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Assessing the effectiveness of endocrine therapy in breast cancer using RNAseq data

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RNAseq

This repository contains the data, source code and markdown report for project of the course BIO-463 "Genomics & Bioinformatics".

This report have for aim the understanding and reproduction of specific RNAseq experiment data analysis. The analysis was made from the resuts of "A Preclinical Model for Eostrogen receptor alpha (ERα) positive Breast Cancer Points to the Epithelial Microenvironment as Determinant of Luminal Phenotype and Hormone Response", by Sflomos, G. et al. published in Cancer Cell (2016).

The dataset was composed of more than 60'000 protein coding genes log-transformed expression (counts). All the work was performed using R.

The results can be found in a report realized with RMarkdown here.

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Assessing the effectiveness of endocrine therapy in breast cancer using RNAseq data

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