","William Evans","United States",1,"no",-79.958065,40.44047,2023-09-21
+Severe diagnosed mood or behavioral disorders that require specialize mental health interventions.","No","18 Years","All","Pittsburgh","15260","Pennsylvania","William Evans","United States",1,"no",-79.955683,40.443921,2023-09-21
 "41",37,"Modulating Intensity and Dosage of Aphasia Scripts","Aphasia","September 21, 2020","NCT04138940","Shirley Ryan AbilityLab Chicago Illinois United States","Shirley Ryan AbilityLab","Recruiting","The purpose of this study is to evaluate how changing conditions of speech-language treatment (namely, amount of repetition and distribution of practice schedule) affects the language outcome of participants with aphasia following a stroke. Using a computer based speech and language therapy program, participants will practice conversational scripts that are either short or long. Participants will practice for either 2 weeks (5 days a week) or for 5 weeks (2 days a week).","Determining the optimal intensity of treatment is essential to the design and implementation of any treatment program for aphasia. Yet, treatment intensity is a complex construct and information on the variables modulating it remain ambiguous and limited. Studies reported in the neuroscience and clinical literature support the need for intensive treatment to induce long-term neuroplastic changes while the cognitive psychology literature suggests that learning is best maintained with distributed schedules. A few studies have looked at dose parameters for single word naming tasks, but there is limited evidence regarding dose parameters for treatments that focus on training the production of larger units, such as sentences or even connected discourse. One approach that is frequently used clinically and has evidence for its efficacy is script training. Little is currently known regarding the optimum dose of script training (i.e., the number of repetitions over time of each sentence within the script) that is required to promote the best outcomes.
 
 This study investigates the effects of modulating stimulus variables, specifically stimulus practice distribution and stimulus repetition. We use a baseline script treatment that has experimental support regarding its efficacy, and that allows the manipulation of these variables. To ensure independence and fidelity, treatment is provided in a controlled computer environment (desktop and tablet). To avoid clinician-related variables such as expertise and personality factors that may influence treatment, sentences are modeled during treatment by an anthropomorphic agent with high visual speech intelligibility and affective expressions.
@@ -1064,7 +1064,7 @@ Exclusion Criteria:
 History of other acquired or progressive neurological disease.
 Significant language comprehension impairments (per performance on the CAT - individuals will be excluded if their spoken language comprehension mean modality T- score on the CAT falls below 40).
 Unmanaged drug / alcohol dependence.
-Severe diagnosed mood or behavioral disorders that require specialize mental health interventions.","No","18 Years","All","Pittsburgh","15260","Pennsylvania","William Evans","United States",1,"no",-79.958065,40.44047,2023-09-01
+Severe diagnosed mood or behavioral disorders that require specialize mental health interventions.","No","18 Years","All","Pittsburgh","15260","Pennsylvania","William Evans","United States",1,"no",-79.955683,40.443921,2023-09-01
 "44",40,"Improving Aphasia Using Electrical Brain Stimulation","Stroke Aphasia","July 12, 2021","NCT04963803","Syracuse University Syracuse New York United States","Syracuse University","Recruiting","Language and communication are essential for almost every aspect of human life, but for people who have aphasia, a language processing disorder that can occur after stroke or brain injury, even simple conversations can become a formidable challenge. Speech and language therapy can help people recover their language ability, but often requires months or even years of therapy before a person is able to overcome these challenges. This research will investigate non-invasive brain stimulation as a way to enhance the effects of speech and language therapy, which may ultimately lead to better and faster recovery from stroke and aphasia. The investigators hypothesize that participants with aphasia who receive speech and language therapy paired with active electrical brain stimulation will improve significantly more on a language comprehension task than those who receive speech and language therapy paired with sham stimulation.",NA,"tDCS attention language speech-language therapy","Interventional","Inclusion Criteria:
 
 18 years or older.

docs/about.html

@@ -2370,7 +2370,7 @@ <h1>About this Website</h1>
 
 <div class="d-article">
 <p>This website was built primarily using data from the <a href="https://clinicaltrials.gov/"><em>clinicaltrials.gov</em></a> API to identify studies that included a keyword or condition listing of Aphasia (excluding primary progressive aphasia and other dementias.)</p>
-<p>It was last updated on December 18 2023</p>
+<p>It was last updated on December 25 2023</p>
 <p>To add your study to this website, <a href="https://clinicaltrials.gov/ct2/manage-recs">submit the study</a> to <em>clinicaltrials.gov</em>. This has <a href="https://clinicaltrials.gov/ct2/manage-recs/background">a number of benefits for the research community and general public</a>. While submission to <em>clinicaltrials.gov</em> is required for funded clinical trials in the US, voluntary submission is also permitted for other studies.</p>
 <p>If submitting your study to clinicaltrials.gov is not feasible or is overly burdensome, you can add an IRB-approved flyer to the website by <a href="https://github.com/rbcavanaugh/find-aphasia-research/issues">submitting an issue on github.com</a>. Note that you will will need to create a github account. This is free and helps me keep track of submissions.</p>
 <p>If you notice an error on the website, please <a href="https://robcavanaugh.com">contact me</a> or <a href="https://github.com/rbcavanaugh/find-aphasia-research/issues">file an issue here</a>.</p>

docs/data/clinical_trials_clean.csv

@@ -1000,7 +1000,7 @@ Exclusion Criteria:
 History of other acquired or progressive neurological disease.
 Significant language comprehension impairments (per performance on the CAT - individuals will be excluded if their spoken language comprehension mean modality T- score on the CAT falls below 40).
 Unmanaged drug / alcohol dependence.
-Severe diagnosed mood or behavioral disorders that require specialize mental health interventions.","No","18 Years","All","Pittsburgh","15260","Pennsylvania","William Evans","United States",1,"no",-79.958065,40.44047,2023-09-21
+Severe diagnosed mood or behavioral disorders that require specialize mental health interventions.","No","18 Years","All","Pittsburgh","15260","Pennsylvania","William Evans","United States",1,"no",-79.955683,40.443921,2023-09-21
 "41",37,"Modulating Intensity and Dosage of Aphasia Scripts","Aphasia","September 21, 2020","NCT04138940","Shirley Ryan AbilityLab Chicago Illinois United States","Shirley Ryan AbilityLab","Recruiting","The purpose of this study is to evaluate how changing conditions of speech-language treatment (namely, amount of repetition and distribution of practice schedule) affects the language outcome of participants with aphasia following a stroke. Using a computer based speech and language therapy program, participants will practice conversational scripts that are either short or long. Participants will practice for either 2 weeks (5 days a week) or for 5 weeks (2 days a week).","Determining the optimal intensity of treatment is essential to the design and implementation of any treatment program for aphasia. Yet, treatment intensity is a complex construct and information on the variables modulating it remain ambiguous and limited. Studies reported in the neuroscience and clinical literature support the need for intensive treatment to induce long-term neuroplastic changes while the cognitive psychology literature suggests that learning is best maintained with distributed schedules. A few studies have looked at dose parameters for single word naming tasks, but there is limited evidence regarding dose parameters for treatments that focus on training the production of larger units, such as sentences or even connected discourse. One approach that is frequently used clinically and has evidence for its efficacy is script training. Little is currently known regarding the optimum dose of script training (i.e., the number of repetitions over time of each sentence within the script) that is required to promote the best outcomes.
 
 This study investigates the effects of modulating stimulus variables, specifically stimulus practice distribution and stimulus repetition. We use a baseline script treatment that has experimental support regarding its efficacy, and that allows the manipulation of these variables. To ensure independence and fidelity, treatment is provided in a controlled computer environment (desktop and tablet). To avoid clinician-related variables such as expertise and personality factors that may influence treatment, sentences are modeled during treatment by an anthropomorphic agent with high visual speech intelligibility and affective expressions.
@@ -1064,7 +1064,7 @@ Exclusion Criteria:
 History of other acquired or progressive neurological disease.
 Significant language comprehension impairments (per performance on the CAT - individuals will be excluded if their spoken language comprehension mean modality T- score on the CAT falls below 40).
 Unmanaged drug / alcohol dependence.
-Severe diagnosed mood or behavioral disorders that require specialize mental health interventions.","No","18 Years","All","Pittsburgh","15260","Pennsylvania","William Evans","United States",1,"no",-79.958065,40.44047,2023-09-01
+Severe diagnosed mood or behavioral disorders that require specialize mental health interventions.","No","18 Years","All","Pittsburgh","15260","Pennsylvania","William Evans","United States",1,"no",-79.955683,40.443921,2023-09-01
 "44",40,"Improving Aphasia Using Electrical Brain Stimulation","Stroke Aphasia","July 12, 2021","NCT04963803","Syracuse University Syracuse New York United States","Syracuse University","Recruiting","Language and communication are essential for almost every aspect of human life, but for people who have aphasia, a language processing disorder that can occur after stroke or brain injury, even simple conversations can become a formidable challenge. Speech and language therapy can help people recover their language ability, but often requires months or even years of therapy before a person is able to overcome these challenges. This research will investigate non-invasive brain stimulation as a way to enhance the effects of speech and language therapy, which may ultimately lead to better and faster recovery from stroke and aphasia. The investigators hypothesize that participants with aphasia who receive speech and language therapy paired with active electrical brain stimulation will improve significantly more on a language comprehension task than those who receive speech and language therapy paired with sham stimulation.",NA,"tDCS attention language speech-language therapy","Interventional","Inclusion Criteria:
 
 18 years or older.