pten

Comprehensive bioinformatics analysis of the human PTEN gene and protein using publicly available databases and computational tools.

Comprehensive molecular dynamics simulations and drug design analysis for PTEN protein: workflows include protein dynamics, binding site detection, ligand screening, and filtering for therapeutic discovery.

In silico analysis of selected human PTEN variants using SIFT, PolyPhen-2, I-Mutant 2.0, Project HOPE, and ClinVar to investigate their predicted functional, structural, stability, and clinical significance.

Machine learning and structural dynamics workflows for interpreting PTEN missense mutations shared by cancer and ASD.