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A statistical tool for power calculation of predictive biomarker in prospective and retrospective studies.

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PowerPredictiveBiomarker

The tool is for power calculation of predictive biomarker. Calculation requires a series of parameters to to determine subgroup proportion and subgroup censoring rate. Depending on study type (prospective or retrospective study), parameter setting is different (reference: Strategies for power calculations in predictive biomarker studies in survival data; Chen et al; Oncotarget; 2016; in press).

Features

  • The shiny applictaion for power calculation of predictive biomarker generates a statistical plan to justify the sample size

Installation

Simply run the following from an R console:

if (!require("devtools"))
  install.packages("devtools")
devtools::install_github("dungtsa/PowerPredictiveBiomarker",force = TRUE)

Getting Started

require("PowerPredictiveBiomarker")
PowerPredictiveBiomarker.shiny()

Snapshot of shiny app: initial snapshot of shiny app: initial


Snapshot of shiny app: output snapshot of shiny app: output


Snapshot of shiny app: output in Word format (through "download" button) snapshot of shiny app: output

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A statistical tool for power calculation of predictive biomarker in prospective and retrospective studies.

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